18 completed, 6 unknown, 2 terminated, 1 recruiting. 28 Phase 2, 6 Phase 3, 5 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 28 | Completed 18, Unknown 6, Terminated 2, Recruiting 1, Withdrawn 1 |
| Phase 3 | 6 | Completed 3, Unknown 2, Recruiting 1 |
| Phase 1 | 5 | Completed 2, Terminated 1, Unknown 1, Withdrawn 1 |
Follow Acute Stroke: new trials by email Literature Review of Acute Stroke trials Research Report on Acute Stroke
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation Study of Early Administration of Evolocumab After Thrombolysis in Patients With Atherosclerotic Acute Ischemic Stroke Ivolumab 420mg (three vials) - Acute Stroke | Phase 2 | Completed | The Affiliated Hospital of Xuzhou Medical University | 132 | 2025-10-30 | 2026-09-10 |
| Tirofiban for the Prevention of Early Neurological Deterioration After Intravenous Thrombolysis in Acute Ischemic Stroke Tirofiban Hydrochloride, Standard medical treatment (SMT) - Acute Stroke, Ischemic Stroke, Acute | Phase 2 / Phase 3 | Unknown | Capital Medical University | 302 | 2024-11-20 | 2024-10-29 |
| The Prehospital Administration of Normobaric Oxygen in Suspected Stroke NBO - Acute Stroke, Ischemic Stroke, Acute | Phase 2 | Unknown | Capital Medical University | 100 | 2022-01-21 | 2022-04-28 |
| Treatment of Acute Ischemic Stroke (ReMEDy2 Trial) Recombinant human tissue kallikrein, Placebo for DM199 Solution for Injection - Acute Stroke, Ischemic Stroke | Phase 2 / Phase 3 | Recruiting | DiaMedica Therapeutics Inc | 728 | 2021-11-07 | 2026-09-14 |
| Statin and Dual Antiplatelet Therapy to Prevent Early Neurological Deterioration in Branch Atheromatous Disease Clopidogrel, Aspirin, Atorvastatin - Acute Stroke, Dual Antiplatelet Therapy | Phase 2 | Completed | Chang Gung Memorial Hospital | 376 | 2021-03-23 | 2025-03-26 |
| Phase Ib/IIa Clinical Study of ApTOLL for the Treatment of Acute Ischemic Stroke ApTOLL, Placebo - Stroke, Acute Stroke | Phase 1 / Phase 2 | Completed | aptaTargets S.L. | 151 | 2020-10-28 | 2022-10-21 |
| Tirofiban for the Prevention of Neurological Deterioration in Acute Ischemic Stroke Tirofiban Hydrochloride, Oral antiplatelet - Acute Stroke | Phase 2 / Phase 3 | Unknown | Capital Medical University | 420 | 2020-09-12 | 2022-07-19 |
| Remote Ischemic Conditioning Paired With Endovascular Treatment for Acute Ischemic Stroke Remote ischemic conditioning., Endovascular treatment., Sham remote ischemic conditioning - Acute Stroke | Phase 2 | Unknown | Capital Medical University | 180 | 2020-08-01 | 2020-07-27 |
| Blood Pressure After Endovascular Stroke Therapy-II Nicardipine, Labetalol, Hydralazine - Acute Stroke, Endovascular Thrombectomy | Phase 2 | Completed | University of Cincinnati | 120 | 2020-01-17 | 2023-10-12 |
| Measuring Ambulation, Motor, and Behavioral Outcomes With Post-Stroke Fluoxetine in Tanzania Fluoxetine 20 MG Oral Tablet - Acute Stroke, Stroke, Ischemic | Phase 2 | Completed | Massachusetts General Hospital | 34 | 2019-11-26 | 2022-05-25 |
| Effect of Mesenchymal Stem Cells(MSCs) Transplantation for Acute Cerebral Infarction Patients human umbilical cord mesenchymal stem cells, Placebo, standardized treatment - Infarction, Middle Cerebral Artery, Infarction, Anterior Cerebral Artery | Phase 1 / Phase 2 | Unknown | Shanghai East Hospital | 120 | 2019-01-13 | 2023-04-18 |
| PMZ-1620 (Sovateltide) in Acute Ischemic Stroke Patients Normal Saline along with standard treatment, PMZ-1620 along with standard treatment - Acute Stroke, Cerebral Ischemia | Phase 2 | Completed | Pharmazz, Inc. | 40 | 2018-01-19 | 2025-05-12 |
| Safety and Efficacy of Glibenclamide Combined With Rt-PA in Acute Cerebral Embolism Glibenclamide, Placebo - Acute Stroke | Phase 2 / Phase 3 | Completed | Nanfang Hospital, Southern Medical University | 306 | 2018-01-01 | 2023-06-12 |
| Fluoxetine for Visual Recovery After Ischemic Stroke Fluoxetine, Placebo - Acute Stroke, Visual Field Loss | Phase 2 | Terminated | Bogachan Sahin | 17 | 2016-05-01 | 2021-10-13 |
| Blood Pressure Control in Acute Ischemic Stroke Early intensive BP control - Blood Pressure, Acute Stroke | Phase 2 / Phase 3 | Completed | National University of Singapore | 54 | 2014-12-01 | 2019-04-16 |
| PG2 Injection 500 mg in Acute Stroke Study (Pass) PG2, placebo - Acute Stroke | Phase 2 | Completed | China Medical University Hospital | 86 | 2012-06-01 | 2016-11-04 |
| Efficacy of Whole Extract of Licorice in Neurological Improvement of Patients After Acute Ischemic Stroke Licorice whole extract, Placebo - Acute Stroke | Phase 1 / Phase 2 | Completed | Shiraz University of Medical Sciences | 75 | 2012-06-01 | 2015-06-16 |
| Intra-arterial Magnesium Administration for Acute Stroke Magnesium Sulfate - Acute Stroke | Phase 1 / Phase 2 | Terminated | University of Southern California | 4 | 2012-03-01 | 2017-08-28 |
| Donepezil Trial for Motor Recovery in Acute Stroke Donepezil, Placebo - Acute Stroke | Phase 1 / Phase 2 | Withdrawn | Imperial College London | 2011-11-01 | 2024-04-12 | |
| PHANTOM-S: The Pre-Hospital Acute Neurological Therapy and Optimization of Medical Care in Stroke Patients - Study Stroke Emergency Mobile Unit (STEMO) - Acute Stroke | Phase 2 | Completed | Charite University, Berlin, Germany | 614 | 2011-05-01 | 2015-09-15 |
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Stroke (28) · Ischemic Stroke (15) · Cerebral Infarction (2) · Brain Edema (1) · Brain Infarction (1) · Brain Ischemia (1) · Cerebrovascular Disorders (1) · Hemianopsia (1) · Hemiplegia (1) · Hyperglycemia (1) · Infarction, Anterior Cerebral Artery (1) · Infarction, Middle Cerebral Artery (1) · Infarction, Posterior Cerebral Artery (1) · Insulin Resistance (1) · Ischemia (1)
Brain Diseases (28) · Cardiovascular Diseases (28) · Central Nervous System Diseases (28) · Nervous System Diseases (28) · Vascular Diseases (28) · Cerebrovascular Disorders (27) · Pathological Conditions, Signs and Symptoms (5) · Pathologic Processes (3) · Brain Ischemia (2) · Glucose Metabolism Disorders (2) · Infarction (2) · Ischemia (2) · Metabolic Diseases (2) · Necrosis (2) · Neurologic Manifestations (2)
Fluoxetine (2) · Insulin (2) · Tirofiban (2) · Aspirin (1) · Atorvastatin (1) · Clopidogrel (1) · DM199 (1) · Donepezil (1) · Glyburide (1) · Hydralazine (1) · Injections (1) · Labetalol (1) · Magnesium Sulfate (1) · Nicardipine (1) · Rosuvastatin Calcium (1)
Capital Medical University (4) · Assistance Publique - Hôpitaux de Paris (1) · Bogachan Sahin (1) · Chang Gung Memorial Hospital (1) · Charite University, Berlin, Germany (1) · China Medical University Hospital (1) · DiaMedica Therapeutics Inc (1) · Fudan University (1) · Imperial College London (1) · Lee Schwamm (1) · Manipal Acunova Ltd. (1) · Massachusetts General Hospital (1) · Nanfang Hospital, Southern Medical University (1) · National University of Singapore (1) · Pharmazz, Inc. (1)
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Anil Gulati (1) · Charles Burgar, MD (1) · Chung Y. Hsu, PhD (1) · Dr. Kameshwar Prasad, MBBS, MD (1) · Dr. R.S Sarkar (1) · Dr. Sharat Joshi, MBBS,MD, DM (1) · Dr. Sudesh Kumar Prabhakar, MBBS, MD, DM (1) · Dr. Usha Kant Misra, MBBS, MD, DM (1) · Eva Mistry, MBBS (1) · Farrah J Mateen, MD, PhD (1) · Gang Li, Doctor (1) · Heinrich Audebert, Prof (1) · Jay Volpi, M.D. (1) · Jeffrey Saver, MD (1) · Keith Muir, MD (1)
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K23NS113858 (1)