55 completed, 41 recruiting, 26 unknown, 11 active not recruiting. 44 Not applicable, 30 Phase 2, 16 Phase 1, 5 Phase 3, 2 Early Phase 1.
Follow Nerve Degeneration: new trials by email Literature Review of Nerve Degeneration trials Research Report on Nerve Degeneration
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vestibular Stimulation in Sleep for Neurorehabilitation Patients Somnomat - rocking bed providing vestibular stimulation during sleep - Memory Deficit Aquired Due to the Disease, e.g. Stroke, Neurodegeneration, Inflammatory Disease of CNS, Traumatic Brain Injury | Not applicable | Not yet recruiting | Cereneo AG | 20 | 2027-02-03 | 2026-11-03 |
| Brain Iron in Beta-Propeller Protein Associated Neurodegeneration (BPAN) Standardized brain MRI including specific sequences usable for Quantitative Susceptibility Mapping (QSM) - Neurodegeneration With Brain Iron Accumulation (NBIA), Iron Metabolism Disorders | Not applicable | Not yet recruiting | University Hospital, Bordeaux | 3 | 2026-12-01 | 2026-10-09 |
| Passive Versus Active Music Therapy Parkinson's Disease Passive music therapy, Active music therapy - Parkinson Disease (PD) | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 28 | 2026-11-01 | 2026-10-08 |
| Testing Effectiveness of a Stochastic Noise Stimulator to Immediately Improve Balance and Gait Subperceptual Stimulus, Sham Comparator - Vestibular Disorder, Aging | Not applicable | Recruiting | Massachusetts Eye and Ear Infirmary | 120 | 2026-09-25 | 2026-06-23 |
| Magnetic Resonance Imaging of Cerebral Connectivity and Volume in Neurodegeneration and Glaucoma MRI - Glaucoma | Not applicable | Recruiting | University Hospital, Bordeaux | 100 | 2026-08-28 | 2026-09-03 |
| MK-0947 PN-002: An Open-label Study to Evaluate Brain α-synuclein Deposition Using Positron Emission Tomography (PET) and [¹⁸F]MK-0947 in Participants With Parkinson's Disease (PD) [¹⁸F]MK-0947 - Parkinsons Disease (PD), Healthy Elderly Volunteers | Phase 1 | Recruiting | XingImaging, LLC | 18 | 2026-08-25 | 2026-10-19 |
| Developing a Comprehensive Biomarker Panel for Monitoring Progression and Early Detection in ALS Patients peripheral venous blood collection, collection of medical data related to patient care - ALS (Amyotrophic Lateral Sclerosis) | Not yet recruiting | University Hospital, Montpellier | 200 | 2026-08-01 | 2026-07-30 | |
| Test-retest Trial With [11C]MODAG-005 in PD or MSA and AMHC - Pilot Phase [11C]MODAG-005 - Parkinson Disease (PD), MSA - Multiple System Atrophy | Early Phase 1 | Recruiting | MODAG GmbH | 9 | 2026-07-29 | 2026-07-31 |
| Alzheimer's Tau Platform: Master Protocol AADvac1, Tau2 - Preclinical Alzheimer's Disease, Alzheimer Disease | Phase 2 | Recruiting | Paul S. Aisen | 900 | 2026-07-06 | 2026-10-26 |
| Retinal OCT Changes and Biomarkers in Drug-Resistant Epilepsy Epilepsy (Treatment Refractory), Epilepsy | Enrolling by invitation | Kemal Tutkavul | 250 | 2026-07-01 | 2026-07-21 | |
| AV-1980R (Tau Vaccine) in Preclinical Alzheimer's Disease (TAURUS-1980) AV-1980R 20 µg, AV-1980R 60 µg, AV-1980R 180 µg - Alzheimer Disease, Preclinical Alzheimer's Disease | Phase 1 | Recruiting | Institute for Molecular Medicine | 48 | 2026-06-23 | 2026-08-21 |
| SGLT2 Inhibitors and Cognitive Function in Adults With Type 2 Diabetes (SaveMinD) SGLT2 Inhibitor, Standard Diabetes Care - Type 2 Diabetes Mellitus (T2DM), Cognitive Dysfunction | Not applicable | Active not recruiting | University of Primorska | 200 | 2026-06-20 | 2026-07-10 |
| Neuromodulation and fMRI in Neurodegenerative Diseases Study Transcranial Alternating Current Stimulation - Mild Cognitive Impairment, Traumatic Brain Injury | Not applicable | Not yet recruiting | Sunnybrook Health Sciences Centre | 30 | 2026-06-01 | 2026-05-01 |
| Proximal Nerve Cryoablation Versus Perineuroma Cryoablation for Chronic Neuroma Pain After Combat-Related Amputation Perineuroma Cryoablation, Proximal Nerve Cryoablation - Neuroma, Cryoablation | Not applicable | Completed | Ukrainian Society of Regional Anesthesia and Pain Therapy | 50 | 2026-05-23 | 2026-10-26 |
| Efficacy of Repetitive Transcranial Magnetic Stimulation for Improving Depressive Symptoms in Patients With Parkinson's Disease Repetitive Transcranial Magnetic Stimulation (rTMS), Sham Repetitive Transcranial Magnetic Stimulation (Sham rTMS) - Parkinson's Disease, Depression | Not applicable | Enrolling by invitation | Ho-Won Lee | 50 | 2026-05-04 | 2026-10-29 |
| Auditory Sleep Stimulation or Sham in People With Parkinson Disease Mild Cognitive Impairment During Cognitive Training Phase-Targeted Auditory Stimulation (PTAS), Digital Cognitive Training (CogT) - Parkinson's Disease, Mild Cognitive Impairment | Not applicable | Recruiting | University of Zurich | 50 | 2026-04-22 | 2026-04-30 |
| Kisspeptin to Quantify GnRH Neuronal Function in Health and Disease Kisspeptin 112-121 - Reproductive Disorder, Neurodegeneration | Phase 1 | Recruiting | Stephanie B. Seminara, MD | 40 | 2026-03-10 | 2026-07-13 |
| Protecting the Brain From Post-Stroke Cognitive Impairment and Dementia With Multimodal Exercise Training Multimodal Training, Balance, Toning and Stretching - Stroke | Not applicable | Recruiting | McGill University | 120 | 2026-03-09 | 2026-07-06 |
| A Trial to Test the Use of Dapansutrile, an Anti-inflammatory Medication, in People With Parkinson's Disease dapansutrile, placebo - Parkinson Disease | Phase 2 | Recruiting | Cambridge University Hospitals NHS Foundation Trust | 36 | 2026-02-02 | 2026-11-03 |
| Prevalence of Mild Cognitive Impairment and Dementia in Patients Admitted to Non-neurological Rehabilitation Wards Cognitive and clinical screening, Extended neuropsychological assessment, Blood biomarker sampling and APOE genotyping - MCI, Mild Cognitive Impairment (MCI) | Not applicable | Recruiting | Fondazione Don Carlo Gnocchi ETS | 384 | 2026-01-20 | 2026-08-10 |
Showing 20 of 148. Sign in to see all of them.
Parkinson Disease (30) · Cognitive Dysfunction (24) · Alzheimer Disease (21) · Multiple Sclerosis (20) · Amyotrophic Lateral Sclerosis (12) · Dementia (12) · Neurodegenerative Diseases (12) · Inflammation (11) · Neuroinflammatory Diseases (9) · REM Sleep Behavior Disorder (9) · Aphasia, Primary Progressive (6) · Frontotemporal Dementia (6) · Supranuclear Palsy, Progressive (6) · Mitochondrial Diseases (5)
Pathological Conditions, Signs and Symptoms (148) · Pathologic Processes (147) · Nervous System Diseases (117) · Central Nervous System Diseases (91) · Brain Diseases (81) · Neurodegenerative Diseases (61) · Mental Disorders (56) · Neurocognitive Disorders (43) · Basal Ganglia Diseases (37) · Nutritional and Metabolic Diseases (36) · Movement Disorders (35) · Metabolic Diseases (34) · Synucleinopathies (33) · Parkinsonian Disorders (30) · Dementia (25)
Magnetic Resonance Spectroscopy (4) · Tomography, Optical Coherence (4) · 2-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole (3) · Spinal Puncture (3) · Blood Specimen Collection (2) · Dextromethorphan (2) · Memantine (2) · Speech Therapy (2) · THK5351 (2) · Transcranial Magnetic Stimulation (2) · copper histidine (2) · idebenone (2) · 2-Hydroxypropyl-beta-cyclodextrin (1) · AADvac1 (1) · Acetazolamide (1)
Chinese University of Hong Kong (5) · University of Zurich (4) · Clene Nanomedicine (3) · Johns Hopkins University (3) · National Institute of Neurological Disorders and Stroke (NINDS) (3) · University of Exeter (3) · University of Reading (3) · VA Office of Research and Development (3) · Brainstorm-Cell Therapeutics (2) · Charite University, Berlin, Germany (2) · Christian Baumann (2) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (2) · IRCCS San Raffaele (2) · Leiden University Medical Center (2) · Massachusetts General Hospital (2)
United States (53) · Italy (12) · United Kingdom (11) · France (9) · Switzerland (8) · Germany (7) · Turkey (Türkiye) (7) · Hong Kong (5) · Israel (4) · South Korea (4) · Canada (3) · China (3) · Denmark (3) · Netherlands (3) · Spain (3)
Kyrana Tsapkini, PhD (3) · Jeremy PE Spencer, PhD (2) · Jihui Zhang, PhD (2) · Madeleine E. Hackney, PhD (2) · Michele Tagliati, MD, FAAN (2) · Orla Hardiman, BSc MB BCh BAO MD FRCPI FAAN (2) · Shirley Xin Li, PhD (2) · Taosheng Huang (2) · Tzu-Yun Wang (2) · Vincent Chung Tong Mok, MBChB (2) · Yun Kwok Wing, MBChB (2) · Adam Boxer, MD, PhD (1) · Andreas Luft, Prof. Dr. med. (1) · Angelina Maric, PhD (1)
PMID 17562928, PMID 26751635, PMID 36602886, PMID 38588457, PMID 10214756, PMID 10406987, PMID 10527042, PMID 10853813, PMID 10979878, PMID 11076832, PMID 11400186, PMID 11724917, PMID 12498954, PMID 12904089, PMID 15175402, PMID 15345186, PMID 15645531, PMID 15779234, PMID 15923132, PMID 16025231, PMID 16278898, PMID 16442563, PMID 16715205, PMID 16837857, PMID 17190953, PMID 17482283, PMID 18079166, PMID 18256395, PMID 18349024, PMID 18752978, PMID 19018276, PMID 19194885, PMID 20146689, PMID 20188504, PMID 20363190, PMID 20402743, PMID 20497190, PMID 20652413, PMID 20846908, PMID 20887968, PMID 20976736, PMID 21045744, PMID 21421334, PMID 21538520, PMID 21554495, PMID 21571570, PMID 21644059, PMID 21700495, PMID 21791473, PMID 21802993
2023 (2), 1RF1AG074608-01 (1), K01AG047279 (1), P01AG066597 (1), P30AG072979 (1), R01AG059008 (1), R01AG073161 (1), R01AG075404 (1), R01AG078457 (1), R01AG087140 (1), R01AG092949 (1), R01DC014475 (1), R01NR016037 (1), R37HD043341 (1), RF1NS145263 (1)