96 completed, 25 unknown, 10 terminated, 9 not yet recruiting. 103 Not applicable, 17 Phase 2, 14 Phase 4, 11 Phase 3, 6 Phase 1.
Follow Prehypertension: new trials by email Literature Review of Prehypertension trials Research Report on Prehypertension
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Behaviour Change Wheel Intervention to Promote Healthy Behaviors in Adults With Prehypertension Behaviour Change Wheel-Based Health-Promoting Behavior Intervention, Routine Health Education - Prehypertension | Not applicable | Not yet recruiting | Fujian Medical University Union Hospital | 94 | 2026-11-01 | 2026-10-19 |
| Guided Physical Activity Counseling for Hypertension in Primary Care Physical activity counseling - Physical Activity, Hypertension | Not applicable | Not yet recruiting | University of California, San Diego | 330 | 2026-10-01 | 2026-01-15 |
| Neurovascular Effects of Empagliflozin Empagliflozin (EMPA), Placebo - Blood Pressure, Endothelial Dysfunction | Phase 4 | Not yet recruiting | Kanokwan Bunsawat | 100 | 2026-09-01 | 2026-09-02 |
| A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity Orforglipron, Placebo - Overweight, Prediabetic State | Phase 3 | Recruiting | Eli Lilly and Company | 2001 | 2026-08-26 | 2026-11-05 |
| Cardiovascular Effects of Purple-Fleshed Potatoes Purple flesh potato, White flesh potato - PRE-HYPERTENSION | Not applicable | Not yet recruiting | Instituto de Investigacion Nutricional, Peru | 300 | 2026-08-01 | 2026-07-29 |
| Cohort Study of Metabolic Disease and Hypertension Observational Study - Type 2 Diabetes Mellitus (T2DM), Hypertension (HTN) | Not yet recruiting | Coordinación de Investigación en Salud, Mexico | 2500 | 2026-06-01 | 2026-05-11 | |
| A Clinical Trial of an Herbal Liquid Supplement - 'DBPS' for Managing Blood Pressure DBPS, Placebo - Prehypertension | Not applicable | Not yet recruiting | Eetho Brands, Inc | 198 | 2026-05-15 | 2026-06-05 |
| Efficacy of Nigella Sativa (Nisatol®) in Women With Borderline Blood Pressure Values or a Non-Dipper Blood Pressure Phenotype Nigella sativa (Nisatol®), Placebo - Prehypertension, Hypertension | Not applicable | Not yet recruiting | Liaquat University of Medical & Health Sciences | 106 | 2026-03-30 | 2026-03-27 |
| Remotely Delivered Resistance Training for Cardiometabolic Health Among Black Women Resistance Training - Overweight or Obesity, Prediabetes or Diabetes | Not applicable | Active not recruiting | University of Alabama at Birmingham | 37 | 2026-03-19 | 2026-10-14 |
| Additional Effects of Pilates Breathing and Diaphragmatic Breathing Combined With Moderate Intensity Continuous Treadmill Training on Blood Pressure, Chest Expansion, Pulmonary Function and Quality Of Life in Pre-hypertensive Patients Treadmill Training (Moderate-intensity continuous training), Pilates Breathing, Diaphragmatic Breathing - PRE-HYPERTENSION | Not applicable | Recruiting | Foundation University Islamabad | 45 | 2026-02-28 | 2026-04-14 |
| The Effects of Brief Periods of Exercise on Blood Pressure wall-squat, wall-squat-tradition - Hypertension (HTN), Pre Hypertension | Not applicable | Recruiting | University of Hartford | 45 | 2026-02-01 | 2026-05-01 |
| Breathing Exercises of CardioBreath Application on Autonomic and Vascular Function in Hypertension CardioBreath - Hypertension, Pre Hypertension | Not applicable | Not yet recruiting | Instituto de Cardiologia do Rio Grande do Sul | 66 | 2025-08-01 | 2025-04-08 |
| Difference in Acute Responses of Vascular Function to Moderate-intensity and High-intensity Interval Training in Healthy and Prehypertensive Individuals Control-no treatment, Exercise - Prehypertension (Elevated Blood Pressure) or Hypertension, Healthy | Not applicable | Recruiting | University of Ljubljana | 45 | 2025-06-24 | 2026-10-19 |
| Evaluation of Physical Fitness and Hemodynamics Across a Diverse Population Prehypertension (Elevated Blood Pressure) or Hypertension, Obesity and Obesity-related Medical Conditions | Recruiting | University of Ljubljana | 30 | 2024-11-04 | 2026-05-12 | |
| Weight Inclusive and Adaptive Strategies to Enhance Cardiometabolic Health in Black Adults Weight-focused health coaching, Weight-neutral health coaching, Intensify lifestyle approach - Obesity, Prehypertension | Not applicable | Completed | University of Alabama at Birmingham | 41 | 2024-10-01 | 2026-02-27 |
| Impact of Sex in the Effect of Dietary Capsaicin on Cardiovascular Health Dietary capsules - Pre Hypertension, Hypertension | Not applicable | Unknown | Skidmore College | 80 | 2024-07-08 | 2024-07-10 |
| Combined Effects of Isometric Wall Squats and High Intensity Interval Training on Rate Pressure Product in Normotensive and Pre-hypertensive Sedentary Adults High Intensity Interval Training (HIIT), Isometric Wall Squat - Pre Hypertension | Not applicable | Unknown | Foundation University Islamabad | 44 | 2024-06-10 | 2024-09-24 |
| Instant Message-delivered Personalised Lifestyle Modification Intervention for Pre-hypertension Adults Receiving LSM messages., Receiving brief pre-HTN messages. - Pre-hypertension, Lifestyle Modification | Not applicable | Unknown | The University of Hong Kong | 256 | 2024-05-01 | 2024-07-17 |
| Effects of Pilate Training Versus Moderate Intensity Continous Training in Hypertensive Patients Moderate-Intensity continuous training - Prehypertension | Not applicable | Active not recruiting | Riphah International University | 52 | 2024-04-20 | 2025-01-07 |
| Pranayama and Jacobson's Progressive Muscle Relaxation Technique in Pre-hypertensive Patients Pranayama, Jacobson's progressive muscle relaxation technique - Prehypertension | Not applicable | Enrolling by invitation | Riphah International University | 50 | 2024-04-15 | 2024-10-24 |
Showing 20 of 158. Sign in to see all of them.
Hypertension (89) · Obesity (24) · Prediabetic State (13) · Overweight (9) · Cardiovascular Diseases (7) · Diabetes Mellitus, Type 2 (6) · Motor Activity (6) · Diabetes Mellitus (5) · Glucose Intolerance (5) · Insulin Resistance (5) · Metabolic Syndrome (5) · Essential Hypertension (3) · Obesity, Abdominal (3) · Acquired Immunodeficiency Syndrome (2)
Vascular Diseases (158) · Cardiovascular Diseases (151) · Nutritional and Metabolic Diseases (42) · Pathological Conditions, Signs and Symptoms (32) · Signs and Symptoms (30) · Nutrition Disorders (27) · Overnutrition (26) · Body Weight (25) · Glucose Metabolism Disorders (24) · Metabolic Diseases (24) · Endocrine System Diseases (19) · Overweight (17) · Behavior (16) · Diabetes Mellitus (13) · Hyperinsulinism (9)
Amlodipine (3) · Diet (3) · Diet, Sodium-Restricted (3) · Exercise (3) · Metoprolol (3) · Nebivolol (3) · Allopurinol (2) · Amiloride (2) · Hydrochlorothiazide (2) · Resistance Training (2) · allisartan isoproxil (2) · Acetic Acid (1) · Actigraphy (1) · Ascorbic Acid (1) · Auriculotherapy (1)
University of Alabama at Birmingham (6) · Florida State University (5) · University of California, San Diego (5) · Johns Hopkins University (4) · Brown University (3) · Riphah International University (3) · California Baptist University (2) · Capital Medical University (2) · Duke University (2) · Emory University (2) · Foundation University Islamabad (2) · Hospital de Clinicas de Porto Alegre (2) · KGK Science Inc. (2) · Massachusetts General Hospital (2) · Pusan National University (2)
United States (82) · China (8) · South Korea (8) · Brazil (7) · Pakistan (5) · United Kingdom (5) · Canada (4) · India (3) · Italy (3) · Mexico (3) · Taiwan (3) · Argentina (2) · Czechia (2) · Germany (2) · Slovenia (2)
Arturo Figueroa, M.D., Ph.D (3) · Eric B Loucks, PhD (2) · Alberto J Alves, PhD (1) · Alexei Wong (1) · Alok Gupta, MD, AAFP, FASH (1) · Amber W Kinsey, PhD (1) · Antti Jula, Dr. (1) · Armin Paravlic, PhD (1) · Arnon Aharon, MD. (1) · Arturo Figueroa, M.D., Ph.D. (1) · Baukje de Roos (1) · Bethany Barone Gibbs, PhD (1) · Betul Kuzu (1) · Britt Burton-Freeman, Ph.D (1)
PMID 37218591, PMID 37292774, PMID 37917063, PMID 42291030, PMID 11581560, PMID 16476851, PMID 19120715, PMID 20018807, PMID 21849262, PMID 22458601, PMID 23006736, PMID 23171375, PMID 23227315, PMID 23382493, PMID 24410943, PMID 24637663, PMID 24808486, PMID 24871654, PMID 25359163, PMID 25480461, PMID 25633634, PMID 25770758, PMID 26451070, PMID 26471194, PMID 26653067, PMID 26843120, PMID 27113048, PMID 27356482, PMID 27965209, PMID 28447625, PMID 28452620, PMID 29122812, PMID 29227377, PMID 29371241, PMID 29968437, PMID 30010353, PMID 30087093, PMID 30389646, PMID 30540702, PMID 31079530, PMID 31467699, PMID 31774807, PMID 32205788, PMID 32314970, PMID 32475312, PMID 32496401, PMID 32847397, PMID 32877573, PMID 33190559, PMID 33512717
P50MD017338 (2), 1UH2AT009145 (1), 1UH2AT009145-01 (1), 5UH3AT009145-04 (1), K23HL119622 (1), K23HL146887 (1), P50AR060772 (1), R01HL088567 (1), R01HL096593 (1), R01HL115082 (1), R01HL134808 (1), R01HL134809 (1), R01NR004861 (1), R21DK071223 (1), R21TW011693 (1)