1057 completed. 1057 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 1057 | Completed 1057 |
Follow Depressive Disorder: new trials by email Literature Review of Depressive Disorder trials Research Report on Depressive Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Stereotactic Radiotherapy Treatment for Treatment-Resistant Depression ZAP-X - Treatment-Resistant Depression, Depressive Disorder | Not applicable | Completed | Capital Medical University | 9 | 2026-01-26 | 2026-08-10 |
| The Effect of Psychodramatic Role-Playing on Postpartum Depression, Self-Efficacy, and Perceived Social Support Psychodramatic Role-Playing Childbirth Education, Standard Childbirth Education - Postpartum Depression, Maternal Self-Efficacy | Not applicable | Completed | Istanbul University - Cerrahpasa | 57 | 2025-10-31 | 2026-04-02 |
| Effectiveness of Traditional Chinese Metacognitive Training (MCT) in Patients With Schizophrenia, Depression, or Bipolar Disorder Attending a Psychiatric Day Hospital in Taiwan Metacognitive Training (MCT), Traditional Chinese version - Schizophrenia, Major Depressive Disorder | Not applicable | Completed | ZI-YU LIN | 18 | 2025-10-03 | 2025-12-10 |
| Pilot Study of Brief Culturally Adapted Behavioral Activation for Adults With Depression in Primary Care Setting brief culturally adapted behavioral activation - Depression in Adults | Not applicable | Completed | Gadjah Mada University | 12 | 2025-09-22 | 2026-07-21 |
| REM Sleep Disruption and Its Potential Uses in Depression Management REM-Contingent Smartwatch Haptic Stimulation, Smartwatch Sleep Monitoring and Smart Alarm - Depression / Major Depressive Disorder, Depressed Mood | Not applicable | Completed | WAKEZ HEALTH TECH ECOSYSTEM SRL | 208 | 2025-09-01 | 2026-10-23 |
| Fermented Milk Drink With Lacticaseibacillus Paracasei Strain Shirota Helps Triathletes With Cold-Like Symptoms Before and After a Race Intervention Name: Fermented milk containing Lacticaseibacillus paracasei strain Shirota. Intervention Name: Non-fermented milk (placebo), Non-fermented milk (placebo) - Respiratory Tract Infections (RTI), Mucosal Immunity | Not applicable | Completed | Federal University of São Paulo | 80 | 2025-08-13 | 2026-10-15 |
| Optimizing a Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents ViraBrite nudges - Suicide, Mental Health Disorder | Not applicable | Completed | Ksana Health | 24 | 2025-07-16 | 2026-08-12 |
| Virtual Reality-Based Psychotherapeutic and Psychoeducational Intervention for Anxiety and Depression in Children, Adolescents, and Adults Virtual Reality-Based Psychotherapeutic Program - Anxiety Disorders, Depressive Disorders | Not applicable | Completed | Istanbul Aydın University | 40 | 2025-07-09 | 2025-11-26 |
| The Effect of Yoga Applied to Primiparous Pregnant Women on Postpartum Depression and Maternal Attachment prenatal yoga - Depression, Postpartum | Not applicable | Completed | Muş Alparslan University | 80 | 2025-07-07 | 2026-10-20 |
| Psychoeducational Intervention to Reduce Depressive Symptoms and Strengthen Mother-Infant Bonding the psychoeducation intervention program, routine care - Postpartum Depression, Psychoeducation | Not applicable | Completed | Yasemin Ozhuner | 88 | 2025-07-02 | 2026-01-07 |
| Comparison of Propofol and Ketofol as Induction Agents for Electroconvulsive Therapy Propofol, Ketofol - Major Depressive Disorder | Not applicable | Completed | Fauji Foundation Hospital | 80 | 2025-07-01 | 2025-12-12 |
| Electroconvulsive Therapy Versus Intravenous Ketamine in Treatment-Resistant Major Depressive Disorder Electroconvulsive Therapy, Ketamine - Electroconvulsive Therapy, Intravenous Ketamine | Not applicable | Completed | Tanta University | 70 | 2025-07-01 | 2026-04-13 |
| Magnesium Supplementation With Fluoxetine for Cognitive Function in Depression Fluoxetine (drug), Magnesium - Major Depressive Disorder (MDD) | Not applicable | Completed | Hasanuddin University | 40 | 2025-07-01 | 2026-04-09 |
| The Brain-Heart-Gut Connection Transcranial Magnetic Stimulation (TMS), High-definition transcranial direct current stimulation (HD-tDCS) - Major Depression, Functional Dyspepsia | Not applicable | Completed | University of Bern | 34 | 2025-06-01 | 2026-04-08 |
| 6 Weeks Right-Amygdala TIS for Depression Nervio-X - Major Depressive Disorder (MDD) | Not applicable | Completed | Ruijin Hospital | 38 | 2025-05-27 | 2026-07-09 |
| Problem Management Plus (PM+) in Chile: a Pilot Randomized Controlled Trial of a Psychological Transdiagnostic Intervention Delivered in Primary Health Care Problem Management Plus (PM+) - Anxiety Disorders, Depressive Disorder | Not applicable | Completed | University of Chile | 56 | 2025-05-09 | 2025-11-20 |
| Efficacy of Dextromethorphan-Bupropion Versus SSRIs in the Treatment of Major Depressive Disorder Dextromethorphan-Bupropion, SSRIs - Major Depressive Disorder (MDD) | Not applicable | Completed | Asad Ullah Jan | 80 | 2025-05-06 | 2026-05-07 |
| Individualized Non-invasive Brain Stimulation for the Treatment of Major Depressive Disorder Closed-loop tACS, Sham Comparator - Depression - Major Depressive Disorder, Transcranial Alternating Current Stimulation | Not applicable | Completed | Pulvinar Neuro, LLC | 40 | 2025-04-11 | 2026-08-18 |
| The Effect of Psychodrama-Based Group Work psychodrama-based group intervention, Control - Psychiatric Nursing, Depression Disorder | Not applicable | Completed | Ömer USLU | 23 | 2025-04-02 | 2026-01-06 |
| Enhancing Depression Literacy and Reducing Stigma in Adolescents Through Social Media "ich bin alles", Instagram profile that provides educational content - Depressive Disorder, Depression - Major Depressive Disorder | Not applicable | Completed | Ludwig-Maximilians - University of Munich | 170 | 2025-04-01 | 2025-12-04 |
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Depressive Disorder, Major (611) · Depression (355) · Depression, Postpartum (216) · Anxiety Disorders (128) · Bipolar Disorder (90) · Depressive Disorder, Treatment-Resistant (65) · Schizophrenia (60) · Mood Disorders (45) · Mental Disorders (41) · Stress Disorders, Post-Traumatic (38) · Psychological Well-Being (34) · Psychotic Disorders (31) · Generalized Anxiety Disorder (24) · Motor Activity (23)
Mental Disorders (1016) · Mood Disorders (1012) · Behavior (427) · Behavioral Symptoms (363) · Urogenital Diseases (220) · Female Urogenital Diseases and Pregnancy Complications (219) · Pregnancy Complications (217) · Puerperal Disorders (213) · Pathological Conditions, Signs and Symptoms (107) · Bipolar and Related Disorders (90) · Signs and Symptoms (66) · Schizophrenia Spectrum and Other Psychotic Disorders (62) · Nervous System Diseases (59) · Pathologic Processes (49)
Cognitive Behavioral Therapy (45) · Transcranial Magnetic Stimulation (40) · Therapeutics (39) · Escitalopram (18) · Exercise (17) · Transcranial Direct Current Stimulation (17) · Mindfulness-Based Cognitive Therapy (13) · Fluoxetine (12) · Sertraline (12) · Interpersonal Psychotherapy (11) · Ketamine (10) · Palliative Care (10) · Phototherapy (10) · Standard of Care (10) · Psychotherapy (8)
Massachusetts General Hospital (36) · Centre for Addiction and Mental Health (31) · New York State Psychiatric Institute (18) · Stanford University (18) · University of California, San Francisco (17) · University of Pennsylvania (14) · University of Washington (14) · McMaster University (13) · VA Office of Research and Development (13) · University of Michigan (12) · University of North Carolina, Chapel Hill (11) · Dartmouth-Hitchcock Medical Center (10) · Universitätsklinikum Hamburg-Eppendorf (9) · Charite University, Berlin, Germany (8) · Ludwig-Maximilians - University of Munich (8)
United States (481) · Canada (100) · Germany (54) · Turkey (Türkiye) (37) · France (35) · China (33) · United Kingdom (26) · Denmark (25) · Spain (20) · Israel (17) · Sweden (17) · Taiwan (16) · Hong Kong (14) · Australia (13) · Pakistan (12)
Ryan Van Lieshout, MD, PhD (6) · Arun Ravindran, MD, PhD (4) · Daniel Blumberger, MD (4) · Daniel Blumberger, MD, MSc (3) · Daniel F Gros, PhD MA BS (3) · Darius Tandon, PhD (3) · Dror Ben-Zeev, PhD (3) · Flavio Frohlich, PhD (3) · Leslie Swanson, Ph.D. (3) · Martha G Welch, MD (3) · Maurizio Fava, MD (3) · Rhonda Boyd, PhD (3) · Roberto Lewis-Fernandez, MD (3) · Sona Dimidjian, PhD (3)
PMID 42383885, PMID 27488181, PMID 34286512, PMID 34874888, PMID 38819882, PMID 34817851, PMID 22581378, PMID 25083802, PMID 25374288, PMID 26604001, PMID 26903254, PMID 27227751, PMID 27780336, PMID 28057609, PMID 28231791, PMID 29701939, PMID 30854751, PMID 32090783, PMID 34232578, PMID 38743265, PMID 11939866, PMID 12472325, PMID 15067160, PMID 15183601, PMID 15213794, PMID 15821196, PMID 15876903, PMID 15939840, PMID 16086620, PMID 16139580, PMID 16139581, PMID 16139582, PMID 16174141, PMID 16308576, PMID 16315269, PMID 16343032, PMID 16449615, PMID 16717171, PMID 16844889, PMID 16862248, PMID 17209145, PMID 17335327, PMID 17503104, PMID 17503986, PMID 17547480, PMID 17573044, PMID 17683643, PMID 17922939, PMID 17993363, PMID 18206856
2019 (2), R01MH039188 (2), R01MH042931 (2), R01MH077210 (2), R01MH101547 (2), R21HD101786 (2), R21MD011320 (2), R34AT011221 (2), R34MH083866 (2), R34MH103568 (2), R61MH118405 (2), U19MH095687 (2), 2005 (1), 2014 (1), 2016 (1)