31 completed, 6 terminated, 4 unknown, 2 withdrawn. 44 Phase 3, 12 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 44 | Completed 31, Terminated 6, Unknown 4, Withdrawn 2, Recruiting 1 |
| Phase 2 | 12 | Completed 8, Unknown 3, Withdrawn 1 |
Follow Congestive Heart Failure: new trials by email Literature Review of Congestive Heart Failure trials Research Report on Congestive Heart Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Role of intraABDOminal Pressure and Point Of Care UltraSound to Guide Decongestive Therapy in Heart Failure Furosemide 20 Milligrams - Acute Heart Failure, Congestive Heart Failure | Phase 3 | Recruiting | Instituto de Investigación Sanitaria Aragón | 168 | 2025-03-10 | 2025-06-06 |
| Safety Trial of OPC-61815 Injection in Patients With Congestive Heart Failure Who Have Difficulty With or Are Incapable of Oral Intake OPC-61815 injection - Congestive Heart Failure | Phase 3 | Completed | Otsuka Pharmaceutical Co., Ltd. | 45 | 2019-06-17 | 2021-09-05 |
| Efficacy and Safety Trial of OPC-61815 Injection Compared With Tolvaptan 15-mg Tablet in Patients With Congestive Heart Failure OPC-61815, Tolvaptan Tab 15 MG - Congestive Heart Failure | Phase 3 | Completed | Otsuka Pharmaceutical Co., Ltd. | 294 | 2019-01-16 | 2021-08-05 |
| Inhaled Beta-adrenergic Agonists to Treat Pulmonary Vascular Disease in Heart Failure With Preserved EF (BEAT HFpEF): A Randomized Controlled Trial Albuterol, Saline placebo - Congestive Heart Failure, Heart Failure, Left-Sided | Phase 3 | Completed | Mayo Clinic | 30 | 2016-09-01 | 2019-02-22 |
| Sub-Q Versus IV Furosemide in Acute Heart Failure Furosemide Injection Solution (SCP-101), Furosemide Injection Solution, USP - Congestive Heart Failure | Phase 2 / Phase 3 | Completed | Johns Hopkins University | 40 | 2016-02-01 | 2017-12-18 |
| MADIT ASIA Cardiac Resynchronization Trial Two-lead CRT-P - Congestive Heart Failure, Left Bundle Branch Block | Phase 3 | Terminated | Boston Scientific Corporation | 1 | 2014-02-01 | 2014-04-30 |
| Optimised Pacing Program Enhanced standard management, Optimised heart failure management, Standard management - Pacemaker Complication, Congestive Heart Failure | Phase 3 | Unknown | University of Leeds | 1793 | 2013-08-01 | 2018-12-19 |
| A Pivotal Trial to Establish the Efficacy and Long-term Safety of the Parachute Implant System CardioKinetix Parachute Implant and All Appropriate Medical Therapy (AAMT) - Congestive Heart Failure, Left Ventricular (LV) Systolic Dysfunction | Phase 3 | Terminated | CardioKinetix, Inc | 331 | 2012-12-01 | 2017-06-23 |
| Comparative Study of Cardiopulmonary Exercise Test Land Versus Water Aerobic and anaerobic capacity use aquatic exercises - Congestive Heart Failure | Phase 2 / Phase 3 | Unknown | University of Sao Paulo General Hospital | 90 | 2011-04-01 | 2011-04-28 |
| Blood Pressure Reduction in Heart Failure Hydralazine/amlodipine, Placebo - Heart Failure, Cardiac Failure | Phase 2 / Phase 3 | Completed | University of Sao Paulo | 21 | 2011-01-01 | 2014-06-10 |
| Safety and Efficacy of Furosemide 40mg + Amiloride Hydrochloride 10mg to Reduct Edema Diurisa®, Lasix ® - Congestive Heart Failure | Phase 3 | Terminated | Eurofarma Laboratorios S.A. | 27 | 2011-01-01 | 2022-06-03 |
| Peritoneal Dialysis in Congestive Heart Failure icodextrin - Congestive Heart Failure | Phase 3 | Terminated | Martini Hospital Groningen | 26 | 2010-04-01 | 2019-08-16 |
| Safety and Efficacy of Low Dose Hypertonic Saline Solution and High Dose Furosemide for Congestive Heart Failure furosemide and hypertonic saline solution, furosemide - Congestive Heart Failure, Renal Insufficiency | Phase 3 | Completed | Aspirus Heart and Vascular Institute-Research and Education | 50 | 2009-11-01 | 2012-02-09 |
| Six Months Efficacy and Safety of Aliskiren Therapy on Top of Standard Therapy, on Morbidity and Mortality in Patients With Acute Decompensated Heart Failure Aliskiren, Placebo - Acute Decompensated Heart Failure, Congestive Heart Failure | Phase 3 | Completed | Novartis Pharmaceuticals | 1639 | 2009-05-01 | 2013-11-07 |
| Nebulized Albuterol for Congestive Heart Failure Exacerbation Albuterol, Normal Saline - Congestive Heart Failure | Phase 2 / Phase 3 | Withdrawn | University of California, San Francisco | 2009-04-01 | 2013-10-10 | |
| Influence of Pantoprazole on Human Myocardial Contractility at Patients With Congestive Heart Failure Pantoprazole - Congestive Heart Failure | Phase 3 | Withdrawn | Johann Wolfgang Goethe University Hospital | 2008-08-01 | 2014-02-11 | |
| Study to Assess the Safety and Tolerability of IV Tonapofylline in Subjects With Acute Decompensated Heart Failure (ADHF) and Renal Insufficiency tonapofylline, Placebo - Renal Insufficiency, Congestive Heart Failure | Phase 3 | Completed | Biogen | 420 | 2008-07-31 | 2023-09-11 |
| Efficiency Study of Triple-Site Cardiac Resynchronization in Patients With Heart Failure Cardiac resynchronization pacemaker (InSync Sentry or Concerto, Medtronic, Minneapolis, MN,USA) with two intracardiac leads, Triple-site cardiac resynchronization - Congestive Heart Failure, Heart Disease | Phase 2 / Phase 3 | Completed | Silesian Centre for Heart Diseases | 100 | 2008-02-01 | 2016-04-13 |
| To Assess Safety and Efficacy of Myoblast Implantation Into Myocardium Post Myocardial Infarction MyoCell, Hypothermosol - Congestive Heart Failure | Phase 2 / Phase 3 | Unknown | Bioheart, Inc. | 170 | 2007-09-01 | 2017-07-21 |
| Improving Clinician Communication Skills (ICCS) Training Program Intervention - Advanced Cancer, Chronic Obstructive Pulmonary Disease (COPD) | Phase 3 | Completed | University of Washington | 6086 | 2007-04-01 | 2014-09-16 |
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Heart Failure (44) · Ventricular Dysfunction (4) · Heart Diseases (3) · Renal Insufficiency (3) · Anemia (2) · Cardio-Renal Syndrome (2) · Cardiovascular Diseases (2) · Myocardial Infarction (2) · Pulmonary Disease, Chronic Obstructive (2) · Angina Pectoris (1) · Atrial Fibrillation (1) · Bundle-Branch Block (1) · Cardiomyopathies (1) · Diabetes Mellitus (1) · Dyspnea (1)
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Carvedilol (3) · Furosemide (3) · candesartan (3) · candesartan cilexetil (3) · Albuterol (2) · Darbepoetin alfa (2) · Natriuretic Peptide, Brain (2) · Sildenafil Citrate (2) · Tolvaptan (2) · 1,3-dipropyl-8-(2-(5,6-epoxy)norbornyl)xanthine (1) · Amlodipine (1) · BG 9928 (1) · Cardiac Resynchronization Therapy (1) · Continuous Positive Airway Pressure (1) · Defibrillators (1)
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PMID 37366061, PMID 19196892, PMID 25326006, PMID 29431256, PMID 31370950, PMID 33301080, PMID 36632831, PMID 15152059, PMID 16230259, PMID 17384437, PMID 17384438, PMID 17848651, PMID 18279770, PMID 18549913, PMID 18565860, PMID 18992654, PMID 19001508, PMID 19204305, PMID 20008582, PMID 20090057, PMID 20142024, PMID 20154234, PMID 20231531, PMID 20435194, PMID 21068341, PMID 21123186, PMID 21199833, PMID 21292991, PMID 21350053, PMID 21606084, PMID 21693723, PMID 21715583, PMID 21750125, PMID 21805159, PMID 21875912, PMID 22064591, PMID 22093207, PMID 22267751, PMID 22651239, PMID 22887722, PMID 22893340, PMID 23351825, PMID 23478743, PMID 23487543, PMID 23537969, PMID 23743487, PMID 24302090, PMID 24497345, PMID 24626998, PMID 24649963
2009 (2), R01HL126638 (1), R01HL128526 (1), R01NR009987 (1), U01HL125205 (1), U10HL110262 (1)