6 completed, 3 terminated, 3 unknown, 1 not yet recruiting. 4 Not applicable, 3 Phase 2, 2 Phase 3, 2 Phase 4, 1 Early Phase 1.
Follow Cefoxitin: new trials by email Literature Review of Cefoxitin trials Research Report on Cefoxitin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing a Novel Combination Treatment (Arm D) Versus Standard of Care for Intensive Phase Treatment for Mycobacterium Abscessus Pulmonary Disease in People With or Without Cystic Fibrosis in the Finding the Optimal Regimen for Mycobacterium Abscessus Treatment (FORMaT) Adaptive Platform Trial Sulbactam 25mg/kg -Durlobactam 25mg/kg (Every 6 hours), Ceftriaxone for Injection, Amoxicillin - Mycobacterium Abscessus Pulmonary Disease, Mycobacterium Abscessus Infection | Phase 2 | Not yet recruiting | The University of Queensland | 300 | 2027-04-01 | 2026-03-20 |
| Precision Antibiotic Dosing for Appendectomy Cefoxitin - Appendicitis (Diagnosis) | Phase 1 | Completed | University of Michigan | 53 | 2025-02-28 | 2026-11-02 |
| Vaginal Adventitia Reserved and Anatomical Implant Technique of Transvaginal Mesh Procedure for Pelvic Organ Prolapse TVM using the Vaginal Adventitia Reserved and Anatomical Implant Technique - Pelvic Organ Prolapse | Completed | West China Hospital | 589 | 2022-08-01 | 2023-02-01 | |
| Finding the Optimal Regimen for Mycobacterium Abscessus Treatment Amikacin, Tigecycline, Imipenem - Pulmonary Disease Due to Mycobacteria (Diagnosis) | Phase 2 / Phase 3 | Recruiting | The University of Queensland | 300 | 2020-03-02 | 2026-05-11 |
| Two-drug Antibiotic Prophylaxis in Scheduled Cesarean Deliveries Azithromycin 500 mg, Mefoxin 2g - Endometritis, Cesarean Section; Infection | Phase 2 | Unknown | RWJ Barnabas Health at Jersey City Medical Center | 800 | 2019-09-15 | 2019-09-17 |
| Evaluation of the Use of Cefoxitin in Combination in Continuous Parenteral Administration in the Treatment of Bone and Joint Infections bone and joint infection treated with cefoxitin - Antibiotic Reaction, Bone and Joint Infection | Completed | Hospices Civils de Lyon | 35 | 2018-01-01 | 2019-02-22 | |
| Does Cefoxitin or Piperacillin-Tazobactam Prevent Postoperative Surgical Site Infections After Pancreatoduodenectomy? Cefoxitin, Piperacillin-tazobactam - Pancreatic Cancer, Pancreas Cancer | Phase 3 | Completed | Memorial Sloan Kettering Cancer Center | 967 | 2017-11-21 | 2025-10-21 |
| Effectiveness of Prophylactic Antibiotics to Prevent Post Endoscopic Retrograde Cholangio Pancreatography Bacteremia in Biliary Obstruction Patient Pacetin® (cefoxitin), Placebo - Biliary Obstructive Disease Such as Choledocholithiasis, Benign Biliary Stricture | Not applicable | Unknown | Yonsei University | 400 | 2016-12-01 | 2019-01-16 |
| The Comparison of Outcomes of Antibiotic Drugs and Appendectomy (CODA) Trial Cefoxitin, Ertapenem, Moxifloxacin, Tigecycline, Ticarcillin-Clavulanic Acid; Metronidazole plus Cefazolin, Cefuroxime, Ceftriaxone, Cefotaxime, Ciprofloxacin, or Levofloxacin, Appendectomy - Appendicitis | Not applicable | Completed | University of Washington | 1552 | 2016-05-01 | 2023-05-06 |
| Evaluation of the Non-inferiority of Cefoxitin Versus Imipenem/Cilastatin in the Treatment of Urinary Tract Infections Caused by ESBL-producing Escherichia Coli Cefoxitin, imipenem - Urinary Tract Infections | Phase 4 | Terminated | Central Hospital, Nancy, France | 6 | 2016-03-01 | 2017-08-11 |
| Study of Repeated Cefoxitin Administration in Major Abdominal Surgery Using a Microdialysis Technique cefoxitin - Antibiotic Prophylaxis Surgery | Phase 4 | Completed | Poitiers University Hospital | 12 | 2016-02-01 | 2017-06-12 |
| Patients Response to Early Switch To Oral:Osteomyelitis Study oral antibiotics, intravenous antibiotics - Osteomyelitis | Early Phase 1 | Terminated | Julio Ramirez | 11 | 2014-03-06 | 2021-04-06 |
| Immediate Versus Delayed Induction in Term-PROM Using or Not Antibiotic Prophylaxis Cefoxitin, oxytocin/misoprostol - Maternal Infection During Pregnancy (Diagnosis), Neonatal Infection | Not applicable | Unknown | Hospital de Santa Maria, Portugal | 568 | 2013-07-01 | 2016-12-13 |
| Efficacy and Pharmacokinetic/Pharmacodynamic Parameters of Cefoxitin in Women With Acute Pyelonephritis Without Severity Symptoms Due to Extended-spectrum β-lactamase Producing Escherichia Coli Cefoxitin - Acute Pyelonephritis Without Severity Symptoms Due to ESBL-producing E.Coli | Not applicable | Terminated | Assistance Publique - Hôpitaux de Paris | 9 | 2013-05-01 | 2018-01-12 |
Disease (3) · Infections (3) · Appendicitis (2) · Endometritis (2) · Mycobacterium Infections, Nontuberculous (2) · Cholangitis (1) · Chorioamnionitis (1) · Communicable Diseases (1) · Escherichia coli Infections (1) · Fetal Membranes, Premature Rupture (1) · Klatskin Tumor (1) · Lung Diseases (1) · Osteomyelitis (1) · Pancreatic Diseases (1) · Pancreatic Neoplasms (1)
The University of Queensland (2) · Assistance Publique - Hôpitaux de Paris (1) · Central Hospital, Nancy, France (1) · Hospices Civils de Lyon (1) · Hospital de Santa Maria, Portugal (1) · Julio Ramirez (1) · Memorial Sloan Kettering Cancer Center (1) · Poitiers University Hospital (1) · RWJ Barnabas Health at Jersey City Medical Center (1) · University of Michigan (1) · University of Washington (1) · West China Hospital (1) · Yonsei University (1)
United States (5) · France (4) · Australia (1) · Canada (1) · China (1) · Denmark (1) · Israel (1) · Netherlands (1) · Portugal (1) · Singapore (1) · South Korea (1) · Taiwan (1) · United Kingdom (1)
David A Talan, MD (1) · David R Flum, MD, MPH (1) · David Seligson, MD (1) · Julio Ramirez, MD (1) · Manjunath Pai, PharmD (1) · Michael D'Angelica, MD (1) · Tali Wajsfeld, MD (1) · Tristan Ferry, Md,PhD (1) · Wei-min Li, PhD. (1)
PMID 15276398, PMID 15840453, PMID 19588358, PMID 22530208, PMID 29146633, PMID 31220258, PMID 33664081, PMID 35612859, PMID 35796152, PMID 35815898, PMID 36197656, PMID 37078771, PMID 37379001, PMID 37713527, PMID 4902833, PMID 8948280