11 completed, 7 recruiting, 5 unknown, 2 withdrawn. 6 Not applicable, 4 Phase 2, 3 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Recruiting 3, Unknown 2, Completed 1 |
| Phase 2 | 4 | Completed 3, Unknown 1 |
| Phase 1 | 3 | Completed 2, Unknown 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Chronic Traumatic Encephalopathy: new trials by email Literature Review of Chronic Traumatic Encephalopathy trials Research Report on Chronic Traumatic Encephalopathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cerebral and Cognitive Impact of Female Professional SoccerPractice Cerebral MRI - Traumatic Chronic Encephalopathy | Not applicable | Recruiting | University Hospital, Strasbourg, France | 80 | 2025-09-13 | 2026-08-20 |
| Visualizing Brain Proteinopathies Using [F-18]Flornaptitril-PET in the Prediction of Clinical Progression of Mild Cognitive Impairment With Either Suspected Chronic Traumatic Encephalopathy or Alzheimer's Disease [F-18]Flornaptitril - Alzheimer Disease, Chronic Traumatic Encephalopathy | Phase 3 | Recruiting | CereMark Pharma, LLC | 230 | 2025-07-01 | 2025-07-30 |
| The DIAGNOSE CTE Research Project-II Chronic Traumatic Encephalopathy (CTE), Alzheimer Disease | Enrolling by invitation | Boston University | 350 | 2025-04-09 | 2026-06-02 | |
| Pilot Study Evaluating brainQuant's Ability to Detect Alterations in White Matter in Diffusion MRI, Indicative of Post-traumatic Lesions Chronic Traumatic Encephalopathy | Recruiting | University Hospital, Strasbourg, France | 80 | 2024-09-10 | 2025-12-24 | |
| Heading in Football: Impact on Neural Blood Biomarkers Head impact exposure - Head Injury, Minor, Concussion, Mild | Completed | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 335 | 2024-08-13 | 2025-05-13 | |
| Tau And Connectomics In TES Study [18F] PI-2620 Tau Ligand - Chronic Traumatic Encephalopathy, Traumatic Encephalopathy | Phase 1 | Unknown | Macquarie University, Australia | 12 | 2023-02-03 | 2024-02-28 |
| Cerebral and Cognitive Impact of Professional Soccer Practice MRI - Traumatic Chronic Encephalopathy | Not applicable | Recruiting | University Hospital, Strasbourg, France | 80 | 2022-01-07 | 2025-08-08 |
| Long-term Follow-up in Severe Traumatic Brain Injury Magnetic Resonance Imaging (MRI) (including functional MRI), Blood sampling (serum/plasma preparation), Cerebrospinal fluid (CSF) - Traumatic Brain Injury, Neurodegenerative Diseases | Unknown | Karolinska University Hospital | 100 | 2021-10-01 | 2022-02-11 | |
| Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD) No Intervention is used for this study but all subjects will be asked to complete electroencephalogram (EEG) testing and an MRI scan., No intervention is used for this study but all subjects will be asked to complete a venous blood draw procedure and a lumbar puncture procedure. - Mild Traumatic Brain Injury, Moderate Traumatic Brain Injury | Recruiting | VA Office of Research and Development | 800 | 2021-07-01 | 2026-09-01 | |
| FDDNP Protocol for Visualizing Brain Proteinopathies to Assist in the Diagnosis of Persons With Suspected CTE and AD [F-18]FDDNP-PET - Suspected Chronic Traumatic Encephalopathy (CTE) or Traumatic Encephalopathy Syndrome (TES), Suspected Alzheimer's Disease (AD) | Withdrawn | University of California, Los Angeles | 2021-05-01 | 2021-05-06 | ||
| Cohort Study of Blood Biomarkers for TES Blood tests, Cognitive function tests, head MRI (plain scan and DTI sequence) examination and head PET (FDG-PET, Tau-PET and Amyloid-PET) examination - Chronic Traumatic Encephalopathy, Traumatic Encephalopathy, Chronic | Completed | Tianjin Medical University | 120 | 2021-05-01 | 2026-01-12 | |
| Near-Infrared Laser Stimulation for Various Neurological Conditions Near Infrared Laser Stimulation - Refractory Depression, Anxiety Disorders | Not applicable | Unknown | Neurological Associates of West Los Angeles | 400 | 2021-01-02 | 2022-09-28 |
| The Effects of Fish Oil Supplementation on the Brain Health of Collegiate Football Athletes Fish Oil (DPA+EPA 2:1 ratio) Capsules, High Oleic Safflower Oil Capsules - Traumatic Brain Injury (TBI), Chronic Traumatic Encephalopathy (CTE) | Not applicable | Completed | University of Arizona | 38 | 2019-05-28 | 2025-05-09 |
| Outcomes Mandate National Integration With Cannabis as Medicine Cannabis, Medical, RYAH-Medtech Inhaler - Chronic Pain, Chronic Pain Syndrome | Phase 2 | Unknown | OMNI Medical Services, LLC | 200000 | 2018-12-01 | 2022-06-02 |
| Alzheimer's Autism and Cognitive Impairment Stem Cell Treatment Study Intravenous Bone Marrow Stem Cell (BMSC) Fraction, Intranasal Topical Bone Marrow Stem Cell (BMSC) Fraction, Near Infrared Light - Alzheimer Disease, Alzheimer Dementia | Not applicable | Unknown | MD Stem Cells | 100 | 2018-10-24 | 2024-04-15 |
| The DIAGNOSE-CTE Research Project Chronic Traumatic Encephalopathy | Completed | Boston University | 240 | 2016-08-01 | 2023-12-05 | |
| Neurologic Stem Cell Treatment Study Intravenous and Intranasal BMSC - Neurologic Disorders, Nervous System Diseases | Not applicable | Recruiting | MD Stem Cells | 500 | 2016-06-01 | 2026-06-26 |
| Intranasal Inhalations of Bioactive Factors Produced by M2 Macrophages in Patients With Organic Brain Syndrome Intranasal auto-M2-BFs - Organic Brain Syndrome, Nonpsychotic, Neurocognitive Disorders | Phase 1 / Phase 2 | Completed | Russian Academy of Medical Sciences | 30 | 2016-03-01 | 2021-02-18 |
| Tau Imaging of Chronic Traumatic Encephalopathy [F18]-T807, [F18]-Florbetapir, MRI/MRS - Chronic Traumatic Encephalopathy | Phase 2 | Completed | Brigham and Women's Hospital | 30 | 2015-01-01 | 2018-05-17 |
| Amyloid and Tauopathy PET Imaging in Acute and Chronic Traumatic Brain Injury Amyvid PET Scan, T807 PET scan - Traumatic Brain Injury, Chronic Traumatic Encephalopathy | Completed | Samuel Gandy | 46 | 2015-01-01 | 2019-05-02 |
Showing 20 of 26. Sign in to see all of them.
Brain Injuries, Traumatic (12) · Alzheimer Disease (8) · Cognitive Dysfunction (6) · Neurodegenerative Diseases (4) · Brain Concussion (3) · Dementia (3) · Nerve Degeneration (3) · Parkinson Disease (3) · Pick Disease of the Brain (3) · Amyotrophic Lateral Sclerosis (2) · Anxiety Disorders (2) · Autistic Disorder (2) · Brain Ischemia (2) · CADASIL (2)
Brain Damage, Chronic (26) · Brain Injury, Chronic (26) · Central Nervous System Diseases (26) · Chronic Disease (26) · Disease Attributes (26) · Pathologic Processes (26) · Pathological Conditions, Signs and Symptoms (26) · Trauma, Nervous System (26) · Wounds and Injuries (26) · Brain Diseases (25) · Brain Injuries (25) · Craniocerebral Trauma (25) · Nervous System Diseases (25) · Neurodegenerative Diseases (22) · Mental Disorders (15)
7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole (4) · florbetapir (4) · Magnetic Resonance Imaging (2) · Blood Specimen Collection (1) · Capsules (1) · Cerebrospinal Fluid Pressure (1) · Diffusion Tensor Imaging (1) · Electroencephalography (1) · Fish Oils (1) · Genetic Testing (1) · Hematologic Tests (1) · Magnetic Resonance Spectroscopy (1) · Medical Marijuana (1) · Physical Examination (1) · tau Proteins (1)
University Hospital, Strasbourg, France (3) · Boston University (2) · MD Stem Cells (2) · University of California, Los Angeles (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Avid Radiopharmaceuticals (1) · Brigham and Women's Hospital (1) · CereMark Pharma, LLC (1) · Karolinska University Hospital (1) · Macquarie University, Australia (1) · Molecular NeuroImaging (1) · Neurological Associates of West Los Angeles (1) · OMNI Medical Services, LLC (1) · Russian Academy of Medical Sciences (1) · Samuel Gandy (1)
United States (15) · France (3) · United Arab Emirates (2) · Australia (1) · Canada (1) · China (1) · Israel (1) · Netherlands (1) · Russia (1) · Sweden (1)
Jeffrey Weiss, MD (2) · Steven Levy, MD (2) · Alexander A Ostanin, MD, PhD (1) · Chad Yucus, MD (1) · Charles H Tator, M.D (1) · Danna Jennings, MD (1) · Dara Dickstein, PhD (1) · Dr. Ryan O Lakin, MD JD (1) · Elena R Chernykh, MD, PhD (1) · Floyd Chilton, Ph.D. (1) · Gary W Small, M.D. (1) · Helen Lavretsky, MD (1) · Jaap Oosterlaan, Prof.Dr. (1)
PMID 23343487, PMID 25848027, PMID 29136240, PMID 30040711, PMID 30969506, PMID 34384490, PMID 36188406, PMID 36351716, PMID 37798671, PMID 38134231
R01NS139383 (1), U01NS093334 (1)