135 completed, 30 unknown, 26 terminated, 19 recruiting. 60 Not applicable, 58 Phase 4, 49 Phase 1, 41 Phase 3, 38 Phase 2.
Follow Furosemide: new trials by email Literature Review of Furosemide trials Research Report on Furosemide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| ACetazolamide in Patients With Heart Failure, to Decrease Weight and relIEVE Symptoms. Acetazolamide, Furosemide - Heart Failure | Phase 3 | Not yet recruiting | University Hospital, Montpellier | 366 | 2026-10-01 | 2026-08-17 |
| Role of Postpartum Furosemide in Recovery of Patients With Severe Preeclampsia Furosemide and Potassium, Placebo - Severe Preeclampsia | Not applicable | Recruiting | Lady Reading Hospital, Pakistan | 434 | 2026-10-01 | 2026-10-06 |
| The Impact of Intraoperative Diuretic Use on Delayed Graft Function Following Deceased Donor Renal Transplantation Furosemide, Mannitol - Delayed Graft Function, Kidney Transplantation | Not applicable | Recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 160 | 2026-09-01 | 2026-09-18 |
| A Comparative Study of Normalized Residual Activity and Standard Parameters in 99mTc-DTPA Diuretic Renography: 99m Tc-DTPA, Furosemide - Urinary Tract Obstruction | Not yet recruiting | Assiut University | 57 | 2026-08-26 | 2026-09-10 | |
| Early Discharge With Subcutaneous Furosemide Versus Standard Care in Acute Heart Failure Early Discharge with Lasix® ONYU (furosemide injection, for subcutaneous use) using SQIN-Infusor - Heart Failure, Acute Decompensated Heart Failure | Phase 3 | Not yet recruiting | University of Texas Southwestern Medical Center | 250 | 2026-08-01 | 2026-05-04 |
| Contrast-Induced Acute Kidney Injury Prevention in Acute Heart Failure Furosemide, 0.9 % Normal Saline - Heart Failure Acute, Renal Dysfunction | Not applicable | Recruiting | Jin Joo Park | 190 | 2026-07-01 | 2026-07-16 |
| Optimizing Preeclampsia Postpartum With Point-of-care Ultrasound Butterfly iQ3 ultrasound system for determination of postpartum volume status, Oral furosemide, Intravenous furosemide - Preeclampsia, Preeclampsia Postpartum | Phase 4 | Not yet recruiting | University of California, Irvine | 96 | 2026-06-15 | 2026-01-23 |
| Furosemide vs Placebo in Severe Preeclampsia Postpartum Furosemide, Folic Acid 5 MG - Severe Preeclampsia | Phase 2 | Not yet recruiting | Universidad Nacional Autonoma de Honduras | 186 | 2026-06-15 | 2026-06-15 |
| Bumetanide vs. Furosemide in Cirrhosis Bumetanide, Furosemide - Cirrhosis | Phase 3 | Recruiting | Stacy Johnson | 500 | 2026-06-03 | 2026-06-16 |
| SURE-HF: Urinary Sodium-Guided Diuretic Therapy in Heart Failure Furosemide, Horiba LAQUAtwin B-722 - Worsening Heart Failure, Congestion | Not applicable | Not yet recruiting | Nurgul Ablakimova | 260 | 2026-06-01 | 2026-06-08 |
| Urine Sodium-Driven Diuretic Adjustment Strategy in Acute Decompensated Heart Failure Furosemide intravenous solution - Heart Failure, Heart Failure - NYHA II - IV | Phase 4 | Recruiting | Lakeland Regional Health Systems, Inc. | 600 | 2026-04-01 | 2026-04-09 |
| A Clinical Study of the Effect of MK-2828 on Rosuvastatin or Furosemide in Healthy People (MK-2828-005) Rosuvastatin, Furosemide, MK-2828 - Healthy | Phase 1 | Completed | Merck Sharp & Dohme LLC | 41 | 2026-03-18 | 2026-09-08 |
| Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite Athletes Testosterone Enanthate, Testosterone Cypionate, Testosterone Propionate - Safety and Impact of Medically Supervised Performance Enhancing Substance Usage in Healthy Elite Athletes | Not applicable | Enrolling by invitation | Enhanced Emirates Limited | 60 | 2026-03-12 | 2026-05-06 |
| Diuretic Effect of Aminophylline and Furosemide in Adult Patients Undergoing Cardiac Surgical Procedures Aminophylline, Furosemide - Diuretic Effect, Aminophylline | Not applicable | Recruiting | Cairo University | 106 | 2026-01-17 | 2026-01-21 |
| Impact of Forced Diuresis on the Residual Fragment Rate After Flexible Ureteroscopy for Management of Renal Stones Furosemide, Standard Care After Flexible Ureteroscopy Without Furosemide - Kidney Stones | Not applicable | Completed | Ain Shams University | 200 | 2026-01-01 | 2026-08-18 |
| Effect of HRS-8427 for Injection on the Pharmacokinetics of Furosemide and Metformin in Healthy Subjects。 HRS-8427 injection plus furosemide, HRS-8427 injection plus metformin - Health Volunteer | Phase 1 | Completed | Jiangsu HengRui Medicine Co., Ltd. | 24 | 2025-07-15 | 2025-08-28 |
| POCUS-Guided Diuresis for Decompensated Heart Failure Furosemide (Standard Diuretic) Treatment, POCUS-Assessed Diuretic Management - Heart Decompensation, Acute, Acute Kidney Injuries | Not applicable | Recruiting | University of Pittsburgh | 588 | 2025-06-29 | 2026-02-17 |
| "Effect of Albumin Combined With Furosemide in Critically Ill Patients With Fluid Overload: Impact on Urine Output and Renal Function" Furosemide plus albumin, Furosemide (Diuretic) - Urine Output Decreased | Not applicable | Recruiting | Jose J Zaragoza, MD MSc | 56 | 2025-06-01 | 2026-06-16 |
| Role of Intralesional Combined Injection of Furosemide and Digoxin in Cutaneous Warts at Tertiary Care Hospital in Karachi. Furosemide - Cutaneous Warts | Early Phase 1 | Enrolling by invitation | Jinnah Postgraduate Medical Centre | 40 | 2025-04-01 | 2025-02-12 |
| Modular Clinical Pharmacology Study to Evaluate the Drug-drug Interaction Potential and Relative Bioavailability of Saruparib Saruparib, Digoxin, Furosemide - Advanced Solid Malignancies | Phase 1 | Active not recruiting | AstraZeneca | 41 | 2025-03-25 | 2026-10-01 |
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Heart Failure (54) · Edema (19) · Hypertension (15) · Acute Kidney Injury (13) · Renal Insufficiency (10) · Dyspnea (9) · Renal Insufficiency, Chronic (9) · Pre-Eclampsia (7) · Critical Illness (6) · Diabetes Mellitus, Type 2 (6) · Hypertension, Pregnancy-Induced (6) · Fibrosis (5) · Ascites (4) · Diabetes Mellitus (4) · Kidney Calculi (4)
Boehringer Ingelheim (7) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (4) · University of Alberta (4) · Yale University (4) · Assistance Publique - Hôpitaux de Paris (3) · Assiut University (3) · AstraZeneca (3) · Duke University (3) · Hospital de Clinicas de Porto Alegre (3) · Mayo Clinic (3) · University of North Carolina, Chapel Hill (3) · University of Palermo (3) · scPharmaceuticals, Inc. (3) · Beth Israel Deaconess Medical Center (2) · Bristol-Myers Squibb (2)
United States (86) · Canada (20) · Germany (15) · France (13) · Italy (12) · United Kingdom (10) · Brazil (7) · China (6) · Egypt (6) · Netherlands (6) · Poland (6) · Spain (6) · Denmark (5) · Greece (4) · Israel (4)
Filippos Triposkiadis, MD (2) · Gregory Giamouzis, MD (2) · Jeffrey Testani, MD (2) · Adam P Bress, PharmD, MS (1) · Adhish Agarwal, MD (1) · Adrian Hernandez, MD (1) · Aharon Abbo, MD (1) · Alain Mina, M.D. (1) · Alfonso Castro Beiras, MD, PhD (1) · Alicja Rydzewska-Rosolowska, MD (1)
PMID 39878152, PMID 24053972, PMID 26240596, PMID 21440872, PMID 22980301, PMID 39196651, PMID 10961490, PMID 10961491, PMID 11232182, PMID 11818776, PMID 12473535, PMID 12479763, PMID 12660656, PMID 12873814, PMID 12973821, PMID 15106785, PMID 15196097, PMID 15531475, PMID 15963399, PMID 16474108, PMID 17093067, PMID 17122580, PMID 17172977, PMID 17511554, PMID 17973110, PMID 18073543, PMID 18322044, PMID 18391085, PMID 18450135, PMID 18539917, PMID 19114909, PMID 19535188, PMID 19570764, PMID 19602136, PMID 19673667, PMID 19806461, PMID 19898642, PMID 20061358, PMID 20061360, PMID 20123766, PMID 20215456, PMID 20228401, PMID 20228404, PMID 20346637, PMID 20427682, PMID 20459801, PMID 20571135, PMID 20587587, PMID 20594588, PMID 20607462
2014 (4), 2015 (3), 2018 (3), 2016 (2), 2017 (2), 2019 (2), R01NR012009 (2), UL1TR000135 (2), 1IK2CX002368-01A1 (1), 2008 (1), 2025 (1), N01HC95178 (1), N01HC95179 (1), N01HC95180 (1), N01HC95181 (1)