62 completed, 41 unknown, 22 recruiting, 17 not yet recruiting. 150 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 150 | Completed 62, Unknown 41, Recruiting 22, Not yet recruiting 17, Terminated 4, Active not recruiting 3, Enrolling by invitation 1 |
Follow Ischemic Stroke: new trials by email Literature Review of Ischemic Stroke trials Research Report on Ischemic Stroke
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Anti-inflammatory and Anti-thrombotic Therapy With colcHicine and Low Dose Rivaroxaban for Major Adverse Cardiovascular Events Reduction in Ischemic Stroke Rivaroxaban 2.5 Mg Oral Tablet, Colchicine 0.5 MG, Placebo Rivaroxaban - Ischemic Stroke | Phase 4 | Not yet recruiting | Brazilian Clinical Research Institute | 4500 | 2027-01-01 | 2026-10-30 |
| Lumbrokinase vs Placebo in Moderate-to-Severe Ischemic Stroke Lumbrokinase, Lumbrokinase Placebo - Ischemic Stroke, Acute | Phase 4 | Not yet recruiting | Xinqiao Hospital of Chongqing | 1196 | 2026-11-01 | 2026-08-13 |
| Oral Anticoagulation in Patients With Prior Deep Intracerebral Hemorrhage, Atrial Fibrillation, and Ischemic Stroke Apixaban, No Oral Anticoagulation Strategy - Intracerebral Hemorrhage, Atrial Fibrillation (AF) | Phase 4 | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 852 | 2026-10-26 | 2026-10-20 |
| Tirofiban Combined With Aspirin in Moderate Ischemic Stroke Tirofiban, Tirofiban-matching placebo - Ischemic Stroke, Acute | Phase 4 | Not yet recruiting | Xinqiao Hospital of Chongqing | 1168 | 2026-10-01 | 2026-08-12 |
| Prevention of Infection of the Respiratory Tract Through Application of Non-Invasive Methods of Secretion Suctioning airway clearance, subglottic secretion aspiration, Ceftriaxone 2 grams daily - Intubation Complication, Stroke, Ischemic | Phase 4 | Not yet recruiting | Hospital San Carlos, Madrid | 60 | 2026-09-15 | 2026-08-06 |
| NeuroAiD Patient-Reported Outcomes in Patients With Mild to Moderate Ischemic Stroke MLC901, Standard treatment for acute ischemic stroke - Stroke, Stroke, Acute Ischemic | Phase 4 | Recruiting | EVD Pharmacy and Medical Company Limited | 80 | 2026-09-10 | 2026-10-20 |
| TeleStroke-Guided Thrombolysis for Acute Ischemic Stroke in Oman alteplase or tenecteplase - Ischemic Stroke, Acute, Ischemic Stroke | Phase 4 | Not yet recruiting | Oman Ministry of Health | 200 | 2026-08-01 | 2026-07-22 |
| A Trial of Edaravone Dexborneol in Acute Ischemic Stroke With Active Malignancy edaravone dexborneol injection, Standard therapeutic protocol - Ischemic Stroke, Acute, Active Malignancies | Phase 4 | Not yet recruiting | Nanfang Hospital, Southern Medical University | 144 | 2026-08-01 | 2026-04-16 |
| Ciprofol vs Propofol for Hemodynamic Stability in Patients Having General Anesthesia for Endovascular Thrombectomy After Ischemic Stroke Ciprofol, Propofol - Hemodynamic Stability, Ischemic Strokes | Phase 4 | Not yet recruiting | RenJi Hospital | 124 | 2026-07-01 | 2026-07-10 |
| Sublingual Edaravone Dexborneol for Inter-hospital Transfer Acute Ischemic Stroke (SLEDAIS) Edaravone dexborneol sublingual tablet, Placebo - Acute Ischemic Stroke | Phase 4 | Not yet recruiting | Xinqiao Hospital of Chongqing | 1040 | 2026-07-01 | 2026-07-06 |
| Platelet Aggregation Function-Guided De-Escalation Antiplatelet Therapy in Patients With Acute Ischemic Stroke Clopidogrel, Aspirin - Ischemic Stroke, Transient Ischemic Attack | Phase 4 | Not yet recruiting | Sichuan Provincial People's Hospital | 3836 | 2026-06-01 | 2026-06-12 |
| Comparing the Safety and Efficacy of Apixaban and Rivaroxaban Apixaban, Rivaroxaban - Atrial Fibrillation | Phase 4 | Recruiting | VA Office of Research and Development | 10000 | 2026-06-01 | 2026-09-23 |
| Safety and Efficacy of Adjunctive GM1 to Mechanical Thrombectomy for Acute Anterior Circulation Large Vessel Occlusion Intravenous GM1 Therapy, Placebo Therapy - Stroke, Acute Ischemic Stroke | Phase 4 | Recruiting | Xuanwu Hospital, Beijing | 868 | 2026-05-14 | 2026-06-24 |
| Butylphthalide for Brain Edema After Endovascular Treatment Butylphthalide, Placebo - Acute Ischemic Stroke | Phase 4 | Not yet recruiting | Nanfang Hospital, Southern Medical University | 100 | 2026-04-01 | 2026-04-14 |
| ATILA Project: Aspirin Versus Tirofiban in Endovascular Treatment for Patients With Acute Ischemic Stroke Due to Tandem Lesion Tirofiban, Acetylsalicylic acid - Acute Ischemic Stroke | Phase 4 | Completed | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 240 | 2026-03-20 | 2026-04-03 |
| SUMMIT RISE Study of Acute Ischemic Stroke Patients Route 92 Medical Reperfusion Systems - Acute Ischemic Stroke | Phase 4 | Recruiting | Route 92 Medical, Inc. | 500 | 2026-02-12 | 2026-02-27 |
| Tenecteplase Before Interhospital Transfer in Acute Basilar Artery Occlusion at 4.5 to 24 Hours Tenecteplase thrombolysis - Acute Ischemic Stroke, Basilar Artery Occlusion | Phase 4 | Recruiting | Xuanwu Hospital, Beijing | 316 | 2026-01-20 | 2026-03-19 |
| Early Administration of PCSK9 Inhibitors After Thrombectomy for Atherosclerotic Acute Ischemic Stroke: A Randomized Controlled Trial Evolocumab(420 mg injections) - Acute Stroke | Phase 4 | Completed | The Affiliated Hospital of Xuzhou Medical University | 60 | 2025-12-20 | 2026-07-13 |
| A Study Testing How Well the Drug Extract of Ginkgo Biloba Leaves Tablets Works for People With Memory or Thinking Problems After a Stroke When Added to Standard Treatment Extract of Ginkgo Biloba Leaves Tablets 240 mg (2 x 40 mg, t.i.d.), Standard of care (SoC) Group - Ischemic Stroke Hospitalized, Impairment, Cognitive | Phase 4 | Active not recruiting | Dr. Willmar Schwabe GmbH & Co. KG | 400 | 2025-11-28 | 2026-10-30 |
| Intravenous Thrombolysis Combined With Tirofiban in Acute Ischemic Stroke Tirofiban, Placebo (0.9% normal saline) - Acute Ischemic Stroke | Phase 4 | Recruiting | Beijing Anzhen Hospital | 976 | 2025-11-11 | 2025-12-23 |
Showing 20 of 150. Sign in to see all of them.
Stroke (32) · Atrial Fibrillation (8) · Thrombosis (7) · Brain Ischemia (6) · Cerebral Infarction (4) · Hypertension (4) · Intracranial Arteriosclerosis (4) · Ischemic Attack, Transient (4) · Myocardial Infarction (4) · Aortic Valve Disease (3) · Cerebral Hemorrhage (3) · Cerebrovascular Disorders (3) · Embolic Stroke (3) · Hemorrhage (3)
Brain Diseases (150) · Central Nervous System Diseases (149) · Cardiovascular Diseases (148) · Nervous System Diseases (148) · Vascular Diseases (148) · Cerebrovascular Disorders (147) · Stroke (118) · Pathological Conditions, Signs and Symptoms (31) · Pathologic Processes (30) · Heart Diseases (14) · Infarction (10) · Ischemia (10) · Necrosis (10) · Arrhythmias, Cardiac (7) · Brain Ischemia (7)
Aspirin (21) · Clopidogrel (18) · Tissue Plasminogen Activator (10) · Atorvastatin (8) · Cilostazol (6) · Rosuvastatin Calcium (5) · Injections (4) · Saline Solution (4) · Tenecteplase (4) · cerebrolysin (4) · 3-n-butylphthalide (3) · Amlodipine (3) · Platelet Aggregation Inhibitors (3) · Probucol (3) · Rivaroxaban (3)
Xuanwu Hospital, Beijing (6) · General Hospital of Shenyang Military Region (5) · Beijing Tiantan Hospital (4) · Sichuan Provincial People's Hospital (4) · China Academy of Chinese Medical Sciences (3) · Dongzhimen Hospital, Beijing (3) · Kafrelsheikh University (3) · Second Affiliated Hospital, Zhejiang University, School of Medicine (3) · Xijing Hospital (3) · Xinqiao Hospital of Chongqing (3) · Ain Shams University (2) · Ajou University School of Medicine (2) · Asan Medical Center (2) · Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec (2) · First Affiliated Hospital, Sun Yat-Sen University (2)
China (68) · South Korea (12) · United States (11) · Canada (7) · Spain (7) · Austria (5) · Egypt (5) · Japan (5) · Russia (5) · France (4) · Germany (4) · Italy (4) · Belgium (3) · Greece (3) · Netherlands (3)
Jie Yang, doctor (2) · Junwei Hao, MD (2) · Ying Gao, MD (2) · Zhongming Qiu (2) · A H Li, MD (1) · Adem Az, Assoc. Prof. (1) · Andrey Avgustovich Belkin, Prof.,MD,PhD (1) · Arunodaya R Gujjar, MD, DM, FRCP (1) · Brian Buck, MD (1) · Byung-chul Lee, MD, PhD (1) · Cara N Pellegrini (1) · Carlo Cereda, Capo CLinica (1) · Carlos Morillo, MD (1) · Charlotte Rath, MD (1)
PMID 12221155, PMID 16731270, PMID 34515113, PMID 21869730, PMID 22230384, PMID 22880024, PMID 22897803, PMID 24957314, PMID 25771069, PMID 27834686, PMID 28527771, PMID 29030456, PMID 36446950, PMID 10634801, PMID 10639539, PMID 1135616, PMID 11498461, PMID 11786451, PMID 11897754, PMID 11937179, PMID 12045168, PMID 12135313, PMID 12493255, PMID 13678932, PMID 14581662, PMID 14656957, PMID 15232117, PMID 15879332, PMID 16176495, PMID 16448896, PMID 16476843, PMID 17179034, PMID 17253471, PMID 17337887, PMID 17437989, PMID 17448820, PMID 17485598, PMID 17510503, PMID 17515473, PMID 17698822, PMID 18268136, PMID 18757238, PMID 18815396, PMID 19336502, PMID 19380621, PMID 19628800, PMID 19696423, PMID 19762550, PMID 19817870, PMID 19850215
2015 (1), 2025 (1), 4UH3NS119702-02 (1), R01NS032525 (1)