29 completed, 8 unknown, 6 terminated, 2 recruiting. 47 Phase 1, 19 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 47 | Completed 29, Unknown 8, Terminated 6, Recruiting 2, Withdrawn 2 |
| Phase 2 | 19 | Completed 10, Unknown 3, Recruiting 2, Terminated 2, Withdrawn 2 |
Follow Congestive Heart Failure: new trials by email Literature Review of Congestive Heart Failure trials Research Report on Congestive Heart Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Peritoneal Ultrafiltration in Cardio Renal Syndrome. PolyCore (Polydextrin, L-Carnitine, D-xylitol) - Congestive Heart Failure | Phase 1 / Phase 2 | Recruiting | Iperboreal Pharma Srl | 84 | 2025-04-16 | 2025-05-16 |
| Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for Heart Disease AlloRx - Congestive Heart Failure, Angina | Phase 1 | Terminated | The Foundation for Orthopaedics and Regenerative Medicine | 3 | 2022-02-01 | 2026-10-20 |
| Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction SRD-001, Placebo - Congestive Heart Failure, Heart Failure, Systolic | Phase 1 / Phase 2 | Recruiting | Sardocor Corp. | 57 | 2021-09-23 | 2024-03-26 |
| Treating Congestive HF With hiPSC-CMs Through Endocardial Injection hiPSC-CM therapy - Cardiovascular Diseases, Congestive Heart Failure | Phase 1 | Unknown | HELP Therapeutics Co., Ltd. | 20 | 2021-09-21 | 2022-09-23 |
| Acupuncture for the Treatment of Medication-Dependent Hypotension in Heart Failure True Acupuncture, Sham Acupuncture - Congestive Heart Failure, Hypotension | Phase 1 / Phase 2 | Unknown | Scripps Health | 40 | 2021-04-20 | 2021-07-07 |
| A Study to Learn How the Study Treatment BAY1753011 Moves Into, Through and Out of the Body, How it Works, How Safe it is, and How it Affects the Body When Given Once as Tablet in Male and Female Participants With Reduced Kidney Function Compared to Matched Participants With Normal Kidney Function Pecavaptan (BAY1753011) - Congestive Heart Failure, Renal Impairment | Phase 1 | Completed | Bayer | 32 | 2019-11-25 | 2022-10-31 |
| AB-1002 in Patients With Class III Heart Failure 3 x 10e13vg AB-1002 - Congestive Heart Failure, Heart Failure | Phase 1 | Completed | AskBio Inc | 11 | 2019-11-20 | 2026-08-06 |
| An Investigational Study of Experimental Medication BMS-986231 Given in Participants With Different Levels of Liver Function BMS-986231 - Liver Dysfunction, Liver Insufficiency | Phase 1 | Completed | Bristol-Myers Squibb | 76 | 2018-05-25 | 2020-08-27 |
| Accessing Mobility Using Wearable Sensors Exercise - COPD, Pulmonary Disease | Phase 1 / Phase 2 | Withdrawn | Baylor College of Medicine | 2018-05-21 | 2025-08-27 | |
| Phase I Study of OPC-61815 OPC-61815 16mg, OPC-61815 32mg, Moxifloxacin - Congestive Heart Failure | Phase 1 | Completed | Otsuka Pharmaceutical Co., Ltd. | 48 | 2018-05-08 | 2021-05-10 |
| Thiamine Supplementation in Heart Failure: a Pilot Randomized Controlled Crossover Trial Thiamine, Placebo - Heart Failure, Heart Failure With Reduced Ejection Fraction | Phase 1 | Completed | Hamilton Health Sciences Corporation | 24 | 2018-04-02 | 2021-08-31 |
| A Study of Experimental Medication BMS-986231 in Patients With Different Levels of Kidney Function BMS-986231 - Myocardial Failure, Cardiac Failure | Phase 1 | Completed | Bristol-Myers Squibb | 48 | 2018-03-15 | 2019-09-11 |
| Within Subject Variability Study of ER Torsemide 20 mg Tablet in Healthy Subjects Demadex 20mg Tablet, ER Torsemide 20mg Tablet - Congestive Heart Failure, Chronic Kidney Diseases | Phase 1 | Completed | Sarfez Pharmaceuticals, Inc. | 24 | 2017-06-19 | 2018-04-18 |
| AiDing Diuresis wIth Tolvaptan (ADD-IT) Tolvaptan 30 mg + IV Diuretics, Metolazone 5 mg + IV Diuretics, 2.5 times the Diuretics Dose - Cardiomyopathy, Congestive Heart Failure | Phase 1 | Completed | Emory University | 14 | 2016-01-01 | 2019-03-27 |
| A Study Investigating the Safety, Tolerability, and Pharmacokinetics of MTP-131 in Subjects With Congestive Heart Failure MTP-131, Placebo - Congestive Heart Failure | Phase 1 | Completed | Stealth BioTherapeutics Inc. | 36 | 2014-07-01 | 2015-09-17 |
| Study to Compare the Pharmacokinetic Characteristics and Safety of Dilatrend SR Capsule 32mg and Dilatrend Tablet 25mg Dilatrend SR capsule 32mg, Dilatrend IR tablet 25mg - Essential Hypertension, Chronic Stable Angina | Phase 1 | Unknown | Chong Kun Dang Pharmaceutical | 48 | 2013-04-01 | 2013-04-01 |
| Study of the Acute Effects of Triheptanoin in Heart Failure Triheptanoin oil - Congestive Heart Failure, Non-ischemic Cardiomyopathy | Phase 1 / Phase 2 | Withdrawn | University of Texas Southwestern Medical Center | 2013-02-01 | 2018-12-14 | |
| Autonomic Neural Regulation Therapy to Enhance Myocardial Function in Heart Failure (ANTHEM-HF) Study Vagus Nerve Stimulation (VNS) - Congestive Heart Failure | Phase 1 / Phase 2 | Completed | Cyberonics, Inc. | 60 | 2012-07-01 | 2015-02-19 |
| Cardiac Resynchronization and Iodine Meta-Iodobenzylguanidine (MIBG) Imaging 123 iodine metaiodobenzylguanidine - Congestive Heart Failure | Phase 1 | Terminated | Mayo Clinic | 14 | 2012-02-01 | 2017-04-26 |
| Tadalafil and Nesiritide as Therapy in Pre-clinical Heart Failure Nesiritide, Tadalafil, Placebo - Congestive Heart Failure | Phase 1 / Phase 2 | Completed | Mayo Clinic | 43 | 2012-02-01 | 2018-03-22 |
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Heart Failure (47) · Coronary Artery Disease (5) · Cardiovascular Diseases (4) · Myocardial Infarction (4) · Cardiomyopathies (3) · Renal Insufficiency (3) · Heart Diseases (2) · Heart Failure, Systolic (2) · Hypertension (2) · Myocardial Ischemia (2) · Pulmonary Disease, Chronic Obstructive (2) · Adenoviridae Infections (1) · Anemia (1) · Angina Pectoris (1) · Angina, Stable (1)
Heart Diseases (45) · Cardiovascular Diseases (43) · Vascular Diseases (12) · Pathological Conditions, Signs and Symptoms (11) · Pathologic Processes (9) · Myocardial Ischemia (7) · Arterial Occlusive Diseases (5) · Arteriosclerosis (5) · Coronary Disease (5) · Female Urogenital Diseases (4) · Female Urogenital Diseases and Pregnancy Complications (4) · Infarction (4) · Ischemia (4) · Kidney Diseases (4) · Male Urogenital Diseases (4)
Natriuretic Peptide, Brain (4) · Coronary Artery Bypass (2) · Sodium Chloride (2) · etamicastat (2) · Bosentan (1) · Carnitine (1) · Carvedilol (1) · Darbepoetin alfa (1) · Diuretics (1) · Exercise (1) · Extracorporeal Shockwave Therapy (1) · Furosemide (1) · KCB-1 protein, recombinant (1) · Metolazone (1) · Moxifloxacin (1)
Harvest Technologies (3) · Mayo Clinic (3) · Bial - Portela C S.A. (2) · Bioheart, Inc. (2) · Bristol-Myers Squibb (2) · Horng Chen (2) · Acusphere (1) · Amgen (1) · AskBio Inc (1) · Bayer (1) · Baylor College of Medicine (1) · China National Center for Cardiovascular Diseases (1) · Chong Kun Dang Pharmaceutical (1) · Copenhagen University Hospital, Rigshospitalet (1) · Cyberonics, Inc. (1)
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Amit Patel, MD (3) · Horng H Chen, MD (2) · Horng H. Chen, M.D. (2) · Andreas M Zeiher, MD (1) · Aslan T Turer, MD, MHS (1) · Bijan Najafi, PhD (1) · Chadwick Prodromos, MD (1) · Christopher Suhar, MD (1) · Christopher Wilcox, MD, PhD (1) · Clyde W Yancy, MD (1) · David Holmes, MD (1) · David R Murray, MD (1) · Dirk H Walter, MD (1) · Divya Gupta, MD (1)
PMID 11705426, PMID 22088800, PMID 22936827, PMID 22965994, PMID 22980293, PMID 23122795, PMID 23592107, PMID 24444305, PMID 25187002, PMID 25926562, PMID 26601770, PMID 27221316, PMID 27437887, PMID 29217757, PMID 30258648, PMID 31909303, PMID 33590355, PMID 34405565, PMID 35360224, PMID 41120766
P01HL076611 (3), UL1RR024150 (3), R01HL084155 (2), 2005 (1), 2017 (1), 2019 (1), P01HL066941 (1), R01HL036634 (1), R21DK081877 (1)