70 completed, 44 recruiting, 26 unknown, 19 active not recruiting. 75 Not applicable, 8 Phase 4, 5 Phase 1, 5 Phase 2, 5 Phase 3.
Follow Aortic Aneurysm, Thoracic: new trials by email Literature Review of Aortic Aneurysm, Thoracic trials Research Report on Aortic Aneurysm, Thoracic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Remimazolam on Postoperative Cognitive Dysfunction and Neuroinflammatory Biomarkers in Patients Undergoing Aortic Arch Surgery Remimazolam Besylate, propofol - Aortic Aneurysm of the Proximal Arch, Aortic Aneurysms Arch | Phase 4 | Not yet recruiting | Seoul National University Hospital | 80 | 2026-10-01 | 2026-09-17 |
| Selective Antegrade Cerebral Perfusion and Perioperative Optic Nerve Sheath Diameter in Ascending Aortic Surgery Optic nerve sheath and optic nerve diameter ultrasonography, Transcranial Doppler ultrasonography - Aortic Diseases, Cardiac Surgical Procedures | Not applicable | Not yet recruiting | Koşuyolu Kartal Heart Training and Research Hospital | 134 | 2026-09-30 | 2026-09-02 |
| MBA Early Feasibility Study GORE® Multibranch Arch Endoprosthesis, GORE® Ascending Stent Graft - Thoracic Aortic Aneurysm, Penetrating Aortic Ulcers (PAUs) | Not applicable | Recruiting | W.L.Gore & Associates | 20 | 2026-09-02 | 2026-10-01 |
| A Study of Lipid Metabolism and Mitochondrial Function in Myeloid Cells and Total Aortic Tissue in Patients With Ascending Thoracic Aortic Aneurysm (ATA) and Bicuspid (BA) or Tricuspid (TA) Aortic Valves. Additional blood samples, Collection of discarded ascending aortic tissue - Ascending Aortic Aneurysm | Recruiting | Centre Hospitalier Universitaire Dijon | 50 | 2026-06-28 | 2026-07-13 | |
| Fibroblast Line Evaluation for COL5A eXpression and Thoracic Aortic Aneurysms: in Vitro Characterization of Cutaneous Fibroblasts in Adult Patients Mutations Affecting the COL5A Gene, Aneurysm Aortic | Recruiting | IRCCS Policlinico S. Donato | 20 | 2026-06-24 | 2026-07-02 | |
| HEART: Pilot Randomized Controlled Trial Spironolactone, Placebo - Thoracic Aortic Aneurysm | Phase 1 / Phase 2 | Recruiting | Mayo Clinic | 50 | 2026-05-25 | 2026-06-08 |
| GORE® TAG® Thoracic Branch Endoprosthesis Zone 0/1 Post-Approval Study GORE® TAG® Thoracic Branch Endoprosthesis - Aortic Arch Dissection, Aortic Arch Aneurysm | Not applicable | Recruiting | W.L.Gore & Associates | 125 | 2026-03-02 | 2026-10-23 |
| TBE Zone 2 PMS in Japan Gore® TAG® Thoracic Aortic Branch Stent Graft System - Aneurysm Thoracic, Dissection of Aorta, Thoracic | Recruiting | W.L.Gore & Associates | 200 | 2025-12-15 | 2026-02-05 | |
| Clinical Study to Evaluate the Safety and Effectiveness of Arcevo LSA Arcevo™ LSA Hybrid Stent Graft System - Aortic Arch Aneurysm, Aortic Arch Dissection | Not applicable | Recruiting | Artivion Inc. | 132 | 2025-11-04 | 2026-10-15 |
| Triple Branched Stent Graft System for Aortic Arch Lesions Treated with the triple branched stent graft system - Aortic Arch Aneurysm, Aortic Arch Pseudoaneurysm | Not applicable | Recruiting | Changhai Hospital | 96 | 2025-11-03 | 2026-10-22 |
| Strength Tracking From Wall Tichness Over Aortic Biomechanics (STORM) Aneurysm Aortic, Aneurysm Aortic Root | Recruiting | IRCCS Policlinico S. Donato | 40 | 2025-10-25 | 2026-03-11 | |
| European Multi-Centre Post-Market Registry on Thoracic Endovascular Arch Repair Using Castor™ and Cratos™ Implantation with Castor™ stent graft, Implantation with Cratos™ stent graft - Dissection of Thoracic Aorta, Dissection of Thoracic Descending Aorta | Recruiting | Shanghai MicroPort Endovascular MedTech（Group）Co., Ltd | 100 | 2025-09-12 | 2026-06-25 | |
| Impact of Right Atrial Occlusion on TEVAR Outcomes Right atrial balloon occlusion, Non right atrial balloon occlusion - Thoracic Aortic Aneurysm, Thoracic Aortic Dissection | Not yet recruiting | University of Calgary | 100 | 2025-09-01 | 2025-06-29 | |
| Prophylactic Suture Line Sealing With NE'X Glue R-eco in Cardiac and Vascular Surgery Surgical placement of a prosthetic or biologic graft (patch), or an allograft for cardiac and (cardio)vascular repair. - Aortic Aneurysm, Aortic Aneurysm Abdominal | Not applicable | Not yet recruiting | Grena Biomed Limited | 60 | 2025-06-30 | 2025-04-09 |
| Long-term Characterization of GORE® TAG® Conformable Thoracic Stent Graft With ACTIVE CONTROL System Performance Endovascular - Vascular Disease, Dissection | Recruiting | W.L.Gore & Associates | 1500 | 2025-06-19 | 2026-08-19 | |
| Fibroblasts and Thoracic Aortic Aneurysms: in Vitro Characterization in With Marfan Syndrome and Genetic Aortic Diseases Rare Diseases, Thoracic Aortic Aneurysm (TAA) | Enrolling by invitation | IRCCS Policlinico S. Donato | 15 | 2025-06-17 | 2026-05-28 | |
| Effects of Exercise on Thoracic Aneurysms Exercise group - Thoracic Aortic Aneurysm | Not applicable | Recruiting | Laval University | 30 | 2025-06-10 | 2025-06-29 |
| Genetic Aortic Diseases and Cardiovascular Complications. An Observational Survey of Risk Factors. Journey to diagnosis, Quality of life, functional health and well-being, Awareness and self-esteem, acceptance of the condition - Thoracic Aortic Aneurysm (TAA) | Recruiting | IRCCS Policlinico S. Donato | 208 | 2025-05-06 | 2026-02-05 | |
| POCUS Screening for TAA in Hypertensive Patients in the ED Point-of-care ultrasound - Thoracic Aortic Aneurysm (TAA), Aortic Dissection | Completed | Chinese University of Hong Kong | 1483 | 2025-04-22 | 2026-10-21 | |
| Post Market Registry for GORE® TAG® Thoracic Branch Endoprosthesis GORE® TAG® Thoracic Branch Endoprosthesis - Aneurysm, Dissection, Aortic | Active not recruiting | W.L.Gore & Associates | 155 | 2025-02-20 | 2026-07-30 |
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Aortic Aneurysm (34) · Aortic Dissection (32) · Aneurysm, Aortic Arch (27) · Aneurysm, Ascending Aorta (21) · Aneurysm (19) · Aortic Aneurysm, Abdominal (19) · Dissection, Thoracic Aorta (19) · Aortic Diseases (16) · Penetrating Atherosclerotic Ulcer (15) · Aortic Aneurysm, Thoracoabdominal (12) · Bicuspid Aortic Valve Disease (10) · Aortic Root Aneurysm (8) · Aortic Valve Insufficiency (7) · Aortic Valve Stenosis (7)
Cardiovascular Diseases (180) · Vascular Diseases (179) · Aortic Diseases (167) · Aneurysm (164) · Aortic Aneurysm (149) · Acute Aortic Syndrome (59) · Dissection, Blood Vessel (52) · Heart Diseases (26) · Arterial Occlusive Diseases (21) · Pathological Conditions, Signs and Symptoms (21) · Aortic Dissection (20) · Arteriosclerosis (20) · Heart Valve Diseases (17) · Pathologic Processes (17)
Endovascular Aneurysm Repair (13) · Surgical Procedures, Operative (3) · Losartan (2) · Propofol (2) · Transcatheter Aortic Valve Replacement (2) · Ultrasonography, Doppler, Transcranial (2) · Acetazolamide (1) · Blood Specimen Collection (1) · Carbon Dioxide (1) · Cardiac Surgical Procedures (1) · Computed Tomography Angiography (1) · Conversion to Open Surgery (1) · Drug Delivery Systems (1) · Epigenesis, Genetic (1) · Gelatin Sponge, Absorbable (1)
W.L.Gore & Associates (15) · Medtronic Cardiovascular (11) · IRCCS Policlinico S. Donato (7) · Vascutek Ltd. (6) · Bolton Medical (5) · IRCCS San Raffaele (5) · Assistance Publique - Hôpitaux de Paris (3) · Centre Hospitalier Universitaire de Saint Etienne (3) · Cook Research Incorporated (3) · Endospan Ltd. (3) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (3) · Tomsk National Research Medical Center of the Russian Academy of Sciences (3) · University of Michigan (3) · Changhai Hospital (2) · China National Center for Cardiovascular Diseases (2)
United States (64) · Italy (39) · France (27) · Germany (22) · Netherlands (17) · United Kingdom (17) · China (13) · Spain (11) · Canada (10) · Russia (9) · Belgium (8) · Denmark (8) · Sweden (8) · Switzerland (7) · Turkey (Türkiye) (5)
Adam W Beck, MD (2) · Boris N. Kozlov, MD, PhD (2) · Eric Roselli, MD (2) · Himanshu Patel, MD (2) · Mark Farber, MD (2) · Michael D Dake, MD (2) · Ronald Fairman, MD (2) · Venkatesh Ramaiah, MD (2) · Wilson Szeto, MD (2) · Alan Lumsden, MD (1) · Alan Matsumoto, MD (1) · Alberto C Figueroa, PhD (1) · Alessandro Pini (1) · Alexander J Fletcher, MD (1) · Alexander Oberhuber (1)
PMID 37059239, PMID 37330702, PMID 38989575, PMID 39963789, PMID 21917992, PMID 31126765, PMID 33892122, PMID 34297930, PMID 38695613, PMID 42729155, PMID 12683565, PMID 16500110, PMID 20137879, PMID 20619242, PMID 21616506, PMID 22545887, PMID 23384495, PMID 23410783, PMID 23809203, PMID 23867913, PMID 24502488, PMID 24636714, PMID 24685375, PMID 25088739, PMID 25240525, PMID 25284629, PMID 25439771, PMID 25595400, PMID 25735260, PMID 25809354, PMID 25935877, PMID 26052700, PMID 26069087, PMID 26356765, PMID 26372191, PMID 26409997, PMID 26483004, PMID 26637837, PMID 27109801, PMID 27237404, PMID 27280802, PMID 27565586, PMID 27856475, PMID 27866781, PMID 27986479, PMID 28216359, PMID 28366302, PMID 28596039, PMID 28601820, PMID 29248241
2009 (1), 2023 (1), 5KL2RR025006 (1), UL1TR001082 (1)