High Blood Pressure: Clinical Trials

5 completed, 3 withdrawn, 1 active not recruiting, 1 not yet recruiting. 12 Phase 2, 3 Phase 1, 1 Phase 3.

By phase and status

Phase	Trials	Status
Phase 2	12	Completed 5, Withdrawn 3, Active not recruiting 1, Not yet recruiting 1, Recruiting 1, Terminated 1
Phase 1	3	Active not recruiting 1, Recruiting 1, Withdrawn 1
Phase 3	1	Withdrawn 1

Follow High Blood Pressure: new trials by email Literature Review of High Blood Pressure trials Research Report on High Blood Pressure

Trials (filtered) newest first · largest first

All 12 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Evaluation of Superiority of Valsartan+Celecoxib+Metformin Over Metformin Alone in Type 2 Diabetes Patients Metformin, Val, Cel and Met XR Low, Val, Cel and Met XR High - Type 2 Diabetes, High Blood Pressure	Phase 1 / Phase 2	Withdrawn	ARKAY Therapeutics		2026-12-10	2026-07-16
Effect of an Isolevuglandin Scavenger on Salt Sensitivity of Blood Pressure and Immune Cell Activation in Humans 2-hydroxybenzylamine, Placebo - Salt Sensitivity of Blood Pressure, High Blood Pressure	Phase 2	Not yet recruiting	Vanderbilt University Medical Center	20	2026-09-01	2026-07-28
Polypill for Prevention of Cardiomyopathy Polypill, Combined prescription of the individual medications - Type 2 Diabetes, High Blood Pressure	Phase 1 / Phase 2	Recruiting	University of Texas Southwestern Medical Center	200	2024-03-11	2026-08-04
Salt-Sensitivity and Immunity Cell Activation Furosemide 40 mg - High Blood Pressure, Salt; Excess	Phase 1 / Phase 2	Active not recruiting	Vanderbilt University Medical Center	20	2021-09-01	2025-10-21
Acupuncture Treatment on Cerebral Blood Flow Acupuncture - High Blood Pressure	Phase 2	Withdrawn	University of Oklahoma		2020-05-09	2023-11-30
Effect of Vitamin D Supplementation on Blood Pressure in Elderly People Calcitriol, Control - High Blood Pressure	Phase 2	Completed	Universidad de Colima	45	2013-04-01	2017-11-13
Safety Study of Nebivolol for COPD Patients Placebo, Nebivolol - High Blood Pressure	Phase 2 / Phase 3	Withdrawn	University of Chicago		2012-01-01	2016-01-12
The Effect of Dexmedetomidine on Hemodynamic Response During Double Lumen Endotracheal Intubation Dexmedetomidine, Placebo - Intubation Complication, Tracheal Intubation Morbidity	Phase 2	Completed	Chiang Mai University	60	2011-03-01	2011-12-15
Lifestyle Modification and Blood Pressure Study Yoga exercise program, Blood pressure education/walking program - High Blood Pressure	Phase 2	Completed	University of Pennsylvania	147	2009-08-01	2017-02-15
Comparison of Aliskiren and Amlodipine on Insulin Resistance and Endothelial Dysfunction in Patients With Hypertension and Metabolic Syndrome Aliskiren, Amlodipine, Placebo Aliskiren - High Blood Pressure, Metabolic Syndrome	Phase 2	Completed	Novartis Pharmaceuticals	48	2007-10-01	2011-09-26
Telephone-Based Lifestyle Intervention to Reduce Blood Pressure in Prehypertensive Patients Telephone-based lifestyle counseling - High Blood Pressure	Phase 2	Terminated	NYU Langone Health	125	2007-01-01	2013-11-19
Stress Reduction and Hypertension Prevention in African Americans Health Education, Transcendental Meditation - High Blood Pressure	Phase 2	Completed	Maharishi International University	304	1998-05-01	2021-05-07

Narrower conditions

Hypertension (12)  ·  Diabetes Mellitus, Type 2 (2)  ·  Inflammation (2)  ·  Arthritis (1)  ·  Cardiovascular Diseases (1)  ·  Diabetes Mellitus (1)  ·  Diabetic Cardiomyopathies (1)  ·  Glucose Intolerance (1)  ·  Insulin Resistance (1)  ·  Metabolic Syndrome (1)  ·  Obesity (1)  ·  Prehypertension (1)  ·  Pulmonary Disease, Chronic Obstructive (1)  ·  Tachycardia (1)

Broader conditions

Vascular Diseases (12)  ·  Cardiovascular Diseases (11)  ·  Pathological Conditions, Signs and Symptoms (5)  ·  Pathologic Processes (4)  ·  Glucose Metabolism Disorders (3)  ·  Metabolic Diseases (3)  ·  Nutritional and Metabolic Diseases (3)  ·  Endocrine System Diseases (2)  ·  Heart Diseases (2)  ·  Arrhythmias, Cardiac (1)  ·  Body Weight (1)  ·  Cardiac Conduction System Disease (1)  ·  Cardiomyopathies (1)  ·  Chronic Disease (1)  ·  Diabetes Complications (1)

Interventions

2-(aminomethyl)phenol (1)  ·  Acupuncture Therapy (1)  ·  Amlodipine (1)  ·  Calcitriol (1)  ·  Carboxylesterase (1)  ·  Celecoxib (1)  ·  Dexmedetomidine (1)  ·  Furosemide (1)  ·  Losartan (1)  ·  Meditation (1)  ·  Metformin (1)  ·  Nebivolol (1)  ·  Valine (1)  ·  Valsartan (1)  ·  aliskiren (1)

Sponsors

Vanderbilt University Medical Center (2)  ·  ARKAY Therapeutics (1)  ·  Chiang Mai University (1)  ·  Maharishi International University (1)  ·  NYU Langone Health (1)  ·  Novartis Pharmaceuticals (1)  ·  Universidad de Colima (1)  ·  University of Chicago (1)  ·  University of Oklahoma (1)  ·  University of Pennsylvania (1)  ·  University of Texas Southwestern Medical Center (1)

Countries

United States (9)  ·  Mexico (1)  ·  Thailand (1)

Top investigators

Ambarish Pandey, MD, MSCS (1)  ·  Annet Kirabo (1)  ·  Debbie Cohen, M.D. (1)  ·  George Bakris, MD (1)  ·  Jaime A Bricio Barrios (1)  ·  Jeremy M Kellawan, PhD (1)  ·  Matthew M Burg (1)  ·  Ravi Kumar, Ph.D. (1)  ·  Robert H Schneider, M.D. (1)  ·  Tanya M Goyal, PhD (1)  ·  Tanyong Pipanmekaporn, MD (1)

Results publications

PMID 11230313, PMID 12147930, PMID 1846122, PMID 1860713, PMID 1879381, PMID 23721984, PMID 23983684, PMID 26773737, PMID 27897610, PMID 3522418, PMID 37534363, PMID 37675576, PMID 41052782