2 completed, 1 enrolling by invitation, 1 terminated. 4 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 2, Enrolling by invitation 1, Terminated 1 |
| Phase 2 | 4 | Completed 2, Enrolling by invitation 1, Terminated 1 |
Follow Horng Chen: new trials by email
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Enhancing the Natriuretic Peptide System in HFpEF MANP, Sacubitril/Valsartan, Oral Placebo - Heart Failure With Preserved Ejection Fraction, Chronic Kidney Diseases | Phase 1 / Phase 2 | Enrolling by invitation | Horng Chen | 60 | 2022-11-04 | 2025-10-09 |
| Natriuretic Peptide System as Therapy in Human Preclinical Left Ventricle Dysfunction Nesiritide, Placebo, Saline - Congestive Heart Failure | Phase 1 / Phase 2 | Completed | Horng Chen | 58 | 2006-02-01 | 2012-05-17 |
| Use of Nesiritide (BNP) in Kidney Function in Patients With Congestive Heart Failure (CHF) and Kidney Failure Nesiritide - Cardiorenal Syndrome | Phase 1 / Phase 2 | Terminated | Horng Chen | 4 | 2005-12-01 | 2017-11-06 |
| Cardiac Hormone Replacement With Brain Natriuretic Peptide (BNP) in Heart Failure B-type Natriuretic Peptide (BNP), Placebo - Congestive Heart Failure, Cardiomyopathy | Phase 1 / Phase 2 | Completed | Horng Chen | 45 | 2000-01-01 | 2012-12-20 |
Heart Failure (2) · Cardio-Renal Syndrome (1) · Cardiomyopathies (1) · Renal Insufficiency, Chronic (1)
Natriuretic Peptide, Brain (3) · Sodium Chloride (1) · sacubitril and valsartan sodium hydrate drug combination (1)
United States (4)
Horng H. Chen, M.D. (3) · Paul M McKie (1)
P01HL076611 (2), R01HL084155 (2), UL1RR024150 (2), R01HL036634 (1)