501 completed, 179 unknown, 81 recruiting, 59 terminated. 467 Not applicable, 130 Phase 4, 107 Phase 3, 61 Phase 2, 26 Phase 1.
Follow Wound Infection: new trials by email Literature Review of Wound Infection trials Research Report on Wound Infection
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Betadine Vaginal Cleansing Before Cesarean Section to Reduce Postoperative Infectious Morbidity Povidone-iodine 5% solution - Cesarean Section, Surgical Site Infection | Not applicable | Not yet recruiting | Mohamed Mousa Mohamed Mousa | 600 | 2027-05-01 | 2026-07-20 |
| Investigation of the PREVENTIA® Irrigation Solution for Reducing Bacteria in Spinal Surgery With Implants - A Comparative Study Preventia Surgical Solution, 0.9 % NaCl - Surgical Site Infection (SSI), Spine Surgery | Phase 4 | Not yet recruiting | Universität Luzern | 114 | 2027-01-01 | 2026-06-29 |
| Prevention of Vaginal Cuff Infection After Hysterectomy by Addition of Vaginal Clindamycin Clindamycin Vaginal Gel - Surgical Site Infection, Vaginal Cuff Cellulitis | Enrolling by invitation | Baylor Research Institute | 900 | 2026-12-01 | 2026-10-22 | |
| The Use of Tranexamic Acid in Decreasing Wound Complication in Total Ankle Replacement. Transexamic acid, Normal Saline (0.9% NaCl) - Ankle Arthritis, Wound Complication | Phase 2 | Not yet recruiting | Ottawa Hospital Research Institute | 40 | 2026-12-01 | 2026-10-22 |
| Efficacy of Integrating Next Generation Sequencing for Treatment of Surgical Site Infection After Fracture Fixation: NGS diagnostic findings - Next Generation Sequencing (NGS), Surgical Site Infection (SSI) | Phase 3 | Not yet recruiting | Johns Hopkins Bloomberg School of Public Health | 250 | 2026-11-01 | 2026-10-08 |
| Vacuum-Assisted Clipper in Preoperative Hair Removal: Effects on Contamination and Skin Integrity Vacuum-Assisted Electric Shaver (VD-ETM) Method - Microbial Contamination, Environmental Contamination | Not applicable | Not yet recruiting | Bilecik Seyh Edebali Universitesi | 120 | 2026-11-01 | 2026-10-02 |
| Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Study on Nitropaste Using Intraoperative SPY Imaging. Nitroglycerin Ointment 2% - Achilles Tendon Repairs/Reconstructions, Pilon Fracture of Tibia | Phase 1 | Not yet recruiting | Johns Hopkins University | 15 | 2026-11-01 | 2026-03-31 |
| Comparative Study Between Laparoscopic and Open Appendectomy of Complicated Appendicitis Laparoscopic Appendectomy, Open Appendectomy - Appendicitis, Perforated Appendicitis | Not applicable | Not yet recruiting | Assiut University | 100 | 2026-11-01 | 2026-10-16 |
| Evaluation of the Effect of Antibiotic Prophylaxis During Lumpectomy for Breast Cancer: Prospective Randomised Double-blind Noninferiority Study of Placebo vs Cefazolin Cefazolin 2 g Infusion, Placebo infusion of .9 normal saline - Breast Cancer, Breast Surgery | Phase 3 | Not yet recruiting | University Hospital, Clermont-Ferrand | 1600 | 2026-11-01 | 2026-10-27 |
| Povidone-Iodine and Ozonated Distilled Water Irrigation in the Management of Maxillofacial Space Infections Incision and drainage + Povidone-iodine irrigation, Incision and drainage + ozonated distilled - Infection, Surgical Site | Not applicable | Not yet recruiting | Alexandria University | 26 | 2026-10-28 | 2026-10-29 |
| Cyanoacrylate Skin Adhesive After Mohs Surgery or Wide Local Excision Cyanoacrylate Skin Adhesive, Fast Gut Running Epidermal Suture Closure, Vicryl Rapide Running Epidermal Suture Closure - Surgical Site Infection, Skin Cancer | Not applicable | Not yet recruiting | University of Minnesota | 300 | 2026-10-26 | 2026-10-20 |
| DRONE-WOUND Study: Severe Infection After Drone-Related Combat Trauma Combat Related Symptoms, Combat Trauma | Not yet recruiting | Ukrainian Society of Regional Anesthesia and Pain Therapy | 500 | 2026-10-23 | 2026-07-16 | |
| Timing of Cesarean Wound Dressing Removal on Wound Healing in Women With BMI ≥ 30 kg/m² Cesarean Section, Surgical Wound Infection | Not yet recruiting | Assiut University | 726 | 2026-10-01 | 2026-09-29 | |
| Antibiotic Tissue Penetration and Tissue Response in Head and Neck Infection and Reconstructive Surgery Cefuroxime, Dicloxacillin, Cloxacillin - Surgical Wound Infection, Neck Infection | Phase 4 | Not yet recruiting | Tejs Ehlers Klug | 16 | 2026-10-01 | 2026-10-26 |
| A Study of Amicidin-β Topical Solution for Patients With Surgical or Traumatic Wound Infections Amicidin-β topical solution - 15 mL, Amicidin-β topical solution - 50 mL, Standard of Care (SOC) - Surgical Wound Infection, Traumatic Wound Infection | Phase 1 | Recruiting | Macro Biologics, Inc. | 44 | 2026-09-30 | 2026-08-17 |
| Perioperative Pharmacokinetic/Pharmacodynamic Target Attainment of Piperacillin During Major Hepatic and Pancreatic Surgery Antibiotic Prophylaxis, Pancreatic Surgey | Recruiting | Central Hospital, Nancy, France | 60 | 2026-09-25 | 2026-10-02 | |
| Gene Expression Analysis of Biofilm Formation and Antimicrobial Resistance in Clinical Methicillin-Resistant Staphylococcus Aureus swab from lesion, Biochemical reactions, Antibiotic sensitivity - Staphylococcal Aureus Infection, Surgical Site Infection (SSI) | Not yet recruiting | Sohag University | 100 | 2026-09-20 | 2026-09-01 | |
| Infection Prevention for "Bellwether" Surgery in Ethiopia Surgical Site Infection Prevention and Control (IPC) Bundle - Ceserean Section, Lower Limb Fractures | Not yet recruiting | Karolinska Institutet | 1000 | 2026-09-01 | 2026-06-15 | |
| Mechanical Bowel Prep Randomized Study IVA+OA versus IVA+MBP+OA - Colorectal Surgery | Not applicable | Not yet recruiting | Mount Sinai Hospital, Canada | 1062 | 2026-09-01 | 2026-06-22 |
| Comparative Outcomes of Mammary Artery Harvesting: Infection, Occlusion Rates and Thoracic Pain Assessment Skeletonized LIMA Harvesting, Non-Skeletonized LIMA Harvesting - Coronary Artery Disease, Coronary Artery Bypass Grafting | Not applicable | Withdrawn | Hamilton Health Sciences Corporation | 2026-09-01 | 2026-07-28 |
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Surgical Wound Infection (726) · Infections (67) · Postoperative Complications (43) · Surgical Wound (37) · Wounds and Injuries (36) · Incisional Hernia (23) · Staphylococcal Infections (22) · Cellulitis (21) · Colorectal Neoplasms (20) · Bacterial Infections (19) · Abscess (18) · Cross Infection (18) · Pain, Postoperative (17) · Diabetes Mellitus (16)
Infections (865) · Pathological Conditions, Signs and Symptoms (788) · Pathologic Processes (779) · Postoperative Complications (706) · Wounds and Injuries (73) · Neoplasms (66) · Signs and Symptoms (65) · Digestive System Diseases (62) · Neoplasms by Site (60) · Skin and Connective Tissue Diseases (54) · Gastrointestinal Diseases (53) · Intestinal Diseases (48) · Bacterial Infections and Mycoses (42) · Inflammation (41)
Cefazolin (36) · Vancomycin (36) · Negative-Pressure Wound Therapy (31) · Povidone-Iodine (31) · Saline Solution (25) · chlorhexidine gluconate (25) · Metronidazole (22) · Chlorhexidine (17) · Sodium Chloride (17) · Anti-Bacterial Agents (16) · Standard of Care (15) · Cefuroxime (14) · Ethanol (14) · Amoxicillin-Potassium Clavulanate Combination (12) · Clindamycin (10)
Assiut University (12) · Hospital de Granollers (12) · Insel Gruppe AG, University Hospital Bern (12) · Ain Shams University (9) · Washington University School of Medicine (9) · Hospital General Universitario Elche (6) · Odense University Hospital (6) · Pfizer (6) · University Hospital, Basel, Switzerland (6) · University of Birmingham (6) · Zurex Pharma, Inc. (6) · Charite University, Berlin, Germany (5) · Georgetown University (5) · Ottawa Hospital Research Institute (5) · The University of Texas Medical Branch, Galveston (5)
United States (264) · Spain (51) · Canada (40) · Turkey (Türkiye) (36) · Egypt (34) · Pakistan (34) · Germany (33) · Switzerland (32) · France (29) · Italy (27) · United Kingdom (27) · China (22) · Sweden (21) · Brazil (20) · Israel (20)
Daniela F Veiga, MD, PhD (5) · G. Ralph Corey, MD (4) · Christopher Attinger, MD (3) · David P Nicolau, PharmD (3) · Methodius G Tuuli, MD, MPH (3) · Andreas Widmer, Prof. Dr. MD (2) · Aneel Bhangu (2) · Brian Schmidt, DPM (2) · Christoph Justinger, M.D. (2) · Craig R Dufresne, MD (2) · Daniel I Sessler, M.D. (2) · David Melnick, MSD (2)
PMID 41159585, PMID 36748942, PMID 40260835, PMID 32335895, PMID 32580252, PMID 10219875, PMID 30597021, PMID 30716446, PMID 34741280, PMID 34905144, PMID 34922058, PMID 11294711, PMID 19231586, PMID 20695801, PMID 21115456, PMID 22549748, PMID 23231938, PMID 24201395, PMID 24754343, PMID 24897082, PMID 25379844, PMID 26551196, PMID 26844840, PMID 27370913, PMID 27585969, PMID 29358292, PMID 29406579, PMID 31481559, PMID 32259266, PMID 32787892, PMID 37147462, PMID 9188971, PMID 1015603, PMID 10167360, PMID 10231213, PMID 10571434, PMID 10686977, PMID 10898201, PMID 11074996, PMID 11149772, PMID 11257737, PMID 11525858, PMID 12046489, PMID 12439804, PMID 12573039, PMID 12603990, PMID 12641893, PMID 12776983, PMID 12963381, PMID 1332552
2019 (4), 2018 (3), 2025 (3), 2014 (2), K23DK131261 (2), 2015 (1), 2017 (1), P50HL073996 (1), R01DK125835 (1), R01HD086007 (1), R21AR068632 (1), R21DE032844 (1), R44AR047499 (1), R44GM095005 (1), T32AI078875 (1)