40 completed, 14 recruiting, 13 unknown, 8 not yet recruiting. 48 Not applicable, 5 Phase 4, 3 Phase 3, 1 Phase 2.
Follow this condition Literature Review of Hernia, Hiatal trials Research Report on Hernia, Hiatal
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Image-Guided Herniorrhaphy Study Image-Guided Herniorrhaphy - Hernia, Hernia Abdominal Wall | Not applicable | Not yet recruiting | University of California, Davis | 30 | 2026-12-01 | 2026-08-31 |
| Antireflux Surgery Without Preoperative Esophageal Manometry Preoperative workup without high-resolution esophageal manometry, Standard preoperative workup with high-resolution esophageal manometry - GERD, Hiatal Hernia | Not applicable | Not yet recruiting | McMaster University | 96 | 2026-10-01 | 2026-08-10 |
| Preoperative Predictors of Symptom Improvement After Laparoscopic Fundoplication Laparoscopic Nissen fundoplication, Laparoscopic Toupet fundoplication - Gastroesophageal Reflux Disease, Hiatal Hernia | Recruiting | Minia University | 470 | 2026-09-20 | 2026-09-22 | |
| Comparison of Laparoscopic Nissen Fundoplication and Hill-Snow Repair for Hiatus Hernia With Endoscopic Evaluation Laparoscopic Hill-Snow repair, Laparoscopic Nissen Fundoplication - Hiatal Hernia With Gastroesophageal Reflux Disease | Not applicable | Not yet recruiting | Minia University | 40 | 2026-03-01 | 2026-02-04 |
| Phrenoesophageal Ligament Reconstruction With Mesh Phrenoesophageal Ligament Reconstruction with Mesh: A New Approach to Hiatal Hernia Repair (Alinasser's Technique), Classic approach - Hiatus Hernia, Gastreoesophageal Reflux Disease | Not applicable | Not yet recruiting | Clinical Trial Aseer | 60 | 2025-12-20 | 2025-11-26 |
| Evaluating Clinical Hiatal Hernia Outcomes Using OviTex® OviTex Reinforced Tissue Matrix - Hiatal Hernia | Not applicable | Recruiting | Tela Bio Inc | 173 | 2025-07-25 | 2026-08-18 |
| Laparoscopic Hiatal Hernia Repair With Mesh Cruroplasty Hiatal Hernia (HH) repair using mesh cruroplasty during a Laparoscopic Sleeve Gastrectomy (LSG) - Hiatal Hernia, Sleeve Gastrectomy | Not applicable | Completed | Zagazig University | 20 | 2025-06-26 | 2026-03-24 |
| Comparative 3-year Study of Nissen-sleeve vs. Sleeve Plus Cruroplasty in Obese Patients With Hiatal Hernia Ph-measurement, Questionnaires, gastroduodenal transit - Obesity, Hiatal Hernia | Not applicable | Not yet recruiting | Elsan | 150 | 2025-03-02 | 2025-02-19 |
| Recto-intercostal Facial Plane Block in Laparoscopic Hiatus Hernia Repair Rectointercostal facial plane block using bupivacaine 0.25%, No Intervention as a control - Rectointercostal, Laparoscopic | Not applicable | Completed | Tanta University | 44 | 2025-02-17 | 2025-08-28 |
| Nissen Versus Dor Hiatal Hernia Repair Nissen fundoplication, Dor fundoplication - Hiatal Hernia, Paraesophageal Hernia | Not applicable | Recruiting | Kuopio University Hospital | 150 | 2025-02-07 | 2025-02-19 |
| Low Pressure Pneumoperitoneum Using AirSeal® for Reduction in Postoperative Shoulder Pain Following Robot Assisted Hiatal Hernia Repair Low pressure pneumoperitoneum (8-10mmHg) with AirSeal device, Standard pressure pneumoperitoneum (13- 15 mmHg) with AirSeal device - Hernia, Hiatal, Pneumoperitoneum | Not applicable | Not yet recruiting | Riverside University Health System Medical Center | 120 | 2025-01-01 | 2024-12-17 |
| Laparoscopic Toupet's Fundoplication: Is it Proper Solution of Radiological Negative, Endoscopically Positive Hiatal Hernia Patients Laparoscopic toupet fundoplication - Laparoscopic Toupet Fundoplication, Radiological Negative | Not applicable | Completed | Minia University | 100 | 2024-10-01 | 2026-05-20 |
| Impact of Biosynthetic Mesh on Paraesophageal Hernia Repair Biosynthetic Mesh, Hiatal Hernia Repair - Hiatal Hernia | Not applicable | Recruiting | Weill Medical College of Cornell University | 200 | 2024-06-10 | 2026-08-19 |
| Gastropexy as a Treatment Option for Paraesophageal Hernia no intervention, but surgical practice as usual is continued. Its a pragmatic study - Paraesophageal Hernia | Not yet recruiting | University Hospital of North Norway | 220 | 2024-06-01 | 2023-10-23 | |
| Posterior Rectus Sheath Hiatal Augmentation in Paraesophageal Hernia Repair POSTERIOR RECTUS SHEATH HIATAL AUGMENTATION (PORSHA) - Paraesophageal Hernia | Recruiting | University of Chicago | 100 | 2024-05-15 | 2026-02-02 | |
| Safety and Feasibility of Liver Retraction With the Levita Magnetic Surgical System: Extended Magnetic Grasper Device Extended Magnetic Grasper Device - Bariatric Surgery Candidate, Hiatal Hernia | Not applicable | Completed | Levita Magnetics | 30 | 2024-05-13 | 2025-05-29 |
| A Prospective Randomised Multi - Center Trial on the Repair of Large Hiatal Hernias: Absorbable Mesh vs. Pledgeted Sutures vs. Sutures Only Laparoscopic or robot-assisted hiatal closure (sutures only vs. absorbable mesh vs. pledgeted sutures) and fundoplication according to Toupet - Hiatal Hernia | Not applicable | Not yet recruiting | Paracelsus Medical University | 165 | 2024-05-01 | 2024-04-02 |
| TLSA Versus TBSA Surgical Approach for Hiatal Hernia With Gastroesophageal Reflux Disease Laparoscopic total left-sided surgical approach, Laparoscopic traditional bilateral approach - Hernia, Hiatal, GERD (Gastroesophageal Reflux Disease) | Not applicable | Recruiting | Beijing Friendship Hospital | 143 | 2024-04-04 | 2025-11-26 |
| Reducing Postoperative Opioids in Patients Undergoing Laparoscopic Hiatal Hernia Opioid Sparing Anesthesia Protocol (OSA), Opioid Based Anesthesia Protocol (OBA) - Hiatal Hernia | Not applicable | Completed | Endeavor Health | 50 | 2024-03-03 | 2026-08-13 |
| Ovitex in Paraesophageal and Large Hiatal Hernia Repair Ovitex LPR - Paraesophageal Hernia, Large Hiatal Hernia | Not applicable | Recruiting | Foregut Research Foundation | 100 | 2024-02-19 | 2026-02-09 |
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Gastroesophageal Reflux (36) · Hernia (7) · Recurrence (5) · Esophagitis (4) · Barrett Esophagus (3) · Esophagitis, Peptic (3) · Deglutition Disorders (2) · Esophageal Achalasia (2) · Heartburn (2) · Hernia, Diaphragmatic (2) · Hernia, Ventral (2) · Shoulder Pain (2) · Body Weight (1) · Cholecystitis (1)
Pathological Conditions, Anatomical (83) · Pathological Conditions, Signs and Symptoms (83) · Internal Hernia (82) · Hernia, Diaphragmatic (81) · Hernia (76) · Digestive System Diseases (38) · Esophageal Motility Disorders (36) · Gastrointestinal Diseases (36) · Esophageal Diseases (35) · Deglutition Disorders (34) · Pathologic Processes (9) · Gastroenteritis (8) · Signs and Symptoms (7) · Disease Attributes (5) · Neoplasms (5)
Fundoplication (6) · Blood Specimen Collection (2) · Gastropexy (2) · Laparoscopy (2) · Biopsy (1) · Bronchoscopy (1) · Bupivacaine (1) · Gastroscopy (1) · Herniorrhaphy (1) · Hydrogen-Ion Concentration (1) · Infusions, Parenteral (1) · Lidocaine (1) · Melanocyte-Stimulating Hormones (1) · Surgical Procedures, Operative (1) · Surveys and Questionnaires (1)
University of Bologna (4) · EndoGastric Solutions (3) · Minia University (3) · Beijing Friendship Hospital (2) · Foregut Research Foundation (2) · Karolinska Institutet (2) · Karolinska University Hospital (2) · M.S.T. Medical Surgery Technology LTD. (2) · Mayo Clinic (2) · National Taiwan University Hospital (2) · Odessa National Medical University (2) · University of Nebraska (2) · University of Washington (2) · Wake Forest University Health Sciences (2) · Zagazig University (2)
United States (37) · Egypt (5) · Sweden (5) · Canada (3) · Italy (3) · China (2) · Finland (2) · France (2) · Netherlands (2) · Switzerland (2) · Taiwan (2) · Ukraine (2) · Belgium (1) · Bulgaria (1) · Chile (1)
Anders Thorell, Professor (3) · Brant K Oelschlager, MD (2) · Dmitry Oleynikov, MD (2) · Paul D Colavita, MD (2) · Sandro Mattioli, MD (2) · Volodymyr V. Grubnik, Prof., MD (2) · Abeer Fatima, MSPT-CPPT (1) · Alexis Luna Aufroy, PhD (1) · Andrew JE Seely, MD, PhD (1) · Bor-Ru Lin, M.D. (1) · Brant K. Oelschlager, M.D. (1) · Brent D Matthews, MD (1) · Christy M Dunst, MD (1) · Corey Deeken, PhD (1)
PMID 10801022, PMID 11997814, PMID 19960205, PMID 22146488, PMID 23026445, PMID 23186837, PMID 24113771, PMID 24405544, PMID 25448925, PMID 26227494, PMID 26377635, PMID 26463242, PMID 27005292, PMID 28684261, PMID 28684262, PMID 31086250, PMID 31635110, PMID 32936951, PMID 33567462, PMID 34090551, PMID 35171266, PMID 35511051, PMID 35907909, PMID 37819652, PMID 38026477, PMID 39668544, PMID 39714889, PMID 40603619, PMID 41349840, PMID 41840686, PMID 41848187
2019 (1)