9 completed, 2 recruiting, 2 unknown. 4 Not applicable, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Completed 2, Recruiting 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
Follow Butyrylcholinesterase deficiency: new trials by email Literature Review of Butyrylcholinesterase deficiency trials Research Report on Butyrylcholinesterase deficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Serum Cholinesterases, Paraoxonase, and Cardiovascular Risk After Intravitreal Bevacizumab blood test - Diabete Mellitus, Retina Vein Occlusion | Recruiting | Ataturk University | 180 | 2025-11-03 | 2026-04-24 | |
| The Potential Protective Effect of Using Muscle Relaxants During Electroporation Ablation (PFA) Propofol, Rocuronium - Kidney Failure, Acute, Myopathy; Drugs | Not applicable | Recruiting | 4th Military Clinical Hospital with Polyclinic, Poland | 32 | 2024-08-01 | 2024-11-27 |
| High Flow Oxygen During Operative Hysteroscopy. Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE)., LMA - Endometrium; Hypertrophy, Cervix, Anesthesia | Not applicable | Completed | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 180 | 2022-06-17 | 2024-09-05 |
| Value of Butyrylcholinesterase as a Marker of Surgical Site Infection Following Surgery for Colorectal Diseases Butyrylcholinesterase - Colorectal Disorders, Colorectal Neoplasms | Completed | University Hospital of Patras | 400 | 2019-11-06 | 2023-06-15 | |
| Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Could Decrease the Incidence of Oxygen Desaturation During Suspension Laryngoscopy: a Randomized Controlled Trial (Optilaryngo) optiflow - Apnea, Postanesthetic, Desaturation of Blood | Not applicable | Completed | University Hospital, Caen | 80 | 2019-04-23 | 2022-02-18 |
| Race-Specific Propofol Titration to Effect for Procedural Sedation Titrate propofol monotherapy infusion to effect - Unconsciousness, Apnea, Postanesthetic | Completed | University of Florida | 2780 | 2018-01-05 | 2019-10-25 | |
| Comparison on Succinylcholine Onset Time Assessed by Train of Four Stimulation Versus Clinical Judgment During Rapid Sequence Induction of Anesthesia Suxamethonium Sensitivity, Aspiration of Gastric Contents Into Respiratory Tract, Part Unspecified | Unknown | University Hospital, Caen | 110 | 2017-11-06 | 2018-03-16 | |
| Point of Care Testing of Cholinesterase Activity During Burn- and Polytrauma Trauma, Burns | Completed | University Hospital Heidelberg | 85 | 2016-02-01 | 2019-04-16 | |
| Brain Changes by Rivastigmine According to Butyrylcholinesterase Alleles Rivastigmine - Alzheimer's Disease | Not applicable | Unknown | Seoul National University Hospital | 70 | 2014-02-01 | 2015-05-14 |
| Evaluation of Three Potential Central Nervous System (CNS) Pretreatments for Soman Exposure on Human Performance Huperzine A, Donepezil, Galantamine - Biomarkers, Pharmacological | Completed | U.S. Army Medical Research and Development Command | 84 | 2012-02-01 | 2017-05-03 | |
| Study to Investigate the Safety and Tolerability of AZD8848 in Butyrylcholinesterase Deficient Subjects AZD8848 - Butyrylcholinesterase Deficiency | Phase 1 | Completed | AstraZeneca | 22 | 2010-09-01 | 2015-08-14 |
| Use of Donepezil for Treatment of Cocaine Dependence Donepezil, 5 mg daily, Oral Placebo - Cocaine Abuse and Dependence | Phase 2 | Completed | US Department of Veterans Affairs | 12 | 2007-02-01 | 2014-06-09 |
| A Genetic and Perfusion Study of Response to Cognitive Enhancers in Lewy Body Disease Cholinesterase Inhibitors (Rivastigmine, Aricept, Galantamine) - Lewy Body Disease | Completed | Sunnybrook Health Sciences Centre | 57 | 2006-09-01 | 2016-04-13 |
Pain (3) · Acute Kidney Injury (1) · Alzheimer Disease (1) · Apnea (1) · Arrhythmias, Cardiac (1) · Burns (1) · Chronic Pain (1) · Cocaine-Related Disorders (1) · Colorectal Neoplasms (1) · Congenital Abnormalities (1) · Diabetes Mellitus (1) · Diabetic Retinopathy (1) · Hypertrophy (1) · Hypoxia (1)
Pathological Conditions, Signs and Symptoms (7) · Signs and Symptoms (6) · Neurologic Manifestations (5) · Nervous System Diseases (4) · Mental Disorders (3) · Brain Diseases (2) · Cardiovascular Diseases (2) · Central Nervous System Diseases (2) · Chemically-Induced Disorders (2) · Dementia (2) · Neurocognitive Disorders (2) · Neurodegenerative Diseases (2) · Signs and Symptoms, Respiratory (2) · Basal Ganglia Diseases (1) · Colonic Diseases (1)
Donepezil (3) · Galantamine (2) · Rivastigmine (2) · AZD8848 (1) · Anesthesia, General (1) · Butyrylcholinesterase (1) · Cholinesterase Inhibitors (1) · Hematologic Tests (1) · Propofol (1) · Rocuronium (1) · Tobacco Use Cessation Devices (1) · huperzine A (1)
University Hospital, Caen (2) · 4th Military Clinical Hospital with Polyclinic, Poland (1) · AstraZeneca (1) · Ataturk University (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Seoul National University Hospital (1) · Sunnybrook Health Sciences Centre (1) · U.S. Army Medical Research and Development Command (1) · US Department of Veterans Affairs (1) · University Hospital Heidelberg (1) · University Hospital of Patras (1) · University of Florida (1)
United States (3) · France (2) · Canada (1) · Denmark (1) · Germany (1) · Greece (1) · Italy (1) · Poland (1) · South Korea (1) · Turkey (Türkiye) (1)
Boutros Mariam (1) · Eleonore Mulac-Vauclair (1) · Jeffrey White, MD (1) · Jesper Sonne, MD (1) · Kamga Herve (1) · Kenneth Grasing, MD (1) · Marek Szamborski, MD (1) · Pierre-Emmanuel Marsan (1) · Sam Lindgren, MD, PhD (1) · Stefan Hofer, Prof. Dr. (1) · Stefan Kleinschmidt, Prof. Dr. (1)
PMID 13630833, PMID 19836169, PMID 20406507, PMID 23737548, PMID 25388828, PMID 25869405, PMID 26329355, PMID 27856714, PMID 27879385, PMID 28320364, PMID 28403407, PMID 29743098, PMID 30767199, PMID 31401603, PMID 31584919, PMID 32398433, PMID 32882605, PMID 32890016, PMID 35371356, PMID 40690380, PMID 6808323, PMID 7429910
UL1TR001427 (1)