20 completed, 6 recruiting, 6 unknown, 2 withdrawn. 36 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 36 | Completed 20, Recruiting 6, Unknown 6, Withdrawn 2, Active not recruiting 1, Terminated 1 |
Follow Hyponatremia: new trials by email Literature Review of Hyponatremia trials Research Report on Hyponatremia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Protein Supplementation and Fluid Restriction on Plasma Sodium Levels in Patients Undergoing Pituitary Surgery Fluid restriction, Dietary protein supplementation, Standard post-operative care - Hyponatremia, Pituitary Surgery | Not applicable | Recruiting | University Hospital, Basel, Switzerland | 282 | 2026-01-20 | 2026-02-03 |
| Natriuresis-guided Depletion After Cardiac Surgery Furosemide intravenous titration based on natriuresis, Furosemide intravenous titration based on clinical examination - Cardiac Surgery, Diuresis | Not applicable | Recruiting | Centre Hospitalier Universitaire, Amiens | 102 | 2025-06-25 | 2026-01-21 |
| Protein Supplementation in Hyponatremia Due to the Syndrome of Inappropriate Antidiuresis Moltein PURE Protein Powder, Fluid restriction - Hyponatremia, Syndrome of Inappropriate Antidiuresis | Not applicable | Recruiting | University Hospital, Basel, Switzerland | 70 | 2025-04-14 | 2025-07-10 |
| Urea for Treatment of Hyponatremia in Patients With SIAD Unresponsive to Fluid Restriction urea - SIAD - Syndrome of Inappropriate Antidiuresis | Not applicable | Recruiting | University of Turin, Italy | 20 | 2024-09-12 | 2026-04-14 |
| Validation of New Diagnostic Indices to Simplify Hyponatremia Therapy Assessment in Patients on Thiazide Diuretics Standard Care, aSID/ChU Guided Therapy - Thiazide Associated Hyponatremia | Not applicable | Recruiting | University Hospital, Basel, Switzerland | 136 | 2024-05-06 | 2026-02-11 |
| Effects of Intravenous [Pyr1]Apelin-13 on Healthy Volunteers With Artificially Induced SIAD Placebo, Apelin Low Dose, Apelin High Dose - SIAD - Syndrome of Inappropriate Antidiuresis, Hyponatremia | Not applicable | Completed | University Hospital, Basel, Switzerland | 15 | 2024-03-01 | 2025-03-30 |
| Regulation of Extracellular Sodium in End Stage Renal Disease Upon Volume and Electrolyte Challenges Water administration, NaCl-Administration - Hyponatremia | Not applicable | Recruiting | University of Cologne | 60 | 2023-07-01 | 2025-09-17 |
| Comparison of Isotonic Versus Hypotonic Fluids in Neonates for Maintenance Fluid Therapy After Surgery Isotonic Saline with Dextrose - Hyponatremia, Hypernatremia | Not applicable | Completed | Rawalpindi Medical College | 84 | 2023-01-01 | 2024-07-03 |
| Effect of Protein Supplementation on Plasma Sodium Levels and Urinary Urea Excretion in Patients With SIAD Protein supplementation, Oral urea - Syndrome of Inappropriate Antidiuresis (SIAD) | Not applicable | Completed | University Hospital, Basel, Switzerland | 18 | 2021-10-08 | 2023-02-21 |
| Validation of Capillary Serum Sodium Levels Sodium determination - Nocturia | Not applicable | Completed | University Hospital, Ghent | 100 | 2021-04-30 | 2022-06-10 |
| Urea Therapy for Hyponatremia in Subarachnoid Hemorrhage Urea, PLACEBO - Hyponatremia, Subarachnoid Hemorrhage | Not applicable | Active not recruiting | University Hospital, Grenoble | 52 | 2020-12-03 | 2025-04-16 |
| Efficacy and Safety of Bolus Comparing With Continuous Drip of 3% NaCl in Patients With Severe Symptomatic Hyponatremia. 3%NaCl - Hyponatremia, Osmotic Demyelination Syndrome | Not applicable | Unknown | Department of Medical Services Ministry of Public Health of Thailand | 40 | 2020-09-30 | 2021-02-25 |
| New Tools for Predicting Capillary Leak Shock During Dengue Fever For each routine sample, an additional tube will be collected to measure the osmotic pressure in the blood and urine - Dengue Fever, Children | Not applicable | Unknown | Centre Hospitalier de Cayenne | 342 | 2020-05-14 | 2020-12-10 |
| Targeted Correction of Plasma Sodium Levels in Hospitalized Patients With Hyponatremia Targeted correction of plasma sodium levels, Standard care - Hyponatremia | Not applicable | Completed | University Hospital, Basel, Switzerland | 2278 | 2018-08-20 | 2025-07-11 |
| Prophylaxis Versus Treatment for TURP Syndrome. NaCl 3% HS, NaCl 0.9% NS - Transurethral Resection of Prostate Syndrome | Not applicable | Unknown | Ahmed Mohamed ELbadawy | 60 | 2018-02-10 | 2018-12-26 |
| The Association Between Hyponatremia and Osteoporosis in Patients With Epilepsy. Sodium chloride, Placebo Oral Tablet - Hyponatremia, Metabolic Bone Disease | Not applicable | Completed | Copenhagen University Hospital, Rigshospitalet | 21 | 2017-12-01 | 2019-03-28 |
| Osmolality of Oral Supplements and Ileostomy Output Isoosmolar, Hyperosmolar - Ileostomy - Stoma, Short Bowel Syndrome | Not applicable | Completed | University of Aarhus | 8 | 2017-06-01 | 2018-11-05 |
| Beer for Endurance Exercise Recovery Alcoholic Beer, Non alcoholic beer - Hyponatremia | Not applicable | Completed | State University of New York - Upstate Medical University | 43 | 2017-03-01 | 2018-04-26 |
| Comparison of Ringer Lactate and Isotonic Acetate Solution as Perioperative Maintenance Fluid for Children Ringer Lactate, Plasmalyte - Hyponatremia | Not applicable | Unknown | Post Graduate Institute of Medical Education and Research, Chandigarh | 50 | 2016-09-01 | 2016-10-18 |
| Hyponatremia Study (Delayed Hyponatremia After Pituitary Surgery) Fluid Restricted Group - Hyponatremia, Hyponatremic | Not applicable | Completed | Washington University School of Medicine | 300 | 2016-06-02 | 2024-07-23 |
Showing 20 of 36. Sign in to see all of them.
Inappropriate ADH Syndrome (6) · Diabetes Insipidus (2) · Edema (2) · Heart Failure (2) · Hypernatremia (2) · Pituitary Neoplasms (2) · Water-Electrolyte Imbalance (2) · Bone Diseases, Metabolic (1) · Dengue (1) · Gastroenteritis (1) · Hepatitis, Infectious Canine (1) · Hyperemia (1) · Hypertension (1) · Malnutrition (1)
Metabolic Diseases (36) · Nutritional and Metabolic Diseases (36) · Water-Electrolyte Imbalance (34) · Endocrine System Diseases (9) · Brain Diseases (8) · Central Nervous System Diseases (8) · Hypothalamic Diseases (8) · Nervous System Diseases (8) · Pituitary Diseases (8) · Cardiovascular Diseases (6) · Pathological Conditions, Signs and Symptoms (6) · Vascular Diseases (4) · Digestive System Diseases (3) · Pathologic Processes (3) · Signs and Symptoms (3)
Urea (3) · Saline Solution (2) · Sodium Chloride (2) · Standard of Care (2) · Apelin (1) · Blood Specimen Collection (1) · Diet, Sodium-Restricted (1) · Drug Therapy (1) · Glucose (1) · Hypodermoclysis (1) · Mannitol (1) · MoviPrep (1) · Plasmalyte A (1) · Ringer's Lactate (1) · Saline Solution, Hypertonic (1)
University Hospital, Basel, Switzerland (6) · University of Cologne (2) · Ahmed Mohamed ELbadawy (1) · Ann & Robert H Lurie Children's Hospital of Chicago (1) · Camilo Jose Cela University (1) · Centre Hospitalier Universitaire, Amiens (1) · Centre Hospitalier de Cayenne (1) · Copenhagen University Hospital, Rigshospitalet (1) · Department of Medical Services Ministry of Public Health of Thailand (1) · Far Eastern Memorial Hospital (1) · Finn Gustafsson (1) · Hospital General de Niños Pedro de Elizalde (1) · Istanbul University (1) · Karolinska University Hospital (1) · Mª del Carmen Lobo Rodríguez (1)
United States (7) · Switzerland (6) · France (4) · Denmark (3) · Germany (3) · Italy (3) · Spain (3) · Argentina (1) · Belgium (1) · Brazil (1) · Canada (1) · Croatia (1) · Egypt (1) · India (1) · Netherlands (1)
Mirjam Christ-Crain, Prof. Dr. med. (2) · Mirjam Christ-Crain, Prof. MD (2) · Volker Burst, MD (2) · Ahmed ELbadawy, MD (1) · Andrew S Little, MD (1) · Blandine De la Gastine, MD (1) · Carmen Lobo-Rodriguez, pHd (1) · David Kastenberg, MD (1) · Facundo A Jorro, MD (1) · Finn Gustafsson, MD, PhD, DMSci (1) · Gustavo De Baisi, MD (1) · Hendrik Vilstrup, Professor (1) · Jeremy Joslin, MD (1) · Johan Ullman, MD., PhD. (1) · Joseph G Verbalis, MD (1)
PMID 10824078, PMID 17913972, PMID 18272864, PMID 19523575, PMID 20345336, PMID 23912284, PMID 24148616, PMID 24246119, PMID 24569125, PMID 24944242, PMID 25066025, PMID 25472864, PMID 25683094, PMID 27156756, PMID 27777873, PMID 28174217, PMID 28356136, PMID 29871886, PMID 30396772, PMID 30882872, PMID 31221280, PMID 3309659, PMID 34552947, PMID 40084913, PMID 40646556, PMID 41057198, PMID 41733398
2014 (1), 2023 (1), 2025 (1)