13 completed, 3 unknown, 1 not yet recruiting, 1 recruiting. 14 Phase 1, 13 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 14 | Completed 10, Unknown 3, Withdrawn 1 |
| Phase 2 | 13 | Completed 10, Recruiting 1, Unknown 1, Withdrawn 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cultivated Limbal Epithelial Transplantation (CLET) for Limbal Stem Cell Deficiency (LSCD) Limbal Stem-cell Deficiency | Not yet recruiting | Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA | 30 | 2025-11-01 | 2025-05-16 | |
| Treatment of Lupus Nephritis With Allogeneic Mesenchymal Stem Cells Mesenchymal stem cells (MSC), Placebo - Lupus Nephritis, Lupus Erythematosus | Phase 2 | Recruiting | Red de Terapia Celular | 20 | 2022-12-27 | 2026-08-18 |
| Treatment of Severe COVID-19 Pneumonia With Allogeneic Mesenchymal Stem Cells Mesenchymal Stem Cells (MSCs), Placebo - COVID-19 Pneumonia | Phase 2 | Completed | Red de Terapia Celular | 24 | 2020-05-01 | 2024-02-02 |
| Clinical Trial of Use of Autologous Bone Marrow Stem Cells Seeded on Porous Tricalcium Phosphate Matrix and Demineralized Bone Matrix in Patients With Osteonecrosis MSC construct for Osteonecrosis - Osteonecrosis of Jaw | Phase 1 | Unknown | Red de Terapia Celular | 10 | 2015-09-01 | 2017-03-30 |
| Clinical Trial of Intravenous Infusion of Fucosylated Bone Marrow Mesenchyme Cells in Patients With Osteoporosis Fucosylated MSC for Osteoporosis - Osteoporosis, Spinal Fractures | Phase 1 | Completed | Red de Terapia Celular | 10 | 2015-09-01 | 2020-10-08 |
| Clinical Trial of Intravitreal Injection of Autologous Bone Marrow Stem Cells in Patients With Retinitis Pigmentosa Intravitreal injection of Autologous bone marrow Stem Cell, Subconjunctival injection of saline - Retinitis Pigmentosa | Phase 1 | Completed | Red de Terapia Celular | 8 | 2014-11-01 | 2017-03-30 |
| Intramuscular Infusion of Autologous Bone Marrow Stem Cells in Patients With Amyotrophic Lateral Sclerosis MNC (Mononuclear cells), Saline - ALS (Amyotrophic Lateral Sclerosis) | Phase 1 | Unknown | Red de Terapia Celular | 20 | 2014-11-01 | 2017-03-30 |
| Clinical Trial Phase I/II Prospective, Open Nonrandomized for Treatmen of Postoperative Air Leak After Lung Resection in High Risk Patients Through the Administration of Mesenchymal Autologous Cells Implantation of autologous mesenchymal stem cells (CSM) expanded "in vitro" and administered directly into the lung suture line - Postoperative Air Leaks in Risk Patients | Phase 1 / Phase 2 | Unknown | Red de Terapia Celular | 10 | 2013-12-01 | 2017-03-30 |
| Clinical Trial In The Treatment Of Allogeneic Post-Transplant Cytopenias With Sequential Infusion Of Allogeneic Mesenchymal Cells Expanded In Vitro Sequential infusion of allogeneic mesenchymal stem cells expanded "in vitro" - Cytopenia | Phase 2 | Completed | Red de Terapia Celular | 15 | 2013-10-01 | 2017-03-30 |
| Treatment of Degenerative Disc Disease With Allogenic Mesenchymal Stem Cells (MSV) Allogenic Mesenchymal Stromal Cells, Mepivacaine - Degenerative Disc Disease, Intervertebral Disc Disease | Phase 1 / Phase 2 | Completed | Red de Terapia Celular | 24 | 2013-06-21 | 2024-04-29 |
| Extracorporeal Photopheresis in Liver Transplantation. Phase II Clinical Trial in Safety and Efficacy in Patients With Gradual Decrease of Immunosuppression. Extracorporeal Photopheresis Procedure (FEC) - Liver Transplantation, Immunosuppression | Phase 1 / Phase 2 | Completed | Red de Terapia Celular | 10 | 2013-04-01 | 2017-03-30 |
| Use of the Amniotic Membrane in Large Wound Epithelialization Place amniotic membrane in large wounds, Obtaining and Cryopreservation of amniotic membrane, amniotic membrane - Wounds | Phase 1 | Completed | Red de Terapia Celular | 6 | 2012-07-01 | 2017-03-30 |
| PHASE II CLINICAL TRIAL Prospective, Open, Nonrandomized Treatment of Osteonecrosis of the Femoral Head by the Administration of Autologous Mesenchymal Stem Cells bone marrow aspirate - Osteonecrosis of the Femoral Head | Phase 2 | Completed | Red de Terapia Celular | 3 | 2012-07-01 | 2017-03-30 |
| Treatment of Knee Osteoarthritis With Allogenic Mesenchymal Stem Cells Allogenic mesenchymal stromal cells injection, Hyaluronic Acid - Osteoarthritis, Knee, Arthritis of Knee | Phase 1 / Phase 2 | Completed | Red de Terapia Celular | 30 | 2012-04-01 | 2015-10-16 |
| Safety Study of Stem Cell Transplant to Treat Limbus Insufficiency Syndrome Stem Cell with Amniotic Membrane Transplant - Limbus Corneae Insufficiency Syndrome | Phase 1 / Phase 2 | Completed | Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA | 27 | 2012-03-01 | 2015-01-08 |
| Lumbar Degenerative Disc Disease Treatment With Bone Marrow Autologous Mesenchymal Stem Cells (MSV) Autologous bone marrow mesenchymal stem cells - Degenerative Disc Disease | Phase 1 / Phase 2 | Withdrawn | Red de Terapia Celular | 2011-06-01 | 2015-05-12 | |
| Treatment Of Maxillary Bone Cysts With Autologous Bone Mesenchymal Stem Cells (MSV-H) MSV treatment - Maxillary Cyst, Bone Loss of Substance | Phase 1 / Phase 2 | Completed | Red de Terapia Celular | 11 | 2011-04-01 | 2017-04-27 |
| Treatment of Knee Osteoarthritis With Autologous Mesenchymal Stem Cells Autologous bone marrow mesenchymal stem cells (MSV) - Osteoarthritis, Knee, Knee Degenerative Disease | Phase 1 / Phase 2 | Completed | Red de Terapia Celular | 12 | 2010-05-01 | 2015-01-15 |
| Clinical Trial Based on the Use of Mesenchymal Stem Cells From Autologous Bone Marrow in Patients With Lumbar Intervertebral Degenerative Disc Disease Instrumented posterolateral arthrodesis - Intervertebral Disc Disease | Phase 1 / Phase 2 | Completed | Red de Terapia Celular | 15 | 2010-01-01 | 2017-06-02 |
Musculoskeletal Diseases (3) · Intervertebral Disc Degeneration (2) · Intervertebral disc disease (2) · Low Back Pain (2) · Osteoarthritis (2) · Osteoarthritis, Knee (2) · Amyotrophic Lateral Sclerosis (1) · Autoimmune Diseases (1) · COVID-19 (1) · Corneal Diseases (1) · Cytopenia (1) · Legg-Calve-Perthes Disease (1) · Limbal Stem Cell Deficiency (1) · Lupus Erythematosus, Systemic (1) · Lupus Nephritis (1)
Genes, mos (5) · Sodium Chloride (2) · Biological Dressings (1) · FEC protocol (1) · Hyaluronic Acid (1) · Mepivacaine (1) · Saline Solution (1)
Spain (18)
Ana Sanchez, MD, PhD (3) · Javier Garcia-Sancho, MD, PhD (2) · Julia Barbado, MD, PhD (2) · Luis Orozco, MD, PhD (2) · Rosa Conde, PhD (2) · Aurelio Vega, MD,PhD (1) · David C Noriega, MD, PhD (1) · FRancisco Ardura, MD, PhD (1)
PMID 30578758, PMID 21850186, PMID 22415951, PMID 23405945, PMID 23680930, PMID 23767776, PMID 23892486, PMID 24887752, PMID 25075515, PMID 25822648, PMID 26451369, PMID 26704459, PMID 27661661, PMID 27911610, PMID 28758321, PMID 29229365, PMID 30716697, PMID 30795797, PMID 32265627, PMID 37038216, PMID 37773479, PMID 37904229, PMID 42727576