49 completed, 13 unknown, 8 not yet recruiting, 5 recruiting. 19 Not applicable, 19 Phase 3, 9 Phase 4, 7 Phase 1, 7 Phase 2.
Follow Esophagitis, Peptic: new trials by email Literature Review of Esophagitis, Peptic trials Research Report on Esophagitis, Peptic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pilot Study of Salivary Bile Acids and Pepsin as Predictive Biomarkers of Reflux Disease After Sleeve Gastrectomy Reflux Disease, Gastro-Esophageal, Sleeve Gastrectomy | Not yet recruiting | Hospital de Mataró | 60 | 2026-12-01 | 2026-05-26 | |
| PPI Dosing Per CYP2C19 Genotype CYP2C19 based dosing Proton Pump Inhibitors, Conventional proton pump inhibitor dose - Gastroesophageal Reflux Disease With Esophagitis | Phase 4 | Not yet recruiting | University of Florida | 200 | 2026-10-01 | 2026-09-28 |
| Preoperative Predictors of Symptom Improvement After Laparoscopic Fundoplication Laparoscopic Nissen fundoplication, Laparoscopic Toupet fundoplication - Gastroesophageal Reflux Disease, Hiatal Hernia | Recruiting | Minia University | 470 | 2026-09-20 | 2026-09-22 | |
| Sino-Russian Comparison of Outcomes After Proximal Gastrectomy With Double-Tract Reconstruction Proximal gastrectomy with double-tract reconstruction - Gastric Adenocarcinoma, Adenocarcinoma of the Esophagogastric Junction | Not yet recruiting | The First Affiliated Hospital with Nanjing Medical University | 250 | 2026-08-15 | 2026-09-02 | |
| Sling-Fiber Preservation POEM vs. Conventional POEM for Reducing Post-POEM GERD Conventional POEM, Sling Fiber-Preserving POEM - Achalasia, Esophageal, GERD (Gastroesophageal Reflux Disease) | Not applicable | Not yet recruiting | University of California, Irvine | 120 | 2025-12-01 | 2025-10-22 |
| A Prospective Cohort Study on Endoscopic Features of Upper Gastrointestinal Tract at High Altitude (Zaduo County) Sedated gastroscopy - Reflux Esophagitis | Recruiting | Jilin University | 60 | 2025-12-01 | 2026-08-10 | |
| A Clinical Trial of Anaprazole for Treating Reflux Esophagitis. Anaprazole + Rabeprazole placebo, Rabeprazole + Anaprazole placebo - Reflux Esophagitis (RE) | Phase 3 | Recruiting | Xuanzhu Biopharmaceutical Co., Ltd. | 500 | 2025-07-30 | 2025-09-29 |
| Preliminary Efficacy Analysis of "C" Single Flap Plasty Reconstruction After Laparoscopic Proximal Gastrectomy "C" Single Flap Plasty Reconstruction, Normal Reconstruction - Gastric Cancer, Reflux Esophagitis | Not applicable | Not yet recruiting | Daorong Wang | 50 | 2025-01-01 | 2024-12-19 |
| A Phase III Clinical Trial for Efficacy and Safety Evaluation of JP-1366 Tablets on Reflux Esophagitis JP-1366 simulation tablets, Esomeprazole Magnesium (Nexium) simulation tablets - Reflux Esophagitis (RE) | Phase 3 | Recruiting | Livzon Pharmaceutical Group Inc. | 356 | 2024-12-05 | 2025-02-27 |
| Preliminary Efficacy Analysis of 'λ+α' Double-Tract Reconstruction After Laparoscopic Proximal Gastrectomy proximal gastrectomy combined with 'λ+α' double-tract anastomosis - Gastric Cancer, Reflux Esophagitis | Not applicable | Unknown | Northern Jiangsu People's Hospital | 60 | 2024-08-01 | 2024-08-15 |
| FundoRing Roux-en-Y Gastric Bypass Versus FundoRing One Anastomosis Gastric Bypass Laparoscopic FundoRing gastric bypass - Obesity, Roux-en-y Anastomosis Site | Not applicable | Completed | The Society of Bariatric and Metabolic Surgeons of Kazakhstan | 200 | 2024-07-04 | 2026-03-20 |
| Feasibility and Safety of Robotic Assisted Proximal Gastrectomy With Double-flap Technique for Proximal Early Gastric Cancer Robotic assisted proximal gastrectomy with double-flap technique - Stomach Neoplasms | Not applicable | Recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 42 | 2024-06-10 | 2025-05-25 |
| Protocol for Comparing the Efficacy of Three Reconstruction Methods of the Digestive Tract After Proximal Gastrectomy Kamikawa, STJI, SOFY - Proximal Gastric Adenocarcinoma, Gastrectomy | Not applicable | Not yet recruiting | Changzhi People's Hospital Affiliated to Changzhi Medical College | 180 | 2023-10-01 | 2023-10-05 |
| Jinghua Weikang Capsule in the Treatment of Reflux Esophagitis jinghua weikang capsule - Reflux Esophagitis | Phase 4 | Unknown | The First Affiliated Hospital of Dalian Medical University | 260 | 2023-10-01 | 2023-09-28 |
| Treatment of Reflux With Sleeve Gastrectomy Laparoscopic Sleeve Gastrectomy - Reflux Disease, Gastro-Esophageal, Hiatal Hernia | Not applicable | Unknown | Yusuf Emre ALTUNDAL | 80 | 2023-09-25 | 2023-12-27 |
| Laparoscopic Proximal Gastrectomy With Double-flap Technique Versus Laparoscopic Total Gastrectomy With Roux-en-Y Reconstruction for Proximal Early Gastric Cancer Laparoscopic Proximal Gastrectomy With Double-flap Technique, Laparoscopic Total Gastrectomy With Roux-en-Y Reconstruction - Stomach Neoplasms | Not applicable | Not yet recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 216 | 2023-06-10 | 2023-06-06 |
| Role of ARMA in Selective Subset of Refractory GERD Patients. ARMA, UGI Endoscopy - GERD, Reflux | Not applicable | Completed | Asian Institute of Gastroenterology, India | 50 | 2023-03-30 | 2025-04-04 |
| A Study of Anaprazole Sodium Enteric-coated Tablets in the Treatment of Reflux Esophagitis Anaprazole sodium 40 mg, Anaprazole sodium 60 mg, Rabeprazole sodium 20 mg - Reflux Esophagitis, Gastroesophageal Reflux | Phase 2 | Unknown | Xuanzhu Biopharmaceutical Co., Ltd. | 156 | 2022-12-01 | 2022-11-03 |
| Clinical Trial of Reconstruction After Proximal Gastrectomy left-opening single-flap technique, double-flap group technique - Esophagitis, Reflux | Not applicable | Not yet recruiting | Oncogastroenterology Committee of Chinese | 250 | 2022-08-01 | 2022-07-05 |
| Mass Balance Study of [14C]X842 in Healthy Adult Male Subjects [14C]X842 - Gastroesophageal Reflux Disease | Phase 1 | Completed | Jiangsu Sinorda Biomedicine Co., Ltd | 6 | 2022-06-15 | 2025-08-06 |
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Gastroesophageal Reflux (27) · Barrett Esophagus (6) · Duodenal Ulcer (6) · Stomach Neoplasms (6) · Stomach Ulcer (6) · Heartburn (4) · Esophagitis (3) · Hernia, Hiatal (3) · Non-Erosive Reflux Disease (3) · Zollinger-Ellison Syndrome (3) · Esophageal Diseases (2) · Peptic Ulcer (2) · Acute Coronary Syndrome (1) · Adenocarcinoma (1)
Digestive System Diseases (81) · Duodenal Diseases (81) · Gastroenteritis (81) · Intestinal Diseases (81) · Stomach Diseases (81) · Gastrointestinal Diseases (80) · Esophageal Diseases (79) · Peptic Ulcer (79) · Esophagitis (78) · Deglutition Disorders (28) · Esophageal Motility Disorders (28) · Neoplasms (15) · Pathological Conditions, Signs and Symptoms (13) · Digestive System Neoplasms (10) · Gastrointestinal Neoplasms (10)
Esomeprazole (9) · Lansoprazole (9) · Rabeprazole (8) · Dexlansoprazole (6) · Omeprazole (5) · YF 476 (4) · 1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine (3) · Clopidogrel (2) · Aspirin (1) · DA-5204 (1) · Dosage Forms (1) · Endoscopy (1) · Famotidine (1) · Fundoplication (1) · Nutrition Assessment (1)
AstraZeneca (11) · Takeda (10) · Trio Medicines Ltd. (4) · Jiangsu Sinorda Biomedicine Co., Ltd (3) · National Taiwan University Hospital (3) · Eisai Co., Ltd. (2) · Seoul National University Bundang Hospital (2) · Seoul National University Hospital (2) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (2) · Xuanzhu Biopharmaceutical Co., Ltd. (2) · Affiliated Hospital to Academy of Military Medical Sciences (1) · Asian Institute of Gastroenterology, India (1) · Changzhi People's Hospital Affiliated to Changzhi Medical College (1) · Chong Kun Dang Pharmaceutical (1) · Chuncheon Sacred Heart Hospital (1)
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Bor-Ru Lin, M.D. (2) · Malcolm Boyce (2) · Malcolm J Boyce, FRCP FFPM (2) · Maotsugu Oyama, MD, PhD (2) · Pingsheng Hu, Ph.D (2) · Shigeru Yoshida, MD (2) · Alan Thomson, MD, Prof. (1) · Chao Zhang, MD (1) · Christoph Beglinger, Prof. (1) · Cord Langner, MD (1) · Digvijay Chavan (1) · Dong Ho Lee, MD, PhD (1)
PMID 19735233, PMID 20195905, PMID 21129076, PMID 19183157, PMID 19681809, PMID 22607579, PMID 23451835, PMID 24118079, PMID 17305763, PMID 19210298, PMID 20379093, PMID 20925534, PMID 21356058, PMID 22464259, PMID 23333143, PMID 27012778, PMID 27187303, PMID 27694141, PMID 28502925, PMID 32010745, PMID 33512805, PMID 34628734, PMID 34754155, PMID 36109362, PMID 36465382, PMID 38251791, PMID 38964794, PMID 39836012, PMID 40789587, PMID 41982134, PMID 42168696
2018 (1), R01DK063621 (1), R03DC005917 (1)