233 completed, 46 unknown, 28 terminated, 19 recruiting. 71 Not applicable, 64 Phase 2, 46 Phase 1, 45 Phase 4, 44 Phase 3.
Follow Staphylococcal Infections: new trials by email Literature Review of Staphylococcal Infections trials Research Report on Staphylococcal Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Bacterial Decolonization to Prevent Severe Radiation Dermatitis in Head and Neck Squamous Cell Carcinoma Bacterial decolonization, Standard Hygiene Measures - HNSCC | Not applicable | Not yet recruiting | Institut Cancerologie de l'Ouest | 144 | 2027-01-01 | 2026-10-22 |
| Modeling Host-Pathogen Interaction Using Lymphoid Organoids Staphylococcal Infections | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 500 | 2026-11-03 | 2026-10-29 | |
| Farm-originated Antimicrobial Resistance Modeling: Exploring Humans-to-Animal Dissemination Sample collection - Methicillin Resistance in Staphylococcus Aureus (MRSA) | Not applicable | Not yet recruiting | Centre Hospitalier de Saint-Brieuc | 20 | 2026-11-01 | 2026-10-27 |
| Secondary Bacterial Infections and Nasal Colonization in Scabies and Atopic Dermatitis Atopic Dermatitis (AD), Scabies | Not yet recruiting | Istanbul Medeniyet University | 51 | 2026-10-01 | 2026-09-15 | |
| Retention of Vernix Caseosa in Newborns for Primary Prevention of Atopic Dermatitis Retention of Vernix Caseosa After Birth, Removal of Vernix Caseosa After Birth - Atopic Dermatitis | Not applicable | Recruiting | Pontificia Universidad Catolica de Chile | 1383 | 2026-09-29 | 2026-09-30 |
| Intertriginous/Periorificial Dermatoses in Patients With IBD on Anti-TNFα: Relative Abundance of Staphylococcus Aureus Within the Lesion Microbiota and Clinical Correlation (micSPIDER). Inflammatory Bowel Diseases, Crohn's Disease | Not yet recruiting | Centre Hospitalier Universitaire de Nīmes | 82 | 2026-09-01 | 2026-09-10 | |
| Standard Treatment Associated With Phage Therapy Versus Placebo for Diabetic Foot Ulcers Infected by S. Aureus Topical anti-Staphylococcus bacteriophage therapy, Topical placebo corresponding to anti-Staphylococcus bacteriophage therapy - Diabetic Foot, Staphylococcal Infections | Phase 1 / Phase 2 | Not yet recruiting | Centre Hospitalier Universitaire de Nīmes | 60 | 2026-09-01 | 2026-03-20 |
| Comparative Study of Adherence to Antibiotic Therapy Among Pediatric Patients: Hospital Emergency Department vs. Primary Care Center Tonsillitis Acute, Pneumonia - Bacterial | Not yet recruiting | University Hospital, Montpellier | 191 | 2026-09-01 | 2026-07-17 | |
| Thermosensitive Gel Nasal Spray With Stem Cell Exosomes, Mupirocin, and DNase I for Chronic Sinusitis Exosomes (hUC-MSC-Exo), Mupirocin, DNase I - Chronic Rhinosinusitis With Nasal Polyps | Early Phase 1 | Not yet recruiting | The First Affiliated Hospital of Xinxiang Medical College | 108 | 2026-07-01 | 2026-06-09 |
| Rifampin-free Regimen Versus Rifampin-containing Regimen in the Treatment of Staphylococcal Prosthetic Valve Endocarditis Rifampin-free regimen, Rifampin containing regimen - Infective Endocarditis | Phase 3 | Recruiting | Nantes University Hospital | 422 | 2026-06-11 | 2026-10-21 |
| Adjuvant Clopidogrel in Staphylococcus Aureus Bacteremia Clopidogrel, No antiplatelet treatment - Bacteremia Due to Staphylococcus Aureus | Phase 2 | Not yet recruiting | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 230 | 2026-06-01 | 2026-02-05 |
| Unbound Cloxacillin Concentrations During Continuous Infusion Unbound cloxacillin concentration - Staphylococcal Infections | Phase 4 | Recruiting | Emeli Månsson | 25 | 2026-01-14 | 2026-02-17 |
| Light-Activated Antimicrobial Therapy to Prevent Surgical Site Infections - Canada Nasal antimicrobial photodisinfection therapy - Surgical Site Infections, Infections | Not applicable | Completed | Ondine Biomedical Inc. | 401 | 2026-01-13 | 2026-09-15 |
| Comparison of Wound Healing for Diabetic Carbuncle Treated With Incision and Drainage Technique Using Cruciate Incision vs Saucerization Technique Both Followed by Vacuum Assisted Closure. Incision & Drainage Technique Using Cruciate Incision Followed by VAC, Saucerization Technique Followed by VAC - Carbuncle | Not applicable | Recruiting | King Edward Medical University | 124 | 2026-01-02 | 2026-02-23 |
| Safety of Combined Intravenous Antibiotic and Bacteriophage Therapy in Adults With Cystic Fibrosis and Antibiotic-Resistant Lung Infections Intravenous Bacteriophage Cocktail plus Standard IV Antibiotics - CF - Cystic Fibrosis, Klebsiella Pneumoniae Infection | Phase 1 | Not yet recruiting | University of California, San Diego | 30 | 2025-12-31 | 2025-12-12 |
| Linezolid Plus Standard of Care Linezolid 600 mg, Placebo - Staphylococcus Aureus Bloodstream Infections (BSI; Bacteremia) | Not applicable | Recruiting | University Hospital, Basel, Switzerland | 606 | 2025-10-06 | 2026-07-13 |
| Perspectives on Antibiotics and Tracking Symptoms in Children Garmin Smartwatch - Urinary Tract Infection, Cellulitis | Not applicable | Recruiting | Murdoch Childrens Research Institute | 300 | 2025-09-16 | 2026-10-07 |
| Administering NMT to Reestablish Infant Nasal Microbiome Diversity Following Intranasal Mupirocin Treatment Nasal Microbiota Transplant (NMT), Placebo - Staphylococcal Aureus Infection, Microbial Colonization | Phase 1 | Recruiting | Johns Hopkins University | 175 | 2025-08-27 | 2026-08-10 |
| Echocardiography Versus no Echocardiography in S. Aureus Bacteraemia and VIRSTA Score < 3 systematic echocardiography, no echocardiography arm - Staphylococcus Aureus, Bacteremia | Not applicable | Recruiting | Assistance Publique - Hôpitaux de Paris | 700 | 2025-05-14 | 2025-11-24 |
| Decolonization Efficacy of Polyhexanide vs. Mupirocin Polyhexanide, Mupirocin and Chlorhexidine - Staphylococcus Aureus, Colonization, Asymptomatic | Phase 4 | Completed | Swiss Paraplegic Research, Nottwil | 24 | 2025-05-01 | 2026-07-08 |
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Bacteremia (36) · Impetigo (30) · Staphylococcal Skin Infections (30) · Cellulitis (25) · Infections (25) · Sepsis (25) · Abscess (21) · Surgical Wound Infection (20) · Dermatitis, Atopic (15) · Bacterial Infections (14) · Furunculosis (14) · Cross Infection (12) · Pneumonia (11) · Skin Diseases, Bacterial (10)
Bacterial Infections and Mycoses (355) · Gram-Positive Bacterial Infections (348) · Bacterial Infections (341) · Infections (330) · Pathological Conditions, Signs and Symptoms (140) · Pathologic Processes (136) · Skin and Connective Tissue Diseases (106) · Skin Diseases (96) · Inflammation (82) · Skin Diseases, Infectious (80) · Skin Diseases, Bacterial (66) · Systemic Inflammatory Response Syndrome (50) · Staphylococcal Skin Infections (42) · Disease Attributes (41)
Vancomycin (27) · Mupirocin (25) · Daptomycin (20) · Clindamycin (12) · chlorhexidine gluconate (11) · Linezolid (10) · Trimethoprim, Sulfamethoxazole Drug Combination (10) · Blood Specimen Collection (9) · Cefazolin (7) · Chlorhexidine (7) · Cloxacillin (6) · Rifampin (5) · Ceftaroline (4) · Floxacillin (4) · Sodium Hypochlorite (4)
National Institute of Allergy and Infectious Diseases (NIAID) (14) · Centre Hospitalier Universitaire de Saint Etienne (10) · Hospices Civils de Lyon (10) · Nabi Biopharmaceuticals (9) · Basilea Pharmaceutica (8) · Pfizer (8) · Assistance Publique - Hôpitaux de Paris (7) · GlaxoSmithKline (7) · Merck Sharp & Dohme LLC (6) · Centre Hospitalier Universitaire de Nīmes (5) · Henry M. Jackson Foundation for the Advancement of Military Medicine (5) · Washington University School of Medicine (5) · Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (4) · Johns Hopkins University (4) · University Hospital, Basel, Switzerland (4)
United States (144) · France (65) · Germany (24) · Spain (20) · United Kingdom (16) · Canada (15) · Israel (14) · Netherlands (13) · Switzerland (13) · South Africa (12) · Belgium (10) · Mexico (9) · Russia (9) · Australia (8) · Brazil (8)
Matt Hohenboken, MD, PhD (5) · Lisa Beck, MD (3) · Achim J Kaasch, MD (2) · Albert Sotto, MD, PhD (2) · Barbara C Kahl, MD (2) · Daniel M Musher, MD (2) · G. Ralph Corey, MD (2) · Ian A Myles, M.D. (2) · Ian Mr Hayter, BSc (2) · Issam Raad, MD (2) · Jean-Philippe Lavigne, MD PhD (2)
PMID 18444791, PMID 19095213, PMID 20695801, PMID 21115456, PMID 22416054, PMID 27518661, PMID 29380251, PMID 30365584, PMID 30597021, PMID 30716446, PMID 31993453, PMID 34741280, PMID 34922058, PMID 35473663, PMID 39141589, PMID 41433510, PMID 12672715, PMID 14689344, PMID 16310147, PMID 16420547, PMID 16762061, PMID 16914701, PMID 16965625, PMID 17651080, PMID 17719934, PMID 17893153, PMID 18225981, PMID 19118117, PMID 19134433, PMID 19799842, PMID 19936297, PMID 20462352, PMID 20523108, PMID 20686410, PMID 20943877, PMID 21028984, PMID 21115454, PMID 21115455, PMID 21248153, PMID 21444695, PMID 21537018, PMID 21546629, PMID 21828967, PMID 22033452, PMID 22192849, PMID 22198793, PMID 22653459, PMID 22837094, PMID 23085743, PMID 23099329
2014 (2), 2016 (2), 2023 (2), 2018 (1), 2019 (1), 2025 (1), 5UM1AI104681-12 (1), K08AI072043 (1), R21AI179644 (1), R21AR062357 (1), S06GM142120 (1)