11 completed, 4 unknown, 3 active not recruiting, 2 recruiting. 10 Not applicable, 6 Phase 2, 4 Phase 1, 2 Phase 3, 2 Phase 4.
Follow Urea: new trials by email Literature Review of Urea trials Research Report on Urea
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Acetic Acid Ear Drops Versus 0.3 % Ciprofloxacin for Chronic Suppurative Otitis Media. Acetic Acid 2% Ear Drops, Ciprofloxacin 0.3% Otic Solution - Otitis Media Chronic | Not applicable | Not yet recruiting | Dow University of Health Sciences | 146 | 2026-09-23 | 2026-09-22 |
| Photodynamic Therapy For Onychomycosis ALA 10% gel, PDT, Urea - Onychomycosis of Toenail | Phase 1 | Active not recruiting | The University of Texas Health Science Center, Houston | 5 | 2026-08-10 | 2026-10-06 |
| Adding Urea to the Final Dialysis Fluid Urea in the dialysate - Dysequilibrium Syndrome, ESRD | Phase 1 / Phase 2 | Recruiting | University of California, San Francisco | 20 | 2025-09-16 | 2026-02-12 |
| Exploring Different Dose-frequency Home Photodynamic Therapy Protocols Using a Novel Home-targeted LED Device for Onychomycosis Photodynamic Therapy with Conventional Methylene Blue, urea 40% cream - Onychomycosis of Toenails, Onychomycosis of Fingernail | Not applicable | Active not recruiting | Chulalongkorn University | 50 | 2025-01-13 | 2026-05-12 |
| Effectiveness of CBD for Neuropathic Pain in Diabetic Foot Neuropathy Group 1. Complete formula, Group 2. Cannabidiol and Urea 10% formula., Group 3. Placebo formula. - Xerosis Cutis, Neuropathic Pain Associated With Diabetic Peripheral Neuropathy | Not applicable | Completed | Universidad Complutense de Madrid | 23 | 2024-11-01 | 2025-10-01 |
| Urea for Treatment of Hyponatremia in Patients With SIAD Unresponsive to Fluid Restriction urea - SIAD - Syndrome of Inappropriate Antidiuresis | Not applicable | Recruiting | University of Turin, Italy | 20 | 2024-09-12 | 2026-04-14 |
| Plasma Copeptin in Response to Oral Urea in Healthy Adults and Patients With Polyuria-polydipsia Syndrome Urea, Placebo - Arginine Vasopressin Deficiency, Primary Polydipsia | Not applicable | Completed | University Hospital, Basel, Switzerland | 48 | 2023-06-02 | 2024-07-09 |
| Effect of Topical Diclofenac on Clinical Outcome in Breast Cancer Patients Treated With Capecitabine (CARBAMIDE®), (VOLTAREN®) Emulgel 1% - Hand and Foot Syndrome | Phase 2 | Completed | German University in Cairo | 86 | 2022-12-08 | 2024-01-03 |
| Urea for Chronic Hyponatremia Urea - Hyponatremia, Inappropriate ADH Syndrome | Phase 2 | Terminated | Helbert Rondon Berrios, MD, MS | 2 | 2021-12-28 | 2024-05-20 |
| Effect of Protein Supplementation on Plasma Sodium Levels and Urinary Urea Excretion in Patients With SIAD Protein supplementation, Oral urea - Syndrome of Inappropriate Antidiuresis (SIAD) | Not applicable | Completed | University Hospital, Basel, Switzerland | 18 | 2021-10-08 | 2023-02-21 |
| Antifungal Potential of Moringa Olifera Against Otomycosis Moringa oleifera leaf 10mg/100ml, Ear Drop - Otomycosis | Early Phase 1 | Completed | Deraya University | 10 | 2021-02-18 | 2022-03-09 |
| Urea Therapy for Hyponatremia in Subarachnoid Hemorrhage Urea, PLACEBO - Hyponatremia, Subarachnoid Hemorrhage | Not applicable | Active not recruiting | University Hospital, Grenoble | 52 | 2020-12-03 | 2025-04-16 |
| Systemic Uptake of Diclofenac Sodium in Combination With Miconazole as Antifungal Nail Gel When Applied Daily With Monitoring of Hepatic and Renal Enzymes, and Serum Levels of Diclofenac 12 Hours After Application, and at 3 and 6 Months Study Antifungal Nail Gel Study - Tinea Unguium, Onychomycosis | Phase 2 | Unknown | William N Handelman | 30 | 2020-05-01 | 2020-04-10 |
| Pazufloxacin Mesilate Ear Drops in Patients With Chronic Suppurative Otitis Media Pazufloxacin Mesilate ear drops - Chronic Suppurative Otitis Media | Phase 1 | Unknown | Lee's Pharmaceutical Limited | 33 | 2018-07-29 | 2018-09-26 |
| Comparison of 12% Ammonium Lactate and 10% Urea Cream in Geriatric With Xerosis Cutis Ammonium Lactate, Urea - Xerosis Cutis | Phase 3 | Completed | Universitas Indonesia | 40 | 2017-04-01 | 2019-10-15 |
| Treatment of Onychomycosis With Loceryl (Amorolfine) Nail Lacquer 5% Versus a Two-course Treatment With Urea 40% Ointment and Bifonazole Cream 1% Loceryl Nail Lacquer, Urea Ointment, Bifonazole Cream - Foot Dermatoses | Phase 4 | Completed | Galderma R&D | 22 | 2016-01-01 | 2021-02-17 |
| Subcutaneous Immunotherapy for Mouse in Adults Mouse Allergenic Extract - Asthma, Perennial Allergic Rhinitis | Phase 1 / Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 12 | 2015-10-01 | 2018-03-07 |
| Vaginal Fluid Wash in Pre-labour Rupture of Membranes Urea and creatinine, Nitrazine, 5ml saline - Disorder of Amniotic Cavity and/or Membrane | Not applicable | Unknown | Beni-Suef University | 105 | 2014-05-01 | 2021-02-16 |
| Mother-caregivers of Children With Duchenne Muscular Dystrophy sleep parameters, Hormonal profile, Inflammatory profile - Other Diseases or Conditions | Not applicable | Completed | Monica Levy Andersen | 60 | 2013-08-01 | 2016-02-03 |
| Sorafenib-induced Hand- Foot Skin Reaction Treatment urea 40% cream, fluocinonide 0.05% cream, tazarotene 0.1% cream - Hand-foot Skin Reaction, Rash | Phase 2 | Terminated | Northwestern University | 6 | 2008-06-01 | 2013-06-05 |
Showing 20 of 23. Sign in to see all of them.
Hyponatremia (4) · Inappropriate ADH Syndrome (4) · Onychomycosis (3) · Acidosis (1) · Asthma (1) · Breast Neoplasms (1) · Dermatitis, Atopic (1) · Diabetes Insipidus (1) · Diabetes Insipidus, Neurogenic (1) · Diabetes Mellitus (1) · Diabetic Foot (1) · Diabetic Neuropathies (1) · Dysequilibrium syndrome (1) · Endocrine System Diseases (1) · Exanthema (1)
ACO Hud Nordic AB (2) · University Hospital, Basel, Switzerland (2) · Beni-Suef University (1) · Chulalongkorn University (1) · Deraya University (1) · Dow University of Health Sciences (1) · Galderma R&D (1) · German University in Cairo (1) · Helbert Rondon Berrios, MD, MS (1) · Lee's Pharmaceutical Limited (1) · Monica Levy Andersen (1) · National Center for Research Resources (NCRR) (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Northwestern University (1) · The University of Texas Health Science Center, Houston (1)
United States (7) · Egypt (3) · Switzerland (2) · Brazil (1) · China (1) · France (1) · Iceland (1) · Indonesia (1) · Italy (1) · Norway (1) · Pakistan (1) · Spain (1) · Sweden (1) · Thailand (1)
Agneta L. Sunehag (1) · Berit Berne, MD (1) · Dennis West, PhD (1) · Gro Moerk, MD (1) · Helbert Rondon Berrios, MD. MS (1) · Mirjam Christ-Crain, Prof. (1) · Mirjam Christ-Crain, Prof. Dr. med. (1) · Nesreen A Shehata, MD (1) · Ramin Sam, MD (1) · Robert Wood, M.D. (1) · Soad A Mohamad (1) · Stephen Tyring, MD, PhD, MBA (1)
2023 (1), R21DK122023 (1)