7 completed, 6 unknown, 2 recruiting, 2 terminated. 17 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 17 | Completed 7, Unknown 6, Recruiting 2, Terminated 2 |
| Phase 2 | 2 | Completed 1, Recruiting 1 |
Follow Aortic Aneurysm: new trials by email Literature Review of Aortic Aneurysm trials Research Report on Aortic Aneurysm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| HEART: Pilot Randomized Controlled Trial Spironolactone, Placebo - Thoracic Aortic Aneurysm | Phase 1 / Phase 2 | Recruiting | Mayo Clinic | 50 | 2026-05-25 | 2026-06-08 |
| Nicotinamide Riboside (NR) to Treat Moyamoya-like Cerebrovascular Disease in Smooth Muscle Dysfunction Syndrome (SMDS) Nicotinamide riboside (NR) - Smooth Muscle Dysfunction Syndrome (SMDS) | Phase 1 | Recruiting | The University of Texas Health Science Center, Houston | 15 | 2024-03-06 | 2025-09-12 |
| Comparison of Carbon Dioxide and Saline Flush to Saline Flush in TEVAR and TAVI Procedures to Reduce Cerebral Ischemia Carbon Dioxide and Saline Flush, Standard Saline Flush - Thoracic Aortic Aneurysm, Aortic Stenosis Symptomatic | Phase 1 | Unknown | University Health Network, Toronto | 20 | 2019-07-20 | 2020-09-23 |
| Detection of Hypoxia in Human Thoracic Aorta Using Pimonidazole Hydrochloride Pimonidazole hydrochloride - Aortic Aneurysm, Thoracic | Phase 1 | Completed | Thomas Gleason | 9 | 2018-09-01 | 2026-01-23 |
| Safety and Efficacy of Allogeneic MSCs in Promoting T-regulatory Cells in Patients With Small Abdominal Aortic Aneurysms 1 million MSCs/kg, 3 million MSCs/kg, Placebo - Abdominal Aortic Aneurysm | Phase 1 | Terminated | VA Office of Research and Development | 28 | 2016-12-05 | 2024-08-09 |
| Intraoperative Nasal Insulin Effect on Plasma and CSF Insulin Concentration and Blood Glucose Humulin R, Normal Saline - Ischemic Heart Disease, Aortic Aneurysm | Phase 1 | Unknown | Hiroaki Sato, MD., PhD. | 141 | 2016-09-01 | 2021-02-24 |
| Evaluation of a New Imagingtechnologie for Thrombosis [18F]-GP1 - Abdominal Aortic Aneurysm, Deep Vein Thrombosis | Phase 1 | Terminated | University of Zurich | 4 | 2014-09-01 | 2017-05-09 |
| Image Fusion of Preprocedural CTA With Real Time Fluoroscopy to Enhance EVAR Repair Using pre-procedural CTA to guide advanced EVAR procedure - Abdominal Aortic Aneurysm (AAA) | Phase 1 | Unknown | University Health Network, Toronto | 20 | 2014-02-01 | 2014-11-20 |
| Treovance Stent-Graft With Navitel Delivery System for Patients With Infrarenal Abdominal Aortic Aneurysms Treovance Abdominal Aortic Stent-Graft with Navitel Delivery System - Abdominal Aortic Aneurysms | Phase 1 | Completed | Bolton Medical | 30 | 2011-06-01 | 2017-12-20 |
| The Altura Abdominal Aortic Aneurysm (AAA) Endograft Safety and Feasibility Study Altura Medical Abdominal Aortic Aneurysm Stent-Graft - Abdominal Aortic Aneurysms | Phase 1 | Unknown | Altura Medical Inc. | 50 | 2011-04-01 | 2015-01-15 |
| Preventing Myocardial Ischemia by Preconditioning in Elective Operation for Abdominal Aortic Aneurysm preconditioning, Normal surgery, with sham intervention without inflating arm cuff - Aortic Aneurysm | Phase 1 | Unknown | Aarhus University Hospital | 200 | 2011-01-01 | 2015-01-14 |
| ENTRUST - TAArget® Thoracic Stent Graft Clinical Trial Endovascular repair of TAA in the descending Thoracic Aorta - Thoracic Aortic Aneurysm | Phase 1 | Unknown | Duke Vascular, Inc. | 30 | 2010-01-01 | 2015-05-20 |
| South American Abdominal Stent Graft Trial Ovation Abdominal Stent Graft System - Abdominal Aortic Aneurysm | Phase 1 | Completed | TriVascular, Inc. | 20 | 2009-11-01 | 2021-06-04 |
| Comparing Fluoroscopy and Technological Methods for Guidance During Endovascular Procedures Technological Methods, Regular Fluoroscopy - Aortic Aneurysm, Abdominal | Phase 1 | Completed | Norwegian University of Science and Technology | 17 | 2007-08-01 | 2013-04-29 |
| Exercise Therapy to Treat Adults With Abdominal Aortic Aneurysms Exercise Program - Aortic Aneurysm, Abdominal | Phase 1 | Completed | Stanford University | 2400 | 2006-11-01 | 2013-06-07 |
| A Phase I Evaluation of the Safety of the TriVascular Stent-Graft System in the Treatment of Abdominal Aortic Aneurysms TriVascular Stent-Graft System - Abdominal Aortic Aneurysm | Phase 1 | Completed | Boston Scientific Corporation | 43 | 2003-02-01 | 2011-01-28 |
| Cordis Bilateral AAA Device Compared to Open Surgical Repair of Abdominal Aortic Aneurysms (ARIBA) Cordis AAA Bilateral Device - Abdominal Aortic Aneurysm | Phase 1 / Phase 2 | Completed | Cordis US Corp. | 29 | 1999-12-01 | 2005-12-09 |
Aortic Aneurysm, Abdominal (10) · Aortic Aneurysm, Thoracic (5) · Aneurysm (3) · Stroke (2) · Cerebrovascular Disorders (1) · Hypoxia (1) · Myocardial Ischemia (1) · Venous Thrombosis (1)
Aortic Diseases (17) · Cardiovascular Diseases (17) · Vascular Diseases (17) · Aneurysm (14) · Brain Diseases (2) · Central Nervous System Diseases (2) · Nervous System Diseases (2) · Cerebrovascular Disorders (1) · Embolism and Thrombosis (1) · Heart Diseases (1) · Pathological Conditions, Signs and Symptoms (1) · Signs and Symptoms (1) · Signs and Symptoms, Respiratory (1) · Thrombosis (1)
Carbon Dioxide (1) · Insulin (1) · Plasmalyte A (1) · Resistance Training (1) · Saline Solution (1) · Spironolactone (1) · nicotinamide-beta-riboside (1)
University Health Network, Toronto (2) · Aarhus University Hospital (1) · Altura Medical Inc. (1) · Bolton Medical (1) · Boston Scientific Corporation (1) · Cordis US Corp. (1) · Duke Vascular, Inc. (1) · Hiroaki Sato, MD., PhD. (1) · Mayo Clinic (1) · Norwegian University of Science and Technology (1) · Stanford University (1) · The University of Texas Health Science Center, Houston (1) · Thomas Gleason (1) · TriVascular, Inc. (1) · University of Zurich (1)
United States (9) · Canada (3) · Chile (2) · Denmark (1) · Latvia (1) · Norway (1) · Switzerland (1)
Albrecht Kramer, MD (1) · Dianna Milewicz, MD, PhD (1) · Francisco Valdes, MD (1) · Frode Manstad-Hulaas, MD (1) · Kartikeshwar Kasirajan, M.D. (1) · Kong Teng Tan, MD (1) · Kong Teng Tan, MD, FRCPC (1) · Michael Marin, MD (1) · Michael P Murphy, MD BS (1) · Pamela Grady, PhD (1) · Petter Aadahl, Professor (1) · Philipp A Kaufmann, Prof (1) · Ronald L. Dalman, MD (1) · Thais Coutinho (1) · Thomas G Gleason, MD (1)
PMID 20137879, PMID 22313205, PMID 23416349, PMID 23793234, PMID 23978572, PMID 24763187, PMID 25204854, PMID 28382529, PMID 30895515, PMID 33721199, PMID 36645250
P50HL083800 (1)