7 completed, 6 unknown, 3 recruiting, 2 terminated. 19 Phase 3, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 19 | Completed 7, Unknown 6, Recruiting 3, Terminated 2, Active not recruiting 1 |
| Phase 2 | 6 | Completed 3, Unknown 2, Recruiting 1 |
Follow Acute Stroke: new trials by email Literature Review of Acute Stroke trials Research Report on Acute Stroke
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Study of Efficacy and Safety of Dimephosphon® in Acute Ischemic Stroke Dimephosphon®, Placebo - Stroke, Acute Stroke | Phase 3 | Recruiting | Tatchempharmpreparaty, JSC | 184 | 2025-09-06 | 2025-09-11 |
| The Fifth INTEnsive pReventing Secondary Injury in Acute Cerebral Haemorrhage Trial Within ACT-GLOBAL Colchicine 0.5 mg, Deferoxamine Mesylate, Control (Standard treatment) - Intracerebral Hemorrhage, Spontaneous Intracerebral Hemorrhage | Phase 3 | Recruiting | The George Institute | 2000 | 2025-02-27 | 2026-07-08 |
| Tirofiban for the Prevention of Early Neurological Deterioration After Intravenous Thrombolysis in Acute Ischemic Stroke Tirofiban Hydrochloride, Standard medical treatment (SMT) - Acute Stroke, Ischemic Stroke, Acute | Phase 2 / Phase 3 | Unknown | Capital Medical University | 302 | 2024-11-20 | 2024-10-29 |
| Optimizing Early Nutrition Support in Severe Stroke-2 Trophic enteral feeding combined with supplemental parenteral nutrition, Full enteral feeding - Severe Stroke, Acute Stroke | Phase 3 | Completed | Wen Jiang-3 | 546 | 2023-12-20 | 2026-06-24 |
| Treatment of Acute Ischemic Stroke (ReMEDy2 Trial) Recombinant human tissue kallikrein, Placebo for DM199 Solution for Injection - Acute Stroke, Ischemic Stroke | Phase 2 / Phase 3 | Recruiting | DiaMedica Therapeutics Inc | 728 | 2021-11-07 | 2026-09-14 |
| Remote Ischemic Conditioning for the Treatment of Intracerebral Hemorrhage Remote ischemic conditioning, Sham remote ischemic conditioning, Standard medication therapy - Intracerebral Hemorrhage, Acute Stroke | Phase 3 | Unknown | Capital Medical University | 452 | 2021-04-22 | 2022-07-19 |
| Tirofiban for the Prevention of Neurological Deterioration in Acute Ischemic Stroke Tirofiban Hydrochloride, Oral antiplatelet - Acute Stroke | Phase 2 / Phase 3 | Unknown | Capital Medical University | 420 | 2020-09-12 | 2022-07-19 |
| Enhancement of Stroke Rehabilitation With Levodopa IMP Levodopa 100mg/Carbidopa 25mg, Matching placebo - Acute Stroke, Stroke Rehabilitation | Phase 3 | Active not recruiting | University Hospital, Basel, Switzerland | 610 | 2019-06-14 | 2024-10-15 |
| Ticagrelol Versus Aspirin in Ischemic Stroke Ticagrelor (Brilique) 90, Aspirin 75mg - Acute Stroke, Ischemic Stroke | Phase 3 | Completed | Kafrelsheikh University | 169 | 2019-05-01 | 2021-09-02 |
| Intensive Medical Therapy for High-risk Intracranial or Extracranial Atherosclerosis Intensive antiplatelet, Standard antiplatelet, Immediate high-intensity statin - Acute Stroke, Transient Ischemic Attack | Phase 3 | Unknown | Beijing Tiantan Hospital | 6100 | 2018-09-17 | 2023-07-18 |
| Safety and Efficacy of Glibenclamide Combined With Rt-PA in Acute Cerebral Embolism Glibenclamide, Placebo - Acute Stroke | Phase 2 / Phase 3 | Completed | Nanfang Hospital, Southern Medical University | 306 | 2018-01-01 | 2023-06-12 |
| Insulin Glargine Versus Regular Insulin Based Regimens in Glycemic Control After Acute Stroke Insulin Glargine, Regular Insulin - Acute Stroke, Hyperglycemia | Phase 3 | Unknown | National Taiwan University Hospital | 120 | 2015-12-01 | 2016-08-19 |
| Blood Pressure Control in Acute Ischemic Stroke Early intensive BP control - Blood Pressure, Acute Stroke | Phase 2 / Phase 3 | Completed | National University of Singapore | 54 | 2014-12-01 | 2019-04-16 |
| Endovascular Revascularization With Solitaire Device Versus Best Medical Therapy in Anterior Circulation Stroke Within 8 Hours Solitaire FR device, Medical treatment - Acute Stroke | Phase 3 | Terminated | Fundacio Ictus Malaltia Vascular | 206 | 2012-11-01 | 2016-02-03 |
| New Acute Treatment for Stroke - The Effect of Remote PERconditioning Actilyse, Thrombolysis + remote perconditioning - Acute Stroke | Phase 3 | Completed | Aarhus University Hospital | 120 | 2009-07-01 | 2011-06-23 |
| Efficacy and Safety of Continuous Intravenous Versus Usual Subcutaneous Insulin in Acute Ischemic Stroke Insulin - Acute Stroke, Acute Cerebral Ischemia | Phase 2 / Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 180 | 2007-05-01 | 2014-06-05 |
| ICTUS Study: International Citicoline Trial on Acute Stroke Citicoline, Placebo - Acute Stroke, Cerebral Infarction | Phase 3 | Terminated | Ferrer Internacional S.A. | 2298 | 2006-10-01 | 2012-06-20 |
| Intravenous Ancrod for the Treatment of Acute Ischemic Stroke Within 6 Hours After Onset of Symptoms Ancrod - Brain Infarction, Cerebral Ischemia | Phase 3 | Completed | Heidelberg University | 2006-06-22 | ||
| Treatment of Acute Stroke With Cromolyn(Single Dose) CROMOLYN, sugar pill - Acute Stroke | Phase 3 | Unknown | Wolfson Medical Center | 2010-08-05 |
Stroke (19) · Ischemic Stroke (10) · Cerebral Hemorrhage (2) · Cerebral Infarction (2) · Insulin Resistance (2) · Brain Edema (1) · Brain Infarction (1) · Brain Ischemia (1) · Cerebrovascular Disorders (1) · Deglutition Disorders (1) · Hyperglycemia (1) · Ischemia (1) · Ischemic Attack, Transient (1) · Pneumonia (1) · Vascular Diseases (1)
Brain Diseases (19) · Cardiovascular Diseases (19) · Central Nervous System Diseases (19) · Nervous System Diseases (19) · Cerebrovascular Disorders (18) · Vascular Diseases (18) · Pathologic Processes (6) · Pathological Conditions, Signs and Symptoms (6) · Brain Ischemia (3) · Infarction (3) · Ischemia (3) · Necrosis (3) · Brain Infarction (2) · Glucose Metabolism Disorders (2) · Hemorrhage (2)
Aspirin (2) · Insulin (2) · Tirofiban (2) · Ancrod (1) · Carbidopa (1) · Colchicine (1) · Cromolyn Sodium (1) · Cytidine Diphosphate Choline (1) · DM199 (1) · Deferoxamine (1) · Fibrinolytic Agents (1) · Glyburide (1) · Injections (1) · Insulin Glargine (1) · Sugars (1)
Capital Medical University (3) · Aarhus University Hospital (1) · Assistance Publique - Hôpitaux de Paris (1) · Beijing Tiantan Hospital (1) · DiaMedica Therapeutics Inc (1) · Ferrer Internacional S.A. (1) · Fundacio Ictus Malaltia Vascular (1) · Heidelberg University (1) · Kafrelsheikh University (1) · Nanfang Hospital, Southern Medical University (1) · National Taiwan University Hospital (1) · National University of Singapore (1) · Tatchempharmpreparaty, JSC (1) · The George Institute (1) · University Hospital, Basel, Switzerland (1)
China (7) · Spain (3) · France (2) · Australia (1) · Belgium (1) · Canada (1) · Denmark (1) · Egypt (1) · Georgia (1) · Germany (1) · Hungary (1) · Israel (1) · Poland (1) · Portugal (1) · Romania (1)
Ahmed I Elbassiouny, MD (1) · Alex Rovira, MD (1) · Angel Chamorro, MD (1) · Carlos Molina, MD (1) · Erik Cobo, MD (1) · Grethe Andersen, M.D Doctor (1) · Hala M Elkhawas, MD (1) · Hani Mohamed M Aref, MD (1) · Hossam S Mohammed, MD (1) · Jay Volpi, M.D. (1) · Jean M Orgogozo, MD (1) · Jiann-Shing Jeng, MD. PhD (1) · Joaquin Serena, MD (1)
PMID 38648030, PMID 16614616, PMID 17126719, PMID 22691567, PMID 22700528, PMID 24203849, PMID 25428822, PMID 25793765, PMID 25882510, PMID 26508752, PMID 26542697, PMID 26956258, PMID 27160892, PMID 27940648, PMID 28292867, PMID 28318984, PMID 29127270, PMID 29170266, PMID 30045949, PMID 30290680, PMID 31570084, PMID 32527232, PMID 34075142, PMID 34515113, PMID 36446950, PMID 36707080, PMID 37256974, PMID 37965431, PMID 38157499, PMID 38805216, PMID 39036300, PMID 39240565, PMID 39270151, PMID 39705390, PMID 39931900, PMID 39950764, PMID 40012523, PMID 40190261, PMID 40251953, PMID 40673545, PMID 40964718, PMID 40982270, PMID 41650951, PMID 41701756, PMID 41991239, PMID 42011250, PMID 42348803, PMID 42390058, PMID 42430849, PMID 42525438
2018 (1)