88 completed. 88 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 88 | Completed 88 |
Follow Deglutition Disorders: new trials by email Literature Review of Deglutition Disorders trials Research Report on Deglutition Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Therapeutic Effect of Vonoprazan Versus Dexlansoprazole in Treatment of Gastroesophageal Reflux Disease Dexlansoprazole 60 mg, Vonoprazan 20 mg bid - Vonoprazan, Proton Pump Inhibitor | Phase 4 | Completed | Ayman Magd Eldin Mohammad Sadek | 136 | 2024-10-01 | 2025-02-27 |
| Effect of Bioflor on Gut Microbiota in Proton-Pump Inhibitor Users Saccharomyces Boulardii 250 MG, Proton Pump Inhibitors (PPI) - Dysbiosis, Gastroesophageal Reflux Disease (GERD) | Phase 4 | Completed | Seoul National University Hospital | 80 | 2024-07-18 | 2026-10-01 |
| Botox or Botox With Esophageal Dilation in Patients With Achalasia Botulinum toxin type A, Endoscope balloon dilator, Patient reported outcomes - Achalasia | Phase 4 | Completed | Vanderbilt University Medical Center | 9 | 2019-05-13 | 2026-08-26 |
| Clinical Trial to Evaluate the Efficacy and Safety of EsoDuo Tab. 20/800mg EsoDuo Tab. 20/800mg - Non-erosive Reflux Disease(NERD) | Phase 4 | Completed | Chong Kun Dang Pharmaceutical | 379 | 2019-01-29 | 2019-12-24 |
| Dysphagia Following Anterior Cervical Spine Surgery; Single Dose Steroid vs Saline (DysDexVSSal) Dexamethasone, Saline - Dysphagia | Phase 4 | Completed | West Virginia University | 78 | 2018-09-07 | 2025-02-12 |
| Effect of Obesity on Proton Pump Inhibitors Lansoprazole, Pantoprazole, Midazolam - Pediatric Obesity, NAFLD | Phase 4 | Completed | Children's Mercy Hospital Kansas City | 76 | 2018-07-03 | 2026-06-04 |
| Efficacy and Safety Evaluation of Neobianacid® in GERD and EPS Neobianacid®, Omeprazole 20mg, Neobianacid® placebo - GERD, EPS | Phase 4 | Completed | Aboca Spa Societa' Agricola | 275 | 2017-09-12 | 2022-11-21 |
| Codeine on Pharyngeal and Esophageal Motility Codeine Phosphate, Siripus simplex - Esophageal Motility Disorders | Phase 4 | Completed | Universitaire Ziekenhuizen KU Leuven | 22 | 2017-09-07 | 2018-12-24 |
| Comparison of the Effect of Rabeprazole 50 mg DDR Capsules and 20 mg Enteric-coated Tablets Rabelis DDR 50 mg Capsules, Pariet 20 mg Enteric Coated Tablets - Gastroesophageal Reflux Disease | Phase 4 | Completed | Neutec Ar-Ge San ve Tic A.Ş | 48 | 2017-08-01 | 2018-12-12 |
| Methoclopramide for Gastroesophageal Reflux in Premature Infants Metoclopramide, Placebo - Gastroesophageal Reflux | Phase 4 | Completed | Nathalie Charpak | 490 | 2017-04-26 | 2020-09-02 |
| An Open-Label Trial of Dexlansoprazole 60mg for the Relief of Heartburn During the Fasting Month of Ramadan Dexlansoprazole 60 MG - GERD, Proton Pump Inhibitor | Phase 4 | Completed | American University of Beirut Medical Center | 33 | 2017-02-27 | 2017-09-15 |
| Safety and Efficacy of a Sore Throat Lozenge DORITHRICIN in Patients With Acute Pharyngitis Benzalkonium Chloride-Benzocaine Topical, Placebo Oral Tablet - Pharyngitis | Phase 4 | Completed | Medice Arzneimittel Pütter GmbH & Co KG | 321 | 2017-02-01 | 2017-11-28 |
| Effect of Citalopram on Reflux Episodes in Healthy Volunteers Citalopram HCl, Placebos - Gastro Esophageal Reflux | Phase 4 | Completed | Universitaire Ziekenhuizen KU Leuven | 19 | 2017-02-01 | 2018-11-20 |
| Implementation of PPI Medication PGX Testing Genotype Guided PPI Dosing - Gastroesophageal Reflux | Phase 4 | Completed | Nemours Children's Clinic | 28 | 2016-07-21 | 2018-11-21 |
| The Effect of Dexrabeprazole on Intragastric and Intraesophageal Acidity Dexrabeprazole 10 mg Enteric-Coated Tablets - Gastroesophageal Reflux Disease (GERD) | Phase 4 | Completed | Neutec Ar-Ge San ve Tic A.Ş | 12 | 2016-02-01 | 2017-08-24 |
| The CALIBER Study Randomized Controlled Trial of LINX Versus Double-Dose Proton Pump Inhibitor Therapy for Reflux Disease Omeprazole, LINX Reflux Management System - GERD Gastroesophageal Reflux Disease | Phase 4 | Completed | Torax Medical Incorporated | 152 | 2015-06-01 | 2019-01-07 |
| Dexlansoprazole in Asian Participants With Gastroesophageal Reflux Disease Dexlansoprazole - Gastroesophageal Reflux Disease | Phase 4 | Completed | Takeda | 296 | 2015-03-19 | 2017-10-04 |
| Hypoallergenic Infant Formula Containing Starch and the Probiotic: Effect on Gastric Emptying HA formula + starch + L. reuteri - Regurgitation, Gastric | Phase 4 | Completed | University of Bari | 132 | 2014-10-01 | 2015-04-01 |
| The Effect of Corticotrophin-releasing Hormone (CRH) on Esophageal Motility in Healthy Volunteers CRH - Esophageal Motility Disorders | Phase 4 | Completed | Prof Dr Jan Tack | 14 | 2014-10-01 | 2016-04-13 |
| The Prospective Study on the Effect of Ilaprazole in Non-erosive Reflux Disease Patients; Focused on Histologic Findings and Inflammatory Biomarker Ilaprazole - Gastrointestinal Subepithelial Tumors | Phase 4 | Completed | Yonsei University | 20 | 2014-07-01 | 2019-03-22 |
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Gastroesophageal Reflux (70) · Heartburn (14) · Esophagitis, Peptic (4) · Laryngopharyngeal Reflux (3) · Esophageal Motility Disorders (2) · Laryngeal Diseases (2) · Non-Erosive Reflux Disease (2) · Stroke (2) · Achlorhydria (1) · Airway Obstruction (1) · Barrett Esophagus (1) · Bronchopulmonary Dysplasia (1) · Cerebral Palsy (1) · Cough (1)
Digestive System Diseases (88) · Esophageal Diseases (88) · Gastrointestinal Diseases (88) · Esophageal Motility Disorders (77) · Pathological Conditions, Signs and Symptoms (23) · Signs and Symptoms (18) · Signs and Symptoms, Digestive (15) · Otorhinolaryngologic Diseases (13) · Respiratory Tract Diseases (11) · Pharyngeal Diseases (10) · Gastroesophageal Reflux (6) · Stomach Diseases (6) · Gastroenteritis (5) · Nervous System Diseases (5)
Esomeprazole (31) · Rabeprazole (10) · Lansoprazole (9) · Omeprazole (8) · Pantoprazole (8) · Dexlansoprazole (4) · Domperidone (2) · Endoscopy, Digestive System (2) · Fundoplication (2) · Proton Pump Inhibitors (2) · Restraint, Physical (2) · Sodium Chloride (2) · 1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine (1) · Acetaminophen (1) · Ambulatory Care Facilities (1)
AstraZeneca (23) · Takeda (5) · Neutec Ar-Ge San ve Tic A.Ş (3) · Chong Kun Dang Pharmaceutical (2) · Universitaire Ziekenhuizen KU Leuven (2) · Vanderbilt University Medical Center (2) · Aboca Spa Societa' Agricola (1) · American University of Beirut Medical Center (1) · Ayman Magd Eldin Mohammad Sadek (1) · Brigham and Women's Hospital (1) · Children's Hospital Srebrnjak (1) · Children's Mercy Hospital Kansas City (1) · Chinese University of Hong Kong (1) · Digestive & Liver Disease Specialists (1) · Dr. Reddy's Laboratories Limited (1)
United States (26) · South Korea (6) · Germany (5) · Belgium (4) · Turkey (Türkiye) (4) · France (3) · Italy (3) · Sweden (3) · Taiwan (3) · United Kingdom (3) · Canada (2) · China (2) · Colombia (2) · Denmark (2) · Hong Kong (2)
Paula Fernstrom (6) · Nicholas Shaheen, MD, MPH (2) · Andreas Franke, MD (1) · Anna Guillen, MD (1) · Ayman Sadek, MD (1) · Ayse Baysal, MD (1) · Carol MacArthur, MD (1) · David A Johnson, MD (1)
PMID 25478944, PMID 15519198, PMID 16882832, PMID 17305763, PMID 17331245, PMID 17377079, PMID 18279773, PMID 18493207, PMID 19114878, PMID 19210493, PMID 19236727, PMID 19445547, PMID 19601705, PMID 19925497, PMID 19960205, PMID 20132153, PMID 20456300, PMID 20540767, PMID 20551454, PMID 20578215, PMID 20706150, PMID 21028753, PMID 21083590, PMID 21083673, PMID 21288053, PMID 21317257, PMID 21347742, PMID 21546269, PMID 22429630, PMID 22759841, PMID 22813439, PMID 23432146, PMID 24083350, PMID 24917966, PMID 25304129, PMID 26121347, PMID 26121348, PMID 26422095, PMID 26422096, PMID 28780072, PMID 29024410, PMID 30031018, PMID 30329199, PMID 30625462, PMID 31118571, PMID 31518717, PMID 32095968, PMID 32467089, PMID 33232555, PMID 33705573
2016 (1), K23DK115827 (1)