22 recruiting. 22 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 22 | Recruiting 22 |
Follow Ischemic Stroke: new trials by email Literature Review of Ischemic Stroke trials Research Report on Ischemic Stroke
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| NeuroAiD Patient-Reported Outcomes in Patients With Mild to Moderate Ischemic Stroke MLC901, Standard treatment for acute ischemic stroke - Stroke, Stroke, Acute Ischemic | Phase 4 | Recruiting | EVD Pharmacy and Medical Company Limited | 80 | 2026-09-10 | 2026-10-20 |
| Comparing the Safety and Efficacy of Apixaban and Rivaroxaban Apixaban, Rivaroxaban - Atrial Fibrillation | Phase 4 | Recruiting | VA Office of Research and Development | 10000 | 2026-06-01 | 2026-09-23 |
| Safety and Efficacy of Adjunctive GM1 to Mechanical Thrombectomy for Acute Anterior Circulation Large Vessel Occlusion Intravenous GM1 Therapy, Placebo Therapy - Stroke, Acute Ischemic Stroke | Phase 4 | Recruiting | Xuanwu Hospital, Beijing | 868 | 2026-05-14 | 2026-06-24 |
| SUMMIT RISE Study of Acute Ischemic Stroke Patients Route 92 Medical Reperfusion Systems - Acute Ischemic Stroke | Phase 4 | Recruiting | Route 92 Medical, Inc. | 500 | 2026-02-12 | 2026-02-27 |
| Tenecteplase Before Interhospital Transfer in Acute Basilar Artery Occlusion at 4.5 to 24 Hours Tenecteplase thrombolysis - Acute Ischemic Stroke, Basilar Artery Occlusion | Phase 4 | Recruiting | Xuanwu Hospital, Beijing | 316 | 2026-01-20 | 2026-03-19 |
| Intravenous Thrombolysis Combined With Tirofiban in Acute Ischemic Stroke Tirofiban, Placebo (0.9% normal saline) - Acute Ischemic Stroke | Phase 4 | Recruiting | Beijing Anzhen Hospital | 976 | 2025-11-11 | 2025-12-23 |
| Mexidol® Safety and Efficacy in Treatment of Hyperacute and Acute Ischemic Stroke Mexidol, Glycine - Ischemic Stroke | Phase 4 | Recruiting | Pharmasoft | 120 | 2025-11-04 | 2026-05-13 |
| Single-stage Pulmonary Vein Isolation Combined With Percutaneous Left Atrial Appendage Occluder Implantation in Patients With Recent Onset Ischemic Stroke and Atrial Fibrillation PVI + LAAO, single stage, LAAO, NOAC - Ischemic Stroke, Atrial Fibrillation | Phase 4 | Recruiting | Medical University of Silesia | 240 | 2025-10-31 | 2026-04-13 |
| Lacunar Stroke hyperAcute Clinical Utilization of Novel Approach Regimens: Rt-PA vs. DAPT Randomised Clinical Trial rt-PA, DAPT - Lacunar Stroke, Stroke | Phase 4 | Recruiting | Nippon Medical School | 500 | 2025-08-01 | 2026-08-04 |
| Stroke Prevention In Ischemic Stroke With Covert Atrial Fibrillation Apixaban, Aspirin - Stroke, Ischemic Stroke | Phase 4 | Recruiting | Assistance Publique - Hôpitaux de Paris | 1148 | 2025-06-18 | 2026-06-05 |
| Safety and Efficacy of Intravenous Thrombolysis in Patients With Ischemic Stroke and Direct Oral Anticoagulants Intake Tenecteplase or Alteplase - Ischemic Stroke | Phase 4 | Recruiting | Insel Gruppe AG, University Hospital Bern | 906 | 2025-03-14 | 2026-09-30 |
| Effect of Specific Mode Electroacupuncture Stimulation Combined with NGF on Dysphagia After Ischaemic Stroke: a Pilot Randomized Controlled Trial Nerver growth factor (NGF) injection, Placebo injection, EA intervention - Ischemic Stroke, Dysphagia | Phase 4 | Recruiting | The Third Affiliated hospital of Zhejiang Chinese Medical University | 144 | 2024-12-01 | 2024-12-17 |
| China Stroke Primary Prevention Trial 2 for Participants With H-type Hypertension and MTHFR 677 CC/CT Genotype (CSPPT2-CC/CT) Amlodipine besylate, Amlodipine besylate and folic acid, Amlodipine placebos - Hypertension, MTHFR 677 CC or CT Genotype | Phase 4 | Recruiting | Shenzhen Ausa Pharmed Co.,Ltd | 32000 | 2024-08-22 | 2025-02-26 |
| China Stroke Primary Prevention Trial 2 for Participants With Hypertension and MTHFR 677 TT Genotype Amlodipine besylate, Amlodipine besylate And Folic Acid, 5-methyltetrahydrofolate (5-MTHF) - Hypertension, MTHFR 677 TT Genotype | Phase 4 | Recruiting | Shenzhen Ausa Pharmed Co.,Ltd | 24000 | 2024-08-22 | 2025-02-26 |
| Efficacy and Safety Study of Ultra-early Mobile Stroke Unit Neuroprotection Combined With Revascularization for Acute Ischemic Stroke (EXCELLENT) Intravenous thrombolysis + edaravone, IV thrombolysis + placebo (control group) - Ischemic Stroke | Phase 4 | Recruiting | Ruijun Ji | 300 | 2024-08-01 | 2025-08-12 |
| Atorvastatin Pretreatment in Cerebrovascular Events (APICES) After Flow Diverter Implantation Atorvastatin 20mg - Cerebrovascular Event, Stent Stenosis | Phase 4 | Recruiting | Duan Chuanzhi | 354 | 2024-07-30 | 2026-03-03 |
| Effect of Postoperative Prolonged Sedation With Dexmedetomidine After Successful Reperfusion With EVT on Long-term Prognosis in Patients With AIS (PPDET) Dexmedetomidine prolonged sedation, 0.9% saline - Acute Ischemic Stroke | Phase 4 | Recruiting | Beijing Chao Yang Hospital | 368 | 2024-03-01 | 2023-12-20 |
| Tenecteplase for Acute Ischemic Stroke Within 4.5 to 6 Hours of Onset (EXIT-BT2) Tenecteplase - Stroke, Ischemic | Phase 4 | Recruiting | General Hospital of Shenyang Military Region | 1440 | 2024-02-01 | 2026-09-10 |
| the Predictors of Hemorrhagic Transformation Subtypes in Acute Embolic Stroke Patients Alteplase - Ischemic Stroke, Alteplase Adverse Reaction | Phase 4 | Recruiting | Kafrelsheikh University | 716 | 2022-07-01 | 2024-10-29 |
| The Role of Circadian Factors in Regulation of Neuroplasticity in Ischemic Stroke (Interventional) Blue light exposure + Melatonin treatment, Melatonin treatment, Blue light exposure - Ischemic Stroke, Acute, Sleep Disorders, Circadian Rhythm | Phase 4 | Recruiting | Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health | 80 | 2022-03-01 | 2025-08-08 |
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Stroke (7) · Atrial Fibrillation (3) · Cerebral Infarction (2) · Hypertension (2) · Brain Death (1) · Deglutition Disorders (1) · Hemorrhage (1) · Hemorrhagic Stroke (1) · Intracranial Aneurysm (1) · Intracranial Arteriosclerosis (1) · Myocardial Infarction (1) · Sleep Disorders, Circadian Rhythm (1) · Stroke, Lacunar (1)
Brain Diseases (22) · Cardiovascular Diseases (22) · Central Nervous System Diseases (22) · Cerebrovascular Disorders (22) · Nervous System Diseases (22) · Vascular Diseases (22) · Stroke (15) · Pathologic Processes (7) · Pathological Conditions, Signs and Symptoms (7) · Heart Diseases (4) · Infarction (4) · Ischemia (4) · Necrosis (4) · Arrhythmias, Cardiac (3) · Brain Infarction (3)
Amlodipine (2) · Atorvastatin (2) · Folic Acid (2) · Rivaroxaban (2) · Saline Solution (2) · Tenecteplase (2) · Tissue Plasminogen Activator (2) · apixaban (2) · 5-methyltetrahydrofolate (1) · Aspirin (1) · Control Groups (1) · Dabigatran (1) · Edaravone (1) · Fibrinolytic Agents (1) · Glycine (1)
General Hospital of Shenyang Military Region (2) · Shenzhen Ausa Pharmed Co.,Ltd (2) · Xuanwu Hospital, Beijing (2) · Assistance Publique - Hôpitaux de Paris (1) · Beijing Anzhen Hospital (1) · Beijing Chao Yang Hospital (1) · Duan Chuanzhi (1) · EVD Pharmacy and Medical Company Limited (1) · Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health (1) · Insel Gruppe AG, University Hospital Bern (1) · Kafrelsheikh University (1) · Medical University of Silesia (1) · Nippon Medical School (1) · Pharmasoft (1) · Route 92 Medical, Inc. (1)
China (12) · France (2) · Russia (2) · United States (2) · Austria (1) · Belgium (1) · Canada (1) · Egypt (1) · Finland (1) · Germany (1) · Greece (1) · Japan (1) · Netherlands (1) · Norway (1) · Poland (1)
Cara N Pellegrini (1) · Chuanzhi Duan, MD (1) · Huisheng Chen, Doctor (1) · Jianping Li, MD, PhD (1) · Junwei Hao, MD (1) · Lyudmila Korostovtseva (1) · Maciej T. Wybraniec, MD, PhD, Professor (1) · Min Lou, PhD (1) · Thomas Meinel, MD, PhD (1) · William E. Boden, MD (1) · Yong Huo, MD, PhD (1) · Yuki Sakamoto (1)
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