170 completed, 80 unknown, 62 recruiting, 30 terminated. 124 Not applicable, 65 Phase 2, 47 Phase 3, 34 Phase 4, 19 Phase 1.
Follow Brain Infarction: new trials by email Literature Review of Brain Infarction trials Research Report on Brain Infarction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT) INTENT Neural Interface System - Tetraplegia/Tetraparesis, Amyotrophic Lateral Sclerosis (ALS) | Not applicable | Recruiting | Johns Hopkins University | 5 | 2027-01-01 | 2026-10-09 |
| The Safety and Efficacy of Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-ACI) in the Treatment of Acute Cerebral Infarction Allogeneic umbilical cord mesenchymal stem cells (SCLnow 19#), Aspirin Tablet - Cerebral Infarction | Phase 1 | Suspended | Sclnow Biotechnology Co., Ltd. | 40 | 2026-12-31 | 2026-04-23 |
| Human Umbilical Cord Mesenchymal Stem Cell Therapy (19#iSCLife®-CI) for Cerebral Infarction Patients in Convalescent Period. Allogeneic umbilical cord mesenchymal stem cell, Aspirin Enteric-coated Tablets & Atorvastatin Calcium - Cerebral Infarction | Phase 1 / Phase 2 | Suspended | Sclnow Biotechnology Co., Ltd. | 40 | 2026-12-31 | 2026-04-23 |
| Decompressive Craniectomy After Aneurysmal Subarachnoid Hemorrhage (DECIDE-SAH) Decompressive craniectomy - Aneurysmal Subarachnoid Hemorrhage | Not yet recruiting | University Hospital, Essen | 10000 | 2026-11-01 | 2026-10-14 | |
| Tenecteplase or Reteplase as Bridging Thrombolysis Before Thrombectomy in Acute Ischemic Cerebrovascular Events rhTNK-tPA (0.25mg/kg), Reteplase 10 Units (U) plus a second dose of reteplase 10 U, No thrombolysis (thrombectomy alone) - Acute Ischemic Stroke, Large Vessel Occlusion | Phase 3 | Recruiting | Yongjun Wang | 1440 | 2026-10-16 | 2026-10-22 |
| iBCI Optimization for Veterans With Paralysis Mobile neural decoding platform (mobile iBCI) - Spinal Cord Injury, Amyotrophic Lateral Sclerosis | Not applicable | Not yet recruiting | VA Office of Research and Development | 2 | 2026-10-02 | 2026-07-27 |
| Safely Quenching Complement in Stroke Survivors Pegcetacoplan Injection [Empaveli] - Acute Ischemic Stroke, Cerebral Infarction | Phase 1 | Not yet recruiting | Columbia University | 20 | 2026-10-01 | 2026-04-29 |
| Epidiolex Trial for Presymptomatic Treatment of Sturge-Weber Syndrome Epidiolex 100 mg/mL Oral Solution - Sturge - Weber Syndrome (SWS) | Phase 2 | Recruiting | Johns Hopkins University | 10 | 2026-09-17 | 2026-10-02 |
| Transcranial Doppler Evaluation After Endovascular Thrombectomy for Acute Ischemic Stroke (PRECISE-TCD) Transcranial Doppler (TCD) examination - Anterior Cerebral Artery Syndrome, Anterior Cerebral Artery Stroke | Not yet recruiting | Virginia Commonwealth University | 100 | 2026-09-01 | 2026-09-14 | |
| Stroke Cerebral Reorganization Pathways (SPECTRE) Clinical scores and functional MRI - Brain Diseases, Ischemic Stroke | Not applicable | Not yet recruiting | Rennes University Hospital | 30 | 2026-09-01 | 2026-04-02 |
| A Trial of Adacolumn on Cerebral Edema After Anterior Circulation Ischemic Stroke Adacolumn®, Standard Reperfusion Therapy, Standard Medical Management - Cerebral Edema, Ischemic Stroke, Acute | Not applicable | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 10 | 2026-08-10 | 2026-08-07 |
| Master Study Protocol for the Cohort of the Specialist Network Stroke (SN Stroke)(Stroke-CORE) Intracerebral Haemorrhage, Paediatric Stroke | Not yet recruiting | Charite University, Berlin, Germany | 12750 | 2026-07-27 | 2026-07-09 | |
| Large Language Models Versus Anesthesiologists for ASA Physical Status Classification Anesthesia, Preoperative Risk Prediction | Not yet recruiting | Marmara University Pendik Training and Research Hospital | 350 | 2026-07-21 | 2026-07-10 | |
| Early Identification and Diagnosis of BAD-related Stroke Multisource clinical-imaging artificial intelligence diagnostic assessment - Branch Atheromatous Disease, Acute Ischemic Stroke | Recruiting | Peking Union Medical College Hospital | 1602 | 2026-07-15 | 2026-07-09 | |
| Safety and Efficacy of Edaravone Dexborneol Sublingual Tablets for Blood-Brain Barrier Dysfunction in CADASIL Edaravone Dexborneol Sublingual Tablets - CADASIL | Phase 2 | Not yet recruiting | Huashan Hospital | 60 | 2026-07-01 | 2026-07-09 |
| Biological Collection of the Rare Diseases of the Brain and Eye Vessels Cohort - 2 Biocollection, Neurological evaluation and Biocollection - CADASIL, Cavernous Angioma | Not applicable | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 600 | 2026-06-30 | 2026-06-16 |
| HR-MRI-Directed Tirofiban Therapy for Late-Window Acute Ischemic Stroke (TIAN) Tirofiban, dual antiplatelet therapy - Stroke, Acute, Stroke, Ischemic | Phase 3 | Recruiting | Weifang Medical University | 458 | 2026-06-22 | 2026-06-25 |
| Intravenous Thrombolysis With Tenecteplase Plus Thrombectomy Versus Thrombectomy Alone In Patients With A Large Ischemic Stroke: A Multicenter Randomized Controlled Trial (IVT-ALL-IN) Intravenous administration, MT alone - Stroke | Phase 3 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 486 | 2026-06-15 | 2026-05-22 |
| Developing a Tailored Neuropsychological Rehabilitation for Sturge-Weber Syndrome Sturge - Weber Syndrome (SWS) | Recruiting | University of Roma La Sapienza | 40 | 2026-06-10 | 2026-06-17 | |
| Minocycline After Successful Endovascular Thrombectomy Recanalization in Acute Anterior Circulation Large Vessel Occlusion (ATTRACTION-MINOA) Minocycline hydrochloride capsule, Placebo capsules of Minocycline hydrochloride capsules - Acute Ischemic Stroke, Vessel Occlusion | Phase 2 / Phase 3 | Recruiting | Xiang Luo | 860 | 2026-05-21 | 2026-05-27 |
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Cerebral Infarction (206) · Stroke (168) · Ischemic Stroke (97) · Brain Ischemia (59) · Cerebrovascular Disorders (56) · Infarction, Middle Cerebral Artery (38) · Brain Diseases (35) · Vascular Diseases (34) · CADASIL (33) · Nervous System Diseases (29) · Central Nervous System Diseases (28) · Brain Stem Infarctions (27) · Cardiovascular Diseases (26) · Stroke, Lacunar (21)
Pathological Conditions, Signs and Symptoms (391) · Necrosis (390) · Pathologic Processes (387) · Infarction (385) · Ischemia (372) · Cardiovascular Diseases (365) · Central Nervous System Diseases (363) · Nervous System Diseases (362) · Vascular Diseases (357) · Brain Diseases (356) · Cerebrovascular Disorders (335) · Brain Ischemia (314) · Stroke (223) · Intracranial Arterial Diseases (89)
Aspirin (21) · Cilostazol (10) · Clopidogrel (9) · Transcranial Direct Current Stimulation (8) · Tenecteplase (5) · Tissue Plasminogen Activator (5) · Brain-Computer Interfaces (4) · Injections (4) · Methods (4) · Saline Solution (4) · 3-n-butylphthalide (3) · Acupuncture Therapy (3) · Ancrod (3) · Coronary Artery Bypass (3) · Exercise (3)
Assistance Publique - Hôpitaux de Paris (11) · University of British Columbia (7) · Beijing Tiantan Hospital (6) · Bispebjerg Hospital (4) · Johns Hopkins University (4) · Leigh R. Hochberg, MD, PhD. (4) · Mayo Clinic (4) · National Institute of Neurological Disorders and Stroke (NINDS) (4) · Second Affiliated Hospital, Zhejiang University, School of Medicine (4) · Tanabe Pharma Corporation (4) · Xuanwu Hospital, Beijing (4) · Asan Medical Center (3) · Capital Medical University (3) · Charite University, Berlin, Germany (3) · Children's Hospital of Fudan University (3)
China (87) · United States (66) · France (38) · South Korea (22) · Germany (21) · United Kingdom (19) · Canada (14) · Spain (14) · Japan (12) · Denmark (11) · Italy (10) · Taiwan (9) · Switzerland (8) · Australia (7) · Netherlands (7)
Ada Tang, PhD (2) · Adeline Vanderver, MD (2) · Alon Friedman, MD/PhD (2) · Brodie Sakakibara, PhD (2) · Debbie A Hebert, MSc(Kin) (2) · Gottfried Schlaug, MD, PhD (2) · Janice Eng, PhD (2) · Jeffrey Weiss, MD (2) · Marieke JH Wermer, MD PhD (2) · Mark Bayley, MD (2) · Nieto Luis, Master (2) · Shinichiro Uchiyama, MD (2) · Steven Levy, MD (2) · Warren Wasiewski, M.D. (2)
PMID 22163120, PMID 21899409, PMID 22068990, PMID 33175411, PMID 34184251, PMID 37652700, PMID 41508158, PMID 10356105, PMID 10499938, PMID 10811152, PMID 11944746, PMID 15035006, PMID 15364702, PMID 15370761, PMID 15837243, PMID 15843671, PMID 16282547, PMID 16282564, PMID 16336965, PMID 16386660, PMID 16433905, PMID 16490835, PMID 16763187, PMID 17126719, PMID 17494672, PMID 17622759, PMID 17916121, PMID 17939776, PMID 18029233, PMID 18388340, PMID 18456558, PMID 18462283, PMID 18468545, PMID 19321945, PMID 19430275, PMID 19570514, PMID 19673813, PMID 19727657, PMID 19829090, PMID 19834012, PMID 19900934, PMID 19933977, PMID 19938343, PMID 20075341, PMID 20145390, PMID 20386637, PMID 20446946, PMID 20456839, PMID 20505173, PMID 20833591
2016 (2), U01DC017844 (2), 1DP2DC021055 (1), 1RF1AG074608-01 (1), 2009 (1), 2015 (1), 2019 (1), I01RX003803 (1), K23HD049472 (1), P50NS044148 (1), P50NS044227 (1), P50NS044283 (1), R01AG057855 (1), R01DC008796 (1), R01DC009899 (1)