19 completed, 6 unknown, 3 recruiting, 3 terminated. 33 Phase 2, 8 Phase 3, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 33 | Completed 19, Unknown 6, Recruiting 3, Terminated 3, Withdrawn 2 |
| Phase 3 | 8 | Completed 5, Unknown 2, Recruiting 1 |
| Phase 1 | 2 | Completed 1, Recruiting 1 |
Follow Aortic Aneurysm: new trials by email Literature Review of Aortic Aneurysm trials Research Report on Aortic Aneurysm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| HEART: Pilot Randomized Controlled Trial Spironolactone, Placebo - Thoracic Aortic Aneurysm | Phase 1 / Phase 2 | Recruiting | Mayo Clinic | 50 | 2026-05-25 | 2026-06-08 |
| Abdominal Aortic Aneurysm Stabilization With Truncal Cells: Controlled Clinical Trial With Historical Cohorts Allogeneic adipose tissue-derived mesenchymal stem cells - Aortic Aneurysm, Abdominal | Phase 2 | Unknown | Instituto de Investigación Hospital Universitario La Paz | 8 | 2024-06-13 | 2024-07-08 |
| Nectero EAST System Clinical Study Nectero EAST System - Abdominal Aortic Aneurysm | Phase 2 / Phase 3 | Recruiting | Nectero Medical, Inc. | 400 | 2023-10-25 | 2026-09-28 |
| Limiting AAA With Metformin (LIMIT) Trial Metformin, Placebo - Abdominal Aortic Aneurysm | Phase 2 | Recruiting | Stanford University | 314 | 2022-02-28 | 2025-04-18 |
| Ketamine in Patients Undergoing TEVAR Procedures Receiving NCI Saline, Ketamine - Descending Aortic Dissection, Postoperative Pain | Phase 2 | Completed | Eric Johnson | 21 | 2020-12-08 | 2026-09-21 |
| Metformin for Abdominal Aortic Aneurysm Growth Inhibition Metformin, Standard care - Abdominal Aortic Aneurysm | Phase 2 | Unknown | Uppsala University Hospital | 500 | 2020-02-12 | 2023-09-06 |
| Targeted PET/CT and PET/MRI Imaging of Vascular Inflammation 18F-FPPRGD2, Positron emission tomography, Computed tomography - Aortic Aneurysm, Abdominal, Carotid Atherosclerosis | Phase 2 | Withdrawn | Stanford University | 2019-10-01 | 2021-05-21 | |
| Strategy for Aortic Surgery Hemostasis TDM-621 - Ascending Aorta Abnormality, Ascending Aortic Dissection | Phase 2 / Phase 3 | Unknown | University of Sao Paulo General Hospital | 200 | 2018-12-04 | 2019-04-17 |
| Metformin Therapy in Non-diabetic AAA Patients Metformin Glucophage 500mg (IR) tablets M90, Placebo Oral Tablet - Abdominal Aortic Aneurysm | Phase 2 / Phase 3 | Unknown | Medical University of Vienna | 170 | 2018-09-26 | 2024-03-28 |
| Effect of Remote Ischemic Preconditioning on the Incidence of Contrast Induced Nephropathy in Patients Undergoing EVAR Remote ischemic preconditioning - Aortic Aneurysm, Ischemic Preconditioning | Phase 2 | Completed | Vascular Investigation Network Spanish Society for Angiology and Vascular Surgery | 120 | 2017-01-01 | 2022-04-28 |
| The Transfusion Triggers in Vascular Surgery Trial red blood cell transfusion - Atherosclerosis, Anemia | Phase 2 | Completed | Naestved Hospital | 58 | 2015-07-15 | 2017-07-25 |
| The Efficacy of Ticagrelor on Abdominal Aortic Aneurysm (AAA) Expansion Ticagrelor, Placebo - Abdominal Aortic Aneurysm | Phase 2 | Completed | Uppsala University | 145 | 2014-03-01 | 2018-05-02 |
| Cyclosporine A in Patients With Small Diameter Abdominal Aortic Aneurysms Cyclosporine A, Placebo - Abdominal Aortic Aneurysm,, Small Abdominal Aortic Aneurysm | Phase 2 | Unknown | Assistance Publique - Hôpitaux de Paris | 360 | 2013-12-01 | 2015-06-03 |
| ACZ885 for the Treatment of Abdominal Aortic Aneurysm ACZ885, Placebo - Abdominal Aortic Aneurysm (AAA) | Phase 2 | Terminated | Novartis Pharmaceuticals | 65 | 2013-12-01 | 2021-01-05 |
| Efficacy of Patient Centred Information for Vascular Disease Verbal and written information, Verbal and electronic information - Vascular Disease | Phase 2 | Completed | Mid Western Regional Hospital, Ireland | 50 | 2013-05-01 | 2014-03-26 |
| Evaluation of Predictors of Aortic Aneurysm Growth and Rupture Contrast Ultrasound - Abdominal Aortic Aneurysm | Phase 2 | Completed | Rabih A. Chaer | 66 | 2012-05-01 | 2023-11-13 |
| Curcumin to Prevent Complications After Elective Abdominal Aortic Aneurysm (AAA) Repair curcumin, placebo - Acute Kidney Injury, Abdominal Aortic Aneurysm | Phase 2 / Phase 3 | Completed | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 606 | 2011-11-01 | 2017-03-07 |
| AARDVARK (Aortic Aneurysmal Regression of Dilation: Value of ACE-Inhibition on RisK) perindopril arginine, amlodipine 5mgs, placebo - Abdominal Aortic Aneurysm | Phase 2 | Completed | Imperial College London | 224 | 2011-09-01 | 2021-01-26 |
| An Trial of Two Dosing Regimens of AP214 for the Prevention of Kidney Injury in Patients Undergoing Cardiac Surgery AP214, Placebo - Cardiac Surgery, Coronary Artery Bypass | Phase 2 | Completed | Action Pharma A/S | 77 | 2010-10-01 | 2012-03-15 |
| Magnetic Resonance Imaging of Aortic Aneurysm Instability Sinerem administration - Aortic Aneurysm | Phase 2 / Phase 3 | Completed | University of Edinburgh | 29 | 2008-11-01 | 2021-06-21 |
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Aortic Aneurysm, Abdominal (21) · Aortic Aneurysm, Thoracic (4) · Acute Kidney Injury (2) · Aneurysm (2) · Atherosclerosis (2) · Anemia (1) · Aneurysm, Ascending Aorta (1) · Aortic Aneurysm, Thoracoabdominal (1) · Arterial Occlusive Diseases (1) · Carotid Artery Diseases (1) · Carotid Stenosis (1) · Dissection, Ascending Aorta (1) · Hemorrhage (1) · Inflammation (1)
Aortic Diseases (33) · Cardiovascular Diseases (33) · Vascular Diseases (32) · Aneurysm (31) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Arteriosclerosis (2) · Central Nervous System Diseases (2) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Male Urogenital Diseases (2) · Nervous System Diseases (2) · Renal Insufficiency (2) · Urogenital Diseases (2)
Metformin (3) · Saline Solution (2) · Curcumin (1) · Cyclosporine (1) · Doxycycline (1) · Erythrocyte Transfusion (1) · FPP(RGD)2 (1) · Fibrinogen (1) · Ketamine (1) · Magnetic Resonance Imaging (1) · Melatonin (1) · Nicardipine (1) · Positron-Emission Tomography (1) · Sodium Chloride (1) · Spironolactone (1)
Stanford University (2) · W.L.Gore & Associates (2) · Action Pharma A/S (1) · Arizona Heart Institute (1) · Assistance Publique - Hôpitaux de Paris (1) · Boston Scientific Corporation (1) · CSL Behring (1) · Cordis US Corp. (1) · Duke University (1) · Duke Vascular, Inc. (1) · Eric Johnson (1) · Imperial College London (1) · Instituto de Investigación Hospital Universitario La Paz (1) · Leiden University Medical Center (1) · Lombard Medical (1)
United States (14) · Denmark (5) · United Kingdom (5) · Sweden (4) · Spain (3) · Germany (2) · Netherlands (2) · Australia (1) · Austria (1) · Brazil (1) · Canada (1) · Czechia (1) · France (1) · Ireland (1) · New Zealand (1)
Alan Lumsden, MD (1) · Alan Matsumoto, MD (1) · Alfio Carroccio, MD (1) · Amit X Garg, MD, PhD (1) · Anders Wanhainen, MD. PhD (1) · Andrew Brown, FRCS (1) · Andrew Thompson, FRCS (1) · Andy Shaw, M. D. (1) · Anna Rockich, Pharm D (1) · Anthony Lee, MD (1) · Barry Katzen, MD (1) · Carlos Vaquero (1)
PMID 20624109, PMID 21304070, PMID 23249928, PMID 23410777, PMID 25963302, PMID 30373740, PMID 30858230, PMID 31135888, PMID 34932836, PMID 36999821, PMID 38695613, PMID 41114449, PMID 41283274
R03AG042352 (1), R33HL146835 (1), R61HL146835 (1)