92 completed. 92 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 92 | Completed 92 |
Follow Epilepsy: new trials by email Literature Review of Epilepsy trials Research Report on Epilepsy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pro-Epileptic Effects of IV Ketamine Ketamine, Midazolam, Propofol - Epilepsy, Seizure | Phase 4 | Completed | Haseki Training and Research Hospital | 300 | 2024-12-01 | 2025-12-15 |
| Brain Regions and Functional Neuronal Network Characteristics of Dexmedetomidine Analgesia Dexmedetomidine Injectable Solution, Sodium Chloride 0.9% Inj - Epilepsy, Radiofrequency Ablation | Phase 4 | Completed | China International Neuroscience Institution | 28 | 2024-01-15 | 2026-09-10 |
| Evaluation of Levetiracetam's Effectiveness and Tolerability for Treating Epilepsy in Older Adults Oral levetiracetam - Epilepsy, Elderly | Phase 4 | Completed | Nasim Tabrizi | 137 | 2023-09-13 | 2026-02-19 |
| Fenfluramine for the Treatment of Different Types of Developmental and Epileptic Encephalopathies: a Pilot Trial Exploring Epileptic and Non-epileptic Outcomes Fenfluramine - Refractory Epilepsy, SYNGAP1 Encephalopathy | Phase 4 | Completed | Hospital Ruber Internacional | 20 | 2022-10-20 | 2026-09-29 |
| A Study to Evaluate the Efficacy and Safety of Perampanel Monotherapy in Untreated Participants With Focal Onset Seizures With or Without Focal to Bilateral Tonic-clonic Seizures Perampanel - Epilepsy | Phase 4 | Completed | Eisai Korea Inc. | 125 | 2022-10-19 | 2025-03-07 |
| Epidiolex® for Anxiety in Pediatric Epilepsy Cannabidiol 100 MG/ML - Anxiety, Epilepsy | Phase 4 | Completed | Hugo W. Moser Research Institute at Kennedy Krieger, Inc. | 20 | 2022-04-05 | 2025-07-02 |
| Effects of Diazepam on RNS Detections nasal diazepam - Epilepsies, Partial | Phase 4 | Completed | University of Cincinnati | 4 | 2022-03-01 | 2024-04-12 |
| Low vs. Standard Daily Doses of Antiepileptic Drugs in Newly Diagnosed, Previously Untreated Epilepsy(STANDLOW) Low dose carbamazepine, Standard dose carbamazepine, Low dose levetiracetam - Epilepsies, Partial | Phase 4 | Completed | Mario Negri Institute for Pharmacological Research | 58 | 2021-05-10 | 2025-07-08 |
| Probiotic in Treatment of Adult Patients With Drug-resistant Epilepsy Probiotic - Epilepsy, Treatment | Phase 4 | Completed | Mazandaran University of Medical Sciences | 42 | 2021-04-21 | 2022-01-11 |
| Fenfluramine and Cognition Fenfluramine, Placebo - Cognitive Function | Phase 4 | Completed | University of Oxford | 56 | 2021-04-12 | 2022-11-15 |
| Effect of Pyridoxine on Behavioral Adverse Events of Levetiracetam Pyridoxine, Placebo - Epilepsy, Pyridoxine | Phase 4 | Completed | Nasim Tabrizi | 30 | 2020-10-01 | 2022-03-29 |
| Effect of Melatonin on Seizure Outcome, Neuronal Damage and Quality of Life in Patients With Generalized Epilepsy Melatonin 3 mg, Placebo - Generalized Epilepsy | Phase 4 | Completed | All India Institute of Medical Sciences, Bhubaneswar | 104 | 2018-08-06 | 2020-09-03 |
| Efficacy and Safety of Rapid Titration Protocols of Lacosamide Lacosamide - conventional titration, Lacosamide - rapid titration 1, Lacosamide - rapid titration 2 - Focal Epilepsy | Phase 4 | Completed | Seoul National University Hospital | 75 | 2018-08-03 | 2020-02-18 |
| Anxiety and Depression in Epilepsy: A Treatment Study Escitalopram 10mg, Referral to Psychiatry, Survey only - Anxiety, Depression | Phase 4 | Completed | Wake Forest University Health Sciences | 69 | 2018-05-07 | 2020-10-19 |
| Fycompa Titration Intervals and Effects on Retention Rate Perampanel Oral Tablet - Epilepsy | Phase 4 | Completed | University of Arizona | 20 | 2018-04-18 | 2023-08-15 |
| Dexmedetomidine and Propofol for Pediatric MRI Sedation propofol, Dexmedetomidine, Glycopyrrolate - Headache, Tumor | Phase 4 | Completed | Medical College of Wisconsin | 40 | 2018-03-04 | 2020-02-21 |
| Pharmacokinetics of Two Formulation of Pregabalin Pregabalin - Diabetic Peripheral Neuropathy, Fibromyalgia | Phase 4 | Completed | Yung Shin Pharm. Ind. Co., Ltd. | 28 | 2018-01-19 | 2019-01-28 |
| Ivermectin Treatment in Patients With Onchocerciasis-associated Epilepsy Ivermectin - Ivermectin, Onchocerciasis | Phase 4 | Completed | Robert Colebunders | 91 | 2017-10-01 | 2019-01-07 |
| Use of Clobazam for Epilepsy and Anxiety Clobazam - Epilepsy, Anxiety | Phase 4 | Completed | Hugo W. Moser Research Institute at Kennedy Krieger, Inc. | 20 | 2017-10-01 | 2021-03-04 |
| Ivermectin Treatment of Persons With Onchocerciasis-associated Epilepsy ivermectin - Epilepsy | Phase 4 | Completed | Universiteit Antwerpen | 197 | 2017-10-01 | 2019-09-26 |
Showing 20 of 92. Sign in to see all of them.
Seizures (20) · Epilepsies, Partial (19) · Nervous System Diseases (5) · Anxiety Disorders (3) · Attention Deficit Disorder with Hyperactivity (2) · Brain Diseases (2) · Brain Neoplasms (2) · Depression (2) · Depressive Disorder, Major (2) · Epilepsy, Generalized (2) · Epilepsy, Rolandic (2) · Epilepsy, Tonic-Clonic (2) · Headache (2) · Learning Disabilities (2)
Central Nervous System Diseases (91) · Brain Diseases (90) · Nervous System Diseases (87) · Pathological Conditions, Signs and Symptoms (25) · Signs and Symptoms (24) · Neurologic Manifestations (23) · Mental Disorders (11) · Epileptic Syndromes (6) · Epilepsy, Generalized (4) · Neurodevelopmental Disorders (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Epilepsies, Partial (3) · Neoplasms by Site (3) · Attention Deficit and Disruptive Behavior Disorders (2)
Levetiracetam (18) · Lamotrigine (10) · Zonisamide (9) · Carbamazepine (7) · Topiramate (7) · Lacosamide (5) · Pregabalin (5) · Valproic Acid (5) · Gabapentin (4) · Oxcarbazepine (4) · Phenytoin (3) · perampanel (3) · Dexmedetomidine (2) · Escitalopram (2) · Fenfluramine (2)
UCB Pharma (9) · Eisai Korea Inc. (6) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (4) · GlaxoSmithKline (3) · University of Cincinnati (3) · Eisai Limited (2) · Hugo W. Moser Research Institute at Kennedy Krieger, Inc. (2) · Nasim Tabrizi (2) · Novartis (2) · University of Maryland, Baltimore (2) · Yonsei University (2) · All India Institute of Medical Sciences, Bhubaneswar (1) · Boston Children's Hospital (1) · Boston VA Research Institute, Inc. (1) · Children's National Research Institute (1)
United States (35) · South Korea (13) · France (4) · Germany (4) · Italy (4) · Austria (3) · Iran (3) · Russia (3) · Spain (3) · United Kingdom (3) · Bulgaria (2) · Czechia (2) · Democratic Republic of the Congo (2) · Denmark (2) · Finland (2)
Jihee Mun (4) · Kimford Meador, MD (2) · Michel J Berg, MD (2) · Alex Bekker, MD, PhD (1) · Andrew Yeates (1) · Anne Davis, MD (1) · Antonio A Lazzari, MD (1) · Antonio Gil-Nagel, MD, PHD (1) · Bassel Abou-Khalil, MD (1) · Byung-In Lee (1) · Carol Lippa, MD (1)
PMID 10208286, PMID 11117539, PMID 11137386, PMID 11976067, PMID 15069466, PMID 15145300, PMID 15521903, PMID 15652736, PMID 15794175, PMID 16344515, PMID 16406488, PMID 16524783, PMID 16674605, PMID 17300358, PMID 17681453, PMID 17826314, PMID 17851135, PMID 17888078, PMID 18456557, PMID 1947597, PMID 19682955, PMID 20462804, PMID 20685215, PMID 21352847, PMID 21454134, PMID 21909835, PMID 22378657, PMID 22658946, PMID 23435277, PMID 24314750, PMID 24403284, PMID 24655096, PMID 25616485, PMID 25684224, PMID 25948717, PMID 26216692, PMID 26425001, PMID 26514204, PMID 26875743, PMID 27199889, PMID 27315132, PMID 27513702, PMID 27521437, PMID 28031390, PMID 28214985, PMID 28276064, PMID 28395124, PMID 28460319, PMID 28597842, PMID 28654954
2009 (2), 2005 (1), 2014 (1), 5UL1TR001420-03 (1), K23MH066835 (1), M01RR000069 (1), R49CE721682 (1)