1268 completed, 207 unknown, 148 recruiting, 73 terminated. 399 Phase 3, 346 Phase 2, 291 Not applicable, 241 Phase 4, 184 Phase 1.
Follow Gram-Negative Bacterial Infections: new trials by email Literature Review of Gram-Negative Bacterial Infections trials Research Report on Gram-Negative Bacterial Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in Veterans Integrated care - Opioid Use Disorder, HIV | Not applicable | Not yet recruiting | VA Office of Research and Development | 60 | 2028-04-03 | 2026-04-24 |
| Improving Clinic Delivery of HIV-related Anal Health Services PEACHES 2.0 Implementation Strategies - HIV, Gonorrhea | Not applicable | Not yet recruiting | Albert Einstein College of Medicine | 8 | 2028-02-01 | 2026-10-13 |
| Doxycycline Boosted Therapy in Lyme Borreliosis: DoBo Study. Hydroxychloroquin, Placebo, Doxycycline - Lyme Borreliosis, Nervous System | Phase 4 | Not yet recruiting | Radboud University Medical Center | 50 | 2027-03-01 | 2026-08-27 |
| Testing of a New Rapid Antigen Test for Plague in Ituri, Democratic Republic of the Congo. Plague, Bubonic; Plague, Skin | Not yet recruiting | Institute of Tropical Medicine, Belgium | 300 | 2026-12-01 | 2026-09-29 | |
| Optimizing Antibiotic Prescription in STI Clinics Using Rapid POCT cobas® Liat® CT/NG Point-of-Care Test - Chlamydia Trachomatis Infection, Neisseria Gonorrhoeae Infection | Not applicable | Not yet recruiting | Hospices Civils de Lyon | 404 | 2026-12-01 | 2026-10-20 |
| A Clinical Study to Assess the Efficacy of Weekly Doxycycline Prophylaxis to Reduce Bacterial Sexually Transmitted Infections (STI) in Young African Women Doxycycline hyclate, Standard of Care for STI prevention - Sexually Transmitted Infection (STI), Gonorrhea | Phase 3 | Not yet recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 580 | 2026-11-30 | 2026-10-20 |
| A Double-Blind, Placebo-Controlled Study of Nebulized Bacteriophages in Patients With Ventilator-Associated Pneumonia Due to Pseudomonas Aeruginosa Bacteriophages GMP, saline solution (placebo) - Ventilator Associated Bacterial Pneumonia, Pseudomonas Aeruginosa Infection | Phase 3 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 184 | 2026-11-03 | 2026-09-04 |
| Outcomes From Point-of-Care Sexually Transmitted Infection (STI) Testing in an Urban Sexual Health Clinic: A Randomized Trial Point-of-care assay for chlamydia and gonorrhea, Laboratory-based chlamydia and gonorrhea NAAT, CRISPR-based assay - Neisseria Gonorrhoeae Infection, Chlamydia Trachomatis Infection | Not applicable | Not yet recruiting | Massachusetts General Hospital | 400 | 2026-11-01 | 2026-10-06 |
| Congenital Syphilis Treatment Trial (CONSISTENT) in Neonates Benzathine Penicillin, Amoxicillin - Syphilis, Congenital | Phase 4 | Not yet recruiting | University of Alabama at Birmingham | 374 | 2026-11-01 | 2026-09-02 |
| These Studies That Evaluated the Efficacy of Antibiotics for Leptospirosis Treatment. Doxycycline, Placebo - Leptospirosis, Chemoprophylaxis | Phase 4 | Not yet recruiting | Chulalongkorn University | 1000 | 2026-11-01 | 2026-10-08 |
| The Precision Mito- Mito Map COMPASS Study Mito Map Energy Score and Home Functional Assessments - Mitochondrial Diseases, Myalgic Encephalomyelitis Chronic Fatigue Syndrome | Not yet recruiting | AI Agent Vault, Inc. d/b/a Precision Mito | 400 | 2026-11-01 | 2026-10-02 | |
| All-Oral Fluoroquinolone-Based Triple Therapies for Adults With Imaging-Confirmed Osteoarticular Brucellosis Doxycycline + Rifampicin + Ceftriaxone (intravenous therapy for 4 weeks), Triple oral regimen (Doxycycline + Rifampicin + Levofloxacin), Triple oral regimen (Doxycycline + Rifampicin + Moxifloxacin) - Brucellosis, Osteoarticular Brucellosis | Not applicable | Not yet recruiting | The First Affiliated Hospital of Shihezi University | 150 | 2026-11-01 | 2026-10-21 |
| Fluoroquinolone-Doxycycline Oral Treatments for Adults With Uncomplicated Brucellosis Doxycycline + Rifampicin, Doxycycline + Levofloxacin, Doxycycline + Moxifloxacin - Brucellosis | Not applicable | Not yet recruiting | The First Affiliated Hospital of Shihezi University | 200 | 2026-11-01 | 2026-10-21 |
| Assessment of the Acceptability of, and Factors Associated With, Recommended Vaccinations During Pregnancy in Maternity Units in the Ile-de-France Region Vaccination Coverage Among Pregnant Women | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 1605 | 2026-11-01 | 2026-10-20 | |
| Natural History of Trisomy 8-Associated Autoinflammatory Disease (TRIAD) and Related Disorders Trisomy 8 Mosaicism, Trisomy 8 Associated Autoinflammatory Disease | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 750 | 2026-10-27 | 2026-10-22 | |
| Ondansetron to Prevent Oral Rehydration Failure in Children With Cholera Ondansetron, Standard Cholera Care - Cholera (Disorder) | Phase 2 | Not yet recruiting | Public Interest Science Center | 120 | 2026-10-20 | 2026-10-19 |
| Single-center, Open-label Study: Immunogenicity and Safety Observation After Vaccination With ACYW135 Meningococcal Polysaccharide Vaccine in Junior High School Students Aged 13-15 Years MPSV-ACYW - Meningococcal Disease; Meningococcal Meningitis | Phase 4 | Not yet recruiting | Zhejiang Provincial Center for Disease Control and Prevention | 200 | 2026-10-20 | 2026-10-21 |
| A Clinical Study on Immunogenicity Persistence of Adsorbed 5-component Acellular Pertussis, Diphtheria and Tetanus Combined Vaccine Previously received the Tdcp vaccine at age 18 and older, Previously received the Tdcp vaccine at age 12-17, Previously received the Tdcp vaccine at age 6-11 - Diphtheria, Tetanus | Not yet recruiting | CanSino Biologics Inc. | 160 | 2026-10-15 | 2026-08-04 | |
| Aztreonam-Avibactam in Immunocompromised Hosts Aztreonam-Avibactam, Ceftazidime-Avibactam Plus Aztreonam - Enterobacteriaceae Infections, Carbapenem-Resistant Enterobacteriaceae Infection | Recruiting | Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno | 814 | 2026-10-14 | 2026-10-22 | |
| Pilot HIV Self-Testing And Self-collected STI Testing Strategy for Sex Worker Empowerment Study Venue-based, peer-enhanced strategy for integrated HIV self-testing (and self-collected STI testing - HIV, Syphilis | Not applicable | Not yet recruiting | University of North Carolina, Chapel Hill | 232 | 2026-10-01 | 2026-09-18 |
Showing 20 of 1855. Sign in to see all of them.
Whooping Cough (269) · Meningococcal Infections (229) · Tetanus (205) · Diphtheria (200) · Haemophilus Infections (176) · Gonorrhea (158) · Pseudomonas Infections (136) · Chlamydia Infections (132) · Meningitis, Meningococcal (125) · Syphilis (119) · Hepatitis B (114) · Poliomyelitis (103) · Meningitis (101) · Escherichia coli Infections (94) · Lyme Disease (94)
Bacterial Infections and Mycoses (1854) · Bacterial Infections (1813) · Infections (1800) · Neisseriaceae Infections (453) · Respiratory Tract Diseases (429) · Communicable Diseases (398) · Urogenital Diseases (352) · Respiratory Tract Infections (346) · Nervous System Diseases (333) · Pathological Conditions, Signs and Symptoms (326) · Genital Diseases (306) · Spirochaetales Infections (298) · Digestive System Diseases (293) · Neuroinflammatory Diseases (293)
Meningococcal Vaccines (81) · Azithromycin (73) · Tetanus Toxoid (58) · Doxycycline (53) · diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae b conjugate-hepatitis B vaccine (46) · Vaccines (43) · Blood Specimen Collection (39) · Ceftriaxone (36) · 4CMenB vaccine (35) · adacel (34) · Heptavalent Pneumococcal Conjugate Vaccine (27) · 13-valent pneumococcal vaccine (26) · Amoxicillin (26) · Ciprofloxacin (23) · Boostrix (22)
GlaxoSmithKline (194) · Sanofi Pasteur, a Sanofi Company (115) · National Institute of Allergy and Infectious Diseases (NIAID) (66) · Novartis Vaccines (61) · Pfizer (28) · International Vaccine Institute (27) · Sanofi (26) · University of Oxford (24) · International Centre for Diarrhoeal Disease Research, Bangladesh (22) · London School of Hygiene and Tropical Medicine (21) · University of Pittsburgh (21) · University Medical Centre Ljubljana (20) · University of California, San Francisco (19) · Johns Hopkins Bloomberg School of Public Health (18) · Novartis (15)
United States (566) · France (123) · China (101) · United Kingdom (94) · Canada (74) · Germany (73) · Spain (60) · Australia (51) · South Korea (49) · Thailand (49) · Bangladesh (47) · Italy (46) · Belgium (45) · Finland (42) · India (39)
Adriana R Marques, M.D. (8) · Christine Marie George, PhD (5) · Julius Schachter, PhD (5) · Lin Du (5) · Yohei Doi, MD (5) · Brian A Fallon, MD (4) · David Paterson, MD (4)
PMID 35164991, PMID 31110098, PMID 35257644, PMID 19819004, PMID 22461716, PMID 30075748, PMID 31589610, PMID 33020485, PMID 39230271, PMID 40277027, PMID 17287313, PMID 17301105, PMID 17716936, PMID 18532873, PMID 19220138, PMID 19321868, PMID 19389002, PMID 19761838, PMID 19936044, PMID 20412178, PMID 20657177, PMID 21099596, PMID 21177912, PMID 21216000, PMID 21482570, PMID 21775837, PMID 21907255, PMID 21980445, PMID 22327493, PMID 22953007, PMID 23324563, PMID 23357290, PMID 23840001, PMID 23964690, PMID 24161413, PMID 24290843, PMID 25487791, PMID 26702925, PMID 26709158, PMID 27490698, PMID 28340322, PMID 28735965, PMID 29172945, PMID 29191814, PMID 29253560, PMID 29550195, PMID 30061029, PMID 30597021, PMID 31877141, PMID 31945015
2016 (12), 2019 (12), 2008 (9), 2014 (9), 2017 (9), 2023 (9), 2009 (7), 2018 (7), 2015 (4), 2025 (3), 5UG1EY030833 (2), R01AI048789 (2), U19AI084024 (2), UM1AI104681 (2), 1IK2CX002822-01A1 (1)