29 completed, 7 recruiting, 2 enrolling by invitation, 2 not yet recruiting. 46 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 46 | Completed 29, Recruiting 7, Enrolling by invitation 2, Not yet recruiting 2, Terminated 2, Withdrawn 2, Active not recruiting 1, Unknown 1 |
Follow Tobacco Use: new trials by email Literature Review of Tobacco Use trials Research Report on Tobacco Use
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Smoking Cessation Medication And Rewards Using a Teamlet to Treat Tobacco Use Disorder (SMARTTT 2.0) Among Persons With HIV: A Multi-site Hybrid Type 2 Effectiveness-implementation Trial nicotine patch, nicotine gum, nicotine lozenge, varenicline, bupropion, Multi-target Contingency Management, Teamlet booster - Tobacco Use Disorder/Cigarette Smoking, HIV | Phase 4 | Not yet recruiting | Yale University | 794 | 2027-09-30 | 2026-09-23 |
| Evaluating an Innovative Tobacco Treatment Approach for Veterans in Substance Use Treatment Healthy Changes Nicotine Replacement Therapy (NRT), Cessation Treatment Nicotine Replacement Therapy (NRT), Cessation Treatment Counseling - Cigarette Smoking, Veterans | Phase 4 | Not yet recruiting | VA Office of Research and Development | 112 | 2027-04-01 | 2026-09-14 |
| Varenicline for Smoking Reduction in Veterans Not Ready To Quit Motivation-Phase Varenicline, Motivation-Phase Nicotine Mini-Lozenge, Cessation-Phase Combination Nicotine Replacement Therapy (NRT) - Veterans, Tobacco Use Disorder | Phase 4 | Recruiting | VA Office of Research and Development | 400 | 2026-08-17 | 2026-08-31 |
| Piloting Novel Interventional Strategies to Improve Nicotine Pouches as a Substitute for Smoking Nicotine replacement therapy patches, Oral nicotine pouches - Smoking ( Cigarette) | Phase 4 | Enrolling by invitation | Medical University of South Carolina | 10 | 2026-06-26 | 2026-07-06 |
| Extended Intervention for Tobacco Use (EXIT) for People Experiencing Homelessness Nicotine Replacement Therapy (NRT), Wellness Coaching - Tobacco Cessation, Tobacco Abstinence | Phase 4 | Recruiting | University of California, San Francisco | 150 | 2025-11-14 | 2025-11-21 |
| tDCS Plus Varenicline for Smoking Cessation Active Transcranial Direct Current Stimulation (tDCS), Varenicline 1mg BID, Sham Transcranial Direct Current Stimulation (tDCS) - Nicotine Dependence, Tobacco Smoking | Phase 4 | Recruiting | Centre for Addiction and Mental Health | 160 | 2025-03-10 | 2025-08-12 |
| Beta-Adrenergic Modulation of Drug Cue Reactivity Propranolol, Nicotine Patch, Placebo Propranolol - Tobacco Use Disorder, Nicotine Dependence | Phase 4 | Recruiting | University of Oklahoma | 80 | 2024-11-26 | 2026-04-28 |
| Impact of Semaglutide on Tobacco Use and Related Health Behaviors Semaglutide, Placebo - Tobacco Use | Phase 4 | Recruiting | University of Oklahoma | 40 | 2024-07-01 | 2025-08-27 |
| Tobacco Cessation at FDNY opt out enrollment, tailored counseling, varenicline started prior to target quit date, opt in enrollment, non-tailored counseling, varenicline started prior to target quit date - Tobacco Use, Tobacco Smoking | Phase 4 | Completed | Albert Einstein College of Medicine | 23 | 2024-05-31 | 2026-11-05 |
| Smoking Cessation Program in the Construction Sector Nicorette, Tobacco Quit-line, Brief Behavioral Counseling - Smoking Cessation, Tobacco Use Cessation | Phase 4 | Active not recruiting | University of Miami | 608 | 2024-04-10 | 2026-08-21 |
| Effectiveness of Combined Tobacco Treatment in Hospitalized Subjects Bupropion, Nicotine replacement therapy (Nicotine patches) - Tobacco Smoking, Tobacco Withdrawal | Phase 4 | Unknown | National Institute of Respiratory Diseases, Mexico | 134 | 2024-01-15 | 2024-02-23 |
| BREATHE 2 Clinic Stop-Smoking Treatment Outreach Study Text message smoking treatment, Nicotine replacement therapy sampling, Wisconsin Tobacco QuitLine Referral - Quitting Smoking, Smoking Cessation | Phase 4 | Completed | University of Wisconsin, Madison | 12376 | 2023-07-24 | 2026-06-26 |
| Integrating Tobacco Use Cessation Into HIV Care and Treatment in Kisumu County, Kenya Tobacco Use Cessation Counselling Sessions, Bupropion, Nicotine patch - Tobacco Use Cessation, Tobacco Use | Phase 4 | Completed | University of California, San Francisco | 580 | 2023-05-16 | 2025-07-02 |
| Smoking Cessation and Menstrual Cycle Phase Timing of nicotine replacement therapy start date, Nicotine Replacement Therapy Agent - Nicotine Dependence, Tobacco Smoking | Phase 4 | Recruiting | Centre for Addiction and Mental Health | 1200 | 2022-11-30 | 2026-03-19 |
| Tobacco Cessation Treatment Preferences Among Veteran Smokers Personalized Smoking Cessation Facilitation Meetings, Personalized Smoking Cessation Pharmacotherapy, Personalized Text Messaging Support - Tobacco Use | Phase 4 | Completed | VA Office of Research and Development | 30 | 2022-05-02 | 2024-05-07 |
| Opioids and Smoking Cessation Nicotine patch - Smoking, Smoking Cessation | Phase 4 | Withdrawn | University of Houston | 2020-12-01 | 2022-05-20 | |
| Antibiotic Prophylaxis in High-Risk Arthroplasty Patients Cephalexin, Doxycycline, Cefadroxil - Infections Joint Prosthetic, Overweight or Obesity | Phase 4 | Enrolling by invitation | Mayo Clinic | 4618 | 2020-06-11 | 2026-07-06 |
| Health Systems Reach Interventions Project Varenicline, Combination nicotine patch and nicotine mini-lozenge treatment, Monetary incentives for initiating treatment - Smoking, Cigarette, Smoking Cessation | Phase 4 | Completed | University of Wisconsin, Madison | 210 | 2020-03-11 | 2026-10-05 |
| Mindfulness Based Smoking Cessation Among Cancer Survivors Nicoderm C-Q Transdermal Product, Orientation session, Craving-to-Quit app - Tobacco Smoking | Phase 4 | Terminated | University of Miami | 20 | 2019-09-28 | 2025-09-09 |
| PARQuit Smoking Cessation Intervention for Adults With Serious Mental Illness Videogame-based physical activity, Sedentary videogame, Bupropion - Smoking Cessation, Smoking, Tobacco | Phase 4 | Completed | University of California, San Francisco | 108 | 2019-07-08 | 2026-07-17 |
Showing 20 of 46. Sign in to see all of them.
Cigarette Smoking (25) · Tobacco Smoking (15) · Smoking Cessation (13) · Tobacco Use Disorder (13) · Smoking (10) · Schizophrenia (6) · Tobacco Use Cessation (4) · Smoking Reduction (3) · Substance-Related Disorders (3) · Neoplasms (2) · Obesity (2) · Alcohol Drinking (1) · Asthma (1) · Attention Deficit Disorder with Hyperactivity (1)
Behavior (46) · Smoking (30) · Tobacco Smoking (24) · Mental Disorders (20) · Health Behavior (18) · Chemically-Induced Disorders (15) · Substance-Related Disorders (12) · Schizophrenia Spectrum and Other Psychotic Disorders (6) · Pathological Conditions, Signs and Symptoms (3) · Signs and Symptoms (3) · Body Weight (2) · Immune System Diseases (2) · Nutrition Disorders (2) · Nutritional and Metabolic Diseases (2)
Tobacco Use Cessation Devices (12) · Varenicline (11) · Nicotine Replacement Therapy (8) · Bupropion (7) · Nicotine Chewing Gum (7) · Counseling (3) · Nicotine (3) · Behavior Therapy (2) · Ethanol (2) · Propranolol (2) · BID protein, human (1) · Cefadroxil (1) · Cephalexin (1) · Cognitive Behavioral Therapy (1) · Community Resources (1)
Centre for Addiction and Mental Health (3) · Duke University (3) · University of California, San Francisco (3) · VA Office of Research and Development (3) · Massachusetts General Hospital (2) · Nathan Kline Institute for Psychiatric Research (2) · Swedish Match AB (2) · University of Miami (2) · University of Oklahoma (2) · University of Wisconsin, Madison (2) · Albert Einstein College of Medicine (1) · Chinese University of Hong Kong (1) · Corporal Michael J. Crescenz VA Medical Center (1) · Mayo Clinic (1) · Medical University of South Carolina (1)
United States (36) · Canada (3) · China (1) · Germany (1) · Hong Kong (1) · Israel (1) · Italy (1) · Kenya (1) · Mexico (1) · Serbia (1) · United Kingdom (1)
Jason A Oliver, PhD (2) · Laurie A Zawertailo, PhD (2) · Taghrid Asfar, MD (2) · Alberto Papi, MD (1) · Amanda Palmer, PhD (1) · Andrew H Rogers, M.A. (1) · Brian Hitsman, Ph.D. (1) · Ching Ching Chan, FHKAM (1) · Danielle E McCarthy, PhD (1) · David C Carter, MD (1) · David Goldfarb, PhD (1) · E. Jennifer Edelman, MD, MHS (1) · Elyse R Park, PhD (1) · Francis J McClernon, Ph.D. (1) · Frank H Farmer, Jr, MD, Ph D, CPI (1)
PMID 37142273, PMID 10191796, PMID 10417762, PMID 10493090, PMID 10510989, PMID 10581887, PMID 10740940, PMID 10748642, PMID 10791509, PMID 10812284, PMID 10885042, PMID 10901493, PMID 11176814, PMID 11236847, PMID 11260806, PMID 11516593, PMID 12010856, PMID 1202204, PMID 12028847, PMID 12047734, PMID 12438835, PMID 12492263, PMID 12814497, PMID 1453243, PMID 15010446, PMID 1511534, PMID 15370156, PMID 15370939, PMID 15820329, PMID 1613610, PMID 16504277, PMID 1668228, PMID 17008196, PMID 17373404, PMID 17373408, PMID 17420431, PMID 1772149, PMID 17874878, PMID 18715746, PMID 18838243, PMID 18931942, PMID 19056188, PMID 19251401, PMID 19373517, PMID 19394037, PMID 19400961, PMID 19440285, PMID 19549054, PMID 20524884, PMID 21143432
P01CA180945 (2), 2023 (1), K23DA034034 (1), R01CA184211 (1), R01DA024667 (1), R01DA038442 (1), R01DA053342 (1), R01HL081522 (1), R21CA119112 (1), R21OH012256 (1), U01CA261620 (1)