15 completed, 5 unknown, 3 terminated, 1 active not recruiting. 26 Phase 1, 10 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 26 | Completed 15, Unknown 5, Terminated 3, Active not recruiting 1, Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 10 | Completed 5, Unknown 4, Terminated 1 |
Follow Wound Infection: new trials by email Literature Review of Wound Infection trials Research Report on Wound Infection
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Study on Nitropaste Using Intraoperative SPY Imaging. Nitroglycerin Ointment 2% - Achilles Tendon Repairs/Reconstructions, Pilon Fracture of Tibia | Phase 1 | Not yet recruiting | Johns Hopkins University | 15 | 2026-11-01 | 2026-03-31 |
| A Study of Amicidin-β Topical Solution for Patients With Surgical or Traumatic Wound Infections Amicidin-β topical solution - 15 mL, Amicidin-β topical solution - 50 mL, Standard of Care (SOC) - Surgical Wound Infection, Traumatic Wound Infection | Phase 1 | Recruiting | Macro Biologics, Inc. | 44 | 2026-09-30 | 2026-08-17 |
| Precision Antibiotic Dosing for Appendectomy Cefoxitin - Appendicitis (Diagnosis) | Phase 1 | Active not recruiting | University of Michigan | 46 | 2025-02-28 | 2026-08-14 |
| Clinical Trial to Demonstrate the Safety and Efficacy of DUOFAG® IMP, Placebo - Surgical Site Infection, Staphylococcus Aureus Infection | Phase 1 / Phase 2 | Unknown | MB PHARMA s.r.o. | 52 | 2023-10-27 | 2024-03-19 |
| Red Light Photobiomodulation and Topical Disinfectants Methylene Blue Only, Chlorhexidine Gluconate Only, Methylene Blue + Chlorhexidine Gluconate - Healthcare Associated Infection, Nosocomial Infection | Phase 1 / Phase 2 | Completed | Ondine Biomedical Inc. | 28 | 2023-01-10 | 2023-04-04 |
| Phage Therapy for the Prevention and Treatment of Pressure Ulcers. Bacteriophage-loaded Microcapsule Spray, Placebo, Standard of Care - Pressure Ulcer | Phase 1 / Phase 2 | Unknown | Precisio Biotix Therapeutics, Inc. | 69 | 2022-01-01 | 2021-12-21 |
| Phage Therapy for the Prevention and Treatment of Wound Infections in Burned Patients Bacteriophage cocktail spray, Xeroform - Wound Infection | Phase 1 | Unknown | Precisio Biotix Therapeutics, Inc. | 12 | 2022-01-01 | 2021-12-22 |
| Tebipenem (SPR994) Tissue Penetration in Diabetic Patients With Wound Infections and Healthy Volunteers Via In Vivo Microdialysis Tebipenem Pivoxil Hydrobromide - Diabetes, Wound Infection | Phase 1 | Completed | Hartford Hospital | 12 | 2021-07-01 | 2023-10-23 |
| Chlorhexidine Vaginal Preparation for Reduction of Post-cesarean Endometritis and Sepsis Chlorhexidine Gluconate vaginal solution 0.05% - Postpartum Endometritis, Wound Infection | Phase 1 / Phase 2 | Completed | Zagazig University | 840 | 2020-05-15 | 2022-09-23 |
| Omadacycline Tissue Penetration in Diabetic Patients With Wound Infections and Healthy Volunteers Via In Vivo Microdialysis Omadacycline, Microdialysis Catheter Insertion - Diabetes, Wound Infection | Phase 1 | Completed | Hartford Hospital | 14 | 2020-02-10 | 2021-08-25 |
| Pharmacokinetic Study of Vancomycin, Clindamycin And/or Gentamicin Administration During Surgery Using a Microdialysis Procedure Blood and microdialysis samples - Surgical Site Infection | Phase 1 | Completed | Poitiers University Hospital | 25 | 2019-05-26 | 2025-01-16 |
| Prophylactic Antibiotics After Cesarean Cephalexin, Placebo, Metronidazole - Surgical Site Infection | Phase 1 | Completed | The University of Texas Medical Branch, Galveston | 321 | 2017-08-01 | 2023-08-16 |
| Tedizolid Tissue Penetration in Diabetic Patients With Wound Infections and Healthy Volunteers Via In Vivo Microdialysis Tedizolid, Microdialysis Catheter Insertion - Diabetes, Wound Infection | Phase 1 | Completed | Hartford Hospital | 18 | 2016-02-23 | 2019-01-15 |
| Tissue Penetration of Ceftolozane/Tazobactam in Diabetic Patients With Lower Limb Infections Ceftolozane/tazobactam, Microdialysis Catheter Insertion - Diabetes, Wound Infection | Phase 1 | Completed | Hartford Hospital | 16 | 2016-02-19 | 2019-01-15 |
| Evaluation of Phage Therapy for the Treatment of Escherichia Coli and Pseudomonas Aeruginosa Wound Infections in Burned Patients E. coli Phages cocktail, Standard of care : Silver Sulfadiazine, P. Aeruginosa, Phages cocktail - Wound Infection | Phase 1 / Phase 2 | Unknown | Phagenix | 2015-07-01 | 2015-07-24 | |
| Vacuum Assisted Closure for Cesarean Section Vacuum-assisted closure, Standard sterile dressing - Surgical Wound Infection | Phase 1 | Terminated | Dartmouth-Hitchcock Medical Center | 166 | 2015-05-01 | 2018-05-22 |
| A Phase I/II Double-Blind, Randomized, Controlled Study to Evaluate the Safety and Efficacy of RUT058-60 RUT058-60, Sterile saline for irrigation - Postoperative Wound Infection-deep, Post Operative Wound Infection | Phase 1 / Phase 2 | Terminated | Pulmatrix Inc. | 9 | 2014-10-01 | 2021-01-12 |
| Safety Study to Evaluate the Contact Sensitizing Potential of Topically Applied ZuraPrep™ and ZuraPrep™ Without IPA Chloraprep, 0.9% Physiological Saline, ZuraPrep without IPA - Surgical Site Infection | Phase 1 | Completed | Zurex Pharma, Inc. | 208 | 2014-07-01 | 2015-03-17 |
| Negative Pressure Wound Therapy for the Prevention of Surgical Site Infection Following Lower Limb Revascularization Prevena (Negative Pressure Wound Therapy Device), Standard Tegaderm (3M Healthcare, St. Paul, MN) adhesive dressing - Surgical Wound Infection, Peripheral Vascular Diseases | Phase 1 / Phase 2 | Unknown | Western University, Canada | 80 | 2014-07-01 | 2015-07-31 |
| Safety Study to Evaluate the Cumulative Irritation Potential of Topically Applied ZuraPrep™ and ZuraPrep™ Without IPA ChloraPrep, 0.1% Sodium Lauryl Sulfate, 0.9% Physiological Saline - Surgical Site Infection | Phase 1 | Completed | Zurex Pharma, Inc. | 40 | 2014-06-01 | 2014-10-27 |
Showing 20 of 26. Sign in to see all of them.
Surgical Wound Infection (15) · Diabetes Mellitus (4) · Pseudomonas Infections (3) · Staphylococcal Infections (3) · Bacterial Infections (2) · Burns (2) · Infections (2) · Ankle Fractures (1) · Appendicitis (1) · Cross Infection (1) · Degloving Injuries (1) · Disease (1) · Peripheral Vascular Diseases (1) · Pressure Ulcer (1)
Infections (24) · Pathologic Processes (16) · Pathological Conditions, Signs and Symptoms (16) · Postoperative Complications (16) · Endocrine System Diseases (4) · Glucose Metabolism Disorders (4) · Metabolic Diseases (4) · Nutritional and Metabolic Diseases (4) · Bacterial Infections and Mycoses (3) · Gram-Negative Bacterial Infections (3) · Gram-Positive Bacterial Infections (3) · Wounds and Injuries (3) · Ankle Injuries (1) · Bacterial Infections (1)
Ethanol (2) · Metronidazole (2) · Negative-Pressure Wound Therapy (2) · Standard of Care (2) · chlorhexidine gluconate (2) · citrate, isopropyl alcohol, methylene blue, parabens drug combination (2) · 2,4,6-tribromophenol (1) · 2-Propanol (1) · Blood Specimen Collection (1) · Cefazolin (1) · Cefoxitin (1) · Cephalexin (1) · Gramicidin, Neomycin Sulfate, Nystatin, Triamcinolone Acetonide Drug Combination (1) · Inosine Monophosphate (1) · Sodium Chloride (1)
Hartford Hospital (4) · Precisio Biotix Therapeutics, Inc. (2) · Zurex Pharma, Inc. (2) · American Heart Association (1) · Dartmouth-Hitchcock Medical Center (1) · Dr. Reddy's Laboratories Limited (1) · Johns Hopkins University (1) · Klein, Jeffrey A., M.D. (1) · MB PHARMA s.r.o. (1) · Macro Biologics, Inc. (1) · Ondine Biomedical Inc. (1) · Phagenix (1) · Poitiers University Hospital (1) · Pulmatrix Inc. (1) · Stratatech, a Mallinckrodt Company (1)
United States (18) · France (2) · Belgium (1) · Canada (1) · Czechia (1) · Kenya (1) · Saudi Arabia (1) · Switzerland (1)
David P Nicolau, PharmD (3) · Adam Power, MD (1) · Ahmed Shafiek (1) · AnaMaria Garza, MD (1) · Antonio F Saad, MD (1) · Babar Shafi, MD, MSPT (1) · Esther Campbell (1) · Gina Suh, M.D. (1) · Harold L Lazar MD (1) · Harold Minkowitz, MD (1) · Hector Bolivar, M.D. (1) · Henry T Shu, MD (1) · Hytham Atia (1) · Karin Zachow, M.D. (1) · Kent Allenby, MD (1)
PMID 19276766, PMID 20878941, PMID 21475006, PMID 21554389, PMID 22297835, PMID 26537879, PMID 27313846, PMID 28865981, PMID 28893779, PMID 29995726, PMID 30292481, PMID 40260835, PMID 40403315, PMID 41159585
R44AR047499 (1)