12 completed, 5 recruiting, 5 unknown, 2 active not recruiting. 8 Not applicable, 5 Phase 2, 2 Phase 1, 2 Phase 3, 1 Phase 4.
Follow Diabetic Cardiomyopathies: new trials by email Literature Review of Diabetic Cardiomyopathies trials Research Report on Diabetic Cardiomyopathies
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Soluble TREM-1 in Diabetes-Associated Cardiovascular Complications Type 2 Diabetes Mellitus, Cardiovascular Diseases | Not yet recruiting | Assiut University | 85 | 2026-10-01 | 2026-09-29 | |
| Cardioprotective Effects of SGLT2 Inhibitors and GLP-1 Receptor Agonists in Korean Patients With Type 2 Diabetes Type 2 Diabetes Mellitus (T2DM), Cardiovascular Diseases | Not yet recruiting | Dongtan Sacred Heart Hospital | 100 | 2026-09-01 | 2026-08-18 | |
| Diabetic Cardiomyopathy and Heart Failure Probiotic - Diabetic Cardiomyopathies, Heart Failure | Not applicable | Withdrawn | University of Louisville | 2025-07-01 | 2025-01-31 | |
| Tailored Exercise Training Study Among Adults With HFpEF Moderate-intensity continuous training (MCT), Resistance training, Weight loss - HFpEF - Heart Failure With Preserved Ejection Fraction, Diabetic Cardiomyopathies | Phase 2 / Phase 3 | Recruiting | University of Texas Southwestern Medical Center | 120 | 2025-02-18 | 2025-10-31 |
| NT-ProBNP-based Heart Failure Screening and Prevention Trial in Patients With Type 2 Diabetes: STRONG-DM Study Intensive Prevention Strategy - Type 2 Diabetes, Diabetic Cardiomyopathy | Not applicable | Recruiting | University of Texas Southwestern Medical Center | 300 | 2025-02-10 | 2026-09-29 |
| Polypill for Prevention of Cardiomyopathy Polypill, Combined prescription of the individual medications - Type 2 Diabetes, High Blood Pressure | Phase 1 / Phase 2 | Recruiting | University of Texas Southwestern Medical Center | 200 | 2024-03-11 | 2026-08-04 |
| CMR in T2DM: The NSR Cohort All subjects will undergo cardiac magnetic resonance imaging with gadolinium contrast and with adenosine myocardial perfusion - Diabetes Mellitus, Type 2, Diabetic Cardiomyopathies | Enrolling by invitation | Slagelse Hospital | 700 | 2023-04-01 | 2023-06-22 | |
| Efficacy of Trimetazidine in Diabetic Patients Trimetazidine Dihydrochloride, Placebo - Diabetes Mellitus, Type 2, Diabetic Cardiomyopathies | Phase 2 | Unknown | Ain Shams University | 60 | 2022-09-18 | 2022-09-27 |
| Mitochondrial Substrate Utilization in the Diabetic Human Heart Heart Failure, Type2diabetes | Recruiting | Heinrich-Heine University, Duesseldorf | 500 | 2021-12-01 | 2026-02-19 | |
| Impact of Prediabetes on Acute Coronary Syndrome Troponin, Lipid profile, HBA1C, Fasting blood glucose level, Creatinine, Body Mass Index - Diabetic Cardiomyopathy | Completed | Sohag University | 100 | 2021-08-01 | 2022-08-31 | |
| IMPROVE-DiCE: Study to Evaluate Effect of IMB-1018972 on Cardiac Energetics in T2DM & Obesity (Pt 1) With HFpEF (Pt 2) IMB-1018972 - Type 2 Diabetes, Diabetic Cardiomyopathies | Phase 2 | Completed | Imbria Pharmaceuticals, Inc. | 49 | 2021-04-21 | 2025-06-29 |
| Evaluation of Alpha-Lipoic Acid in Diabetic Cardiomyopathy Physiomance acide lipoïque gold, Placebo - Physiomance acide lipoïque gold - Diabetic Cardiomyopathies | Not applicable | Terminated | Centre Hospitalier Universitaire de Nice | 13 | 2020-11-24 | 2024-02-05 |
| CARdiomyopathy in Type 2 DIAbetes Mellitus Cardiomyopathy, Diabetic | Active not recruiting | Institut National de la Santé Et de la Recherche Médicale, France | 1256 | 2020-10-02 | 2026-05-06 | |
| Diabetic Cardiomyopathy Diabetic Cardiomyopathies | Unknown | University Hospital, Strasbourg, France | 77 | 2020-10-01 | 2021-10-12 | |
| Single-center Clinical Study of Early Diagnosis of Diabetic Cardiomyopathy With FLIM fluorescence lifetime imaging microscopy - Diabetic Cardiomyopathies | Unknown | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | 243 | 2020-10-01 | 2020-09-01 | |
| The DAPA-MEMRI Trial Dapagliflozin 10 milligrams [Farxiga], Placebo - Heart Failure, Diabetic Cardiomyopathies | Not applicable | Completed | University of Edinburgh | 81 | 2020-08-19 | 2026-09-23 |
| Safety and Efficacy of AT-001 in Patients With Diabetic Cardiomyopathy AT-001, Placebo - Diabetic Cardiomyopathies | Phase 3 | Active not recruiting | Applied Therapeutics, Inc. | 675 | 2019-09-20 | 2022-12-08 |
| Assessment of Myocardial Injury in Simultaneous Pancreas and Kidney Transplantation cardiac magnetic resonance(CMR) T2 mapping - Simultaneous Pancreas-kidney Transplantation, Diabetic Cardiomyopathy | Unknown | Tianjin First Central Hospital | 50 | 2019-04-01 | 2019-04-05 | |
| Preclinical Cardiomyopathy and Autonomic Function in Type 1 Diabetes Diabetes Mellitus, Type 1, Diabetic Cardiomyopathies | Completed | Roberto Léo da Silva | 80 | 2018-07-06 | 2019-10-08 | |
| Prevalence and Determinants of Subclinical Cardiovascular Dysfunction in Adults With Type 2 Diabetes Mellitus Cardiovascular magnetic resonance (CMR) imaging and magnetic resonance spectroscopy, Transthoracic echocardiography, Computed tomography coronary artery calcium scoring - Diabetes Mellitus, Type 2, Diabetic Cardiomyopathies | Recruiting | University of Leicester | 593 | 2017-10-24 | 2024-01-05 |
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Diabetes Mellitus, Type 2 (16) · Diabetes Mellitus (6) · Heart Failure (5) · Cardiomyopathies (3) · Cardiovascular Diseases (2) · Diabetes Complications (2) · Arrhythmias, Cardiac (1) · Coronary Artery Disease (1) · Diabetes Mellitus, Type 1 (1) · Diabetic Neuropathies (1) · Fibrosis (1) · Hypertension (1) · Inflammation (1) · Insulin Resistance (1)
Endocrine System Diseases (29) · Heart Diseases (29) · Cardiovascular Diseases (27) · Diabetes Complications (27) · Cardiomyopathies (26) · Diabetes Mellitus (23) · Glucose Metabolism Disorders (19) · Metabolic Diseases (19) · Nutritional and Metabolic Diseases (19) · Pathological Conditions, Signs and Symptoms (4) · Pathologic Processes (3) · Vascular Diseases (2) · Arterial Occlusive Diseases (1) · Arteriosclerosis (1) · Autoimmune Diseases (1)
Echocardiography (2) · Exercise Test (2) · Hematologic Tests (2) · Blood Pressure Monitoring, Ambulatory (1) · Body Composition (1) · Body Mass Index (1) · Diagnostic Imaging (1) · Fenofibrate (1) · Losartan (1) · Perhexiline (1) · Physical Examination (1) · Positron-Emission Tomography (1) · Probiotics (1) · Resistance Training (1) · Sugars (1)
University of Texas Southwestern Medical Center (3) · Washington University School of Medicine (2) · Ain Shams University (1) · Applied Therapeutics, Inc. (1) · Assiut University (1) · Centre Hospitalier Universitaire de Nice (1) · Dongtan Sacred Heart Hospital (1) · Fondation Hôpital Saint-Joseph (1) · Hasselt University (1) · Heinrich-Heine University, Duesseldorf (1) · Hospices Civils de Lyon (1) · Imbria Pharmaceuticals, Inc. (1) · Institut National de la Santé Et de la Recherche Médicale, France (1) · Maastricht University Medical Center (1) · National Heart, Lung, and Blood Institute (NHLBI) (1)
United States (8) · France (6) · United Kingdom (6) · Germany (3) · Egypt (2) · Netherlands (2) · Spain (2) · Australia (1) · Belgium (1) · Brazil (1) · Canada (1) · China (1) · Czechia (1) · Denmark (1) · Hong Kong (1)
Amal K. Ahmed, Ass. Prof. (1) · Ambarish Pandey, MD, MSCS (1) · Andrea M Isidori, MD, PhD (1) · Arash Yavari, BSc, MBBS, DPhil (1) · Elric Zweck, MD (1) · Eun-Gyoung Hong, MD, PhD (1) · Gerry P McCann, MD (1) · Hany A. Muhammed Khalil, Lecturer (1) · Hun Jee Choe (1) · James L Januzzi, MD (1) · Jean E Schaffer, MD (1) · Linda R Peterson, MD (1) · Mahavir Singh, DVM, MS, PhD (1)
PMID 15035478, PMID 20157056, PMID 25780727, PMID 27845231, PMID 28567338, PMID 28579160, PMID 28661125, PMID 29192360, PMID 29205885, PMID 30832381, PMID 33417036, PMID 33623980, PMID 35038022, PMID 35299968, PMID 35643571, PMID 35704597, PMID 38302936, PMID 38597864, PMID 38986667, PMID 39095808, PMID 39806375, PMID 39814796, PMID 39882614, PMID 40315802, PMID 40338768, PMID 40403108, PMID 41410037, PMID 41663151, PMID 42538062, PMID 4263660
P20HL113444 (1)