8 completed, 5 unknown, 2 recruiting, 1 not yet recruiting. 9 Not applicable, 4 Phase 2, 3 Phase 1, 2 Phase 3, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 9 | Completed 5, Recruiting 2, Unknown 2 |
| Phase 2 | 4 | Unknown 2, Not yet recruiting 1, Terminated 1 |
| Phase 1 | 3 | Completed 2, Unknown 1 |
| Phase 3 | 2 | Unknown 2 |
| Early Phase 1 | 1 | Completed 1 |
Follow Frankincense: new trials by email Literature Review of Frankincense trials Research Report on Frankincense
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Boswellia for Urinary Toxicity in Prostate Cancer Radiotherapy Boswellia serrata extract - Prostate Cancer | Phase 2 | Not yet recruiting | Brigham and Women's Hospital | 20 | 2026-10-01 | 2026-10-09 |
| Topical Boswellia Serrata 2% to Prevent Radiation Dermatitis in Head and Neck Cancer Boswellia serrata 2% topical cream - Head and Neck Neoplasms, Radiodermatitis | Not applicable | Recruiting | Youssef Hashem Hafez | 60 | 2026-08-18 | 2026-08-21 |
| Effect of Boswellia Serrata on Pain Intensity, Central and Peripheral Sensitization, and Pain Modulation in Healthy Volunteers Boswellia serrata extract, Placebo - Chronic Pain, Central Sensitisation | Not applicable | Recruiting | Medical University of Graz | 12 | 2025-09-01 | 2025-09-24 |
| Effect of Boswellia Sacra as an Intracanal Medicament on Postoperative Pain Intensity and Bacterial Load Reduction Boswellia Sacra - Intervention | Not applicable | Unknown | Cairo University | 45 | 2024-05-01 | 2024-04-12 |
| Effects of Rosa Damascena and Frankincense Essential Oils in Labor Rosa damascena oil - Labor Pain | Not applicable | Unknown | Balikesir University | 39 | 2024-01-21 | 2025-06-18 |
| Investigate"Clinically" the Effectiveness of Boswellia Based Intracanal Medication Compared to Calcium Hydroxide Ca(OH)2 and Ledermix on the Levels of Bacteria and Inflammatory Cytokines in Root Canals and Periradicular Tissues of Teeth With Apical Periodontitis Calcium hydroxide, Leddermix, Boswellia - Microbial Colonization | Phase 2 / Phase 3 | Unknown | Mansoura University | 36 | 2022-06-01 | 2024-06-20 |
| A Study of the Feasibility of Using the Dietary Supplement "ARTNEO" in Patients With Osteoathritis undenaturated collagen type II, methylsulfonylmethane, boswellia serrata, vitamin D3 (cholecalciferol), vitamin C (ARTNEO), Placebo - Osteoarthritis, Knee, Osteoarthritis | Not applicable | Completed | NPO Petrovax | 212 | 2022-05-31 | 2024-08-02 |
| Effect of Hyaluronic Acid Oral Supplementation on Sexual and Urinary Symptoms of Women With Recurrent Urinary Tract Infections HA 100 mg, CS 400 mg, N-Acetylglucosamine 200 mg and vitamin C 80 mg + cranberry, D-mannose, propolis extract, tumeric and Boswellia, cranberry, D-mannose, propolis extract, tumeric and Boswellia - Urinary Tract Infections, Recurrent | Not applicable | Completed | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 50 | 2022-03-01 | 2024-02-20 |
| Antibacterial and Anti-biofilm Activity of Frankincense Extract Against Porphyromonas Gingivalis Frankincense Extract - Periodontal Diseases | Phase 1 | Completed | Tanta University | 30 | 2021-01-15 | 2021-07-22 |
| Complementary Intervention for COVID-19 Licorice extract - COVID-19 | Not applicable | Completed | Egyptian Biomedical Research Network | 50 | 2020-01-01 | 2022-04-01 |
| Treatment of Renal Stones With Frankincense (Luban) AKBA-Incense (3-acetyl-11-keto-ß-boswellic acid), Potassium Sodium Hydrogen Citrate - Renal Stones | Phase 1 / Phase 2 | Unknown | Sultan Qaboos University | 100 | 2019-09-01 | 2019-04-29 |
| Massage With Frankincense and Myrrh Oil in Treating Chronic Low Back Pain massage with frankincense and myyrh essential oil, massage with carrier oil - Low Back Pain | Not applicable | Completed | TC Erciyes University | 91 | 2019-07-01 | 2020-07-31 |
| A "Window Trial" on Boswellia for Breast Cancer Primary Tumors Boswellia - Breast Cancer | Phase 1 | Completed | Medical University of South Carolina | 46 | 2017-08-31 | 2024-04-30 |
| Effects of Botanical Microglia Modulators in Gulf War Illness Boswellia Serrata, Curcumin, Epimedium - Gulf War Illness | Not applicable | Completed | University of Alabama at Birmingham | 36 | 2016-07-01 | 2025-01-24 |
| Acupoint Application in Patients With Stable Angina Pectoris (AASAP) Herbal plaster ( styrax, borneol, frankincense, santalum,trichosanthes kirilowii Maxim, allium macrostemon Bunge, leech), acupoint, Aspirin: 100mg qd; Metoprolol：25mg bid; Ramipril:5mg qd; Atorvastatin:20mg qn. - Stable Angina Pectoris | Early Phase 1 | Completed | Chengdu University of Traditional Chinese Medicine | 200 | 2012-10-01 | 2020-02-17 |
| Efficacy of Myalgesin™ to Support Joint Function in Patients With Knee Osteoarthritis Myalgesin™ (celery seed extract, Boswellia serrata extract, Phellodendron extract) - Osteoarthritis | Phase 3 | Unknown | ProThera, Inc. | 110 | 2006-05-01 | 2007-12-28 |
| Dietary, Herbal and Alternative Medicine in Glioblastoma Multiforme Boswellia serrata extract, cyanocobalamin - Brain and Central Nervous System Tumors, Cerebral Edema | Phase 2 | Terminated | Ali Altunkaya | 12 | 2004-09-01 | 2019-04-30 |
Chronic Pain (2) · Osteoarthritis (2) · Angina, Stable (1) · Astrocytoma (1) · Brain Edema (1) · Breast Neoplasms (1) · COVID-19 (1) · Central Nervous System Neoplasms (1) · Communicable Diseases (1) · Glioblastoma (1) · Gliosarcoma (1) · Head and Neck Neoplasms (1) · Kidney Calculi (1) · Labor Pain (1) · Low Back Pain (1)
Ali Altunkaya (1) · Balikesir University (1) · Brigham and Women's Hospital (1) · Cairo University (1) · Chengdu University of Traditional Chinese Medicine (1) · Egyptian Biomedical Research Network (1) · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico (1) · Mansoura University (1) · Medical University of Graz (1) · Medical University of South Carolina (1) · NPO Petrovax (1) · ProThera, Inc. (1) · Sultan Qaboos University (1) · TC Erciyes University (1) · Tanta University (1)
Egypt (5) · United States (4) · Turkey (Türkiye) (2) · Austria (1) · China (1) · Italy (1) · Oman (1) · Russia (1)
Adel A. Gomaa, Ph.D. (1) · Alaa A. El.Baz (1) · Amany Badr, Professor (1) · Fanrong Liang (1) · Glen Stevens, DO, PhD (1) · Jarred W Younger, PhD (1) · Ludmila Alekseeva, MD (1) · Nancy Klauber-DeMore, MD, FACS (1) · Stuart I Erner, MD (1) · Youssry RM Elhawary, Professor (1)
PMID 25250055, PMID 33192504, PMID 33802272, PMID 33802381, PMID 33915962, PMID 34387828, PMID 35233748, PMID 37121835, PMID 38721680
R21CA107277 (1)