39 completed, 18 recruiting, 11 unknown, 6 terminated. 31 Not applicable, 11 Phase 1, 8 Phase 4, 3 Early Phase 1, 2 Phase 2.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Impact of Epilepsy on the Brainstem Adenosine Pathway and Its Relation With Arousal and Respiratory Reactivity 1 Hypercapnic challenge while participant is awake, PET/MRI acquisition - Epilepsy, Drug-resistant Focal Epilepsy | Not applicable | Recruiting | Hospices Civils de Lyon | 50 | 2026-10-01 | 2026-10-07 |
| Safety and Tolerability Study of VVZ-2471 in Healthy Volunteers Placebo pills for 14-day intervention, VVZ-2471 for 14-day intervention - Healthy Controls | Phase 1 | Recruiting | Virginia Commonwealth University | 60 | 2026-08-28 | 2026-09-01 |
| Development of Eye-movement Based Biomarkers in Alzheimer's Disease Eye-Tracking - Alzheimer's Disease, Healthy Controls | Recruiting | McGill University | 250 | 2026-05-19 | 2026-10-14 | |
| A PET-MRI Study of Serotoninergic Brainstem Pathway in Patients With Dravet Syndrome [18F]MPPF PET-MRI - Epilepsy, Dravet Syndrome | Not applicable | Recruiting | Hospices Civils de Lyon | 30 | 2026-05-04 | 2026-05-08 |
| Acute Effect of Graded Motor Imagery on Ankle Rehabilitation: A Pilot Study graded motor imagery - Ankle Instability, Healthy Controls | Not applicable | Recruiting | Istanbul University - Cerrahpasa | 48 | 2026-02-09 | 2026-02-11 |
| Subthreshold Vestibular Stimulation as a Strategy for Rehabilitation Subthreshold Vestibular Conditioning, Balance Training, Balance Training Plus Subthreshold Conditioning - Vestibular Hypofunction, Bilateral Vestibular Hypofunction | Not applicable | Recruiting | Creighton University | 48 | 2026-02-09 | 2026-03-17 |
| Do Antipsychotics Block Insulin Action in the Brain: is it a Class Effect? Haloperidol, Placebo, Insulin Lispro - Brain Insulin Sensitivity, Healthy Controls | Phase 4 | Recruiting | Centre for Addiction and Mental Health | 35 | 2025-12-11 | 2026-04-02 |
| Elucidating the Role of Cholinergic Degeneration in Cognitive Fluctuations in Lewy Body Dementia Syn-One skin biopsy, Multi modal MRI, Assessment of dynamic EEG features over 48-hour periods across all study aims - Dementia With Lewy Bodies, Parkinson Disease Dementia | Phase 4 | Recruiting | Virginia Commonwealth University | 120 | 2025-12-08 | 2026-03-06 |
| Metabolic Characterization of Alzheimer's Disease and Frontotemporal Dementia by 23Na-MRI and FDG-PET Sodium MRI - FTD, AD | Not applicable | Not yet recruiting | Centre Hospitalier St Anne | 55 | 2025-10-01 | 2025-08-03 |
| Physical and Psychosocial Parameters in Takayasu Arteritis and Behçet's Disease: A Comparative Study With Healthy Controls No intervention (observational study) - Takayasu Arteritis, Behçet's Disease | Recruiting | ÖZLEM NUR TOK YAMAN | 30 | 2025-09-11 | 2025-12-10 | |
| Pilot Study of Personalized Aperiodic Transcranial Alternating Current Stimulation in Antenatal Depression (PandA-tACS) tACS (aperiodic) - Antenatal Depression, Major Depressive Disorder | Not applicable | Terminated | University of North Carolina, Chapel Hill | 6 | 2025-08-12 | 2026-09-28 |
| Mass Spectrometry-based Immune Profiling in Autoimmune Diseases Systemic Lupus Erthematosus, Sjogren's Syndrome | Enrolling by invitation | Peking University People's Hospital | 500 | 2025-05-25 | 2026-08-26 | |
| Dose-Dependent Effects of Low-Intensity Focused Ultrasound Low-intensity focused ultrasound - Healthy Controls | Not applicable | Recruiting | Laureate Institute for Brain Research, Inc. | 66 | 2025-04-22 | 2025-10-16 |
| Temporal Interference Stimulation for Social Cognition Transcranial Interference Stimulation (tIS), Sham tIS - Healthy Controls | Not applicable | Recruiting | Columbia University | 10 | 2025-03-03 | 2026-04-23 |
| Artificial Intelligence Literacy and E-Health Literacy in Rheumatic Diseases Rheumatoid Arthritis, Ankylosing Spondylitis | Completed | Gulseren Demir Karakilic | 201 | 2024-12-22 | 2025-07-14 | |
| Development of Digital Services for Parkinson's Disease gait with cueing wearable device and neuro-ocular performance - Healthy Controls, Parkinson's Disease | Not applicable | Recruiting | University of Exeter | 80 | 2024-12-20 | 2025-02-03 |
| Gait Profile and Variables in Pediatric Rheumatic Disease Using a Smart Insole System Juvenile Idiopathic Arthritis (JIA), Familial Mediterranean Fever (FMF ) | Not yet recruiting | Istanbul University - Cerrahpasa | 60 | 2024-12-02 | 2024-11-26 | |
| Plasticizer Exposure and Its Consequences on Health Beta-thalassemia, Glioma | Not yet recruiting | Medical University of Vienna | 120 | 2024-10-01 | 2024-07-24 | |
| Healthy Control Population for PAIS-ME/CFS: Study to Evaluate Possible Biomarkers and Methods for Examination of PAIS-ME/CFS Diagnostics in Healthy Volunteers Diagnostic Test - Healthy Controls | Not yet recruiting | Technical University of Munich | 200 | 2024-10-01 | 2024-10-22 | |
| NeuroCatch Reference Interval Database NeuroCatch® Platform 2 - Healthy Controls, Brain Function | Not applicable | Terminated | HealthTech Connex Inc. | 224 | 2024-08-05 | 2026-09-22 |
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Alzheimer Disease (4) · Arthritis, Rheumatoid (4) · Multiple Sclerosis (4) · Parkinson Disease (4) · Arthritis, Psoriatic (3) · Cognitive Dysfunction (3) · Depression (3) · Depressive Disorder (3) · Depressive Disorder, Major (3) · Lewy Body Disease (3) · Motor Activity (3) · Attention Deficit Disorder with Hyperactivity (2) · Bipolar Disorder (2) · Colitis, Ulcerative (2) · Crohn Disease (2)
Nervous System Diseases (23) · Mental Disorders (20) · Central Nervous System Diseases (15) · Pathological Conditions, Signs and Symptoms (15) · Brain Diseases (13) · Immune System Diseases (11) · Autoimmune Diseases (9) · Musculoskeletal Diseases (9) · Neurodegenerative Diseases (9) · Pathologic Processes (9) · Neurocognitive Disorders (7) · Skin and Connective Tissue Diseases (7) · Arthritis (6) · Basal Ganglia Diseases (6) · Behavior (6)
Sodium Chloride (4) · Blood Specimen Collection (3) · Escitalopram (2) · Ketamine (2) · Magnetic Resonance Spectroscopy (2) · Restraint, Physical (2) · Surveys and Questionnaires (2) · 1-((3-(methylpyridin-4-yl)methyl)-4-(3,4,5-trifluorophenyl)pyrrolidin-2-one (1) · 2-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole (1) · 23-valent pneumococcal capsular polysaccharide vaccine (1) · 6-(3-fluoropropyl)-3-(2-(azepan-1-yl)ethyl)benzo(d)thiazol-2(3H)-one (1) · 6-chloro-2-(4'-iodophenyl)-3-(N,N-diethyl)imidazo(1,2-a)pyridine-3-acetamide (1) · Acetazolamide (1) · Atorvastatin (1) · Blood Pressure Monitors (1)
Centre for Addiction and Mental Health (3) · ElMindA Ltd (3) · Hospices Civils de Lyon (3) · Massachusetts General Hospital (3) · Virginia Commonwealth University (3) · Bert Op't Eijnde (2) · Children's Hospital Los Angeles (2) · Istanbul University - Cerrahpasa (2) · Johns Hopkins University (2) · New York State Psychiatric Institute (2) · University of North Carolina, Chapel Hill (2) · Yale University (2) · Assistance Publique - Hôpitaux de Paris (1) · Beth Israel Deaconess Medical Center (1) · Centre Hospitalier St Anne (1)
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Jeffrey A Lieberman, MD (2) · Anja Hviid Simonsen, MSc Pharm PhD (1) · Arno Villringer (1) · Asena Yekdaneh, MSc (1) · Ashley Woodcock, Prof (1) · Asya Albayrak, MSc (1) · Barbara L Peterlin, DO (1) · Bert O Eijnde, Ph.D. (1) · Bert Opt Eijnde, Ph.D (1) · Boadie W Dunlop, MD (1) · Bradley D. Vince, D.O. (1) · Brian P Brennan, MD (1)
PMID 25264868, PMID 25409110, PMID 25666356, PMID 25833970, PMID 26418222, PMID 26847016, PMID 27084281, PMID 28228504, PMID 28522096, PMID 29167877, PMID 29228942, PMID 29975012, PMID 30686636, PMID 33242662, PMID 33325531, PMID 34273558, PMID 34778701, PMID 35302402, PMID 35709648, PMID 36229188, PMID 36441736, PMID 37238713, PMID 37291448, PMID 37851412, PMID 39375781, PMID 39487320, PMID 39838483, PMID 41225647, PMID 41330694, PMID 41681461, PMID 41866024, PMID 42015271, PMID 42797541
1RC1ES018417 (1), 1UG3DA063353 (1), 2016 (1), 2018 (1), 271201200007I-4-27100003-2 (1), R00DC020759 (1), R01DA052454 (1), R01HL136484 (1), R01MH111448 (1), R01NS142622 (1), U01MH135436 (1), U54DA038999 (1)