6 completed, 2 unknown, 2 withdrawn, 1 terminated. 11 Phase 1, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 11 | Completed 6, Unknown 2, Withdrawn 2, Terminated 1 |
| Phase 2 | 5 | Completed 2, Terminated 1, Unknown 1, Withdrawn 1 |
Follow Acute Stroke: new trials by email Literature Review of Acute Stroke trials Research Report on Acute Stroke
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluate the Safety and Explore Efficacy of Umbilical Cord Mesenchymal Stem Cells in Acute Ischemic Stroke UMSC01 - Acute Stroke | Phase 1 | Completed | Ever Supreme Bio Technology Co., Ltd. | 10 | 2020-12-02 | 2026-09-23 |
| Phase Ib/IIa Clinical Study of ApTOLL for the Treatment of Acute Ischemic Stroke ApTOLL, Placebo - Stroke, Acute Stroke | Phase 1 / Phase 2 | Completed | aptaTargets S.L. | 151 | 2020-10-28 | 2022-10-21 |
| Effect of Mesenchymal Stem Cells(MSCs) Transplantation for Acute Cerebral Infarction Patients human umbilical cord mesenchymal stem cells, Placebo, standardized treatment - Infarction, Middle Cerebral Artery, Infarction, Anterior Cerebral Artery | Phase 1 / Phase 2 | Unknown | Shanghai East Hospital | 120 | 2019-01-13 | 2023-04-18 |
| Remote Ischemic Conditioning Paired With Endovascular Treatment for Acute Ischemic Stroke (REVISE-1) Remote ischemic conditioning, Endovascular treatment - Acute Stroke | Phase 1 | Completed | Capital Medical University | 20 | 2017-07-07 | 2017-12-22 |
| The Capillary Index Score Trial Endovascular Treatment (EVT) - Acute Stroke, Brain Ischemia | Phase 1 | Completed | Firas Al-Ali | 57 | 2016-03-01 | 2020-02-05 |
| Effects of a Ketogenic Diet on Acute Stroke Ketocal 4:1 (Nutricia), Control diet: Regular diet offered at the hospitals, Ketogenic meals - Acute Stroke | Phase 1 | Completed | University of Copenhagen | 64 | 2013-05-01 | 2014-07-18 |
| Efficacy of Whole Extract of Licorice in Neurological Improvement of Patients After Acute Ischemic Stroke Licorice whole extract, Placebo - Acute Stroke | Phase 1 / Phase 2 | Completed | Shiraz University of Medical Sciences | 75 | 2012-06-01 | 2015-06-16 |
| Intra-arterial Magnesium Administration for Acute Stroke Magnesium Sulfate - Acute Stroke | Phase 1 / Phase 2 | Terminated | University of Southern California | 4 | 2012-03-01 | 2017-08-28 |
| Donepezil Trial for Motor Recovery in Acute Stroke Donepezil, Placebo - Acute Stroke | Phase 1 / Phase 2 | Withdrawn | Imperial College London | 2011-11-01 | 2024-04-12 | |
| Study of Robot-assisted Arm Therapy for Acute Stroke Patients Reo Go robotic arm trainer, Conventional Therapy - Acute Stroke, Paresis | Phase 1 | Unknown | Kessler Foundation | 40 | 2008-09-01 | 2009-12-24 |
| A Study to Evaluate the Effects of the Neuroflo Device in People Who Have Had a Stroke NeuroFlo - Acute Stroke | Phase 1 | Withdrawn | University of California, Los Angeles | 2008-03-01 | 2017-01-12 |
Stroke (11) · Ischemic Stroke (5) · Brain Infarction (1) · Brain Ischemia (1) · Cerebral Infarction (1) · Hyperglycemia (1) · Infarction, Anterior Cerebral Artery (1) · Infarction, Middle Cerebral Artery (1) · Infarction, Posterior Cerebral Artery (1) · Ischemia (1) · Ketosis (1) · Paresis (1)
Brain Diseases (11) · Cardiovascular Diseases (11) · Central Nervous System Diseases (11) · Cerebrovascular Disorders (11) · Nervous System Diseases (11) · Vascular Diseases (11) · Pathological Conditions, Signs and Symptoms (3) · Pathologic Processes (2) · Acid-Base Imbalance (1) · Acidosis (1) · Brain Ischemia (1) · Cerebral Arterial Diseases (1) · Glucose Metabolism Disorders (1) · Infarction (1) · Intracranial Arterial Diseases (1)
Donepezil (1) · Magnesium Sulfate (1) · TLR4 antagonist ApTOLL (1)
Capital Medical University (1) · Ever Supreme Bio Technology Co., Ltd. (1) · Firas Al-Ali (1) · Imperial College London (1) · Kessler Foundation (1) · Shanghai East Hospital (1) · Shiraz University of Medical Sciences (1) · University of California, Los Angeles (1) · University of Copenhagen (1) · University of Southern California (1) · aptaTargets S.L. (1)
United States (4) · China (2) · Denmark (1) · France (1) · Germany (1) · Iran (1) · Spain (1) · Taiwan (1) · United Kingdom (1)
Chon-Haw Tsai, MD (1) · David S. Liebeskind, M.D. (1) · Firas Al-Ali, MD (1) · Gang Li, Doctor (1) · Jeffrey Saver, MD (1) · Jens Rikardt Andersen, MD (1) · Lauren McDonagh, PT (1) · Paul Bentley, MA MRCP PhD (1) · Sidney Starkman, M.D. (1) · William J Mack, MD (1)
PMID 16282547, PMID 16336965, PMID 18468545, PMID 19570514, PMID 20966420, PMID 23197640, PMID 23370205, PMID 24610327, PMID 25530442, PMID 25671797, PMID 34174279, PMID 36908619, PMID 37338893