28 completed, 8 terminated, 8 unknown, 5 no longer available. 13 Not applicable, 11 Phase 3, 11 Phase 4, 10 Phase 2, 3 Phase 1.
Follow Domperidone: new trials by email Literature Review of Domperidone trials Research Report on Domperidone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Digestive Enzymes as Add on Therapy on Patients With Functional Dyspepsia. Digestive enzyme 325mg, PPI 20 mg + Domperidone 10 mg - Dyspepsia, Functioanl Dyspepsia | Phase 4 | Not yet recruiting | Rakibul Mostafa | 120 | 2026-05-15 | 2026-05-11 |
| Efficacy of Domperidone (a Prokinetic Agent) on Time in Range in Digestively Asymptomatic Type I Diabetic Patients With Delayed Gastric Emptying (Gastro-TIR) Domperidone 10mg, Placebo, gastric emptying test - Type 1 Diabetic | Phase 3 | Not yet recruiting | University Hospital, Rouen | 70 | 2026-03-01 | 2026-02-17 |
| Emotions, Dopamine, Brain and Body Domperidon, Placebo - Emotions | Phase 4 | Unknown | German Institute of Human Nutrition | 40 | 2023-08-01 | 2023-12-14 |
| Efficacy of ASIMOMMY® Compared to Domperidone and Placebo in Increasing Breastfeeding: Randomized Single-Blind Controlled Trial in Indonesia ASIMOMMY®, Domperidon, Placebo - Breastfeeding Mothers | Phase 2 | Completed | Gadjah Mada University | 45 | 2022-12-31 | 2023-03-29 |
| Study of Effects of Preoperative Oral Domperidone on Gastric Residual Volume After Clear Fluid Ingestion in Patients Scheduled for Elective Surgeries Domperidone, Folic acid - Gastric Residual Volume | Phase 3 | Completed | Ain Shams University | 40 | 2022-10-10 | 2023-05-15 |
| The Impact of Air Travel on Passenger Cognitive Functions Citicoline, Cytochrome C6, Sodium Chloride Oral Product - Air Travel | Phase 2 / Phase 3 | Unknown | Dinara Zhumanbayeva | 50 | 2021-06-01 | 2021-03-17 |
| The Effect of Antiemetics on Bowel Preparation Before Colonoscopy Domperidone, sulpiride - Bowel Preparation | Phase 4 | Unknown | RenJi Hospital | 200 | 2020-03-01 | 2020-10-12 |
| Effectiveness of Prokinetic Agents in Improving Abdominal Discomfort at Colonoscopy Itopride, Domperidone, Placebo - Abdominal Pain | Not applicable | Unknown | Mahidol University | 525 | 2019-09-16 | 2021-09-02 |
| A New System for GERD Diagnosis and Treatment Stretta, Laparoscopic Nissen fundoplication, Probiotic Agent - GERD | Unknown | Capital Medical University | 200 | 2019-02-01 | 2019-02-05 | |
| Preliminarily Evaluate the Efficacy of Domperidone in Adult Chinese Participants With Functional Dyspepsia Domperidone, Placebo - Dyspepsia | Phase 4 | Completed | Xian-Janssen Pharmaceutical Ltd. | 160 | 2018-08-27 | 2025-04-27 |
| Cardiac Safety of Lansoprazole and Domperidon Combination Lansoprazole/Domperidone, Lansoprazole - GERD, Cardiac Event | Phase 4 | Withdrawn | Neutec Ar-Ge San ve Tic A.Ş | 2018-03-01 | 2023-01-05 | |
| EFFECT OF LOW LEVEL LASER THERAPY VERSUS ELECTROACUPUNCTURE ON POSTNATAL SCANTY MILK SECRETION domperidone, He-Ne laser (Bravo TrezaSerie) device, faradic current - Insufficient Lactation | Phase 4 | Completed | Cairo University | 60 | 2018-01-02 | 2019-01-16 |
| Effect of Domperidone on Completion Rate of Vedio Capsule Endoscopy Domperidone, water - Capsule Endoscopy, Pediatric Disorder | Not applicable | Completed | Children's Hospital of Fudan University | 200 | 2017-11-01 | 2018-12-17 |
| Domperidone and Risk of Serious Cardiac Events in Postpartum Women Domperidone, No domperidone - Ventricular Tachyarrhythmia, Sudden Cardiac Death | Completed | Canadian Network for Observational Drug Effect Studies, CNODES | 184929 | 2017-09-01 | 2024-09-19 | |
| Study to Evaluate the Effects of Domperidone on Cardiac Repolarization in Chinese Healthy Participants Domperidone, Placebo, Moxifloxacin - Healthy | Phase 1 | Completed | Janssen Research & Development, LLC | 44 | 2016-05-01 | 2025-02-03 |
| A Study to Evaluate the Safety and Efficacy of Domperidone in Pediatric Participants With Nausea and Vomiting Due to Acute Gastroenteritis Oral Rehydration Therapy, Domperidone, Placebo - Gastroenteritis | Phase 3 | Terminated | Janssen-Cilag International NV | 10 | 2015-12-07 | 2019-03-20 |
| Pilot Trial of Domperidone in Relapsing-Remitting Multiple Sclerosis (RRMS) Domperidone - Multiple Sclerosis, Relapsing-Remitting | Phase 2 | Completed | University of Calgary | 17 | 2015-08-01 | 2019-10-08 |
| Domperidone in Secondary Progressive Multiple Sclerosis (SPMS) Domperidone - Multiple Sclerosis, Secondary Progressive | Phase 2 | Completed | University of Calgary | 64 | 2015-02-01 | 2020-02-24 |
| Effects and Mechanism of Mosapride Citrate on Diabetic Gastroparesis Mosapride, domperidone - Diabetic Gastroparesis | Phase 4 | Unknown | Liangzhou Wei | 60 | 2014-10-01 | 2014-10-15 |
| The Efficacy of Lansoprazole and Domperidone Combination on Intragastric and Intraesophageal Acidity Lansoprazole/Domperidone - Gastroesophageal Reflux Disease | Phase 4 | Completed | Neutec Ar-Ge San ve Tic A.Ş | 12 | 2014-01-01 | 2016-11-08 |
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Gastroparesis (13) · Gastroesophageal Reflux (12) · Dyspepsia (5) · Parkinson Disease (5) · Vomiting (4) · Breast Feeding (3) · Death, Sudden, Cardiac (3) · Digestive System Diseases (3) · Esophagitis (3) · Nausea (3) · Gastroenteritis (2) · Premature Birth (2) · Tachycardia, Ventricular (2) · Abdominal Pain (1) · Breast Neoplasms (1)
Janssen Research & Development, LLC (3) · Canadian Network for Observational Drug Effect Studies, CNODES (2) · Neutec Ar-Ge San ve Tic A.Ş (2) · University of Calgary (2) · Yale University (2) · Ain Shams University (1) · Allegiance Health (1) · Arnold, George, M.D. (1) · Cairo University (1) · Capital Medical University (1) · Carle Physician Group (1) · Children's Hospital of Fudan University (1) · David J. Lederer, M.D. (1) · Dinara Zhumanbayeva (1) · Eastern Regional Medical Center (1)
United States (14) · Canada (9) · China (5) · Belgium (3) · Brazil (2) · Egypt (2) · Spain (2) · Thailand (2) · Turkey (Türkiye) (2) · United Kingdom (2) · Australia (1) · Austria (1) · Bangladesh (1) · France (1) · Germany (1)
Ahmed Maged (1) · Amir Shafat (1) · Amit Garg (1) · Andrew Batey, M.D. (1) · Anish A Sheth, MD (1) · Anna Keck, PhD (1) · Chairat Supsamutchai, MD (1) · Cheol Min Shin, M.D., Ph.D. (1) · Chingching Foocharoen, MD (1) · Christel Renoux, MD, PhD (1) · Chuan Zhang, MD (1) · David J Lederer, M.D. (1) · Elizabeth V Asztalos, MD (1) · Eric Vuurman, Dr. (1)
PMID 10332535, PMID 12118964, PMID 16553582, PMID 16997628, PMID 17488253, PMID 18577886, PMID 19866393, PMID 20008425, PMID 22124998, PMID 22391645, PMID 22935052, PMID 24440931, PMID 26994459, PMID 27062307, PMID 27179107, PMID 28107101, PMID 29705555, PMID 30410781, PMID 30543461, PMID 31171928, PMID 31181017, PMID 31327162, PMID 32421208, PMID 33708520, PMID 33990364, PMID 34000076, PMID 34038379, PMID 38461731, PMID 9177513
2015 (1)