40 completed, 24 recruiting, 18 unknown, 17 terminated. 77 Not applicable, 8 Phase 4, 3 Phase 2, 1 Phase 1, 1 Phase 3.
Follow Spinal Cord Stimulation: new trials by email Literature Review of Spinal Cord Stimulation trials Research Report on Spinal Cord Stimulation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Neuromodulation to Overcome Severe Restless Legs Syndrome Spinal Cord Stimulation - Restless Leg Syndrome (RLS), Spinal Cord Stimulation (SCS) | Not applicable | Not yet recruiting | Marshall Holland | 15 | 2027-10-01 | 2026-10-09 |
| Transcutaneous Spinal Cord Stimulation for Blood Pressure Augmentation Immediately After Spinal Cord Injury Spinal Cord Stimulation - Spinal Cord Injury Cervical, Spinal Cord Injuries (SCI) | Not applicable | Not yet recruiting | Markey Olson | 20 | 2026-12-01 | 2026-10-21 |
| Prospective Evaluation of the Optimal SCS Trial Length Spinal Cord Stimulation (SCS) Trial - Spinal Cord Stimulation | Not yet recruiting | Ohio State University | 42 | 2026-10-28 | 2026-10-06 | |
| Efficacy of Spinal Cord Stimulation in Chemotherapy-Induced Peripheral Neuropathy Spinal cord stimulation (FAST mode), Sham Spinal Cord Stimulation - Neuropathic Pain, Chemotherapy-induced Peripheral Neuropathy (CIPN) | Not applicable | Not yet recruiting | Assistance Publique Hopitaux De Marseille | 68 | 2026-09-01 | 2026-05-12 |
| Spinal Cord Stimulation Combined With Motor Imagery Brain-Computer Interface for Chronic Post-Stroke Upper Limb Motor Dysfunction Spinal Cord Stimulation, Motor Imagery Brain-Computer Interface Rehabilitation Training - Chronic Stroke | Not applicable | Not yet recruiting | Zhejiang Provincial People's Hospital | 66 | 2026-09-01 | 2026-07-07 |
| PULmonary Stimulation for Asthma Relief Spinal Cord Stimulation - Moderate to Severe Asthma | Not applicable | Recruiting | Spiro Medical, Inc. | 30 | 2026-08-30 | 2026-10-13 |
| Short-term Spinal Stimulation Effects in Cerebral Palsy Spinal Stimulation, Treadmill Walking - Cerebral Palsy | Not applicable | Recruiting | University of Washington | 20 | 2026-08-13 | 2026-09-17 |
| Home-based Spinal Cord Stimulation for Hand & Arm Function in MS Spinal Cord Stimulation + Hand/arm Exercises - Multiple Sclerosis | Not applicable | Enrolling by invitation | University of Washington | 2 | 2026-07-16 | 2026-06-29 |
| Study on the Efficacy of Spinal Cord Stimulation in Patients With Severe Refractory Primary or Secondary RLS Spinal cord stimulation (SCS), Sham stimulation - Restless Leg Syndrome (RLS) | Not applicable | Not yet recruiting | Clinica ARS Medica | 15 | 2026-06-01 | 2026-05-06 |
| An Integrated Intervention of Spinal Cord Stimulation and Multidisciplinary Rehabilitation for Chronic Neuropathic Leg Pain: A Single-case Experimental Design Protocol Treatment bundle - Neuropathic Pain, Multidisciplinary Approach | Not applicable | Recruiting | Oslo University Hospital | 10 | 2026-05-04 | 2026-10-16 |
| Rehab and Mechanical Ventilation Spinal cord stimulation, Inspiratory Strength Training, Sham Stimulation - Inspiratory Strength Training (IST), Transcutaneous Spinal Stimulation | Not applicable | Recruiting | University of Florida | 16 | 2026-03-30 | 2026-05-05 |
| Sensory Spinal Cord Stimulation Spinal cord stimulation (SCS) - Pain Management, Pain, Intractable | Not applicable | Recruiting | University of North Carolina, Chapel Hill | 10 | 2026-01-06 | 2026-02-04 |
| Open and Closed Loop DTM SCS in Patients With PSPS Type 2: ENDLESS Study Spinal Cord Stimulation - Persistent Spinal Pain Syndrome Type 2, Failed Back Surgery Syndrome | Recruiting | Universitair Ziekenhuis Brussel | 200 | 2025-12-12 | 2026-08-17 | |
| EVA: Evaluation of EVOKE Therapy Metrics Generated Using the Evoke System With EVA Spinal Cord Stimulation (SCS) System - Chronic Pain | Not yet recruiting | Dustin Reynolds, MD | 40 | 2025-11-30 | 2025-12-05 | |
| Ultrasound for Quantifying Muscle Activation Elicited by Spinal Cord Stimulation and Functional Electrical Stimulation Functional Electrical Stimulation, Transcutaneous (Non-Invasive) Spinal Cord Stimulation, Ultrasound - Neuromodulatory Effects of TSCS and FES in Lower Limbs | Not applicable | Recruiting | North Carolina State University | 30 | 2025-06-01 | 2025-10-14 |
| Testing Non-Invasive Spinal Stimulation Devices Spinal Stimulation - Healthy Participants | Not applicable | Recruiting | Gail Forrest | 10 | 2025-05-29 | 2026-05-20 |
| Epidural Spinal Cord Stimulation for Lower-limb Impairment in Adrenomyeloneuropathy Spinal cord stimulation - Adrenomyeloneuropathy Without Cerebral Involvement | Not applicable | Recruiting | Third Military Medical University | 10 | 2025-02-10 | 2025-01-28 |
| Spinal Cord Stimulation for Freezing of Gait in Parkinson's Disease Spinal Cord Stimulation, Spinal electrophysiological recordings - Freezing of Gait, Parkinson Disease | Phase 2 | Active not recruiting | Universitaire Ziekenhuizen KU Leuven | 29 | 2025-02-05 | 2026-09-21 |
| Neurophysiological Effects of Medication Tapering During Treatment With Spinal Cord Stimulation Spinal Cord Stimulation with Evoke Closed-Loop System - Persistent Spinal Pain Syndrome Type 2 (PSPS-T2), Lower Spine, Spinal Cord Sensitivity to Neurostimulation | Recruiting | Brai²n | 50 | 2025-02-03 | 2026-02-17 | |
| SCS for Patient With Painful Diabetic Neuropathy and Peripheral Arterial Disease Spinal cord stimulation, Sham stimulation - Peripheral Arterial Disease, Painful Diabetic Neuropathy | Not applicable | Recruiting | University of Nebraska | 15 | 2024-12-18 | 2025-10-22 |
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Chronic Pain (35) · Failed Back Surgery Syndrome (17) · Neuralgia (16) · Pain (14) · Back Pain (11) · Low Back Pain (8) · Pain, Intractable (8) · Spinal Cord Injuries (7) · Parkinson Disease (6) · Angina Pectoris (4) · Diabetic Neuropathies (3) · Pain, Postoperative (3) · Cerebral Palsy (2) · Complex Regional Pain Syndromes (2) · Gait Disorders, Neurologic (2)
Boston Scientific Corporation (7) · Abbott Medical Devices (6) · MedtronicNeuro (6) · Saluda Medical Pty Ltd (5) · Barts & The London NHS Trust (3) · Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health (3) · University of Washington (3) · Brai²n (2) · Huashan Hospital (2) · Maastricht University Medical Center (2) · Mayo Clinic (2) · Poitiers University Hospital (2) · Sahlgrenska University Hospital (2) · Skolkovo Institute of Science and Technology (2) · St. Olavs Hospital (2)
United States (42) · Belgium (15) · Netherlands (12) · China (9) · United Kingdom (9) · France (6) · Germany (6) · Russia (6) · Spain (6) · Canada (5) · Norway (5) · Sweden (5) · Italy (4) · Australia (3) · Denmark (3)
Roshini Jain (3) · Evgeny N Mikhaylov, Assoc.prof. (2) · Kliment Gatzinsky, MD, PhD (2) · Natalie Bloom Lyons (2) · Sasha Gulati, md prof (2) · Vivek Mehta (2) · Adnan Al-Kaisy, MD (1) · Alexander Herman, MD, PhD (1) · Alexander Kaplan, D.Sci., Ph.D. (1) · Amol Yadav, PhD (1) · Ann Ver Donck, MD PhD (1) · Anthony F. DiMarco, MD (1) · Antonios Mammis, MD (1)
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1UG3NS145980-01 (1), 2009 (1), 2023 (1), 7DP2NS136872-02 (1), R01AT010817 (1), R21HD121135 (1)