49 completed, 7 terminated, 7 unknown, 5 withdrawn. 71 Phase 2, 19 Phase 1, 12 Phase 3.
Follow Congestive Heart Failure: new trials by email Literature Review of Congestive Heart Failure trials Research Report on Congestive Heart Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Peritoneal Ultrafiltration in Cardio Renal Syndrome. PolyCore (Polydextrin, L-Carnitine, D-xylitol) - Congestive Heart Failure | Phase 1 / Phase 2 | Recruiting | Iperboreal Pharma Srl | 84 | 2025-04-16 | 2025-05-16 |
| Phosphatase Inhibition by Intracoronary Gene Therapy in Subjects With Non-Ischemic NYHA Class III Heart Failure AB-1002 - Congestive Heart Failure | Phase 2 | Active not recruiting | AskBio Inc | 150 | 2023-10-20 | 2025-12-03 |
| Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction SRD-001, Placebo - Congestive Heart Failure, Heart Failure, Systolic | Phase 1 / Phase 2 | Recruiting | Sardocor Corp. | 57 | 2021-09-23 | 2024-03-26 |
| Acupuncture for the Treatment of Medication-Dependent Hypotension in Heart Failure True Acupuncture, Sham Acupuncture - Congestive Heart Failure, Hypotension | Phase 1 / Phase 2 | Unknown | Scripps Health | 40 | 2021-04-20 | 2021-07-07 |
| An Investigational Study of Continuous 8-Hour Intravenous Administrations of BMS-986231 in Participants With Heart Failure and Reduced Heart Function Given a Standard Dose of Loop Diuretic BMS-986231, Furosemide, Placebo - Cardiac Failure, Myocardial Failure | Phase 2 | Completed | Bristol-Myers Squibb | 23 | 2019-01-17 | 2021-02-26 |
| Accessing Mobility Using Wearable Sensors Exercise - COPD, Pulmonary Disease | Phase 1 / Phase 2 | Withdrawn | Baylor College of Medicine | 2018-05-21 | 2025-08-27 | |
| Regression of Fibrosis & Reversal of Diastolic Dysfunction in HFpEF Patients Treated With Allogeneic CDCs Allogeneic Derived Cells, Placebo/Control Arm - Congestive Heart Failure, Heart Failure, Diastolic | Phase 2 | Completed | Cedars-Sinai Medical Center | 27 | 2017-07-12 | 2024-07-25 |
| Sub-Q Versus IV Furosemide in Acute Heart Failure Furosemide Injection Solution (SCP-101), Furosemide Injection Solution, USP - Congestive Heart Failure | Phase 2 / Phase 3 | Completed | Johns Hopkins University | 40 | 2016-02-01 | 2017-12-18 |
| The Use of Intranasal Fentanyl for the Treatment of Incident Dyspnea in Congestive Heart Failure: A Prospective Trial fentanyl - Dyspnea, Congestive Heart Failure | Phase 2 | Completed | St. Boniface Hospital | 8 | 2015-10-01 | 2017-09-28 |
| Study To Evaluate D-Ribose For The Treatment of Congestive Heart Failure D-ribose, Placebo - Congestive Heart Failure | Phase 2 | Withdrawn | RiboCor, Inc. | 2013-07-01 | 2016-07-14 | |
| Study of the Acute Effects of Triheptanoin in Heart Failure Triheptanoin oil - Congestive Heart Failure, Non-ischemic Cardiomyopathy | Phase 1 / Phase 2 | Withdrawn | University of Texas Southwestern Medical Center | 2013-02-01 | 2018-12-14 | |
| Vitamin D3 Supplementation for Heart Failure Patients Placebo Comparator: Sugar Pill, Vitamin D3 (cholecalciferol) - Heart Failure, Vitamin D Deficiency | Phase 2 | Completed | Heidi Moretti, MS, RD | 40 | 2012-08-01 | 2017-04-26 |
| Autonomic Neural Regulation Therapy to Enhance Myocardial Function in Heart Failure (ANTHEM-HF) Study Vagus Nerve Stimulation (VNS) - Congestive Heart Failure | Phase 1 / Phase 2 | Completed | Cyberonics, Inc. | 60 | 2012-07-01 | 2015-02-19 |
| Tadalafil and Nesiritide as Therapy in Pre-clinical Heart Failure Nesiritide, Tadalafil, Placebo - Congestive Heart Failure | Phase 1 / Phase 2 | Completed | Mayo Clinic | 43 | 2012-02-01 | 2018-03-22 |
| Vasodilator Therapy for Heart Failure and Preserved Ejection Fraction Isosorbide Dinitrate, Isosorbide Dinitrate + Hydralazine, Placebo - Heart Failure, Congestive Heart Failure | Phase 2 | Completed | Corporal Michael J. Crescenz VA Medical Center | 44 | 2012-01-01 | 2022-06-21 |
| Liraglutide and Heart Failure in Type 2 Diabetes liraglutide, glimepiride, Metformin - Congestive Heart Failure, Type 2 Diabetes Mellitus | Phase 2 | Completed | Thomas Nystrom | 62 | 2012-01-01 | 2016-09-01 |
| Comparative Study of Cardiopulmonary Exercise Test Land Versus Water Aerobic and anaerobic capacity use aquatic exercises - Congestive Heart Failure | Phase 2 / Phase 3 | Unknown | University of Sao Paulo General Hospital | 90 | 2011-04-01 | 2011-04-28 |
| Feasibility Study of BMAC Enhanced CABG BMAC, CABG only - Congestive Heart Failure | Phase 1 / Phase 2 | Terminated | Harvest Technologies | 5 | 2011-02-01 | 2016-01-18 |
| Blood Pressure Reduction in Heart Failure Hydralazine/amlodipine, Placebo - Heart Failure, Cardiac Failure | Phase 2 / Phase 3 | Completed | University of Sao Paulo | 21 | 2011-01-01 | 2014-06-10 |
| Bosentan for Severe Mitral Valve Dysfunction BOSENTAN - SECONDARY PULMONARY HYPERTENSION, MITRAL STENOSIS | Phase 1 / Phase 2 | Unknown | General Hospital of Chalkida | 10 | 2010-12-01 | 2011-01-28 |
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Heart Failure (71) · Diabetes Mellitus (6) · Renal Insufficiency (5) · Myocardial Infarction (4) · Cardiomyopathies (3) · Myocardial Ischemia (3) · Pulmonary Disease, Chronic Obstructive (3) · Anemia (2) · Cardiovascular Diseases (2) · Heart Diseases (2) · Hyperglycemia (2) · Hypertension (2) · Adenoviridae Infections (1) · Angina Pectoris (1) · Angina, Unstable (1)
Cardiovascular Diseases (69) · Heart Diseases (69) · Pathological Conditions, Signs and Symptoms (11) · Nutritional and Metabolic Diseases (9) · Pathologic Processes (9) · Vascular Diseases (9) · Glucose Metabolism Disorders (8) · Metabolic Diseases (8) · Endocrine System Diseases (7) · Female Urogenital Diseases (6) · Female Urogenital Diseases and Pregnancy Complications (6) · Kidney Diseases (6) · Male Urogenital Diseases (6) · Urogenital Diseases (6) · Urologic Diseases (6)
Natriuretic Peptide, Brain (6) · Darbepoetin alfa (2) · Furosemide (2) · Hydralazine (2) · Saline Solution (2) · Sodium Chloride (2) · Tolvaptan (2) · 5-(formyl-(3-(formyl-(3,5-bis (2,3-dihydroxypropylcarbamoyl)-2,4,6-triiodophenyl) amino)-2-hydroxypropyl)amino)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide (1) · Acupuncture Therapy (1) · Albuterol (1) · Allopurinol (1) · Amlodipine (1) · BAY 58-2667 (1) · Bosentan (1) · Cardiac Resynchronization Therapy (1)
Boston Scientific Corporation (3) · Amgen (2) · Harvest Technologies (2) · Horng Chen (2) · Johns Hopkins University (2) · Kathleen Dungan (2) · Otsuka Pharmaceutical Development & Commercialization, Inc. (2) · Scios, Inc. (2) · US Department of Veterans Affairs (2) · Advanz Pharma (1) · Allina Health System (1) · AskBio Inc (1) · AstraZeneca (1) · Barnes-Jewish Hospital (1) · Bayer (1)
United States (47) · Canada (7) · Germany (6) · United Kingdom (5) · Italy (3) · Poland (3) · Belgium (2) · Brazil (2) · Denmark (2) · Hungary (2) · India (2) · Spain (2) · Sweden (2) · Australia (1) · Austria (1)
Amit Patel, MD (2) · Horng H. Chen, M.D. (2) · Kathleen M Dungan, MD (2) · Andreas M Zeiher, MD (1) · Anitha Vijayan, M.D. (1) · Anju Nohria, MD (1) · Aslan T Turer, MD, MHS (1) · Bijan Najafi, PhD (1) · Boris Nasseri, MD (1) · Bradley D Berry, MD (1)
PMID 15152059, PMID 15319045, PMID 16796497, PMID 17543634, PMID 18549913, PMID 19204305, PMID 19567409, PMID 19919976, PMID 20008582, PMID 20090057, PMID 20154234, PMID 21411144, PMID 22156953, PMID 22361399, PMID 22510424, PMID 22651239, PMID 22728580, PMID 22778174, PMID 22893340, PMID 22936827, PMID 22980293, PMID 23122795, PMID 23487543, PMID 23592107, PMID 23922063, PMID 24497345, PMID 24626998, PMID 25187002, PMID 25319879, PMID 25926562, PMID 26601770, PMID 27221316, PMID 27437887, PMID 28219917, PMID 29084522, PMID 29226816, PMID 29236912, PMID 29548934, PMID 30764699, PMID 31168885, PMID 31909303, PMID 33590355, PMID 34405565, PMID 34920733, PMID 35360224, PMID 35490339, PMID 37349083
P01HL076611 (3), UL1RR024150 (3), R01HL084155 (2), 2004 (1), 2005 (1), 2018 (1), K23DK080891 (1), P01HL066941 (1), R01HL036634 (1), R01HL061912 (1), R21AG043802 (1), R21DK081877 (1)