194 completed, 21 unknown, 19 recruiting, 12 not yet recruiting. 187 Not applicable, 27 Phase 3, 24 Phase 2, 20 Phase 4, 10 Phase 1.
Follow this condition Literature Review of Tobacco Use Cessation trials Research Report on Tobacco Use Cessation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| VergeRx for Smokers Not Ready to Quit VergeRx, SmokefreeTXT, NRT Lozenge (Combination) - Tobacco Use Cessation | Not applicable | Not yet recruiting | University of Virginia | 592 | 2027-12-01 | 2026-07-09 |
| A Web-Based Text Messaging for Tobacco Cessation in Rural Mississippi Motivational text messaging for tobacco cessation, Non-specific text messaging - Tobacco Cessation | Not applicable | Not yet recruiting | University of Mississippi Medical Center | 150 | 2026-12-01 | 2026-02-24 |
| Quit With Sense: Using Mindful Smoking and Wearable Device for Smoking Cessation Mindful Smoking and Sensor-Band Intervention, Smoking Cessation Information - Smoking Cessation, Cigarette Smoking | Not applicable | Not yet recruiting | University of Minnesota | 30 | 2026-11-10 | 2026-10-13 |
| Multi-Theory Model-Based AI Agent Intervention for Smoking Cessation in Early-Stage Cancer Patients MTM-Based AI Agent for smoking cessation, Counseling - Smoking Cessation, Early-Stage Cancer | Not applicable | Not yet recruiting | Sun Yat-sen University | 156 | 2026-10-01 | 2026-09-18 |
| Evaluation of Community Health Worker Support to Help People With Serious Mental Illness to Quit Smoking Integrated CHW Support intervention, Enhanced usual care (EUC) - Nicotine Dependance, Serious Mental Illness | Not applicable | Not yet recruiting | Massachusetts General Hospital | 937 | 2026-10-01 | 2026-08-27 |
| Automating Tobacco Cessation in Primary Care Tobacco counseling resources - Tobacco Use, Tobacco Use Cessation | Not applicable | Recruiting | University of Pennsylvania | 4800 | 2026-09-24 | 2026-10-21 |
| Evaluation of Dependence and Nicotine Replacement Therapy-Supported Cessation Efforts Among Regular Electronic Cigarette Use Nicotine Replacement Therapies, Brief Behavioral Counseling - E Cigarette Use, Cessation, Tobacco | Phase 4 | Not yet recruiting | West Virginia University | 100 | 2026-09-01 | 2026-08-26 |
| Effectiveness of Oral Nicotine Pouches as a Cessation Tool Among Adult Tobacco Users in Pakistan Velo 6 mg Oral Nicotine Pouches, Motivational Counselling - Tobacco Cessation, Smoking Cessation | Not applicable | Not yet recruiting | Cyntax Health Projects PVT LTD | 148 | 2026-09-01 | 2026-08-25 |
| Feasibility of a Medical-Legal Partnership Model to Connect Coal Miners QuitAid QuitAid (pharmacist-delivered MTM), Nicotine Replacement Therapy (NRT) - Tobacco Use Cessation, Tobacco Use Disorder | Not applicable | Not yet recruiting | University of Virginia | 120 | 2026-09-01 | 2026-07-10 |
| Adaptation and Testing of a Novel Text-based Tobacco Cessation and Education Intervention in Kenyan Emergency Department Patients Text2Quit-Kenya - Tobacco Use, Tobacco Use Cessation | Not applicable | Not yet recruiting | Yale University | 285 | 2026-08-01 | 2026-08-06 |
| Optimizing Treatment of Co-occurring Smoking and Unhealthy Alcohol Use Among PWH in Nairobi, Kenya Cystine, Positively Smoke Free, Placebo - HIV, Tobacco Use | Phase 3 | Not yet recruiting | University of Chicago | 300 | 2026-07-31 | 2026-07-30 |
| Implementation of Tobacco Cessation Programming at Community Behavioral Health Sites Enhanced Courage to Quit - Nicotine Use Disorder, Smoking Cessation | Not applicable | Recruiting | University of Chicago | 24 | 2026-07-20 | 2026-07-07 |
| Community Gateway to Health Study Tools and Training for Cancer Control, Enhancing Social Capital and Civic Engagement - Breast Cancer Screening, Cervical Cancer Screening | Not applicable | Enrolling by invitation | Harvard School of Public Health (HSPH) | 100 | 2026-06-02 | 2026-07-06 |
| Community-based Mobile-assisted Brief Intervention for Smoking Cessation Brief cessation advice + self-help booklet, Opt-out referral, Mobile chat messaging - Smoking &Amp; Tobacco Cessation | Not applicable | Active not recruiting | National University of Singapore | 100 | 2026-02-04 | 2026-07-16 |
| Health Warnings and Counseling for Smoking Cessation Graphical health warnings, Graphical health warnings plus pharmacist-led counselling, Routine pharmacy services (no intervention) - Tobacco Cessation, Health Warning Label | Not applicable | Recruiting | Hitotsubashi University | 3400 | 2026-02-01 | 2026-04-14 |
| Trauma-Informed Care for Smoking Cessation for Pregnancy Expired carbon monoxide (CO), Interviews, Questionnaires - Smoking Cessation, Tobacco Smoking | Not applicable | Recruiting | University of California, San Francisco | 20 | 2025-11-19 | 2026-09-10 |
| Extended Intervention for Tobacco Use (EXIT) for People Experiencing Homelessness Nicotine Replacement Therapy (NRT), Wellness Coaching - Tobacco Cessation, Tobacco Abstinence | Phase 4 | Recruiting | University of California, San Francisco | 150 | 2025-11-14 | 2025-11-21 |
| Developing a Scalable Tobacco Cessation Program for Cancer Survivors and Caregivers Nicotine cessation program - Nicotine Use, Tobacco Use | Not applicable | Recruiting | University of Florida | 204 | 2025-07-11 | 2026-05-15 |
| CONNECT Cancer Survivors With Tobacco Treatment ELEVATE, ELEVATE-S - Tobacco Use, Tobacco Use Cessation | Not applicable | Active not recruiting | Washington University School of Medicine | 3543 | 2025-07-01 | 2026-07-10 |
| Cannabis-Tobacco Co-Use Treatment Study Varenicline, Counseling, Psychosocial modules - Tobacco Use Disorder, Tobacco Use Cessation | Phase 3 | Recruiting | Medical University of South Carolina | 200 | 2025-05-06 | 2026-04-03 |
Showing 20 of 274. Sign in to see all of them.
Smoking Cessation (91) · Tobacco Use Disorder (66) · Tobacco Use (49) · Smoking (47) · Tobacco Smoking (24) · Cigarette Smoking (16) · Vaping (10) · Behavior, Addictive (7) · Motor Activity (7) · Substance-Related Disorders (7) · Neoplasms (6) · Mental Disorders (5) · Obesity (5) · Acquired Immunodeficiency Syndrome (4)
Behavior (272) · Health Behavior (272) · Mental Disorders (70) · Chemically-Induced Disorders (69) · Substance-Related Disorders (62) · Smoking (31) · Pathological Conditions, Signs and Symptoms (17) · Tobacco Use (16) · Pathologic Processes (13) · Disease Attributes (11) · Immune System Diseases (9) · Lung Diseases (9) · Respiratory Tract Diseases (9) · Infections (8) · Nutritional and Metabolic Diseases (8)
Tobacco Use Cessation Devices (36) · Nicotine Replacement Therapy (18) · Varenicline (14) · Surveys and Questionnaires (12) · Nicotine (10) · Bupropion (9) · Counseling (8) · Nicotine Chewing Gum (7) · Standard of Care (6) · Crisis Intervention (5) · Motivational Interviewing (5) · Behavior Therapy (3) · Cognitive Behavioral Therapy (3) · corticosteroid hormone-induced factor (3) · Interviews as Topic (2)
Mayo Clinic (11) · University of California, San Francisco (11) · M.D. Anderson Cancer Center (10) · University of Minnesota (10) · Yale University (9) · Duke University (7) · Harvard School of Public Health (HSPH) (7) · Washington University School of Medicine (6) · Oregon Research Institute (5) · University of California, San Diego (5) · VA Office of Research and Development (5) · Massachusetts General Hospital (4) · NYU Langone Health (4) · National Institute on Drug Abuse (NIDA) (4) · Tata Memorial Hospital (4)
United States (189) · Canada (9) · France (9) · India (9) · Spain (6) · Sweden (6) · Norway (5) · Brazil (4) · Kenya (4) · Hong Kong (3) · Pakistan (3) · Turkey (Türkiye) (3) · Vietnam (3) · Bangladesh (2) · Belgium (2)
Shu-Hong Zhu, Ph.D. (5) · Devon Noonan, PhD (4) · Jamie Ostroff, PhD (3) · Li-Shiun Chen, M.D., MPH, ScD (3) · Donna Shelley, MD, MPH (2) · Gary L. Humfleet, PhD (2) · Gauravi A Mishra, Assoc Prof (2) · Glorian Sorensen, PhD, MPH (2) · Isabel C Scarinci, PhD (2) · Janice Tsoh, PhD (2) · John R Hughes, MD (2) · Judith J Prochaska, PhD, MPH (2) · Man Ping Wang, PhD (2) · Marcel A. de Dios, PHD (2)
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K01CA160670 (2), R01DA025156 (2), 1UG3HL151302-01 (1), 2017 (1), 2023 (1), 4UH3HL151302-04 (1), K12DA041449 (1), K23DA018691 (1), K23DA032578 (1), K99DA044277 (1), P30CA044579 (1), P50CA084718 (1), P50CA244431 (1), P50DA009253 (1), P50DA033942 (1)