249 completed, 67 recruiting, 31 terminated, 24 active not recruiting. 236 Not applicable, 52 Phase 2, 28 Phase 1, 23 Phase 4, 11 Early Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vitamin B6 on Exercise Pressor Reflex on Leg Ischemia-reperfusion Vitamin B6 25 MG, Vitamin B6 50 MG, Vitamin B6 100 MG - Ischemia Reperfusion Injury, Peripheral Artery Disease | Early Phase 1 | Not yet recruiting | Milton S. Hershey Medical Center | 30 | 2027-12-01 | 2026-03-17 |
| Optimal Targeted High-definition Transcranial Direct Current Stimulation for Reducing Post-stroke Upper Limb Motor Impairments High-definition transcranial direct stimulation: sham, High-definition transcranial direct stimulation: optimal, Modified constraint-induced movement therapy - Hemiparetic Stroke | Not applicable | Not yet recruiting | Carle Foundation Hospital | 16 | 2026-11-15 | 2026-10-21 |
| Adapting Enhanced Supports to Improve Patient Adherence to Secondary Antibiotic Prophylaxis for Rheumatic Heart Disease CHW Delivered SAP Adherence Supports - Rheumatic Heart Disease in Children | Not yet recruiting | Children's Hospital Medical Center, Cincinnati | 308 | 2026-11-01 | 2026-10-13 | |
| CGM Use in Heart Failure Libre 2 rt-CGM, POC BG + Blinded CGM - Heart Failure, Diabetes Mellitus | Not applicable | Not yet recruiting | Emory University | 140 | 2026-11-01 | 2026-07-22 |
| Telerehabilitation for Post-Stroke Hand Function Technology-Supported Hand Training, Pamphlet-Supported Hand Activity - Stroke | Not applicable | Recruiting | University of Michigan | 22 | 2026-10-13 | 2026-10-15 |
| Feasibility of an Implementation Strategy for a Physical Activity Program in Rural Middle Schools Goal-Setting in Sport-Based Youth Development, No Goal-Setting Program - Goal-Setting | Not applicable | Recruiting | Indiana University | 80 | 2026-10-01 | 2026-10-08 |
| [11C]PS13 PET Imaging of Neuroinflammation in Heart Failure With Reduced Ejection Fraction [11C]PS13: [carbon-11]PS13; COX-1 PET radioligand, Sacubitril-Valsartan - Heart Failure With Reduced Ejection Fraction, Cognitive Impairment, Mild | Phase 1 | Not yet recruiting | Stony Brook University | 18 | 2026-10-01 | 2026-10-02 |
| Integrating Values Based Communication in Heart Failure Management Serious Illness Care Program for Heart Failure (SICP-HF) - Heart Failure | Not applicable | Not yet recruiting | Abigail Latimer | 200 | 2026-10-01 | 2026-08-31 |
| Evaluating an Implementation Strategy to Improve Physical Activity and Reduce Cardiovascular Risk Factors in Children MAGIC, Control - Physical Activity | Not applicable | Recruiting | The University of Texas Health Science Center, Houston | 350 | 2026-09-15 | 2026-10-14 |
| Neuroplastic Changes Due to an Exercise Intervention That Aid in Lower Limb Recovery After Subcortical Stroke HIIT intervention - Subcortical Lesions, Stroke | Not applicable | Recruiting | Emory University | 55 | 2026-09-01 | 2026-08-20 |
| Handgrip Exercise Training and CKD Isometric handgrip exercise training, Sham Training - Chronic Kidney Diseases | Not applicable | Not yet recruiting | Emory University | 50 | 2026-09-01 | 2026-06-10 |
| Ventilation Performance and Feedback Simulation Trial Real-time feedback - Out-of-hospital Cardiac Arrest (OHCA) | Not applicable | Recruiting | University of Texas Southwestern Medical Center | 80 | 2026-08-31 | 2026-09-03 |
| Exercise Activity Intervention With Sensor-Based Engagement in Patients With Atrial Fibrillation Physical Activity Intervention Using FitBit Wearable Device - Atrial Fibrillation, Arrhythmias, Cardiac | Not applicable | Recruiting | Icahn School of Medicine at Mount Sinai | 120 | 2026-08-11 | 2026-08-24 |
| Home-based Vision Rehabilitation Guided by Brain Imaging High-level perceptual learning-based training, Low-level perceptual learning-based training - Visual Field Defect, Stroke | Not applicable | Recruiting | Georgetown University | 100 | 2026-07-23 | 2026-09-14 |
| Increasing Law Enforcement Application of Automated External Defibrillators (AED)s for Cardiac Arrest AED training adjunct - Heart Arrest, Out-Of-Hospital, Defibrillators | Not applicable | Enrolling by invitation | Wayne State University | 30 | 2026-07-14 | 2026-08-19 |
| Sotagliflozin as Prevention of Anthracycline-Related Cardiotoxicity Sotagliflozin, Placebo - Anthracycline-induced Cardiotoxicity, Lymphoma | Phase 2 | Not yet recruiting | Icahn School of Medicine at Mount Sinai | 60 | 2026-07-01 | 2026-05-07 |
| Integrating Free-choice Marketplace, dieTitian coacHing, cultuRally Tailored messagIng to improVE Blood Pressure iTHRIVE intervention, Active comparator - Hypertension, Hypertension Complicated With Type 2 Diabetes | Not applicable | Recruiting | Johns Hopkins University | 100 | 2026-06-25 | 2026-06-30 |
| EXercise and Activin Inhibition to Modulate InflammatioN Effects on Heart Failure and Cognition (EXAMINE-HFC) Activin ligand-trap biological therapy, Placebo, Normal Saline - Heart Failure With Preserved Ejection Fraction | Phase 2 | Recruiting | Massachusetts General Hospital | 48 | 2026-06-03 | 2026-07-09 |
| Implementation of a Beauty Salon-Based Strategy for Blood Pressure Management Among Women CROWN Intervention, Enhanced Usual Care - Hypertension | Not applicable | Recruiting | Johns Hopkins University | 144 | 2026-05-29 | 2026-09-08 |
| Feasibility of The Health Integrated Nutrition and Kidney Wellness Program THINK-Well, Enhanced Usual Care - Chronic Kidney Disease, Cardiovascular Disease | Not applicable | Recruiting | University of Pittsburgh | 45 | 2026-04-24 | 2026-09-09 |
Showing 20 of 412. Sign in to see all of them.
Cardiovascular Diseases (45) · Stroke (43) · Hypertension (41) · Heart Failure (36) · Obesity (35) · Motor Activity (26) · Atrial Fibrillation (15) · Diabetes Mellitus, Type 2 (14) · Coronary Artery Disease (13) · Ischemic Stroke (13) · Diabetes Mellitus (12) · Heart Arrest (12) · Peripheral Arterial Disease (11) · Inflammation (10) · Overweight (9)
Saline Solution (10) · Sodium Chloride (6) · Exercise (5) · Atorvastatin (4) · Control Groups (4) · Interleukin 1 Receptor Antagonist Protein (4) · Transcranial Direct Current Stimulation (4) · Blood Specimen Collection (3) · Community Health Workers (3) · Diet (3) · Progesterone (3) · Simvastatin (3) · Transcranial Magnetic Stimulation (3) · ibutilide (3) · Aspirin (2)
United States (397) · Canada (5) · China (3) · Australia (1)
Bonnie Ky, MD, MSCE (3) · James E Tisdale, PharmD (3) · Javed Butler, MD (3) · Oluwabunmi Ogungbe, PhD, MPH, RN (3) · Angela Fagerlin, PhD (2) · Cyndya Shibao, M.D (2) · Dong Zhao, Ph. D (2) · Ela Plow, PhD (2) · Harold L Lazar MD (2) · Jeanie Park, MD (2) · Jeffrey M Levsky, MD, PhD (2) · Joshua Joseph, MD (2) · Lauren Eberly, MD, MPH (2) · Michelle A Albert, MD (2) · Rachel Sinkey, MD (2)
PMID 36207229, PMID 21865944, PMID 10564301, PMID 12679447, PMID 12680494, PMID 15507261, PMID 15598683, PMID 15671108, PMID 18322548, PMID 18404076, PMID 19767408, PMID 19909549, PMID 19958860, PMID 20923960, PMID 21386066, PMID 21406672, PMID 21412912, PMID 21554389, PMID 21879896, PMID 22080629, PMID 22128195, PMID 23082133, PMID 23122795, PMID 23124047, PMID 23184900, PMID 23229846, PMID 23453459, PMID 23463811, PMID 23583255, PMID 23759474, PMID 23782741, PMID 24221839, PMID 24369008, PMID 24467979, PMID 24528783, PMID 24533209, PMID 24572255, PMID 24717343, PMID 24733277, PMID 24906491, PMID 25009491, PMID 25120466, PMID 25121719, PMID 25252721, PMID 25296334, PMID 25344064, PMID 25344549, PMID 25355838, PMID 25482680, PMID 25565457
U01HL077863 (4), K23HL161348 (2), U54EB015408 (2), 3UM1AI068614-14S1 (1), 4UH3NS119702-02 (1), F32HL143916 (1), K01HD079584 (1), K12DA000167 (1), K12TR004413 (1), K23DK099237 (1), K23DK129836 (1), K23HD080837 (1), K23HL127099 (1), K23HL147799 (1), K23HL159312 (1)