8357 completed, 2079 unknown, 1838 recruiting, 1016 terminated. 4157 Not applicable, 2692 Phase 2, 1875 Phase 3, 1739 Phase 1, 1040 Phase 4.
Follow Autoimmune Diseases: new trials by email Literature Review of Autoimmune Diseases trials Research Report on Autoimmune Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of Vigorous Versus Low Intensity Cool Room Treadmill Training in People with Multiple Sclerosis Body-weight supported treadmill training in a room cooled to 16°C - Multiple Sclerosis, Neurological Rehabilitation | Not applicable | Withdrawn | Memorial University of Newfoundland | 2030-01-01 | 2024-11-27 | |
| Cannabichromene Safety in Rheumatoid Arthritis Cannabichromene - Arthritis, Rheumatoid | Phase 1 / Phase 2 | Withdrawn | Crystal Lederhos Smith | 2028-07-15 | 2026-09-23 | |
| Study of NM8074 in Patients With Immunoglobulin A Nephropathy (IgAN) NM8074 - IgA Nephropathy | Phase 2 | Not yet recruiting | NovelMed Therapeutics | 10 | 2028-02-01 | 2026-04-13 |
| Insul-In This Together: Leveraging Family Support and Diabetes Technology for Adolescents Living With Type 1 Diabetes Insul-In This Together - Diabetes Type 1 | Not applicable | Not yet recruiting | Stanford University | 200 | 2028-01-01 | 2026-10-05 |
| An Open-label Study of GC012F in Rheumatoid Arthritis. LD and GC012F CAR-T Cell Injection, GC012F CAR-T Cell Injection - Rheumatoid Arthritis | Early Phase 1 | Withdrawn | Institute of Hematology & Blood Diseases Hospital, China | 2027-12-01 | 2026-06-10 | |
| CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy, in Patients With Refractory Systemic Lupus Erythematosus (GALLOP) CB-010 - Systemic Lupus Erythematosus, Lupus | Phase 1 | Withdrawn | Caribou Biosciences, Inc. | 2027-12-01 | 2025-09-19 | |
| Inductive Therapeutic Exercise in Multiple Sclerosis Experimental: Inductive Therapeutic Exercise (ETI), Control: Sham Inductive Therapeutic Exercise (sham-ETI) - Multiple Sclerosis | Not applicable | Not yet recruiting | Fundación San Juan De Dios | 30 | 2027-10-01 | 2026-10-02 |
| Aspirin for the Prevention of Ischemic Complications in Giant Cell Arteritis Acetyl Salicylic Acid (ASA), Placebo - Giant Cell Arteritis (GCA), Acute Coronary Syndrome (ACS) | Phase 3 | Not yet recruiting | Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal | 120 | 2027-10-01 | 2026-10-30 |
| GLP-1 RA for Stage 1 Type 1 Diabetes Semaglutide, Placebo - Stage 1 Diabetes Mellitus, Type 1 | Phase 2 | Not yet recruiting | Children's Hospital Medical Center, Cincinnati | 15 | 2027-09-01 | 2026-02-24 |
| A Clinical Study Evaluating the Safety and Efficacy of GT719 Universal Cell Injection in the Treatment of Immune-mediated Kidney Diseases CD19-targeted iNKT Cell Injection - IgA Nephropathy (IgAN), Membranous Nephropathy | Early Phase 1 | Not yet recruiting | Grit Biotechnology | 30 | 2027-08-01 | 2026-09-11 |
| Open-Label Extension Study of MHB018A in Patients With Thyroid Eye Disease MHB018A injection - Thyroid Eye Disease (TED) | Phase 3 | Not yet recruiting | Minghui Pharmaceutical (Hangzhou) Ltd | 219 | 2027-07-01 | 2026-06-04 |
| Autoimmune Disease Treatment With Mesenchymal Stem Cells (MSCs) and CAR-T Cells fetal MSCs combined with 4SCAR T cells - Autoimmune Diseases | Phase 1 / Phase 2 | Not yet recruiting | Shenzhen Geno-Immune Medical Institute | 30 | 2027-06-30 | 2026-11-02 |
| Exploring Reproductive Decision-Making Among Women With Multiple Sclerosis Multiple Sclerosis | Not yet recruiting | Assiut University | 272 | 2027-06-01 | 2026-09-21 | |
| CAR-T Cells Targeting Autoimmune Diseases 4SCAR T cells - Autoimmune Diseases | Phase 1 / Phase 2 | Not yet recruiting | Shenzhen Geno-Immune Medical Institute | 30 | 2027-06-01 | 2026-11-02 |
| A Study to Learn About How Well the Medicine Efgartigimod Works to Treat Autoimmune Encephalitis In Children 12 Years or Older and Adults Efgartigimod PH20 (ARGX-113) SC, Placebo PH20 SC - Autoimmune Encephalitis (AE) | Phase 2 | Not yet recruiting | argenx | 170 | 2027-04-01 | 2026-09-22 |
| CKM For Safe Use of SGLT2i in Type 1 Diabetes Sotagliflozin Low Dose, Sotagliflozin High Dose, Dual Continuous Glucose and Ketone Monitor - Type 1 Diabetes (T1D) | Phase 3 | Not yet recruiting | University of California, San Diego | 52 | 2027-04-01 | 2026-11-04 |
| Quantification of Change in MG Disease Activity in Individuals With Generalized Myasthenia Gravis (gMG) After Administration of VYVGART® or VYVGART Hytrulo® Using BioDigit MG Myasthenia Gravis Generalized | Not yet recruiting | BioSensics | 25 | 2027-03-15 | 2026-10-13 | |
| A Study of Remibrutinib Using MR Imaging in Relapsing or Progressive MS Remibrutinib (Open Label) - Multiple Sclerosis (MS) - Relapsing-remitting, Multiple Sclerosis (MS) Secondary Progressive | Phase 2 | Not yet recruiting | Moein Amin | 20 | 2027-03-01 | 2026-08-19 |
| C-CAR168, an Autologous Anti-CD20/BCMA Chimeric Antigen Receptor T-Cell Therapy, in Participants With Systemic Sclerosis (SSc) Refractory to Standard Therapy C-CAR168 - Systemic Sclerosis (SSc), Systemic Sclerosis | Phase 1 | Not yet recruiting | AbelZeta Inc. | 12 | 2027-03-01 | 2026-10-13 |
| A Study of Ianalumab in Addition to Eltrombopag in Pediatric Patients With Primary ITP Who Failed Corticosteroids. Ianalumab, Eltrombopag - Primary Immune Thrombocytopenia (ITP) | Phase 2 | Not yet recruiting | Novartis Pharmaceuticals | 36 | 2027-02-08 | 2026-06-25 |
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Diabetes Mellitus, Type 1 (3571) · Arthritis, Rheumatoid (3287) · Multiple Sclerosis (3156) · Lupus Erythematosus, Systemic (1184) · Diabetes Mellitus (774) · Multiple Sclerosis, Relapsing-Remitting (615) · Purpura, Thrombocytopenic, Idiopathic (482) · Diabetes Mellitus, Type 2 (454) · Motor Activity (391) · Arthritis, Juvenile (359) · Lupus Nephritis (333) · Sjogren's Syndrome (322) · Myasthenia Gravis (320) · Arthritis (286)
Immune System Diseases (15162) · Skin and Connective Tissue Diseases (5719) · Connective Tissue Diseases (5141) · Nervous System Diseases (4788) · Autoimmune Diseases of the Nervous System (4336) · Musculoskeletal Diseases (4160) · Endocrine System Diseases (4057) · Joint Diseases (3887) · Rheumatic Diseases (3870) · Nutritional and Metabolic Diseases (3829) · Demyelinating Diseases (3826) · Metabolic Diseases (3753) · Demyelinating Autoimmune Diseases, CNS (3672) · Arthritis (3664)
Methotrexate (331) · Rituximab (302) · tocilizumab (214) · Blood Specimen Collection (180) · Adalimumab (174) · Etanercept (170) · Insulin Aspart (168) · Prednisone (168) · Cyclophosphamide (148) · Exercise (140) · Mycophenolic Acid (137) · Abatacept (127) · Methylprednisolone (127) · Insulin (120) · Insulin Glargine (116)
Hoffmann-La Roche (279) · Novo Nordisk A/S (241) · Novartis Pharmaceuticals (217) · Assiut University (194) · Biogen (192) · Assistance Publique - Hôpitaux de Paris (161) · Pfizer (150) · Amgen (141) · Sanofi (139) · GlaxoSmithKline (135) · Eli Lilly and Company (129) · Bristol-Myers Squibb (125) · AstraZeneca (102) · National Institute of Allergy and Infectious Diseases (NIAID) (100) · University of Colorado, Denver (83)
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PMID 33687069, PMID 38299639, PMID 36600185, PMID 36601090, PMID 36931693, PMID 36526796, PMID 32816215, PMID 33127856, PMID 34870800, PMID 28143815, PMID 39192350, PMID 25047021, PMID 27338778, PMID 34778952, PMID 38958913, PMID 29244149, PMID 30649524, PMID 37453736, PMID 39735417, PMID 26275429, PMID 33263165, PMID 34706874, PMID 37528520, PMID 40465397, PMID 29463520, PMID 34041702, PMID 34628605, PMID 34741731, PMID 38864363, PMID 26032537, PMID 31072380, PMID 31610021, PMID 36205910, PMID 37747626, PMID 19005182, PMID 21387374, PMID 28205039, PMID 28941219, PMID 30177460, PMID 33023488, PMID 34531304, PMID 35577477, PMID 36715850, PMID 36754548, PMID 36814062, PMID 37308218, PMID 37945286, PMID 37982966, PMID 38775637, PMID 40875187
2023 (120), 2015 (83), 2025 (83), 2014 (78), 2018 (74), 2009 (73), 2017 (70), 2019 (66), 2016 (65), 2008 (48), 2005 (21), 2004 (13), U54AR057319 (8), R01DK085623 (7), UC4DK117009 (7)