293 completed. 293 Phase 1, 88 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 293 | Completed 293 |
| Phase 2 | 88 | Completed 88 |
Follow Inflammation: new trials by email Literature Review of Inflammation trials Research Report on Inflammation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Assess the Safety and Effects of Different Doses of an Investigational Drug, BAY 3389934, in Healthy Japanese Volunteers. BAY 3389934, Matching Placebo / Diluent - Sepsis Associated Disseminated Intravascular Coagulation (DIC) | Phase 1 | Completed | Bayer | 16 | 2025-09-22 | 2026-06-05 |
| Safety, Tolerability and Efficacy of GcMAF in Patients With Chronic Inflammatory Diseases GcMAF, Placebo Injection (Saline) - Inflammation | Phase 1 / Phase 2 | Completed | S.LAB (SOLOWAYS) | 120 | 2025-09-01 | 2025-12-16 |
| A Study to Investigate How AZD4144 Affects the Pharmacokinetics of Rosuvastatin in Healthy Participants AZD4144, Rosuvastatin - Healthy | Phase 1 | Completed | AstraZeneca | 12 | 2025-04-17 | 2025-06-18 |
| An Accessorised Prefilled Syringe to an Autoinjector Pharmacokinetic Bridging Study of Tozorakimab Tozorakimab, Autoinjector (AI) Device, Accessorised Prefilled Syringe (APFS) Device - Healthy Participants | Phase 1 | Completed | AstraZeneca | 254 | 2025-04-07 | 2025-12-02 |
| PET Study of PIPE-791 in Healthy Volunteers and Volunteers With PrMS and IPF PIPE-791 - Idiopathic Pulmonary Fibrosis (IPF), Idiopathic Pulmonary Fibrosis | Phase 1 | Completed | Contineum Therapeutics | 16 | 2024-12-09 | 2025-08-06 |
| A Study in Healthy Subjects to Assess the Safety and Tolerability of a 120-hour Continuous Infusion of M6229 M6229, Placebo - Healthy Subjects | Phase 1 | Completed | Matisse Pharmaceuticals | 15 | 2024-11-21 | 2025-12-16 |
| Role of Enteral Lactoferrin as an Adjuvant for Prevention of Sepsis Among Preterm Neonates Bovine Lactoferrin Supplement - Sepsis | Phase 1 | Completed | Zartash Sial Paeds Med | 180 | 2024-10-01 | 2026-03-18 |
| Effect of Bee Venom on T Regulatory Cells and Inflammation in Hemodialysis Patients: a Prospective Study Thesis Bee Venom (BV) - Hemodialysis, Inflammation | Phase 1 / Phase 2 | Completed | Mansoura University | 60 | 2024-06-01 | 2026-10-30 |
| Single and Multiple Ascending Oral Doses of Avenanthramide Avenanthramide, Placebo - Inflammation | Phase 1 / Phase 2 | Completed | Montreal Heart Institute | 92 | 2023-12-09 | 2026-04-20 |
| Improvement of Organ Function by Apigenin in Elderly Patients With Sepsis apigenin, sterilized water - Sepsis, Septic Shock | Phase 1 / Phase 2 | Completed | Zhujiang Hospital | 20 | 2023-09-01 | 2024-03-13 |
| Phase 1b MMV367 PK/PD and Safety in Healthy Adult Volunteers Experimentally Infected With Blood Stage P. Falciparum MMV367 3mg, P. falciparum IBSM infection, MMV367 5mg - Infections, Vector Borne Diseases | Phase 1 | Completed | Medicines for Malaria Venture | 12 | 2023-08-01 | 2025-12-10 |
| Aging and Reward System Response to Inflammation and Anxiety Study Endotoxin, Placebo - Anhedonia, Inflammation | Phase 1 | Completed | University of California, Los Angeles | 40 | 2023-03-29 | 2025-12-11 |
| Trial to Model Primary, Secondary, and Tertiary Dengue Using a Monovalent Vaccine rDEN3Δ30/31-7164 - Response To Dengue Exposure | Phase 1 | Completed | National Institutes of Health Clinical Center (CC) | 127 | 2023-03-07 | 2026-06-16 |
| Effect of Supplementation With Anthocyanins on Iron Metabolism in Female Swimmers Black chokeberry extract in capsules with 18% standardization of the anthocyanins content, Chokeberry fiber in capsules - Iron Deficiencies, Inflammation | Phase 1 / Phase 2 | Completed | Poznan University of Physical Education | 22 | 2023-03-01 | 2024-07-03 |
| Montmorency Cherry Supplementation, Sleep, and Inflammation Montmorency cherry supplement, Control - Insomnia Chronic, Inflammation | Phase 1 / Phase 2 | Completed | Michigan State University | 34 | 2023-02-18 | 2025-09-08 |
| Alirocumab in Patients with Sepsis Alirocumab, Placebo - Sepsis | Phase 1 | Completed | Jonathan Sevransky | 50 | 2023-01-04 | 2025-03-24 |
| Safety & PK of Single Doses of MT1980 MT1980, Placebo - Neuroinflammatory Response | Phase 1 | Completed | Monument Therapeutics Limited | 24 | 2022-06-01 | 2022-11-02 |
| Alleviation of Common Cold Symptoms Wintergreen Throat Spray and Aspirin Tablet, Aspirin Throat Spray and Placebo Tablet, Wintergreen Throat Spray and Placebo Tablet - Common Cold, Pharyngitis | Phase 1 | Completed | Applied Biological Laboratories Inc | 157 | 2022-05-25 | 2024-01-16 |
| Study Evaluating Safety, Tolerability, and Efficacy of Intravenous AP-SA02 in Subjects With S. Aureus Bacteremia AP-SA02, Placebo - Bacteremia, Staphylococcus Aureus | Phase 1 / Phase 2 | Completed | Armata Pharmaceuticals, Inc. | 56 | 2022-04-26 | 2026-03-23 |
| Intravenously Administered M6229 in Critically Ill Sepsis Patients M6229 - Sepsis, Septic Shock | Phase 1 | Completed | A.P.J. Vlaar | 10 | 2022-04-05 | 2025-02-11 |
Showing 20 of 293. Sign in to see all of them.
Sepsis (65) · Shock, Septic (29) · Arthritis, Rheumatoid (13) · Pain (9) · Malaria (8) · Parasitemia (8) · Cellulitis (7) · Endotoxemia (7) · Neuroinflammatory Diseases (7) · Asthma (6) · COVID-19 (6) · Critical Illness (6) · Cytokine Release Syndrome (6) · Diabetes Mellitus, Type 2 (6)
Pathological Conditions, Signs and Symptoms (293) · Pathologic Processes (289) · Infections (122) · Systemic Inflammatory Response Syndrome (103) · Shock (39) · Immune System Diseases (37) · Sepsis (36) · Respiratory Tract Diseases (35) · Skin and Connective Tissue Diseases (32) · Lung Diseases (31) · Nervous System Diseases (26) · Connective Tissue Diseases (24) · Cardiovascular Diseases (23) · Nutritional and Metabolic Diseases (23)
Lipopolysaccharides (6) · Aspirin (5) · Bronchoscopy (5) · Endotoxins (4) · Propofol (4) · Saline Solution (4) · Vitamin D (4) · Ascorbic Acid (3) · Diclofenac (3) · Fish Oils (3) · Melatonin (3) · Meropenem (3) · Micafungin (3) · Simvastatin (3) · Sodium Chloride (3)
GlaxoSmithKline (12) · National Institute of Allergy and Infectious Diseases (NIAID) (9) · Novo Nordisk A/S (7) · Radboud University Medical Center (7) · National Eye Institute (NEI) (5) · Bayer (4) · Emory University (4) · National Institute of Mental Health (NIMH) (4) · Sandoz (4) · University of Florida (4) · Indiana University (3) · King Abdul Aziz Specialist Hospital (3) · Lund University (3) · Mayo Clinic (3) · Medical University of Vienna (3)
United States (138) · Netherlands (21) · United Kingdom (19) · Germany (17) · Canada (12) · Australia (10) · Sweden (10) · China (8) · Belgium (5) · Mexico (5) · Austria (4) · Denmark (4) · Poland (4) · Brazil (3) · France (3)
Antonio Abbate, MD, PhD (3) · Paul D. Larsen, M.D. (3) · Yoghatama Cindya Zanzer, MSc (3) · Andrew D Luster, M.D., Ph.D. (2) · Anette Karlsen, MSc (2) · Iztok Potocnik, MD, MSC (2) · Joseph L Kuti, PharmD (2) · Mark Rickman, MD (2) · Martha M Eibl, MD (2)
PMID 25749867, PMID 29749279, PMID 10379020, PMID 15713907, PMID 16864730, PMID 17551901, PMID 17621602, PMID 17660031, PMID 17954801, PMID 18433844, PMID 18492739, PMID 18846389, PMID 19320056, PMID 19417610, PMID 20444270, PMID 20846424, PMID 20976161, PMID 21211004, PMID 21371308, PMID 21399490, PMID 21593349, PMID 21806852, PMID 22340260, PMID 22438931, PMID 22491916, PMID 22569355, PMID 22666474, PMID 23208880, PMID 23374652, PMID 23407260, PMID 23525414, PMID 23587979, PMID 23618062, PMID 23629714, PMID 23837842, PMID 23929949, PMID 24077434, PMID 24484547, PMID 24559067, PMID 24636395, PMID 25286986, PMID 25456364, PMID 25466700, PMID 25559834, PMID 25686304, PMID 25963404, PMID 25978169, PMID 26049730, PMID 26093876, PMID 26123683
2008 (4), 2019 (3), 2009 (2), 2016 (2), U19AI095261 (2), 1KL2RR031989-01 (1), 1RF1AG051514 (1), 2014 (1), K01AA026005 (1), K01AG072049 (1), K23HD060040 (1), K23HL105654 (1), K23NS087151 (1), K24AI001610 (1), M01RR000070 (1)