18 unknown. 18 Phase 1, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 18 | Unknown 18 |
| Phase 2 | 7 | Unknown 7 |
Follow Brain Injuries: new trials by email Literature Review of Brain Injuries trials Research Report on Brain Injuries
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating the Effect of Tranexamic Acid on the Clinical Outcomes in Patients With Traumatic Brain Injury Tranexamic Acid (TXA), Normal saline - Traumatic Brain Injury | Phase 1 / Phase 2 | Unknown | Mansoura University | 90 | 2024-03-25 | 2024-05-10 |
| Tau And Connectomics In TES Study [18F] PI-2620 Tau Ligand - Chronic Traumatic Encephalopathy, Traumatic Encephalopathy | Phase 1 | Unknown | Macquarie University, Australia | 12 | 2023-02-03 | 2024-02-28 |
| To Evaluate the Effect of Glibenclamide in Reducing Brain Edema of TBI glibenclamide - Traumatic Brain Injury | Phase 1 / Phase 2 | Unknown | Beijing Tiantan Hospital | 76 | 2021-10-22 | 2021-12-08 |
| ATCell™ Expanded Autologous, Adipose-Derived Mesenchymal Stem Cells Deployed Via Intravenous Infusion 50 Adipose Derived Stem Cell Infusion, 150 Adipose Derived Stem Cell Infusion, 300 Adipose Derived Stem Cell Infusion - Post-Concussion Syndrome | Phase 1 | Unknown | American CryoStem Corporation | 20 | 2021-02-01 | 2023-06-09 |
| Exploring the Utility of [18F]3F4AP for Demyelination Imaging in Controls, Neurodegeneration and Traumatic Brian Injury F18-3F4AP - Brain Injuries, Traumatic, Demyelinating Disorder | Phase 1 | Unknown | Massachusetts General Hospital | 8 | 2021-01-25 | 2024-01-30 |
| Autologous Umbilical Cord Blood Treatment of Neonate With CHD Autlogous UCB infusion - Congenital Heart Disease, Brain Injuries | Phase 1 / Phase 2 | Unknown | Sheba Medical Center | 60 | 2019-02-01 | 2021-01-20 |
| The Treatment of Premature Infants With Brain Injury by Autologous Umbilical Cord Blood Stem Cells autologous umbilical cord blood stem cells, 0.9% Sodium-chloride - Safety Issues, Effect of Drugs | Phase 1 | Unknown | Guangdong Women and Children Hospital | 200 | 2018-11-01 | 2018-10-05 |
| Fibrinogen Concentrate in Isolated Traumatic Brain Injury RiaSTAP Injectable Product - Traumatic Brain Injury, Hemorrhage | Phase 1 / Phase 2 | Unknown | Leila Dehghani | 50 | 2018-10-23 | 2019-02-27 |
| Exercise and Rehabilitation After Traumatic Brain Injury Aerobic Exercise (AER), Rehabilitation - Traumatic Brain Injury | Phase 1 | Unknown | Centre for Neuro Skills | 120 | 2016-06-01 | 2018-01-30 |
| Injectable Collagen Scaffold™ Combined With MSCs Transplantation for Brain Injury Stereotactic Hematoma Evacuation, MSCs Transplantation, Injectable Collagen Scaffold with MSCs Transplantation - Brain Injury | Phase 1 | Unknown | Chinese Academy of Sciences | 30 | 2016-03-01 | 2020-12-23 |
| A Study of IBRF Disorders of Consciousness Advanced Care/MultiModal Care Protocol in Severe Disorders of Consciousness Polypharmacy using FDA-approved products, Median Nerve Stimulation (MNS), Nutraceutical Supplementation - Brain Injury | Phase 1 / Phase 2 | Unknown | International Brain Research Foundation | 30 | 2016-03-01 | 2016-09-02 |
| Traumatic Neuroprotection and Epilepsy Prevention of Valproate Acid valproate acid - Traumatic Brain Injury | Phase 1 | Unknown | Xijing Hospital | 160 | 2013-10-01 | 2014-01-06 |
| Controlled Trial of ABELADRUG200 in Closed, Severe Head Injury AbelaDrug200, mannitol - Severe Head Trauma | Phase 1 / Phase 2 | Unknown | Abela Pharmaceuticals, Inc. | 30 | 2010-10-01 | 2010-12-08 |
| Study of Fludarabine + Cyclophosphamide + TBI Conditioning Regimen for Double Units Cord Blood Transplantation(CBT)in Severe Aplastic Anemia(SAA) Cyclophosphosphamide, TBI - Aplastic Anemia | Phase 1 / Phase 2 | Unknown | The Korean Society of Pediatric Hematology Oncology | 5 | 2008-11-01 | 2012-03-26 |
| Hyperbaric Oxygen Therapy and SPECT Brain Imaging in Traumatic Brain Injury Hyperbaric oxygen therapy - Residual Neurological, Cognitive, Emotional, Behavioral Effects From Traumatic Brain Injury | Phase 1 | Unknown | Paul G. Harch, M.D. | 45 | 2007-01-01 | 2017-04-18 |
| Induction of Mixed Hemopoietic Chimerism in Patients Using Fludarabine, Low Dose TBI, PBSC Infusion and Post Transplant in Immunosuppression w/CSA & Mycophenolate Mofetil Mycophenolate Mofetil - Post Transplant in Immunosuppression w/CSA & Mycophenolate Mofetil | Phase 1 | Unknown | King Faisal Specialist Hospital & Research Center | 350 | 2002-07-01 | 2011-12-13 |
| Oxygen Toxicity of HBOT in Chronic Brain Injury Hyperbaric oxygen therapy - Adult and Pediatric Chronic Cerebral Disorders | Phase 1 | Unknown | Paul G. Harch, M.D. | 45 | 2002-04-01 | 2015-01-05 |
| Excitatory Amino Acids and Activated Microglia After Traumatic Brain Injury: a (R)-[11C]PK11195 PET Study Positron Emission Tomography - Traumatic Brain Injury | Phase 1 | Unknown | Amsterdam UMC, location VUmc | 20 | 2001-05-01 | 2005-11-04 |
Brain Injuries, Traumatic (13) · Alzheimer Disease (1) · Anemia, Aplastic (1) · Brain Concussion (1) · Brain Diseases (1) · Cardiac Output, Low (1) · Chronic Traumatic Encephalopathy (1) · Cognitive Dysfunction (1) · Coma (1) · Consciousness Disorders (1) · Craniocerebral Trauma (1) · Demyelinating Diseases (1) · Epilepsy (1) · Head Injuries, Closed (1)
Central Nervous System Diseases (18) · Nervous System Diseases (18) · Trauma, Nervous System (18) · Wounds and Injuries (18) · Brain Diseases (17) · Craniocerebral Trauma (17) · Pathological Conditions, Signs and Symptoms (4) · Mental Disorders (3) · Neurocognitive Disorders (3) · Brain Damage, Chronic (2) · Pathologic Processes (2) · Signs and Symptoms (2) · Wounds, Nonpenetrating (2) · Anemia (1)
Hyperbaric Oxygenation (2) · Exercise (1) · Flumazenil (1) · Glyburide (1) · Lacteol (1) · Lamotrigine (1) · Mannitol (1) · Minocycline (1) · Mycophenolic Acid (1) · Positron-Emission Tomography (1) · Rehabilitation (1) · Saline Solution (1) · Sodium Chloride (1) · Standard of Care (1) · Thioctic Acid (1)
Paul G. Harch, M.D. (2) · Abela Pharmaceuticals, Inc. (1) · American CryoStem Corporation (1) · Amsterdam UMC, location VUmc (1) · Beijing Tiantan Hospital (1) · Centre for Neuro Skills (1) · Chinese Academy of Sciences (1) · Guangdong Women and Children Hospital (1) · International Brain Research Foundation (1) · King Faisal Specialist Hospital & Research Center (1) · Leila Dehghani (1) · Macquarie University, Australia (1) · Mansoura University (1) · Massachusetts General Hospital (1) · Sheba Medical Center (1)
United States (7) · China (3) · Australia (1) · Egypt (1) · Iran (1) · Israel (1) · Netherlands (1) · Saudi Arabia (1) · South Korea (1)
Paul G Harch, M.D. (2) · Bart van Berckel, MD; PhD (1) · Fei Zhou, M.D., Ph.D. (1) · Grace S Griesbach, PhD (1) · Hyo Seop Ahn, M.D, Ph.D (1) · Jianwu Dai, Ph.D (1) · Jie Yang, PHD (1) · Mahmoud Aljurf, MD (1) · Marc Normandin, PhD (1) · Peter B Hanson, MD (1) · Philip A Defina, Ph.D. (1) · Rowena Mobbs, MBBS, PhD (1)