105 completed, 48 unknown, 26 recruiting, 14 terminated. 88 Not applicable, 28 Phase 2, 19 Phase 3, 11 Phase 1, 9 Phase 4.
Follow Acute Stroke: new trials by email Literature Review of Acute Stroke trials Research Report on Acute Stroke
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Essential Acute Stroke Care in Low Resource Settings: a Pilot studY Acute stroke care Intervention arm - Acute Stroke | Not applicable | Not yet recruiting | The George Institute | 300 | 2027-12-30 | 2026-06-11 |
| Effect of Early Tendon Vibrations on Upper Limb Motor Recovery After a Stroke TVS rehabilitation sessions - Acute Stroke, Upper Limb Motor Deficit | Not applicable | Not yet recruiting | Centre Hospitalier Régional d'Orléans | 54 | 2026-11-03 | 2026-10-29 |
| Impact of Stroke Unit Care on Acute Stroke Outcomes Acute Stroke, Ischemic Stroke | Not yet recruiting | Assiut University | 140 | 2026-09-01 | 2026-08-06 | |
| Effect of tDCS Timing on Motor Recovery in Acute Stroke Rehabilitation tDCS, Sham Transcranial Direct Current Stimulation (Sham tDCS) - Acute Stroke | Not applicable | Not yet recruiting | University of Liege | 60 | 2026-09-01 | 2026-07-02 |
| Sarcopenia in Acute Ischemic Stroke Sarcopenia, Acute Stroke | Recruiting | University Clinical Hospital na V.V.Vinogradov (branch of RUDN university na Patrice Lumumba) | 400 | 2026-08-01 | 2026-10-22 | |
| Unimanual Versus Bimanual Motor Skill Learning in Acute and Chronic Stroke REAplan®, Dextrain® Manipulandum - Acute Stroke, Chronic Stroke Patient | Not applicable | Recruiting | University Hospital of Mont-Godinne | 200 | 2026-05-18 | 2026-09-17 |
| Effectiveness of Best Care Practices in Acute Stroke in Conventional Hospitalization (BEST CARE ICTUS_HC) BEST CARE ICTUS_HC BUNDLE - Stroke, Acute Stroke | Not applicable | Recruiting | University of Malaga | 700 | 2026-05-12 | 2026-06-04 |
| Low-Field MRI in Stroke Code Patients Low-field MRI - Acute Stroke, MRI Imaging | Recruiting | Leiden University Medical Center | 80 | 2026-04-20 | 2026-07-16 | |
| Short Term Effects of Early Respiratory Muscle Training on Respiratory Muscle Strength in Inpatient Acute Stroke High-Intensity Interval Inspiratory and Expiratory Muscle Training (H-IIIEMT), Control Group - Stroke, Acute Stroke | Not applicable | Active not recruiting | Prof. R. D. Kandou General Hospital | 24 | 2026-04-01 | 2026-08-18 |
| Continuous Dual Aspiration Technique With Zoom System for Stroke Zoom System - Ischemic Stroke, Acute Stroke | Recruiting | Imperative Care, Inc. | 750 | 2026-03-24 | 2026-10-20 | |
| Early Administration of PCSK9 Inhibitors After Thrombectomy for Atherosclerotic Acute Ischemic Stroke: A Randomized Controlled Trial Evolocumab(420 mg injections) - Acute Stroke | Phase 4 | Completed | The Affiliated Hospital of Xuzhou Medical University | 60 | 2025-12-20 | 2026-07-13 |
| mSOAR and Early Mortality in Acute Stroke No Intervention (Observational Study) - Acute Stroke | Recruiting | Sohag University | 60 | 2025-11-01 | 2026-01-28 | |
| Evaluation Study of Early Administration of Evolocumab After Thrombolysis in Patients With Atherosclerotic Acute Ischemic Stroke Ivolumab 420mg (three vials) - Acute Stroke | Phase 2 | Completed | The Affiliated Hospital of Xuzhou Medical University | 132 | 2025-10-30 | 2026-09-10 |
| Isolated Versus Synergetic Muscle Facilitation on Upper Limb Functional Performance in Acute Stroke standard physical therapy program, isolated muscle facilitation, synergetic muscle facilitation program - Acute Stroke | Not applicable | Recruiting | Cairo University | 40 | 2025-10-01 | 2025-12-09 |
| Impact of Early, Personalized Nutritional Management on 1-month Mortality After Acute Stroke Early nutritional management - Acute Stroke | Not applicable | Recruiting | University Hospital, Angers | 3084 | 2025-09-19 | 2026-09-01 |
| Effect of Virtual Reality on Agitation in Acute Stroke Virtual Reality Application, Standard Care (in control arm) - Acute Stroke, Psychomotor Agitation | Not applicable | Completed | Ankara Etlik City Hospital | 68 | 2025-09-08 | 2026-08-26 |
| The Study of Efficacy and Safety of Dimephosphon® in Acute Ischemic Stroke Dimephosphon®, Placebo - Stroke, Acute Stroke | Phase 3 | Recruiting | Tatchempharmpreparaty, JSC | 184 | 2025-09-06 | 2025-09-11 |
| Focal Muscle Vibrations in Acute Stroke Repeated Muscle Vibration (rMV) - Acute Stroke | Not applicable | Withdrawn | Centre Hospitalier Régional d'Orléans | 2025-09-01 | 2025-07-10 | |
| Role of MRI in the Early Diagnosis and Management of Acute Stroke and Its Impact on Turnaround Time in Emergency Settings Magnetic Resonance Imaging - Magnetic Resonance Imaging, Diagnosis | Recruiting | Tanta University | 136 | 2025-08-23 | 2025-08-26 | |
| Mirror Therapy for Hand Function Recovery in Acute Stroke Mirror Therapy Conventional Physiotherapy - Acute Stroke | Not applicable | Recruiting | Riphah International University | 44 | 2025-08-15 | 2025-10-02 |
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Stroke (208) · Ischemic Stroke (53) · Brain Ischemia (9) · Deglutition Disorders (9) · Hemorrhagic Stroke (8) · Ischemic Attack, Transient (8) · Cerebral Infarction (6) · Cerebrovascular Disorders (6) · Disease (6) · Ischemia (5) · Brain Infarction (4) · Cerebral Hemorrhage (4) · Hyperglycemia (4) · Paresis (4) · Cardiovascular Diseases (3)
Nervous System Diseases (208) · Brain Diseases (206) · Vascular Diseases (206) · Cardiovascular Diseases (205) · Central Nervous System Diseases (205) · Cerebrovascular Disorders (202) · Pathological Conditions, Signs and Symptoms (39) · Pathologic Processes (27) · Brain Ischemia (14) · Signs and Symptoms (13) · Neurologic Manifestations (12) · Necrosis (10) · Digestive System Diseases (9) · Esophageal Diseases (9) · Gastrointestinal Diseases (9)
Tissue Plasminogen Activator (5) · Transcranial Direct Current Stimulation (4) · Aspirin (3) · Control Groups (3) · Insulin (3) · Magnetic Resonance Imaging (3) · Standard of Care (3) · Acupuncture Therapy (2) · Blood Specimen Collection (2) · Fibrinolytic Agents (2) · Fluoxetine (2) · Injections (2) · Methods (2) · Metoclopramide (2) · Observation (2)
Assiut University (7) · Capital Medical University (6) · Fondation Ophtalmologique Adolphe de Rothschild (5) · Can Tho Stroke International Services Hospital (4) · National Taiwan University Hospital (4) · Centre Hospitalier Régional d'Orléans (3) · IRCCS San Raffaele Roma (3) · University of Liege (3) · University of Texas Southwestern Medical Center (3) · Acandis GmbH (2) · Assistance Publique - Hôpitaux de Paris (2) · Beijing Tiantan Hospital (2) · Centre Hospitalier St Anne (2) · Charite University, Berlin, Germany (2) · China Academy of Chinese Medical Sciences (2)
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Cuong Tran Chi, Doctor (3) · Marco Franceschini, MD (3) · William J Mack, MD (3) · Asad Ikram, MD (2) · Atif Zafar, MD (2) · Jeffrey Saver, MD (2) · Karen J McCain, PT, DPT, NCS (2) · Michel Torbey, MD, MPH (2) · Mudassir Farooqui, MD, MPH (2) · Sanaz Pournajaf, Dr (2) · Suyue Pan, M.D., Ph.D. (2) · Wen Jiang, PhD (2) · Yves Vandermeeren, MD, PhD (2) · Ahmed I Elbassiouny, MD (1)
PMID 23370205, PMID 25671797, PMID 25882510, PMID 35857365, PMID 38648030, PMID 10990547, PMID 12750536, PMID 12817109, PMID 12917305, PMID 14726553, PMID 15733717, PMID 16282547, PMID 16336965, PMID 16614616, PMID 17126719, PMID 17157679, PMID 17258667, PMID 18396107, PMID 18468545, PMID 18701066, PMID 19058760, PMID 19423851, PMID 19570514, PMID 19995432, PMID 20130154, PMID 20621562, PMID 20966420, PMID 20971534, PMID 21068427, PMID 21825004, PMID 21885841, PMID 22307571, PMID 22308240, PMID 22448901, PMID 22497929, PMID 22673593, PMID 22691567, PMID 22700528, PMID 22818804, PMID 22960888, PMID 22961962, PMID 23069890, PMID 23084320, PMID 23192756, PMID 23197640, PMID 23287785, PMID 23449267, PMID 23523460, PMID 23633218, PMID 23713578
2018 (2), K23NS113858 (1), R01NS045049 (1), R44AG044639 (1), U44NS094307 (1)