Colonic Diseases: Clinical Trials

5060 completed, 1926 unknown, 1521 recruiting, 892 terminated. 3153 Not applicable, 2699 Phase 2, 1723 Phase 1, 989 Phase 3, 343 Phase 4.

By phase and status

Phase	Trials	Status
Not applicable	3153	Completed 1564, Unknown 567, Recruiting 428, Not yet recruiting 195, Terminated 151, Active not recruiting 122, Withdrawn 75, Enrolling by invitation 42, Suspended 9
Phase 2	2699	Completed 1109, Unknown 439, Recruiting 391, Terminated 343, Active not recruiting 158, Not yet recruiting 124, Withdrawn 117, Suspended 12, Enrolling by invitation 6
Phase 1	1723	Completed 767, Recruiting 281, Terminated 259, Unknown 159, Active not recruiting 119, Not yet recruiting 70, Withdrawn 54, Suspended 10, Enrolling by invitation 4
Phase 3	989	Completed 463, Unknown 189, Recruiting 118, Terminated 94, Active not recruiting 63, Not yet recruiting 33, Withdrawn 24, Enrolling by invitation 3, Suspended 2
Phase 4	343	Completed 172, Unknown 75, Terminated 28, Not yet recruiting 25, Recruiting 25, Withdrawn 10, Active not recruiting 6, Enrolling by invitation 2
Early Phase 1	113	Completed 30, Unknown 27, Recruiting 15, Not yet recruiting 13, Terminated 11, Withdrawn 7, Active not recruiting 6, Enrolling by invitation 2, Suspended 2

Follow Colonic Diseases: new trials by email Literature Review of Colonic Diseases trials Research Report on Colonic Diseases

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Dose Ranging Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Rectal Foam in Pediatric Patients Aged 5 to 17 Years With Active, Mild to Moderate Distal Ulcerative Colitis High dose budesonide rectal foam, Low dose budesonide rectal foam, Matching placebo rectal foam - Ulcerative Colitis	Phase 4	Not yet recruiting	Bausch Health Americas, Inc.	100	2029-06-01	2026-10-06
The Impact of a Patient Decision Aid on Treatment Choices for Patients With an Unexpected Malignant Colorectal Polyp Shared Decision Making using a Patient Decision Aid. - Shared Decision Making, Colonic Polyp	Phase 2	Not yet recruiting	Vejle Hospital	110	2028-02-01	2026-04-30
ACT for Veterans With IBD and Mental Health Challenges Acceptance and Commitment Therapy - Inflammatory Bowel Diseases, Crohn's Disease	Not applicable	Not yet recruiting	VA Office of Research and Development	50	2028-01-01	2026-02-09
CA102N Combined With TAS-102 Compared to Bevacizumab Combined With TAS-102 in Subjects With Metastatic Colorectal Cancer CA102N, TAS-102, Bevacizumab - Metastatic Colorectal Cancer	Phase 2	Suspended	Holy Stone Healthcare Co., Ltd	100	2027-12-01	2026-09-18
A Mindfulness-based Stress Reduction Program for IBD Mindfulness based stress reduction, Active Control - Inflammatory Bowel Disease (Crohn&Amp;#39;s Disease and Ulcerative Colitis)	Not applicable	Not yet recruiting	Nova Scotia Health Authority	70	2027-09-01	2026-09-08
Digital Mind Body Intervention Among Black and Hispanic Patients Living With Inflammatory Bowel Disease Digital Mind Body Intervention mobile application - Crohn's Disease, Ulcerative Colitis	Not applicable	Not yet recruiting	Montefiore Medical Center	40	2027-07-01	2026-09-14
Analysis of the Role of the Microbiota in Diverticular Disease Diverticular Disease of Colon, Acute Diverticulitis		Not yet recruiting	Hospital of Navarra	285	2027-06-01	2026-09-02
Adapted Physical Activity for Persistent Fatigue in Patients With Inflammatory Bowel Disease in Remission Adapted Physical Activity, Usual Care - Inflammatory Bowel Diseases (IBD), Fatigue	Not applicable	Not yet recruiting	University Hospital, Grenoble	120	2027-06-01	2026-09-11
SGA-OCRC: Prediction of 90-Day Major Adverse Postoperative Outcomes in Octogenarians With Resectable Colorectal Cancer Octogenarian Patients With Non-metastatic Resectable Colorectal Cancer		Not yet recruiting	Second Affiliated Hospital, Zhejiang University, School of Medicine	1000	2027-06-01	2026-10-29
Testing the Combination of Anti-Cancer Drugs, Botensilimab (AGEN1181) and Balstilimab (AGEN2034), After Standard Treatment for Colorectal Cancer, Combat Trial Balstilimab, Biopsy Procedure, Biospecimen Collection - Colorectal Adenocarcinoma, Stage II Colorectal Cancer AJCC v8	Phase 2	Recruiting	National Cancer Institute (NCI)	20	2027-05-25	2026-09-29
CCR5 Targeting Leronlimab in Combination With Hepatic Arterial Infusion Floxuridine and Systemic Therapy for the Treatment of Colorectal Cancer Liver Metastases, CHAMP Trial Biopsy Procedure, Biospecimen Collection, Computed Tomography - Metastatic Colorectal Carcinoma, Metastatic Malignant Neoplasm in the Liver	Phase 1	Not yet recruiting	City of Hope Medical Center	36	2027-05-06	2026-09-25
ASAPP Study - Topical 5-ASA as Prophylaxis for Pouchitis in Ulcerative Colitis Patients After Pelvic Pouch Surgery 5-ASA, Placebo - Ulcerative Colitis (UC), Pouchitis	Phase 4	Not yet recruiting	University Hospital, Linkoeping	110	2027-04-01	2026-08-19
Liver Transplantation for Non-Resectable Colorectal Liver Metastases Without Local Treatment Options Liver transplantation - Colorectal Neoplasms, Liver Neoplasms	Not applicable	Not yet recruiting	Charite University, Berlin, Germany	260	2027-04-01	2026-09-10
Cancer Awareness Among Syrian Migrants PMT-Based Cancer Screening Educational Intervention, PMT-Based Cancer Screening Education Program - Breast Cancer Screening, Cervical Cancer Screening	Not applicable	Not yet recruiting	Toros University	30	2027-03-09	2026-10-15
LMT503 First-in-human SAD, MAD, and FE Study LMT503, Placebo - Inflammatory Bowel Disease, Colitis, Ulcerative	Phase 1	Not yet recruiting	Lmito Therapeutics Inc.	72	2027-03-01	2026-09-01
Efficacy and Safety of TRA16 Administered Orally in Patients With Enteric Hyperoxaluria (EH). TRA16, Placebo - Enteric Hyperoxaluria	Phase 2	Not yet recruiting	Wuhan Kangfude Urolithiasis Research Institute Co., Ltd.	30	2027-03-01	2026-10-13
Life Expectancy-informed Colorectal Cancer Screening Decision Tool - Colorectal Cancer Control and Prevention	Not applicable	Not yet recruiting	Kathryn Martinez	15000	2027-03-01	2026-10-20
A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in Rectal Cancer Patients Dietary Fiber, Enema Administration, Loperamide Hydrochloride - Low Anterior Resection Syndrome, Rectal Carcinoma	Not applicable	Recruiting	Ohio State University Comprehensive Cancer Center	80	2027-02-15	2026-10-06
OSCAR II STUDY - The ONCObind CTC Removal Study ONCObind (Onco-Seraph) 100 Filter, Matched Controls - Pancreatic Ductal Adenocarcinoma (mPDAC), Metastatic Colorectal Carcinoma (mCRC)	Not applicable	Not yet recruiting	ExThera Medical Corporation	120	2027-01-15	2026-04-17
A Safety Study of ST316 in Participants With Familial Adenomatous Polyposis (FAP). ST316 IV - Familial Adenomatous Polyposis (FAP)	Phase 1	Not yet recruiting	Sapience Therapeutics	40	2027-01-04	2026-08-12

Showing 20 of 10948. Sign in to see all of them.

Narrower conditions

Colorectal Neoplasms (6126)  ·  Colonic Neoplasms (2382)  ·  Colitis, Ulcerative (1793)  ·  Rectal Neoplasms (1006)  ·  Irritable Bowel Syndrome (995)  ·  Breast Neoplasms (788)  ·  Inflammatory Bowel Diseases (731)  ·  Crohn Disease (702)  ·  Neoplasms (624)  ·  Pancreatic Neoplasms (598)  ·  Stomach Neoplasms (531)  ·  Carcinoma, Non-Small-Cell Lung (522)  ·  Neoplasm Metastasis (476)  ·  Lung Neoplasms (468)  ·  Ovarian Neoplasms (403)

Broader conditions

Digestive System Diseases (10865)  ·  Intestinal Diseases (10854)  ·  Gastrointestinal Diseases (10804)  ·  Neoplasms by Site (7889)  ·  Digestive System Neoplasms (7851)  ·  Intestinal Neoplasms (7847)  ·  Gastrointestinal Neoplasms (7727)  ·  Neoplasms (7335)  ·  Rectal Diseases (6527)  ·  Gastroenteritis (2055)  ·  Pathological Conditions, Signs and Symptoms (1898)  ·  Colorectal Neoplasms (1786)  ·  Colitis (1770)  ·  Pathologic Processes (1228)

Interventions

Fluorouracil (567)  ·  Oxaliplatin (532)  ·  Bevacizumab (527)  ·  Leucovorin (503)  ·  Irinotecan (464)  ·  Cetuximab (368)  ·  Capecitabine (365)  ·  pembrolizumab (170)  ·  Folfox protocol (147)  ·  Colonoscopy (140)  ·  Panitumumab (132)  ·  regorafenib (112)  ·  Mesalamine (97)  ·  Nivolumab (97)  ·  Drug Therapy (94)

Sponsors

National Cancer Institute (NCI) (192)  ·  Fudan University (121)  ·  M.D. Anderson Cancer Center (113)  ·  Sun Yat-sen University (95)  ·  Hoffmann-La Roche (93)  ·  Memorial Sloan Kettering Cancer Center (93)  ·  Pfizer (93)  ·  Mayo Clinic (63)  ·  Assistance Publique - Hôpitaux de Paris (62)  ·  AbbVie (60)  ·  Takeda (60)  ·  Chinese University of Hong Kong (59)  ·  Eli Lilly and Company (59)  ·  City of Hope Medical Center (58)  ·  Massachusetts General Hospital (55)

Countries

United States (3851)  ·  China (1410)  ·  France (978)  ·  Italy (790)  ·  Canada (763)  ·  Spain (727)  ·  United Kingdom (720)  ·  Germany (682)  ·  Belgium (506)  ·  South Korea (502)  ·  Netherlands (490)  ·  Australia (397)  ·  Poland (383)  ·  Denmark (358)  ·  Japan (317)

Top investigators

Norman Wolmark, MD (20)

Results publications

PMID 40243391, PMID 36306483, PMID 35588252, PMID 37162250, PMID 40013523, PMID 31268130, PMID 32445184, PMID 33356421, PMID 35648151, PMID 36124702, PMID 24275240, PMID 26049686, PMID 28712102, PMID 29850873, PMID 30476584, PMID 30679026, PMID 31077827, PMID 31378656, PMID 31599001, PMID 32816215, PMID 32816630, PMID 33684552, PMID 35792493, PMID 36342120, PMID 36526796, PMID 36931693, PMID 38425446, PMID 39778975, PMID 9146781, PMID 18316791, PMID 19339720, PMID 21997132, PMID 22070868, PMID 26893500, PMID 27144617, PMID 28705783, PMID 32085892, PMID 32766762, PMID 32870265, PMID 32964215, PMID 33127596, PMID 33324993, PMID 33513294, PMID 33657038, PMID 34353864, PMID 34614208, PMID 35380664, PMID 35380740, PMID 36336750, PMID 36748942

NIH funding

2023 (85), 2025 (67), 2017 (61), 2016 (49), 2018 (43), 2019 (41), 2015 (38), 2009 (32), P30CA033572 (28), 2014 (26), P30CA015083 (25), 2008 (24), P30CA014089 (21), P30CA016672 (15), P30CA068485 (15)