384 completed, 90 recruiting, 81 unknown, 67 terminated. 204 Phase 2, 193 Not applicable, 94 Phase 1, 86 Phase 3, 53 Phase 4.
Follow this condition Literature Review of Bronchiolitis Obliterans Syndrome trials Research Report on Bronchiolitis Obliterans Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Mindfulness Intervention to Reduce Patient Reported Symptoms in Patients With Chronic Graft-Versus-Host Disease Biospecimen Collection, Mindfulness Relaxation, Survey Administration - Chronic Graft Versus Host Disease, Hematopoietic and Lymphatic System Neoplasm | Not applicable | Recruiting | City of Hope Medical Center | 17 | 2027-03-01 | 2026-10-16 |
| A Preliminary Clinical Study on the Efficacy of Cyclophosphamide and Sirolimus Combined With VIC-1911 in Preventing Graft-versus-Host Disease After Haploidentical Stem Cell Transplantation in Children 1mg /kg VIC-1911 - GVHD (Acute or Chronic) | Phase 1 | Recruiting | Shanghai Jiao Tong University School of Medicine | 9 | 2026-09-28 | 2026-10-20 |
| A Study to Investigate the Efficacy and Safety of Belumosudil Compared With Best Available Therapy in Participants Aged 12 Years or Older With Chronic Graft-versus-host Disease Belumosudil, Best available therapy (BAT) - Chronic Graft Versus Host Disease | Phase 3 | Not yet recruiting | Sanofi | 356 | 2026-09-07 | 2026-09-15 |
| A Multicentre Randomised Controlled Trial Evaluating the Efficacy of the SMILE™ Module for Improving Short-term Periodontal Outcomes, Compliance, and Acceptability Among Clinical Dental Students SMILE Module, Conventional Toothbrushing Module - Gingivitis, Gingivitis; Chronic | Not applicable | Not yet recruiting | National University of Malaysia | 66 | 2026-09-01 | 2026-07-15 |
| Efficacy of Bee Venom Phonophoresis in Treating Chronic Sinusitis: Bee Venom Phonophoresis, Standard Care (oral decongestants + saline nasal irrigation) - Chronic Sinusitis, Acute Sinusitis | Not applicable | Not yet recruiting | Sinai University | 30 | 2026-08-15 | 2026-08-04 |
| A Study to Investigate Safety of Belumosudil in Participants Aged 12 Years and Above, With Chronic Graft-versus-host Disease (cGVHD) Belumosudil - Chronic Graft Versus Host Disease | Phase 4 | Not yet recruiting | Sanofi | 26 | 2026-08-10 | 2026-05-12 |
| Study to Compare the Plasma Concentration of Belumosudil Given as an Oral Suspension and as a Tablet to Healthy Adult Male Participants Belumosudil - Chronic Graft Versus Host Disease | Phase 1 | Not yet recruiting | Sanofi | 58 | 2026-08-06 | 2026-07-24 |
| Mechanisms and Targeted Therapy of Airway Basal Cell Dysfunction in Bronchiolitis Obliterans Syndrome Bronchoscopic brushing, Single - cell cloning, Cell function identification - Bronchiolitis Obliterans Syndrome (BOS) | Not applicable | Withdrawn | Haikou Affiliated Hospital of Central South University Xiangya School of Medicine | 2026-07-26 | 2026-07-29 | |
| AMPLIFI: Adaptive Modulation of Plasticity Through Lactate and Fitness Interventions High intensity cycling, Low-intensity cycling, Health education session - Stroke, Chronic, Aging | Not applicable | Active not recruiting | University of Alabama at Birmingham | 48 | 2026-07-15 | 2026-07-17 |
| A Clinical Study Evaluating the Pharmacokinetic Characteristics and Safety of AHB-137 Injection in Participants With Mild to Moderate Liver Dysfunction and Those With Normal Liver Function. AHB-137 injection - Chronic Hepatitis B | Phase 1 | Recruiting | Ausper Biopharma Co., Ltd. | 32 | 2026-07-09 | 2026-07-29 |
| Effects of Using Miswak in Addition to Oral Hygiene Products in Patients With Gingivitis Miswak, Toothpaste - Gingivitis; Chronic | Not yet recruiting | Mustafa Kemal University | 36 | 2026-07-04 | 2026-07-08 | |
| Evaluation of the Short-term Effectiveness of Spinal Manipulation to Treat Acute and Subacute Low Back Pain. Spinal or peripheral manipulation of the lower back to treat lower back pain - Back Pain Lower Back Chronic | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire de Nīmes | 416 | 2026-07-01 | 2026-05-29 |
| Efficacy of an Anti-TSLP Monoclonal Antibody in the Management of Chronic Bronchial Disease Induced by Bronchiolitis Obliterans Syndrome in Allogeneic Hematopoietic Stem Cells Transplantation Recipients Tezepelumab - Bronchiolitis Obliterans Syndrome (BOS), HSCT | Phase 2 | Recruiting | Hopital Foch | 36 | 2026-06-24 | 2026-08-18 |
| Study of AHB-171 in Chronic Hepatitis B Participants AHB-171 Injection - Hepatitis B, Chronic (CHB) | Phase 2 | Recruiting | Ausper Biopharma Co., Ltd. | 138 | 2026-06-24 | 2026-07-21 |
| Anrikefon vs Nalfurafine for Sleep Quality in Hemodialysis Patients With CKD-aP Anrikefon, Nalfurafine - Pruritus Chronic, Kidney Diseases, Chronic | Phase 4 | Recruiting | Zhujiang Hospital | 50 | 2026-06-22 | 2026-08-25 |
| Ex Vivo-Expanded Regulatory T Cells Plus Low-Dose Interleukin-2 for Steroid-Refractory Chronic GVHD EVE-Treg - Graft Versus Host Disease (cGvHD) | Phase 1 | Recruiting | Leslie Kean | 21 | 2026-05-29 | 2026-07-23 |
| Shortwave Infrared Surgical Imaging Device Study Observational study of SWIR imaging device in surgery - Cholecystitis, Cholecystitis, Chronic | Enrolling by invitation | Cision Vision, Inc. | 50 | 2026-05-29 | 2026-08-04 | |
| A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256) INCA034176, Best available Treatment (BAT) - Chronic Graft-versus-host-disease | Phase 2 | Recruiting | Incyte Corporation | 60 | 2026-05-20 | 2026-10-09 |
| Dental Cleaning to Prevent Chronic Graft-Versus-Host Disease Dental Cleaning, Dental Plaque sampling - Chronic Graft Versus Host Disease, Acute Graft Versus Host Disease | Not applicable | Recruiting | Fred Hutchinson Cancer Center | 45 | 2026-05-12 | 2026-10-21 |
| Yogabased Movements for Primary Headaches (Migraine and/or Cluster Headache) - YOURHEAD Intervention yoga based exercises - Cluster Headache - Episodic and Chronic, Migraine Headache | Not applicable | Recruiting | Karolinska Institutet | 80 | 2026-05-01 | 2026-09-23 |
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Pain (51) · Graft vs Host Disease (46) · Low Back Pain (43) · Leukemia (41) · Hepatitis C (22) · Lymphoma, Follicular (20) · Stroke (20) · Leukemia, Lymphocytic, Chronic, B-Cell (19) · Bronchiolitis Obliterans (18) · Motor Activity (18) · Cholecystitis (17) · Hematologic Neoplasms (17) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (17) · Sinusitis (17)
Lung Diseases, Obstructive (702) · Organizing Pneumonia (702) · Bronchial Diseases (701) · Bronchiolitis (701) · Lung Diseases (700) · Respiratory Tract Diseases (700) · Bronchitis (699) · Immune System Diseases (698) · Bronchiolitis Obliterans (685) · Graft vs Host Disease (657) · Pathological Conditions, Signs and Symptoms (299) · Signs and Symptoms (166) · Pathologic Processes (143) · Neurologic Manifestations (137) · Disease Attributes (108)
ibrutinib (15) · belumosudil (14) · Prednisone (12) · Rituximab (12) · Mycophenolic Acid (11) · Sirolimus (11) · ruxolitinib (11) · Tacrolimus (10) · axatilimab (10) · Photopheresis (9) · Imatinib Mesylate (8) · Azithromycin (7) · Cyclophosphamide (7) · Cyclosporine (7) · KD025 (7)
Novartis Pharmaceuticals (17) · Hoffmann-La Roche (12) · Dana-Farber Cancer Institute (11) · Fred Hutchinson Cancer Center (11) · Incyte Corporation (11) · National Cancer Institute (NCI) (10) · AstraZeneca (9) · Pfizer (9) · Gilead Sciences (8) · M.D. Anderson Cancer Center (7) · Assistance Publique - Hôpitaux de Paris (6) · Sanofi (6) · Cairo University (5) · Foundation for Liver Research (5) · Karolinska Institutet (5)
United States (293) · Canada (67) · France (67) · Germany (62) · Spain (59) · United Kingdom (59) · Italy (52) · China (51) · Belgium (45) · Australia (33) · Netherlands (32) · Poland (32) · Turkey (Türkiye) (31) · South Korea (29) · Russia (25)
Stephanie Lee (5) · Amandeep Salhotra (3) · Esther Garcia, MD (3) · John Koreth, MBBS, DPhil (3) · Aldo T Iacono, MD (2)
PMID 32816215, PMID 20965785, PMID 23861248, PMID 24432712, PMID 25287629, PMID 26149717, PMID 28396102, PMID 31260802, PMID 34265047, PMID 34433773, PMID 34773261, PMID 35235189, PMID 36440464, PMID 36791280, PMID 38696034, PMID 39704205, PMID 10387937, PMID 10619108, PMID 10845940, PMID 10997973, PMID 11172169, PMID 11222360, PMID 11509929, PMID 11756187, PMID 11784274, PMID 11981005, PMID 12070007, PMID 12095178, PMID 12359244, PMID 12364304, PMID 12444880, PMID 12931119, PMID 14512314, PMID 15142114, PMID 15251978, PMID 15292060, PMID 15613541, PMID 15621359, PMID 15772908, PMID 16046530, PMID 16186460, PMID 16186597, PMID 16239908, PMID 16326235, PMID 16407509, PMID 16446108, PMID 16551963, PMID 16788100, PMID 16946302, PMID 17035671
2015 (6), 2014 (5), 2016 (5), 2009 (4), 2018 (4), 2019 (4), P30CA015704 (4), 2017 (3), 2023 (2), 2025 (2), P30CA033572 (2), R01AT007987 (2), U01HL069294 (2), 1UH2DK104655-01 (1), 2005 (1)