16 completed, 3 terminated, 1 active not recruiting, 1 withdrawn. 7 Not applicable, 4 Phase 4, 3 Phase 1, 3 Phase 2, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 6, Active not recruiting 1 |
| Phase 4 | 4 | Terminated 3, Withdrawn 1 |
| Phase 1 | 3 | Completed 3 |
| Phase 2 | 3 | Completed 3 |
| Phase 3 | 3 | Completed 3 |
Follow Migraine Headaches: new trials by email Literature Review of Migraine Headaches trials Research Report on Migraine Headaches
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Yogabased Movements for Primary Headaches (Migraine and/or Cluster Headache) - YOURHEAD - a Pilot Study Intervention yogabased movements - Cluster Headache - Episodic and Chronic, Migraine Headache | Not applicable | Active not recruiting | Karolinska Institutet | 20 | 2026-01-01 | 2026-09-23 |
| Acute Migraine Treatment in the ED With Gepants Rimegepant, Zavegepant - Migraine Headaches | Phase 4 | Terminated | Icahn School of Medicine at Mount Sinai | 9 | 2025-06-05 | 2026-04-29 |
| Effect of Breathing Techniques on Migraine Attacks and Severity breathing techniques - Migraine Headaches, Breathing Techniques | Not applicable | Completed | Dokuz Eylul University | 86 | 2022-11-01 | 2024-09-19 |
| The Efficacy of Neurofeedback Mindfulness in Migraine Management Neurofeedback mindfulness, Simple attention controlled task - Migraine Headaches | Not applicable | Completed | University of Saskatchewan | 101 | 2021-09-09 | 2024-04-02 |
| An Efficacy and Safety Study of DFN-02 (Sumatriptan Nasal Spray 10 mg) Sumatriptan 10 mg Nasal Spray, Sumatriptan Placebo Nasal Spray - Migraine Headaches | Phase 2 | Completed | Upsher-Smith Laboratories | 107 | 2016-07-11 | 2021-03-30 |
| Prospective, Multi-Center Evaluation of the Efficacy of Peripheral Trigger Decompression Surgery for Migraine Headaches Botulinum Toxin Type A, Surgery, Daily headache diary - Migraine Headaches | Not applicable | Completed | Ohio State University | 44 | 2015-09-01 | 2024-04-22 |
| Study to Determine the Efficacy and Safety of ELS-M11 in Acute Migraine ELS-M11, Placebo - Migraine Headaches | Phase 1 / Phase 2 | Completed | Achelios Therapeutics | 48 | 2014-03-01 | 2017-07-11 |
| Theramine® in the Prevention of Migraine Headache Theramine (medical food/old drug), Placebo (l-alanine) - Migraine Headaches | Phase 4 | Terminated | Vincent Martin, MD | 31 | 2013-11-01 | 2016-05-05 |
| Haldol/Diphenhydramine Versus Metoclopramide/Diphenhydramine for Treatment of Acute Headache in the ED: A RCT Haloperidol, Metoclopramide 10mg, Diphenhydramine - Migraine Headaches, Nausea | Phase 4 | Withdrawn | United States Naval Medical Center, Portsmouth | 2013-06-12 | 2025-07-29 | |
| The Utility of Telemedicine in the Management of Migraine Migraine Headaches | Completed | University of Texas Southwestern Medical Center | 45 | 2012-10-01 | 2019-10-25 | |
| Prochlorperazine Versus Acetaminophen, Aspirin, and Caffeine for the Treatment of Acute Migraine Aspirin, Acetaminophen, Caffeine pills, Prochlorperazine 10mg - Migraine Headaches | Phase 4 | Terminated | Albert Einstein Healthcare Network | 93 | 2010-11-01 | 2020-03-18 |
| Peer Mentorship: An Intervention To Promote Effective Pain Self-Management In Adolescents Mentorship - Irritable Bowel Syndrome (IBS), Functional Abdominal Pain | Not applicable | Completed | University of California, Los Angeles | 27 | 2009-12-01 | 2016-09-30 |
| Set Point Acupuncture for Migraines Using a Digital Assistant acupuncture - Migraine Headaches | Phase 1 | Completed | Memorial Medical Center | 50 | 2008-07-01 | 2013-07-12 |
| Patent Foramen Ovale in Children With Migraine Headaches Migraine Headaches | Completed | University of Utah | 109 | 2008-04-01 | 2017-12-26 | |
| Craniosacral Therapy in Migraine: A Feasibility Study Craniosacral therapy, Low strength static magnets - Migraine Headaches | Not applicable | Completed | University of North Carolina, Chapel Hill | 66 | 2006-09-01 | 2012-12-04 |
| PREMIUM Migraine Trial Sham Procedure, AMPLATZER PFO Occluder - Migraine Headaches, Patent Foramen Ovale | Not applicable | Completed | Abbott Medical Devices | 230 | 2006-01-01 | 2020-07-30 |
| To Evaluate the Safety and Efficacy of Trexima in the Acute Treatment of Migraine Headaches sumatriptan, naproxen sodium - Migraine Headaches | Phase 3 | Completed | POZEN | 1400 | 2004-08-01 | 2007-02-12 |
| To Evaluate the Safety and Efficacy of Trexima in the Acute Treatment of Migrane Headaches sumatriptan, naproxen sodium - Migraine Headaches | Phase 3 | Completed | POZEN | 1200 | 2004-07-01 | 2007-02-12 |
| The Safety Of Combo Formulation In The Treatment Of Multiple Episodes Of Acute Migraine Over 12 Months Sumatriptan and Naproxen sodium - Migraine Headaches | Phase 3 | Completed | POZEN | 500 | 2004-05-01 | 2007-03-01 |
| A Study of the Efficacy of RWJ-333369 in the Prevention of Migraine RWJ-333369 - Migraine Headaches | Phase 2 | Completed | SK Life Science, Inc. | 300 | 2002-03-01 | 2012-08-02 |
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Migraine Disorders (21) · Headache (4) · Epilepsy (2) · Agnosia (1) · Behavior (1) · Bronchiolitis Obliterans Syndrome (1) · Chest Pain (1) · Chronic Pain (1) · Cluster Headache (1) · Complex Regional Pain Syndromes (1) · Emergencies (1) · Facial Pain (1) · Fibromyalgia (1) · Foramen Ovale, Patent (1) · Headache Disorders (1)
Brain Diseases (21) · Central Nervous System Diseases (21) · Headache Disorders, Primary (21) · Nervous System Diseases (21) · Headache Disorders (20) · Pathological Conditions, Signs and Symptoms (9) · Neurologic Manifestations (8) · Signs and Symptoms (8) · Pain (5) · Cardiovascular Diseases (2) · Neurobehavioral Manifestations (2) · Aberrant Motor Behavior in Dementia (1) · Autonomic Nervous System Diseases (1) · Behavior (1) · Behavioral Symptoms (1)
Sumatriptan (4) · Naproxen (3) · Acetaminophen (1) · Acupuncture Therapy (1) · Alanine (1) · Aspirin (1) · Botulinum Toxins, Type A (1) · Diphenhydramine (1) · Educational Status (1) · Haloperidol (1) · Ketoprofen (1) · Metoclopramide (1) · Nadolol (1) · Nasal Sprays (1) · Palliative Care (1)
POZEN (3) · Abbott Medical Devices (1) · Achelios Therapeutics (1) · Albert Einstein Healthcare Network (1) · Dokuz Eylul University (1) · Icahn School of Medicine at Mount Sinai (1) · Karolinska Institutet (1) · Memorial Medical Center (1) · Ohio State University (1) · SK Life Science, Inc. (1) · Sandoz (1) · United States Naval Medical Center, Portsmouth (1) · University of California, Los Angeles (1) · University of North Carolina, Chapel Hill (1) · University of Saskatchewan (1)
United States (17) · Canada (1) · Sweden (1) · Turkey (Türkiye) (1)
David Taylor (3) · Andrew Charles, MD (1) · Crist J. Frangakis, Ph.D. (1) · Deborah Friedman, MD (1) · James Bale, MD (1) · John Douglas Mann, MD (1) · Jonathan Schimmel (1) · Jonathan Tobis, M.D. (1) · Kenneth Deitch, DO (1) · Lonnie K. Zeltzer, MD (1) · LuAnn Minich, MD (1) · Matthew Gaffigan, MD (1) · Rachel McCandless, MD (1) · Sagar Munjal, MD (1)
PMID 17405970, PMID 10331688, PMID 11472723, PMID 11807151, PMID 15111681, PMID 16148260, PMID 16188533, PMID 16362702, PMID 16373630, PMID 16963692, PMID 1727198, PMID 17295330, PMID 17478165, PMID 17541126, PMID 17927647, PMID 18541041, PMID 19222595, PMID 21600053, PMID 29191325, PMID 29878341, PMID 30877622, PMID 31450969, PMID 6694427, PMID 6784664, PMID 7908596, PMID 9774749
R21AT002750 (1)