25 completed, 6 terminated, 6 unknown, 4 not yet recruiting. 13 Not applicable, 11 Phase 4, 9 Phase 3, 4 Phase 2, 3 Phase 1.
Follow Nicardipine: new trials by email Literature Review of Nicardipine trials Research Report on Nicardipine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lumbar Drain With Intrathecal Nicardipine in Aneurysmal Subarachnoid Hemorrhage Normal Saline, Nicardipine - Subarachnoid Hemorrhage | Phase 4 | Not yet recruiting | Wake Forest University Health Sciences | 214 | 2027-01-01 | 2026-10-01 |
| EIT Evaluation of Different Antihypertensive Agents on the Ventilation-Perfusion Ratio in Patients With Acute Respiratory Failure Nitroglycerin, Nicardipine - Acute Respiratory Failure (ARF), Hypertension | Not applicable | Not yet recruiting | First Affiliated Hospital of Wannan Medical College | 12 | 2026-07-15 | 2026-07-02 |
| Remifentanil Monotherapy vs. Remifentanil-Nicardipine for Controlled Hypotension in Otolaryngological Surgery Remifentanil / Nicardipine, Remifentanil - Otolaryngological Surgery, Anesthesia | Not applicable | Not yet recruiting | Dicle University | 60 | 2026-06-30 | 2026-06-22 |
| Remifentanil vs. Nicardipine for Controlled Hypotension in Elective Nasal Surgery Nicardipine, Remifentanil - Nasal Surgery, Anesthesia | Not applicable | Not yet recruiting | Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital | 44 | 2026-06-25 | 2026-06-22 |
| Prevention of Coronary Microvascular Dysfunction Post-PCI by Intracoronary Nicardipine Nicardipine, Sterile Saline - Coronary Artery Disease | Early Phase 1 | Withdrawn | Thomas Jefferson University | 2025-12-01 | 2024-04-26 | |
| A Comparison of Nicardipine and Labetalol for Blood Pressure Control in Intensive Care Patients After Hemorrhagic Stroke Brain Surgery Nicardipine, Labetalol - Hemorrhagic Strokes, Postoperative Hypertension | Not applicable | Completed | Universitas Sumatera Utara | 30 | 2025-11-14 | 2026-01-23 |
| NICardipine for Fast Achievement of Systolic BP Targets in ICH Nicardipine, Glyceryl trinitrate - Intracerebral Haemorrhage | Phase 4 | Recruiting | Aarhus University Hospital | 88 | 2025-10-01 | 2026-06-24 |
| Hypotensive Anesthesia for Orthognathic Surgery Dexmedetomidine, Nicardipine, Labetalol - Hypotensive Anesthesia, Orthognathic Surgery | Phase 4 | Completed | Boston Medical Center | 90 | 2025-03-04 | 2026-03-31 |
| Outcome in Patients Treated With Endovascular Thrombectomy - optIMAL Blood Pressure Control 2 (OPTIMAL-BP 2) BP lowering drugs (nicardipine, labetalol, urapidil), BP raising drug (phenylephrine) or BP lowering drugs (nicardipine, labetalol, urapidil) - Acute Ischemic Stroke | Phase 3 | Recruiting | Yonsei University | 176 | 2024-10-01 | 2026-02-13 |
| The Contractile Response of the Thoracic Aorta to Vasoactive Substances Phenylephrine - Human Thoracic Aorta Contractility | Completed | Catharina Ziekenhuis Eindhoven | 70 | 2024-05-27 | 2025-02-18 | |
| Comparison of the Effects of Nicardipine and Remifentanil on Surgical Visual Field Nicardipine, Remifentanil - Other Complications of Surgical and Medical Procedures | Not applicable | Unknown | Erol Karaaslan | 64 | 2023-11-30 | 2023-11-28 |
| Effects of Subcutaneously Infiltrated Nicardipine on the Success Rate of Radial Artety Cannulation Nicardipine, Normal saline - Radial Artery Cannulation | Not applicable | Unknown | Mahidol University | 190 | 2023-03-13 | 2023-06-27 |
| Dilution of Verapamil During Intraarterial Administration Verapamil, Nicardipine - Vasospasm;Peripheral, Burning | Early Phase 1 | Completed | University of Illinois at Chicago | 55 | 2022-12-13 | 2024-11-27 |
| Relationship Between Perioperative Carotid Blood Flow Monitoring and Cerebral Function Protection in Cardiac Surgery Nicardipine, normal saline - Coronary Artery Bypass Grafting, Cardiopulmonary Bypass | Not applicable | Completed | Nanjing First Hospital, Nanjing Medical University | 64 | 2022-04-22 | 2022-10-19 |
| Nicardipine to Avoid Spasm in Trans Radial Percutaneous Coronary Intervention Nicardipine - Spasm Artery | Phase 3 | Completed | Pr. Semir Nouira | 1500 | 2020-11-01 | 2022-02-08 |
| Outcome in Patients Treated with Intraarterial Thrombectomy - OptiMAL Blood Pressure Control (OPTIMAL-BP) conventional blood pressure control (labetalol, nicardipine), intensive blood pressure control (labetalol, nicardipine) - Ischemic Stroke | Phase 4 | Completed | Yonsei University | 306 | 2020-06-18 | 2025-03-19 |
| Coronavirus (COVID-19) ACEi/ARB Investigation Thiazide or Thiazide-like diuretics, Calcium Channel Blockers, ACE inhibitor - Hypertension, COVID-19 | Phase 4 | Suspended | National University of Ireland, Galway, Ireland | 2414 | 2020-04-30 | 2020-06-30 |
| A Safety and Efficacy Study of NicaPlant® in Aneurysmal Subarachnoid Haemorrhage Patients Undergoing Aneurysm Clipping Nicardipine, Standard of care - Aneurysmal Subarachnoid Hemorrhage | Phase 2 | Completed | BIT Pharma GmbH | 41 | 2020-04-05 | 2023-07-12 |
| Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care: - Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension | Recruiting | Duke University | 5000 | 2020-03-05 | 2026-08-21 | |
| ACEI or ARB and COVID-19 Severity and Mortality in US Veterans ACEI/ARB, Non-ACEI/ARB, ACEI - Hypertension, COVID | Completed | University of Utah | 22213 | 2020-01-19 | 2021-04-28 |
Showing 20 of 46. Sign in to see all of them.
Hypertension (14) · Cerebral Hemorrhage (7) · Subarachnoid Hemorrhage (5) · Ischemic Stroke (4) · Stroke (4) · COVID-19 (2) · Cardiovascular Diseases (2) · Coronary Artery Disease (2) · Coronavirus Infections (2) · Heart Failure (2) · Hemorrhage (2) · Pain (2) · Vasospasm, Intracranial (2) · Acute Coronary Syndrome (1) · Adrenal Insufficiency (1)
Yonsei University (4) · The George Institute (3) · Duke University (2) · The Medicines Company (2) · University Hospital, Strasbourg, France (2) · University of Illinois at Chicago (2) · University of Minnesota (2) · Aarhus University Hospital (1) · Astellas Pharma China, Inc. (1) · BIT Pharma GmbH (1) · Boston Medical Center (1) · Cambridge University Hospitals NHS Foundation Trust (1) · Catharina Ziekenhuis Eindhoven (1) · Central Hospital, Nancy, France (1) · Chinese PLA General Hospital (1)
United States (19) · China (8) · France (5) · Germany (4) · South Korea (4) · Australia (3) · Austria (2) · Canada (2) · Indonesia (2) · United Kingdom (2) · Argentina (1) · Belgium (1) · Brazil (1) · Chile (1) · Denmark (1)
Craig Anderson, PhD (2) · W. Frank Peacock, MD (2) · Adam P Bress, PharmD, MS (1) · Adnan I Qureshi, MD (1) · Adnan I. Qureshi, MD (1) · Andy Shaw, M. D. (1) · Ben Z Roitberg, MD (1) · Bruce Neal, PhD (1) · Chi Hornik (1) · Chul Ho Chang, MD, PhD (1) · Craig S Anderson, MD (1) · David Wang, DO (1) · Erol Karaaslan, assoc prof (1)
PMID 32640944, PMID 41855454, PMID 42848972, PMID 25503550, PMID 25589782, PMID 25657175, PMID 25712944, PMID 25823544, PMID 26746184, PMID 27165954, PMID 27178897, PMID 27919055, PMID 30418098, PMID 30890109, PMID 31085948, PMID 33598552, PMID 38018833, PMID 40541207, PMID 18396107, PMID 18606927, PMID 18806012, PMID 19770736, PMID 20457956, PMID 20823381, PMID 21626077, PMID 21707983, PMID 22129475, PMID 22364823, PMID 22560810, PMID 22678090, PMID 22744655, PMID 22989898, PMID 23230457, PMID 23233387, PMID 23535700, PMID 23647568, PMID 23713578, PMID 24149007, PMID 24261345, PMID 24530176, PMID 25141250, PMID 25179153, PMID 25497513, PMID 25677598, PMID 25801872, PMID 26044442, PMID 26148170, PMID 26202097, PMID 26265125, PMID 26810526
2017 (1), K23NS113858 (1), R01NS044976 (1), U01NS056975 (1), U01NS059041 (1), U01NS061861 (1), U01NS062091 (1)