37 completed, 22 recruiting, 14 not yet recruiting, 13 unknown. 29 Not applicable, 7 Phase 2, 6 Phase 3, 4 Phase 4, 2 Early Phase 1.
Follow Hyperemia: new trials by email Literature Review of Hyperemia trials Research Report on Hyperemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Portal and Splenic Venous Pulsatility in Postoperative Critically Ill Patients Venous Congestion, Postoperative Care | Not yet recruiting | Hospital Universitario de Gran Canaria Doctor Negrín | 60 | 2026-11-01 | 2026-09-17 | |
| Changes in Portal Vein Pulsatility Variability During a Tidal Volume Challenge Can Predict Fluid Tolerance Venous Congestion | Not yet recruiting | Hospital Universitario de Gran Canaria Doctor Negrín | 60 | 2026-11-01 | 2026-07-06 | |
| Therapeutic Strategies to Reduce Endothelial Ischemia-reperfusion Injury Ischemic preconditioning, Intravenous lactate infusion, No ischemic preconditioning (control) - Metabolic Syndrome, Vascular Injury | Early Phase 1 | Not yet recruiting | Gary Van Guilder | 68 | 2026-10-01 | 2025-02-13 |
| Structured Hemodynamic Assessment to Guide Care After Cardiac Surgery Expert Report of a Structured Hemodynamic Assessment, Standard Care (in control arm) - Cardiac Surgical Procedures, Hemodynamics | Not applicable | Not yet recruiting | Centre hospitalier de l'Université de Montréal (CHUM) | 75 | 2026-10-01 | 2026-10-20 |
| Right Ventriculo-Arterial Coupling During Fluid Loading in ICU Patients Echography - Shock, Right Ventricular Dysfunction | Recruiting | CHU de Reims | 100 | 2026-06-03 | 2026-06-10 | |
| Association of Microcirculation, Vexus Score and Femoral Vein Doppler in Patients on the ICU After Non-emergency Cardiac Surgery Microcirculatory Diffusion, Microcirculatory Convection Capacity | Recruiting | University Hospital, Basel, Switzerland | 40 | 2026-04-14 | 2026-08-25 | |
| Hemodynamic Venous Congestion Ultrasound (VExUS) by ICU Nurses in Sepsis Patients. Education in performing hemodynamic diagnostic ultrasound of venous congestion, Hemodynamic diagnostic ultrasound of venous congestion - Sepsis, Sepsis and Septic Shock | Not yet recruiting | Region Örebro County | 46 | 2026-04-01 | 2026-02-18 | |
| Vexus Assessment and Natriuresis-guided Diuretic Therapy in Acute Heart Failure Natriuresis-guided escalation of loop diuretics - Venous Congestion, Heart Failure Acute | Not applicable | Not yet recruiting | University Hospital, Akershus | 270 | 2026-04-01 | 2026-04-30 |
| Training Medical Residents in the Use of the Venous Excess UltraSound (VExUS) Score for Bedside Volume Assessment. In-person VExUS Training Program, Remote VExUS Training Program, No intervention - Acute Heart Failure (AHF), Fluid Over-load | Not applicable | Recruiting | Insel Gruppe AG, University Hospital Bern | 23 | 2026-03-20 | 2026-04-21 |
| VEXUS-REA : Evaluation of Ultrasound Parameters of Venous Congestion in Patients in a Medical Intensive Care Unit Venous ultrasound (inferior vena cava, portal vein, suprahepatic vein, and renal vein to calculate the VEXUS score ; femoral vein and popliteal vein) - Venous Congestion | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire de Besancon | 525 | 2026-03-01 | 2026-02-27 |
| Relationship Between the Level of Positive End-expiratory Pressure and Venous Congestion During Acute Respiratory Distress Syndrome. Non-interventionnal study - Mechanical Ventilation, Acute Respiratory Distress Syndrome (ARDS) | Not yet recruiting | University Hospital, Angers | 30 | 2026-03-01 | 2026-03-05 | |
| Renal and Hepatic Abnormal Doppler Patterns in Trauma Point of care ultrasound - Trauma (Including Fractures), Trauma Patients | Recruiting | Azienda Usl di Bologna | 350 | 2026-03-01 | 2026-03-25 | |
| Evolution of Tissue Perfusion and Venous Congestion Markers in Fluid-Responsive Septic Shock Patients Echography - Septic Shock, Fluid Resuscitation | Not yet recruiting | Hospital Ambroise Paré Paris | 200 | 2026-02-01 | 2025-05-06 | |
| Evaluation of the Association Between the VEXUS Score and Hemodynamic Status and the Occurrence of Acute Kidney Injury After Open-Heart Surgery Acute Kidney Injury After Open Heart Surgery, Venous Congestion After Open Heart Surgery | Recruiting | Hanoi Medical University | 135 | 2026-01-07 | 2026-09-04 | |
| Breastfeeding Education Through Clinical Demonstration for Primiparous Women to Prevent Sore Nipples and Engorgement breastfeeding positions and attachment practice. - Nipple Infection, Nipple Discharge | Not applicable | Not yet recruiting | Gadjah Mada University | 100 | 2025-12-26 | 2025-12-19 |
| Evaluating Injection With the Use of Brimonidine Tartrate Ophthalmic 0.025% on Patients Using Netarsudil 0.02%/Latanoprost 0.005% to Treat Glaucoma Brimonidine Tartrate Ophthalmic 0.025% - Glaucoma | Phase 4 | Recruiting | Insight Eyecare Specialties, Inc. dba Vision Source Eyecare, | 35 | 2025-11-01 | 2025-11-18 |
| Intracranial Pressure and a Potential Vicious Circle of Atrial Fibrillation in HFpEF Echocardiography - Heart Failure With Preserved Ejection Fraction (HFpEF), Atrial Fibrillation | Completed | Ankara Ataturk Sanatorium Training and Research Hospital | 309 | 2025-10-14 | 2026-04-09 | |
| Effects of Positive End-Expiratory Pressure (PEEP) and Prone Positioning in Healthy Volunteers on Venous Hemodynamics Including the Venous Excess Ultrasound (VExUS) Score application of PEEP: starting PEEP = 15 mbar, application of PEEP: starting PEEP = 0 mbar - Venous Hemodynamics | Not applicable | Completed | University Hospital, Basel, Switzerland | 40 | 2025-09-25 | 2026-08-21 |
| Impact of Fluid Resuscitation on Venous Congestion in Cardiac Critically-ill Patients VExUS & Cardiac Ultrasound - Cardiac and Aortic Surgery, Cardiac Anaesthesia | Not yet recruiting | Medical University of Vienna | 250 | 2025-09-15 | 2025-09-19 | |
| Right Ventricular Function Changes After CIED Implantation: The RIGHT-CIED Study Multimodal Right Ventricular Evaluation - Right Ventricular Dysfunction | Recruiting | Istanbul University - Cerrahpasa | 40 | 2025-08-15 | 2025-12-16 |
Showing 20 of 91. Sign in to see all of them.
Acute Kidney Injury (11) · Heart Failure (7) · Breast Feeding (5) · Edema (5) · Dry Eye Syndromes (4) · Pain (4) · Cardio-Renal Syndrome (3) · Glaucoma (3) · Keratoconjunctivitis Sicca (3) · Renal Insufficiency (3) · Sepsis (3) · Shock, Septic (3) · Ventricular Dysfunction, Right (3) · Aneurysm (2)
Vascular Diseases (91) · Cardiovascular Diseases (90) · Pathological Conditions, Signs and Symptoms (29) · Female Urogenital Diseases and Pregnancy Complications (19) · Pathologic Processes (19) · Urogenital Diseases (19) · Heart Diseases (18) · Female Urogenital Diseases (16) · Male Urogenital Diseases (16) · Urologic Diseases (16) · Kidney Diseases (15) · Signs and Symptoms (15) · Renal Insufficiency (12) · Respiratory Tract Diseases (8) · Behavior (7)
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Bausch & Lomb Incorporated (3) · Georgia State University (3) · Kala Pharmaceuticals, Inc. (3) · Zhuan Zhang (3) · Centre Hospitalier Universitaire, Amiens (2) · Hospices Civils de Lyon (2) · Hospital Universitario de Gran Canaria Doctor Negrín (2) · Insel Gruppe AG, University Hospital Bern (2) · Istanbul University - Cerrahpasa (2) · Stanford University (2) · University Hospital, Basel, Switzerland (2) · University Hospital, Grenoble (2) · University of Iowa (2) · Aarhus University Hospital (1) · Agri Ibrahim Cecen University (1)
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PMID 32270297, PMID 10793162, PMID 12727395, PMID 14768311, PMID 15269312, PMID 18270352, PMID 19318356, PMID 20394872, PMID 20576199, PMID 22647519, PMID 22693347, PMID 24057589, PMID 24062375, PMID 24304033, PMID 24578332, PMID 26426034, PMID 26591707, PMID 27179835, PMID 28775050, PMID 29461408, PMID 29804762, PMID 31080479, PMID 31630601, PMID 32683213, PMID 32826644, PMID 32944940, PMID 33076961, PMID 33385260, PMID 34632507, PMID 36017548, PMID 36184294, PMID 36949505, PMID 37237315, PMID 37291662, PMID 37486652, PMID 37577933, PMID 37749114, PMID 37863161, PMID 38299348, PMID 38462160, PMID 38512544, PMID 38706945, PMID 39282762, PMID 39439007, PMID 39589643, PMID 39686672, PMID 40515791, PMID 41057198, PMID 41538804, PMID 41606663
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