125 completed, 41 unknown, 19 withdrawn, 17 recruiting. 94 Not applicable, 70 Phase 2, 38 Phase 1, 28 Phase 3, 12 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Curcumin Extract Added to Ciprofloxacin for Typhoid Carriers Among Food Handlers of the Free Nutritious Meal Program Curcumin extract, Ciprofloxacin, Placebo - Typhoid Carrier, Typhoid Fever | Phase 2 | Not yet recruiting | Universitas Sebelas Maret | 100 | 2026-11-02 | 2026-10-30 |
| Curcumin Versus Ibuprofen for Exercise-Induced Muscle Damage in Physically Active Women Curcumin, Ibuprofen, Placebo - Exercise-Induced Muscle Damage, Delayed Onset Muscle Soreness (DOMS) | Not applicable | Completed | University of Valladolid | 36 | 2026-08-22 | 2026-09-23 |
| Plant-derived Nutrients in the Prevention and Prognosis of Breast Cancer in Women. Curcumin - Breast Cancer | Not applicable | Active not recruiting | Keda Yu | 639 | 2026-08-01 | 2026-10-09 |
| Cognitive Effects of Bioavailable Curcumin Curcumin, Placebo - Memory, Cognitive Function Decline | Phase 2 | Withdrawn | University of California, Los Angeles | 2026-04-01 | 2026-05-01 | |
| Curcumin in Critically Ill Patients With Sepsis Curcumin, Placebo - Sepsis | Not applicable | Recruiting | Hospital Civil de Guadalajara | 56 | 2026-03-01 | 2026-09-17 |
| Evaluation of the Pharmacokinetics of Curcumin Capsules in Healthy Human Curcumin, Nanocurcumin - Healthy | Not applicable | Not yet recruiting | Kingdomway (Inner Mongolia) Nutritional Food Co., Ltd. | 12 | 2026-01-28 | 2026-01-30 |
| A Phase II Single-Arm Study of High-Bioavailability Curcumin as Neoadjuvant Chemoradiotherapy in Mid-to-Low Rectal Cancer: Integrated Clinical and Translational Analysis of Tumor Tissue Curcumin (BCM-95®) - Rectal Cancer, Locally Advanced Rectal Cancer | Phase 2 | Not yet recruiting | Chang Gung Memorial Hospital | 72 | 2026-01-01 | 2025-11-25 |
| Effect of Curcumin Add-On Therapy on Quality of Life and IL-1β Levels in Patients With Schizophrenia Curcumin, Risperidone 4mg/day - Schizophrenia, Psychotic Disorders | Not applicable | Completed | Rinvil Renaldi | 44 | 2025-11-01 | 2026-04-14 |
| Curcumin Plus Topical Steroid Versus Topical Steroid Alone for Oral Submucous Fibrosis Curcumin and and triamcinolone acetonide, Triamcinolone Acetonide - Oral Submucous Fibrosis | Not applicable | Completed | Liaquat College of Medicine and Dentistry | 60 | 2025-10-10 | 2026-10-23 |
| Pilot Assessment of the Safety of a Combination of Curcumin, Omega-3, and Vitamin D Supplements in ACPA+ Individuals curcumin, omega-3, and vitamin D (COD) - Healthy Participants | Not applicable | Not yet recruiting | University of Manitoba | 50 | 2025-10-01 | 2025-08-01 |
| Single Oral Dose Comparative Bioavailability Study of Investigational Product in Healthy Human Subjects Under Fasting Conditions. Curcumin Dispersome formulation, Non-formulated Curcumin, Benchmark Formulation 1 - Turmipure Gold™ - Healthy Volunteer | Not applicable | Completed | Vedic Lifesciences Pvt. Ltd. | 24 | 2025-09-15 | 2026-10-05 |
| CurQD as Add-On Therapy in Vedolizumab-Treated Ulcerative Colitis Patients: Retrospective Cohort Study CurQD (Curcumin + QingDai combination) - Ulcerative Colitis (UC) | Active not recruiting | Evinature Ltd. | 400 | 2025-09-07 | 2025-11-20 | |
| Curcumin & Astaxanthin for Lowering Triglyceride Readings and Inflammation Curcumin (Longvida™), Half Dose Curcumin (Longvida™), Astaxanthin - Triglycerides | Not applicable | Recruiting | Medinutra LLC | 64 | 2025-07-18 | 2026-07-14 |
| Snakehead Fish Extract and Curcumin Co-Supplementation in Advanced Lung Cancer on Inflammation, Nutritional Status, and Quality of Life Snakehead Fish Extract and Curcumin - Lung Cancer (NSCLC) | Not applicable | Completed | Universitas Sumatera Utara | 60 | 2025-07-01 | 2026-10-30 |
| The Therapeutic Effect of Curcumin in Nanogels Compared to 0.1% FAO in the Management of Oral Lichen Planus Curcumin in Nanogels, 0.1% Fluocinolone Acetonide Oral Paste - Oral Lichen Planus | Not applicable | Recruiting | Chulalongkorn University | 30 | 2025-06-01 | 2026-03-06 |
| Concomitant Curcumin Palliative Radiotherapy in Advanced Cervical Cancer Trial Curcumin, Palliative radiotherapy - Cervical Cancer | Not applicable | Recruiting | Addis Ababa University | 27 | 2025-04-10 | 2025-04-20 |
| Comparison of Curcumin and Intralesional Steroids in Oral Submucous Fibrosis Curcumin (Turmeric), Intralesional Steroid Injection - Oral Submucous Fibrosis | Phase 3 | Not yet recruiting | Services Institute of Medical Sciences, Pakistan | 70 | 2025-04-01 | 2025-03-06 |
| Safety of Anal Curcumin Curcuminoid Capsules - Anal High Grade Squamous Intraepithelial Lesion | Phase 1 | Recruiting | Lisa Flowers | 48 | 2025-03-17 | 2026-08-18 |
| The Effect of Curcumin on Inflammatory Markers in Hemodialysis Patients Curcumin (Longvida™), Placebo - Hemodialysis | Phase 2 | Not yet recruiting | University of Guadalajara | 70 | 2025-03-15 | 2025-02-17 |
| Antimicrobial Effect of Curcumin Versus Chlorohexidine on Oral Microbiome Curcumin, Chlorohexidine - Dental Caries, Dental Plaque Index | Not applicable | Not yet recruiting | Cairo University | 54 | 2025-03-01 | 2025-02-26 |
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Inflammation (15) · Breast Neoplasms (11) · Colonic Neoplasms (9) · Diabetes Mellitus, Type 2 (9) · Prostatic Neoplasms (8) · Renal Insufficiency, Chronic (8) · Cognitive Dysfunction (7) · Colorectal Neoplasms (6) · Diabetes Mellitus (5) · Irritable Bowel Syndrome (5) · Motor Activity (5) · Neoplasms (5) · Colitis, Ulcerative (4) · Depression (4) · Insulin Resistance (4)
Ain Shams University (7) · M.D. Anderson Cancer Center (7) · National Nutrition and Food Technology Institute (4) · National Cancer Institute (NCI) (3) · Shahid Beheshti University of Medical Sciences (3) · University of Alabama at Birmingham (3) · University of California, Los Angeles (3) · University of Rochester (3) · Baylor Research Institute (2) · Cairo University (2) · Centre Jean Perrin (2) · Chinese University of Hong Kong (2) · Coordinación de Investigación en Salud, Mexico (2) · Fateme Moshirenia (2) · Hadassah Medical Organization (2)
United States (84) · Iran (11) · Canada (10) · Egypt (10) · Israel (10) · Mexico (8) · Brazil (6) · India (6) · Indonesia (6) · Thailand (6) · China (5) · United Kingdom (5) · France (4) · Pakistan (4) · Italy (3)
Fernando Guerrero, PhD (2) · Jan Frank, Ph.D. (2) · Michael A Liss, MD (2) · Paul A Knepper, MD, PhD (2) · Raja K Sivamani, M.D. (2) · Somlak Chuengsamarn, Medical Doctor (2) · Urvi A Shah, MD, MS (2) · Vladimir Lerner, MD, PhD (2) · Yair Lotan, MD (2) · Abolfazl Razzaghdoust (1) · Ahmed Y Gamal, Professor (1) · Alice P Pentland, MD (1) · Alon Lang, MD (1) · Aminah Jatoi, M.D. (1) · Amit Assa, MD (1)
PMID 18628464, PMID 22773702, PMID 24445038, PMID 29802852, PMID 37916745, PMID 10051376, PMID 10444409, PMID 10480510, PMID 10857969, PMID 10990036, PMID 11323096, PMID 11376301, PMID 11712783, PMID 12359244, PMID 12676044, PMID 1291482, PMID 1574446, PMID 1578097, PMID 15793117, PMID 16371925, PMID 16545122, PMID 17181736, PMID 17509812, PMID 17569205, PMID 17604143, PMID 17942826, PMID 17951067, PMID 18204357, PMID 18252805, PMID 18611924, PMID 19393114, PMID 19594223, PMID 19660572, PMID 19735878, PMID 20046768, PMID 20160040, PMID 20354091, PMID 20395228, PMID 20561944, PMID 20580421, PMID 20726007, PMID 21296615, PMID 21382138, PMID 21532153, PMID 21565893, PMID 21788628, PMID 21810420, PMID 21921569, PMID 22024084, PMID 22144828
UG1CA189823 (2), 1UL1RR025014-01 (1), 2014 (1), 2016 (1), 5KL2RR024136-03 (1), N01CN00042 (1), N01CN35160 (1), P30AG028740 (1), P30CA006973 (1), P30CA014089 (1), P30CA015083 (1), P30CA016056 (1), P30CA022453 (1), P30CA046592 (1), P30CA062203 (1)